-
1
-
-
40949133230
-
IL4 gene delivery to the CNS recruits regulatory T cells and induces clinical recovery in mouse models of multiple sclerosis
-
Butti E, Bergami A, Recchia A, Brambilla E, Del Carro U, Amadio S, Cattalini A, Esposito M, Stornaiuolo A, Comi G, Pluchino S, Mavilio F, Martino G, Furlan R. 2008. IL4 gene delivery to the CNS recruits regulatory T cells and induces clinical recovery in mouse models of multiple sclerosis. Gene Ther 15(7):504-515.
-
(2008)
Gene Ther
, vol.15
, Issue.7
, pp. 504-515
-
-
Butti, E.1
Bergami, A.2
Recchia, A.3
Brambilla, E.4
Del Carro, U.5
Amadio, S.6
Cattalini, A.7
Esposito, M.8
Stornaiuolo, A.9
Comi, G.10
Pluchino, S.11
Mavilio, F.12
Martino, G.13
Furlan, R.14
-
2
-
-
72049110764
-
Chronic caffeine treatment attenuates experimental autoimmune encephalomyelitis induced by guinea pig spinal cord homogenates in Wistar rats
-
Chen GQ, Chen YY, Wang XS, Wu SZ, Yang HM, Xu HQ, He JC, Wang XT, Chen JF, Zheng RY. 2010. Chronic caffeine treatment attenuates experimental autoimmune encephalomyelitis induced by guinea pig spinal cord homogenates in Wistar rats. Brain Res 1309:116-125.
-
(2010)
Brain Res
, vol.1309
, pp. 116-125
-
-
Chen, G.Q.1
Chen, Y.Y.2
Wang, X.S.3
Wu, S.Z.4
Yang, H.M.5
Xu, H.Q.6
He, J.C.7
Wang, X.T.8
Chen, J.F.9
Zheng, R.Y.10
-
3
-
-
4344681450
-
Evidence that estrogen suppresses rho-kinase function in the cerebral circulation in vivo
-
Chrissobolis S, Budzyn K, Marley PD, Sobey CG. 2004. Evidence that estrogen suppresses rho-kinase function in the cerebral circulation in vivo. Stroke 35(9):2200-2205.
-
(2004)
Stroke
, vol.35
, Issue.9
, pp. 2200-2205
-
-
Chrissobolis, S.1
Budzyn, K.2
Marley, P.D.3
Sobey, C.G.4
-
4
-
-
77952403219
-
Estradiol inhibits ongoing autoimmune neuroinflammation and NFkappaB-dependent CCL2 expression in reactive astrocytes
-
Giraud SN, Caron CM, Pham-Dinh D, Kitabgi P, Nicot AB. 2010. Estradiol inhibits ongoing autoimmune neuroinflammation and NFkappaB-dependent CCL2 expression in reactive astrocytes. Proc Natl Acad Sci USA 107(18):8416-8421.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.18
, pp. 8416-8421
-
-
Giraud, S.N.1
Caron, C.M.2
Pham-Dinh, D.3
Kitabgi, P.4
Nicot, A.B.5
-
5
-
-
33746729791
-
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
-
Gold R, Linington C, Lassmann H. 2006. Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 129(Part 8):1953-1971.
-
(2006)
Brain
, vol.129
, Issue.PART 8
, pp. 1953-1971
-
-
Gold, R.1
Linington, C.2
Lassmann, H.3
-
6
-
-
68049098297
-
Estrogen and testosterone therapies in multiple sclerosis
-
Gold SM, Voskuhl RR. 2009. Estrogen and testosterone therapies in multiple sclerosis. Prog Brain Res 175:239-251.
-
(2009)
Prog Brain Res
, vol.175
, pp. 239-251
-
-
Gold, S.M.1
Voskuhl, R.R.2
-
7
-
-
70349559752
-
Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha (ERalpha)
-
Gold SM, Sasidhar MV, Morales LB, Du S, Sicotte NL, Tiwari-Woodruff SK, Voskuhl RR. 2009. Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha (ERalpha). Lab Invest 89(10):1076-1083.
-
(2009)
Lab Invest
, vol.89
, Issue.10
, pp. 1076-1083
-
-
Gold, S.M.1
Sasidhar, M.V.2
Morales, L.B.3
Du, S.4
Sicotte, N.L.5
Tiwari-Woodruff, S.K.6
Voskuhl, R.R.7
-
8
-
-
0038322504
-
Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis
-
Greenwood J, Walters CE, Pryce G, Kanuga N, Beraud E, Baker D, Adamson P. 2003. Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis. FASEB J 17(8):905-907.
-
(2003)
FASEB J
, vol.17
, Issue.8
, pp. 905-907
-
-
Greenwood, J.1
Walters, C.E.2
Pryce, G.3
Kanuga, N.4
Beraud, E.5
Baker, D.6
Adamson, P.7
-
9
-
-
59349088328
-
Validation of a novel biomarker for acute axonal injury in experimental autoimmune encephalomyelitis
-
Gresle MM, Shaw G, Jarrott B, Alexandrou EN, Friedhuber A, Kilpatrick TJ, Butzkueven H. 2008. Validation of a novel biomarker for acute axonal injury in experimental autoimmune encephalomyelitis. J Neurosci Res 86(16):3548-3555.
-
(2008)
J Neurosci Res
, vol.86
, Issue.16
, pp. 3548-3555
-
-
Gresle, M.M.1
Shaw, G.2
Jarrott, B.3
Alexandrou, E.N.4
Friedhuber, A.5
Kilpatrick, T.J.6
Butzkueven, H.7
-
10
-
-
41949128622
-
Biological markers for axonal degeneration in CSF and blood of patients with the first event indicative for multiple sclerosis
-
Hein Nee Maier K, Kohler A, Diem R, Sattler MB, Demmer I, Lange P, Bahr M, Otto M. 2008. Biological markers for axonal degeneration in CSF and blood of patients with the first event indicative for multiple sclerosis. Neurosci Lett 436(1):72-76.
-
(2008)
Neurosci Lett
, vol.436
, Issue.1
, pp. 72-76
-
-
Hein Nee Maier, K.1
Kohler, A.2
Diem, R.3
Sattler, M.B.4
Demmer, I.5
Lange, P.6
Bahr, M.7
Otto, M.8
-
11
-
-
42649135852
-
Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: Implications for multiple sclerosis
-
Herrero-Herranz E, Pardo LA, Gold R, Linker RA. 2008. Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: Implications for multiple sclerosis. Neurobiol Dis 30(2):162-173.
-
(2008)
Neurobiol Dis
, vol.30
, Issue.2
, pp. 162-173
-
-
Herrero-Herranz, E.1
Pardo, L.A.2
Gold, R.3
Linker, R.A.4
-
12
-
-
47849100622
-
The therapeutic effects of Rho-ROCK inhibitors on CNS disorders
-
Kubo T, Yamaguchi A, Iwata N, Yamashita T. 2008. The therapeutic effects of Rho-ROCK inhibitors on CNS disorders. Ther Clin Risk Manag 4(3):605-615.
-
(2008)
Ther Clin Risk Manag
, vol.4
, Issue.3
, pp. 605-615
-
-
Kubo, T.1
Yamaguchi, A.2
Iwata, N.3
Yamashita, T.4
-
13
-
-
0036788406
-
Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time
-
Kuhlmann T, Lingfeld G, Bitsch A, Schuchardt J, Bruck W. 2002. Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. Brain 125(Part 10):2202-2212.
-
(2002)
Brain
, vol.125
, Issue.PART 10
, pp. 2202-2212
-
-
Kuhlmann, T.1
Lingfeld, G.2
Bitsch, A.3
Schuchardt, J.4
Bruck, W.5
-
14
-
-
77955656367
-
Axonal and neuronal pathology in multiple sclerosis: What have we learnt from animal models
-
Lassmann H. 2010. Axonal and neuronal pathology in multiple sclerosis: What have we learnt from animal models. Exp Neurol 225(1):2-8.
-
(2010)
Exp Neurol
, vol.225
, Issue.1
, pp. 2-8
-
-
Lassmann, H.1
-
15
-
-
0034686434
-
Coupling of peripheral tolerance to endogenous interleukin 10 promotes effective modulation of myelin-activated T cells and ameliorates experimental allergic encephalomyelitis
-
Legge KL, Min B, Bell JJ, Caprio JC, Li L, Gregg RK, Zaghouani H. 2000. Coupling of peripheral tolerance to endogenous interleukin 10 promotes effective modulation of myelin-activated T cells and ameliorates experimental allergic encephalomyelitis. J Exp Med 191(12):2039-2052.
-
(2000)
J Exp Med
, vol.191
, Issue.12
, pp. 2039-2052
-
-
Legge, K.L.1
Min, B.2
Bell, J.J.3
Caprio, J.C.4
Li, L.5
Gregg, R.K.6
Zaghouani, H.7
-
16
-
-
78649542915
-
Endogenous estrogens, through estrogen receptor alpha, constrain autoimmune inflammation in female mice by limiting CD4(+) T-cell homing into the CNS
-
Lelu K, Delpy L, Robert V, Foulon E, Laffont S, Pelletier L, Engelhardt B, Guery JC. 2010. Endogenous estrogens, through estrogen receptor alpha, constrain autoimmune inflammation in female mice by limiting CD4(+) T-cell homing into the CNS. Eur J Immunol 40(12):3489-3498.
-
(2010)
Eur J Immunol
, vol.40
, Issue.12
, pp. 3489-3498
-
-
Lelu, K.1
Delpy, L.2
Robert, V.3
Foulon, E.4
Laffont, S.5
Pelletier, L.6
Engelhardt, B.7
Guery, J.C.8
-
17
-
-
33748372947
-
Activation of estrogen receptor-alpha reduces aortic smooth muscle differentiation
-
Montague CR, Hunter MG, Gavrilin MA, Phillips GS, Goldschmidt-Clermont PJ, Marsh CB. 2006. Activation of estrogen receptor-alpha reduces aortic smooth muscle differentiation. Circ Res 99(5):477-484.
-
(2006)
Circ Res
, vol.99
, Issue.5
, pp. 477-484
-
-
Montague, C.R.1
Hunter, M.G.2
Gavrilin, M.A.3
Phillips, G.S.4
Goldschmidt-Clermont, P.J.5
Marsh, C.B.6
-
18
-
-
79951721608
-
Estradiol induces endothelial cell migration and proliferation through estrogen receptor-enhanced RhoA/ROCK pathway
-
30;335
-
Oviedo PJ, Sobrino A, Laguna-Fernandez A, Novella S, Tarin JJ, Garcia-Perez MA, Sanchis J, Cano A, Hermenegildo C. 2011. Estradiol induces endothelial cell migration and proliferation through estrogen receptor-enhanced RhoA/ROCK pathway. Mol Cell Endocrinol 30;335(2):96-103.
-
(2011)
Mol Cell Endocrinol
, Issue.2
, pp. 96-103
-
-
Oviedo, P.J.1
Sobrino, A.2
Laguna-Fernandez, A.3
Novella, S.4
Tarin, J.J.5
Garcia-Perez, M.A.6
Sanchis, J.7
Cano, A.8
Hermenegildo, C.9
-
19
-
-
85081453944
-
-
The rat brain in stereotaxic coordinates. Academic Press, San Diego, CA.
-
Paxinos G, Watson C. 1986. The rat brain in stereotaxic coordinates. Academic Press, San Diego, CA.
-
(1986)
-
-
Paxinos, G.1
Watson, C.2
-
20
-
-
78650765469
-
Gonadotropin-releasing hormone reduces the severity of experimental autoimmune encephalomyelitis, a model of multiple sclerosis
-
Quintanar JL, Salinas E, Quintanar-Stephano A. 2011. Gonadotropin-releasing hormone reduces the severity of experimental autoimmune encephalomyelitis, a model of multiple sclerosis. Neuropeptides 45(1):43-48.
-
(2011)
Neuropeptides
, vol.45
, Issue.1
, pp. 43-48
-
-
Quintanar, J.L.1
Salinas, E.2
Quintanar-Stephano, A.3
-
21
-
-
34548772338
-
ROCK and Rho: Biochemistry and neuronal functions of Rho-associated protein kinases
-
Schmandke A, Strittmatter SM. 2007. ROCK and Rho: Biochemistry and neuronal functions of Rho-associated protein kinases. Neuroscientist 13(5):454-469.
-
(2007)
Neuroscientist
, vol.13
, Issue.5
, pp. 454-469
-
-
Schmandke, A.1
Strittmatter, S.M.2
-
22
-
-
79957723865
-
Neuroprotection mediated through estrogen receptor-alpha in astrocytes
-
Spence RD, Hamby ME, Umeda E, Itoh N, Du S, Wisdom AJ, Cao Y, Bondar G, Lam J, Ao Y, Sandoval F, Suriany S, Sofroniew MV, Voskuhl RR. 2011. Neuroprotection mediated through estrogen receptor-alpha in astrocytes. Proc Natl Acad Sci USA 108(21):8867-8872.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.21
, pp. 8867-8872
-
-
Spence, R.D.1
Hamby, M.E.2
Umeda, E.3
Itoh, N.4
Du, S.5
Wisdom, A.J.6
Cao, Y.7
Bondar, G.8
Lam, J.9
Ao, Y.10
Sandoval, F.11
Suriany, S.12
Sofroniew, M.V.13
Voskuhl, R.R.14
-
23
-
-
33750618507
-
The selective Rho-kinase inhibitor Fasudil is protective and therapeutic in experimental autoimmune encephalomyelitis
-
Sun X, Minohara M, Kikuchi H, Ishizu T, Tanaka M, Piao H, Osoegawa M, Ohyagi Y, Shimokawa H, Kira J. 2006. The selective Rho-kinase inhibitor Fasudil is protective and therapeutic in experimental autoimmune encephalomyelitis. J Neuroimmunol 180(1-2):126-134.
-
(2006)
J Neuroimmunol
, vol.180
, Issue.1-2
, pp. 126-134
-
-
Sun, X.1
Minohara, M.2
Kikuchi, H.3
Ishizu, T.4
Tanaka, M.5
Piao, H.6
Osoegawa, M.7
Ohyagi, Y.8
Shimokawa, H.9
Kira, J.10
-
24
-
-
84873987385
-
Minocycline promotes axonal regeneration through suppression of RGMa in rat MCAO/reperfusion model
-
Tao T, Xu G, Si Chen C, Feng J, Kong Y, Qin X. 2013. Minocycline promotes axonal regeneration through suppression of RGMa in rat MCAO/reperfusion model. Synapse 67(4):189-198.
-
(2013)
Synapse
, vol.67
, Issue.4
, pp. 189-198
-
-
Tao, T.1
Xu, G.2
Si Chen, C.3
Feng, J.4
Kong, Y.5
Qin, X.6
-
25
-
-
70349778705
-
Neuroprotective and anti-inflammatory effects of estrogen receptor ligand treatment in mice
-
Tiwari-Woodruff S, Voskuhl RR. 2009. Neuroprotective and anti-inflammatory effects of estrogen receptor ligand treatment in mice. J Neurol Sci 286(1-2):81-85.
-
(2009)
J Neurol Sci
, vol.286
, Issue.1-2
, pp. 81-85
-
-
Tiwari-Woodruff, S.1
Voskuhl, R.R.2
-
26
-
-
35548975206
-
Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)alpha and ERbeta ligand treatment
-
Tiwari-Woodruff S, Morales LB, Lee R, Voskuhl RR. 2007. Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)alpha and ERbeta ligand treatment. Proc Natl Acad Sci USA 104(37):14813-14818.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.37
, pp. 14813-14818
-
-
Tiwari-Woodruff, S.1
Morales, L.B.2
Lee, R.3
Voskuhl, R.R.4
-
27
-
-
35748966435
-
Anti-IL-17A autovaccination prevents clinical and histological manifestations of experimental autoimmune encephalomyelitis
-
Uyttenhove C, Sommereyns C, Theate I, Michiels T, Van Snick J. 2007. Anti-IL-17A autovaccination prevents clinical and histological manifestations of experimental autoimmune encephalomyelitis. Ann N Y Acad Sci 1110:330-336.
-
(2007)
Ann N Y Acad Sci
, vol.1110
, pp. 330-336
-
-
Uyttenhove, C.1
Sommereyns, C.2
Theate, I.3
Michiels, T.4
Van Snick, J.5
-
28
-
-
67349252320
-
17beta-estradiol attenuates vascular contraction through inhibition of RhoA/Rho kinase pathway
-
Yang E, Jeon SB, Baek I, Chen ZA, Jin Z, Kim IK. 2009. 17beta-estradiol attenuates vascular contraction through inhibition of RhoA/Rho kinase pathway. Naunyn Schmiedebergs Arch Pharmacol 380(1):35-44.
-
(2009)
Naunyn Schmiedebergs Arch Pharmacol
, vol.380
, Issue.1
, pp. 35-44
-
-
Yang, E.1
Jeon, S.B.2
Baek, I.3
Chen, Z.A.4
Jin, Z.5
Kim, I.K.6
-
29
-
-
77950953051
-
GPR30, but not estrogen receptor-alpha, is crucial in the treatment of experimental autoimmune encephalomyelitis by oral ethinyl estradiol
-
Yates MA, Li Y, Chlebeck PJ, Offner H. 2010. GPR30, but not estrogen receptor-alpha, is crucial in the treatment of experimental autoimmune encephalomyelitis by oral ethinyl estradiol. BMC Immunol 11:20.
-
(2010)
BMC Immunol
, vol.11
, pp. 20
-
-
Yates, M.A.1
Li, Y.2
Chlebeck, P.J.3
Offner, H.4
-
30
-
-
77952357821
-
Therapeutic potential of experimental autoimmune encephalomyelitis by Fasudil, a Rho kinase inhibitor
-
Yu JZ, Ding J, Ma CG, Sun CH, Sun YF, Lu CZ, Xiao BG. 2010. Therapeutic potential of experimental autoimmune encephalomyelitis by Fasudil, a Rho kinase inhibitor. J Neurosci Res 88(8):1664-1672.
-
(2010)
J Neurosci Res
, vol.88
, Issue.8
, pp. 1664-1672
-
-
Yu, J.Z.1
Ding, J.2
Ma, C.G.3
Sun, C.H.4
Sun, Y.F.5
Lu, C.Z.6
Xiao, B.G.7
|