Loss of function of Ribonuclease T2, an ancient and phylogenetically conserved RNase, plays a crucial role in ovarian tumorigenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 20, 2013, Pages 8140-8145

  Acquati, Francesco ^a   Lualdi, Marta ^a   Bertilaccio, Sabrina ^b   Monti, Laura ^a   Turconi, Giovanna ^a   Fabbri, Marco ^c   Grimaldi, Annalisa ^a   Anselmo, Achille ^d   Inforzato, Antonio ^d   Collotta, Angelo ^c   Cimetti, Laura ^e   Riva, Cristina ^e   Gribaldo, Laura ^c   Ghia, Paolo ^b   Taramelli, Roberto ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c JOINT RESEARCH CENTRE   (Italy)

^d Clinical and Research Center Humanitas   (Italy)

^e OSPEDALE DI CIRCOLO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DICER; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RIBONUCLEASE; RIBONUCLEASE T2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CONTROL; CANCER GROWTH; CARCINOGENESIS; GENE EXPRESSION; GENE FUNCTION; IMMUNOMODULATION; IN VITRO STUDY; INNATE IMMUNITY; MACROPHAGE; MICROINJECTION; MOUSE; NONHUMAN; OVARY CARCINOGENESIS; PHYLOGENY; PRIORITY JOURNAL; STROMA CELL; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; CHEMOTAXIS; ENDORIBONUCLEASES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HUMANS; MACROPHAGES; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; OVARIAN NEOPLASMS; PHYLOGENY; POLYMERASE CHAIN REACTION; U937 CELLS;

EID: 84877842742     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222079110     Document Type: Article

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