The circadian Per1 and Per2 genes influence alcohol intake, reinforcement, and blood alcohol levels

Behavioural Brain Research

Volumn 249, Issue , 2013, Pages 15-21

  Gamsby, J J ^a,b   Templeton, E L ^a   Bonvini, L A ^a   Wang, W ^a   Loros, J J ^a   Dunlap, J C ^a   Green, A I ^a   Gulick, D ^a,b  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Addiction; Alcoholism; Clock; Genetics

Indexed keywords

ALCOHOL;

ADULT ANIMAL; ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; FEMALE; GENE MUTATION; MALE; MOUSE; NONHUMAN; PER1 GENE; PER2 GENE; PLACE PREFERENCE; PRIORITY JOURNAL; REINFORCEMENT; RIGHTING REFLEX;

ALCOHOL DRINKING; ANIMALS; ASSOCIATION LEARNING; CONDITIONING, OPERANT; ETHANOL; FEMALE; GENOTYPE; MALE; MICE; MICE, INBRED C57BL; MUTATION; PERIOD CIRCADIAN PROTEINS; REFLEX, RIGHTING; REINFORCEMENT (PSYCHOLOGY);

EID: 84877798002     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2013.04.016     Document Type: Article

References (34)

1. Falcon E., McClung C.A. A role for the circadian genes in drug addiction. Neuropharmacology 2009, 56(Suppl. 1):91-96.
2. Benca R.M., Obermeyer W.H., Thisted R.A., Gillin J.C. Sleep and psychiatric disorders. A meta-analysis. Archives of General Psychiatry 1992, 49:651-668. (discussion 669-670).
3. Kovanen L., Saarikoski S.T., Haukka J., Pirkola S., Aromaa A., Lonnqvist J., Partonen T. Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption. Alcohol and Alcoholism 2010, 45:303-311.
4. Perreau-Lenz S., Zghoul T., de Fonseca F.R., Spanagel R., Bilbao A. Circadian regulation of central ethanol sensitivity by the mPer2 gene. Addiction Biology 2009, 14:253-259.
5. Spanagel R., Pendyala G., Abarca C., Zghoul T., Sanchis-Segura C., Magnone M.C., Lascorz J., Depner M., Holzberg D., Soyka M., Schreiber S., Matsuda F., Lathrop M., Schumann G., Albrecht U. The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. Nature Medicine 2005, 11:35-42.
6. Wirz-Justice A., Haug H.J., Cajochen C. Disturbed circadian rest-activity cycles in schizophrenia patients: an effect of drugs?. Schizophrenia Bulletin 2001, 27:497-502.
7. Abarca C., Albrecht U., Spanagel R. Cocaine sensitization and reward are under the influence of circadian genes and rhythm. Proceedings of the National Academy of Sciences of the United States of America 2002, 99:9026-9030.
8. Hampp G., Albrecht U. The circadian clock and mood-related behavior. Communicative & Integrative Biology 2008, 1:1-3.
9. Perreau-Lenz S., Vengeliene V., Noori H.R., Merlo-Pich E.V., Corsi M.A., Corti C., Spanagel R Inhibition of the casein-kinase-1-epsilon/delta prevents relapse-like alcohol drinking. Neuropsychopharmacology 2012, 37:2121-2131.
10. Crum R.M., Ford D.E., Storr C.L., Chan Y.F. Association of sleep disturbance with chronicity and remission of alcohol dependence: data from a population-based prospective study. Alcoholism, Clinical and Experimental Research 2004, 28:1533-1540.
11. Dong L., Bilbao A., Laucht M., Henriksson R., Yakovleva T., Ridinger M., Desrivieres S., Clarke T.K., Lourdusamy A., Smolka M.N., Cichon S., Blomeyer D., Treutlein J., Perreau-Lenz S., Witt S., Leonardi-Essmann F., Wodarz N., Zill P., Soyka M., Albrecht U., Rietschel M., Lathrop M., Bakalkin G., Spanagel R., Schumann G. Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking. American Journal of Psychiatry 2011, 168:1090-1098.
12. Wang X., Mozhui K., Li Z., Mulligan M.K., Ingels J.F., Zhou X., Hori R.T., Chen H., Cook M.N., Williams R.W., Lu L. A promoter polymorphism in the Per3 gene is associated with alcohol and stress response. Translational Psychiatry 2012, 2:e73.
13. Zghoul T., Abarca C., Sanchis-Segura C., Albrecht U., Schumann G., Spanagel R. Ethanol self-administration and reinstatement of ethanol-seeking behavior in Per1(Brdm1) mutant mice. Psychopharmacology 2007, 190:13-19.
14. McCulley W.D., Ascheid S., Crabbe J.C., Rosenwasser AM Selective breeding for ethanol-related traits alters circadian phenotype. Alcohol 2013, 47:187-194.
15. Trujillo J.L., Do D.T., Grahame N.J., Roberts A.J., Gorman M.R. Ethanol consumption in mice: relationships with circadian period and entrainment. Alcohol 2011, 45:147-159.
16. Cermakian N., Monaco L., Pando M.P., Dierich A., Sassone-Corsi P. Altered behavioral rhythms and clock gene expression in mice with a targeted mutation in the Period1 gene. EMBO Journal 2001, 20:3967-3974.
17. Zheng B., Larkin D.W., Albrecht U., Sun Z.S., Sage M., Eichele G., Lee C.C., Bradley A. The mPer2 gene encodes a functional component of the mammalian circadian clock. Nature 1999, 400:169-173.
18. Zheng B., Albrecht U., Kaasik K., Sage M., Lu W., Vaishnav S., Li Q., Sun Z.S., Eichele G., Bradley A., Lee C.C. Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell 2001, 105:683-694.
19. Gillin J.C. Sleep and psychoactive drugs of abuse and dependence. Principles and Practice of Sleep Medicine 1994, 934-942. W.B. Saunders, Philadelphia. M.H. Kryger (Ed.).
20. Danel T., Libersa C., Touitou Y. The effect of alcohol consumption on the circadian control of human core body temperature is time dependent. American Journal of Physiology-Regulatory Integrative and Comparative Physiology 2001, 281:R52-R55.
21. Yoneyama N., Crabbe J.C., Ford M.M., Murillo A., Finn D.A. Voluntary ethanol consumption in 22 inbred mouse strains. Alcohol 2008, 42:149-160.
22. Eriksson K., Pikkarainen P.H. Differences between the sexes in voluntary alcohol consumption and liver ADH-activity in inbred strains of mice. Metabolism: Clinical and Experimental 1968, 17:1037-1042.
23. Meliska C.J., Bartke A., McGlacken G., Jensen R.A. Ethanol, nicotine, amphetamine, and aspartame consumption and preferences in C57BL/6 and DBA/2 mice. Pharmacology, Biochemistry, and Behavior 1995, 50:619-626.
24. Middaugh L.D., Kelley B.M., Bandy A.L., McGroarty K.K. Ethanol consumption by C57BL/6 mice: influence of gender and procedural variables. Alcohol 1999, 17:175-183.
25. Comasco E., Nordquist N., Gokturk C., Aslund C., Hallman J., Oreland L., Nilsson K.W. The clock gene PER2 and sleep problems: association with alcohol consumption among Swedish adolescents. Upsala Journal of Medical Sciences 2010, 115:41-48.
26. Brager A.J., Prosser R.A., Glass J.D. Circadian and acamprosate modulation of elevated ethanol drinking in mPer2 clock gene mutant mice. Chronobiology International 2011, 28:664-672.
27. Shiromani P.J., Xu M., Winston E.M., Shiromani S.N., Gerashchenko D., Weaver D.R. Sleep rhythmicity and homeostasis in mice with targeted disruption of mPeriod genes. American Journal of Physiology-Regulatory Integrative and Comparative Physiology 2004, 287:R47-R57.
28. Green A.S., Grahame N.J. Ethanol drinking in rodents: is free-choice drinking related to the reinforcing effects of ethanol?. Alcohol 2008, 42:1-11.
29. Perreau-Lenz S., Spanagel R. The effects of drugs of abuse on clock genes. Drug News Perspect 2008, 21:211-217.
30. Hwa L.S., Chu A., Levinson S.A., Kayyali T.M., DeBold J.F., Miczek K.A. Persistent escalation of alcohol drinking in C57BL/6 J mice with intermittent access to 20% ethanol. Alcoholism, Clinical and Experimental Research 2011, 35:1938-1947.
31. Gater R., Tansella M., Korten A., Tiemens B.G., Mavreas V.G., Olatawura M.O. Sex differences in the prevalence and detection of depressive and anxiety disorders in general health care settings: report from the World Health Organization Collaborative Study on Psychological Problems in General Health Care. Archives of General Psychiatry 1998, 55:405-413.
32. Adamec R., Head D., Blundell J., Burton P., Berton O. Lasting anxiogenic effects of feline predator stress in mice: sex differences in vulnerability to stress and predicting severity of anxiogenic response from the stress experience. Physiology & Behavior 2006, 88:12-29.
33. Hampp G., Ripperger J.A., Houben T., Schmutz I., Blex C., Perreau-Lenz S., Brunk I., Spanagel R., Ahnert-Hilger G., Meijer J.H., Albrecht U. Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Current Biology 2008, 18:678-683.
34. Agapito M., Mian N., Boyadjieva N.I. Sarkar DK Period 2 gene deletion abolishes beta-endorphin neuronal response to ethanol. Alcoholism, Clinical and Experimental Research 2013, 34:1613-1618.