-
1
-
-
0343983913
-
3-Nitropropionate, the toxic substance of indigofera, is a suicide inactivator of succinate dehydrogenase
-
Alston TA, Mela L, Bright HJ, (1977) 3-Nitropropionate, the toxic substance of indigofera, is a suicide inactivator of succinate dehydrogenase. Proc Natl Acad Sci USA 74: 3767-3771.
-
(1977)
Proc Natl Acad Sci USA
, vol.74
, pp. 3767-3771
-
-
Alston, T.A.1
Mela, L.2
Bright, H.J.3
-
2
-
-
0028894042
-
3-Nitropropionic acid induces apoptosis in cultured striatal and cortical neurons
-
Behrens M, Koh J, Canzoniero L, Sensi S, Csernansky C, et al. (1995) 3-Nitropropionic acid induces apoptosis in cultured striatal and cortical neurons. Neuroreport 6: 545-548.
-
(1995)
Neuroreport
, vol.6
, pp. 545-548
-
-
Behrens, M.1
Koh, J.2
Canzoniero, L.3
Sensi, S.4
Csernansky, C.5
-
3
-
-
0034597411
-
Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity
-
Leventhal L, Sortwell C, Hanbury R, Collier T, Kordower J, et al. (2000) Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity. J Comp Neurol 425: 471-478.
-
(2000)
J Comp Neurol
, vol.425
, pp. 471-478
-
-
Leventhal, L.1
Sortwell, C.2
Hanbury, R.3
Collier, T.4
Kordower, J.5
-
4
-
-
0027433553
-
Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
-
Beal M, Brouillet E, Jenkins B, Ferrante R, Kowall N, et al. (1993) Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. J Neurosci 13: 4181-4192.
-
(1993)
J Neurosci
, vol.13
, pp. 4181-4192
-
-
Beal, M.1
Brouillet, E.2
Jenkins, B.3
Ferrante, R.4
Kowall, N.5
-
5
-
-
29144468251
-
3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease
-
Brouillet E, Jacquard C, Bizat N, Blum D, (2005) 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease. J Neurochem 95: 1521-1540.
-
(2005)
J Neurochem
, vol.95
, pp. 1521-1540
-
-
Brouillet, E.1
Jacquard, C.2
Bizat, N.3
Blum, D.4
-
6
-
-
65249125897
-
p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum
-
Zhang X, Wang Y, Zhang X, Han R, Wu J, et al. (2009) p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum. Autophagy 5: 339-350.
-
(2009)
Autophagy
, vol.5
, pp. 339-350
-
-
Zhang, X.1
Wang, Y.2
Zhang, X.3
Han, R.4
Wu, J.5
-
7
-
-
0037131263
-
Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons
-
Goffredo D, Rigamonti D, Tartari M, De Micheli A, Verderio C, et al. (2002) Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons. J Biol Chem 277: 39594-39598.
-
(2002)
J Biol Chem
, vol.277
, pp. 39594-39598
-
-
Goffredo, D.1
Rigamonti, D.2
Tartari, M.3
De Micheli, A.4
Verderio, C.5
-
8
-
-
33745885329
-
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
-
Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, et al. (2006) DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 126: 121-134.
-
(2006)
Cell
, vol.126
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
Syed, N.4
Smith, P.5
-
9
-
-
4544385218
-
Autophagy: many paths to the same end
-
Cuervo A, (2004) Autophagy: many paths to the same end. Mol Cell Biochem 263: 55-72.
-
(2004)
Mol Cell Biochem
, vol.263
, pp. 55-72
-
-
Cuervo, A.1
-
10
-
-
14044277429
-
The molecular machinery of autophagy: unanswered questions
-
Klionsky DJ, (2005) The molecular machinery of autophagy: unanswered questions. J Cell Sci 118: 7-18.
-
(2005)
J Cell Sci
, vol.118
, pp. 7-18
-
-
Klionsky, D.J.1
-
11
-
-
34548093280
-
How shall I eat thee?
-
Klionsky D, Cuervo A, Dunn W, Levine B, van der Klei I, et al. (2007) How shall I eat thee? Autophagy 3: 413-416.
-
(2007)
Autophagy
, vol.3
, pp. 413-416
-
-
Klionsky, D.1
Cuervo, A.2
Dunn, W.3
Levine, B.4
van der Klei, I.5
-
12
-
-
36249025723
-
Autophagy: process and function
-
Mizushima N, (2007) Autophagy: process and function. Genes & Dev 21: 2861-2873.
-
(2007)
Genes & Dev
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
13
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
Rubinsztein D, (2006) The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 443: 780-786.
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.1
-
14
-
-
0014481739
-
Uptake of protein by mammalian neurons
-
Holtzman E, Peterson ER, (1969) Uptake of protein by mammalian neurons. J Cell Biol 40: 863-869.
-
(1969)
J Cell Biol
, vol.40
, pp. 863-869
-
-
Holtzman, E.1
Peterson, E.R.2
-
15
-
-
0026886919
-
Purification and characterization of (Ca2+-Mg2+)-ATPase in rat liver lysosomal membranes
-
Ezaki J, Himeno M, Kato K, (1992) Purification and characterization of (Ca2+-Mg2+)-ATPase in rat liver lysosomal membranes. J Biochem 112: 33-39.
-
(1992)
J Biochem
, vol.112
, pp. 33-39
-
-
Ezaki, J.1
Himeno, M.2
Kato, K.3
-
16
-
-
0023101580
-
Lysosomal cystine transport. Effect of intralysosomal pH and membrane potential
-
Smith M, Greene A, Potashnik R, Mendoza S, Schneider J, (1987) Lysosomal cystine transport. Effect of intralysosomal pH and membrane potential. J Biol Chem 262: 1244-1253.
-
(1987)
J Biol Chem
, vol.262
, pp. 1244-1253
-
-
Smith, M.1
Greene, A.2
Potashnik, R.3
Mendoza, S.4
Schneider, J.5
-
17
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky D, Abeliovich H, Agostinis P, Agrawal D, Aliev G, et al. (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4: 151-175.
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.4
Aliev, G.5
-
18
-
-
0035793580
-
Lysosomal protease pathways to apoptosis. Cleavage of Bid, not pro-caspases, is the most likely route
-
Stoka V, Turk B, Schendel SL, Kim T-H, Cirman T, et al. (2001) Lysosomal protease pathways to apoptosis. Cleavage of Bid, not pro-caspases, is the most likely route. J Biol Chem 276: 3149-3157.
-
(2001)
J Biol Chem
, vol.276
, pp. 3149-3157
-
-
Stoka, V.1
Turk, B.2
Schendel, S.L.3
Kim, T.-H.4
Cirman, T.5
-
19
-
-
38949112123
-
An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid
-
Wang Y, Han R, Liang Z, Wu J, Zhang X, et al. (2008) An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid. Autophagy 4: 214-226.
-
(2008)
Autophagy
, vol.4
, pp. 214-226
-
-
Wang, Y.1
Han, R.2
Liang, Z.3
Wu, J.4
Zhang, X.5
-
20
-
-
50249189191
-
Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways
-
Wen Y, Sheng R, Zhang L, Han R, Zhang X, et al. (2008) Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways. Autophagy 4: 762-769.
-
(2008)
Autophagy
, vol.4
, pp. 762-769
-
-
Wen, Y.1
Sheng, R.2
Zhang, L.3
Han, R.4
Zhang, X.5
-
21
-
-
33646364818
-
Activation of Bak and Bax through c-Abl-Protein Kinase C{delta}-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells
-
Choi S-Y, Kim M-J, Kang C-M, Bae S, Cho C-K, et al. (2006) Activation of Bak and Bax through c-Abl-Protein Kinase C{delta}-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells. J Biol Chem 281: 7049-7059.
-
(2006)
J Biol Chem
, vol.281
, pp. 7049-7059
-
-
Choi, S.-Y.1
Kim, M.-J.2
Kang, C.-M.3
Bae, S.4
Cho, C.-K.5
-
22
-
-
33745812349
-
Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation
-
Xin M, Deng X, (2006) Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation. J Biol Chem 281: 18859-18867.
-
(2006)
J Biol Chem
, vol.281
, pp. 18859-18867
-
-
Xin, M.1
Deng, X.2
-
23
-
-
0033561799
-
Nuclear factor kappa B nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum
-
Qin Z-H, Chen R-W, Wang Y, Nakai M, Chuang D-M, et al. (1999) Nuclear factor kappa B nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum. J Neurosci 19: 4023-4033.
-
(1999)
J Neurosci
, vol.19
, pp. 4023-4033
-
-
Qin, Z.-H.1
Chen, R.-W.2
Wang, Y.3
Nakai, M.4
Chuang, D.-M.5
-
24
-
-
2642714342
-
Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents
-
Ohkuma S, Poole B, (1978) Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents. Proc Natl Acad Sci USA 75: 3327-3331.
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, pp. 3327-3331
-
-
Ohkuma, S.1
Poole, B.2
-
25
-
-
0020511451
-
Acidification of macrophage and fibroblast endocytic vesicles in vitro
-
Galloway CJ, Dean GE, Marsh M, Rudnick G, Mellman I, (1983) Acidification of macrophage and fibroblast endocytic vesicles in vitro. Proc Natl Acad Sci USA 80: 3334-3338.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 3334-3338
-
-
Galloway, C.J.1
Dean, G.E.2
Marsh, M.3
Rudnick, G.4
Mellman, I.5
-
26
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, et al. (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19: 5720-5728.
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
-
27
-
-
27944504351
-
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
Bjorkoy G, Lamark T, Brech A, Outzen H, Perander M, et al. (2005) p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 171: 603-614.
-
(2005)
J Cell Biol
, vol.171
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
-
28
-
-
34249056243
-
p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death
-
Crighton D, O'Prey J, Bell H, Ryan K, (2007) p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death. Cell Death Differ 14: 1071-1079.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1071-1079
-
-
Crighton, D.1
O'Prey, J.2
Bell, H.3
Ryan, K.4
-
29
-
-
34548077575
-
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
-
Kimura S, Noda T, Yoshimori T, (2007) Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 3: 452-460.
-
(2007)
Autophagy
, vol.3
, pp. 452-460
-
-
Kimura, S.1
Noda, T.2
Yoshimori, T.3
-
30
-
-
0029165047
-
Chloride channels of intracellular organelles
-
al-Awqati Q, (1995) Chloride channels of intracellular organelles. Curr Opin Cell Biol 7: 504-508.
-
(1995)
Curr Opin Cell Biol
, vol.7
, pp. 504-508
-
-
al-Awqati, Q.1
-
31
-
-
19944434059
-
Inhibition of macroautophagy triggers apoptosis
-
Boya P, Gonzalez-Polo R-A, Casares N, Perfettini J-L, Dessen P, et al. (2005) Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol 25: 1025-1040.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1025-1040
-
-
Boya, P.1
Gonzalez-Polo, R.-A.2
Casares, N.3
Perfettini, J.-L.4
Dessen, P.5
-
32
-
-
0034892909
-
Therapeutic effects of cysteine protease inhibition in allergic lung inflammation: inhibition of allergen-specific T lymphocyte migration
-
Layton G, Harris S, Bland F, Lee S, Fearn S, et al. (2001) Therapeutic effects of cysteine protease inhibition in allergic lung inflammation: inhibition of allergen-specific T lymphocyte migration. Inflamm Res 50: 400-408.
-
(2001)
Inflamm Res
, vol.50
, pp. 400-408
-
-
Layton, G.1
Harris, S.2
Bland, F.3
Lee, S.4
Fearn, S.5
-
33
-
-
0036304614
-
Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid
-
Kim G, Chan P, (2002) Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid. J Cereb Blood Flow Metab 22: 798-809.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 798-809
-
-
Kim, G.1
Chan, P.2
-
34
-
-
84873740471
-
The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells
-
Galavotti S, Bartesaghi S, Faccenda D, Shaked-Rabi M, Sanzone S, et al. (2013) The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. Oncogene 32: 669-712.
-
(2013)
Oncogene
, vol.32
, pp. 669-712
-
-
Galavotti, S.1
Bartesaghi, S.2
Faccenda, D.3
Shaked-Rabi, M.4
Sanzone, S.5
-
35
-
-
0021040946
-
Lysosomes revisited
-
de Duve C, (1983) Lysosomes revisited. Eur J Biochem 137: 391-397.
-
(1983)
Eur J Biochem
, vol.137
, pp. 391-397
-
-
de Duve, C.1
-
36
-
-
0025925091
-
Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells
-
Yoshimori T, Yamamoto A, Moriyama Y, Futai M, Tashiro Y, (1991) Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. J Biol Chem 266: 17707-17712.
-
(1991)
J Biol Chem
, vol.266
, pp. 17707-17712
-
-
Yoshimori, T.1
Yamamoto, A.2
Moriyama, Y.3
Futai, M.4
Tashiro, Y.5
-
37
-
-
80555143078
-
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H+-ATPase
-
Zoncu R, Bar-Peled L, Efeyan A, Wang S, Sancak Y, et al. (2011) mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H+-ATPase. Science 334: 678-683.
-
(2011)
Science
, vol.334
, pp. 678-683
-
-
Zoncu, R.1
Bar-Peled, L.2
Efeyan, A.3
Wang, S.4
Sancak, Y.5
|