-
1
-
-
33947223664
-
Prospect of targeting the CD40 pathway for cancer therapy
-
17317815 10.1158/1078-0432.CCR-06-1893 1:CAS:528:DC%2BD2sXhvF2hs7c%3D
-
Vonderheide RH (2007) Prospect of targeting the CD40 pathway for cancer therapy. Clin Cancer Res 13(4):1083-1088
-
(2007)
Clin Cancer Res
, vol.13
, Issue.4
, pp. 1083-1088
-
-
Vonderheide, R.H.1
-
2
-
-
0031944607
-
CD40 and CD154 in cell-mediated immunity
-
9597126 10.1146/annurev.immunol.16.1.111 1:CAS:528:DyaK1cXislyitLg%3D
-
Grewal IS, Flavell RA (1998) CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 16:111-135
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 111-135
-
-
Grewal, I.S.1
Flavell, R.A.2
-
4
-
-
0032482274
-
Immunology. Licence to kill
-
9623994 10.1038/30845 1:CAS:528:DyaK1cXjs1Kisrk%3D
-
Lanzavecchia A (1998) Immunology. Licence to kill. Nature 393(6684):413-414
-
(1998)
Nature
, vol.393
, Issue.6684
, pp. 413-414
-
-
Lanzavecchia, A.1
-
5
-
-
0026528181
-
Molecular and biological characterization of a murine ligand for CD40
-
1374165 10.1038/357080a0 1:CAS:528:DyaK3sXitFSqsrY%3D
-
Armitage RJ, Fanslow WC, Strockbine L, Sato TA, Clifford KN, Macduff BM, Anderson DM, Gimpel SD, Davis-Smith T, Maliszewski CR et al (1992) Molecular and biological characterization of a murine ligand for CD40. Nature 357:80-82
-
(1992)
Nature
, vol.357
, pp. 80-82
-
-
Armitage, R.J.1
Fanslow, W.C.2
Strockbine, L.3
Sato, T.A.4
Clifford, K.N.5
MacDuff, B.M.6
Anderson, D.M.7
Gimpel, S.D.8
Davis-Smith, T.9
Maliszewski, C.R.10
-
6
-
-
2542476167
-
CD40/CD154 interactions at the interface of tolerance and immunity
-
15032580 10.1146/annurev.immunol.22.012703.104533 1:CAS:528: DC%2BD2cXktlOgs7g%3D
-
Quezada SA, Jarvinen LZ, Lind EF, Noelle RJ (2004) CD40/CD154 interactions at the interface of tolerance and immunity. Annu Rev Immunol 22:307-328
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 307-328
-
-
Quezada, S.A.1
Jarvinen, L.Z.2
Lind, E.F.3
Noelle, R.J.4
-
7
-
-
0032482356
-
Help for cytotoxic-T-cell responses is mediated by CD40 signalling
-
9624004 10.1038/30996 1:CAS:528:DyaK1cXjs1Kmtro%3D
-
Bennett SR, Carbone FR, Karamalis F, Flavell RA, Miller JF, Heath WR (1998) Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature 393(6684):478-480
-
(1998)
Nature
, vol.393
, Issue.6684
, pp. 478-480
-
-
Bennett, S.R.1
Carbone, F.R.2
Karamalis, F.3
Flavell, R.A.4
Miller, J.F.5
Heath, W.R.6
-
8
-
-
0032482337
-
A conditioned dendritic cell can be a temporal bridge between a CD4 + T-helper and a T-killer cell
-
9624003 10.1038/30989 1:CAS:528:DyaK1cXjs1Kms7s%3D
-
Ridge JP, Di Rosa F, Matzinger P (1998) A conditioned dendritic cell can be a temporal bridge between a CD4 + T-helper and a T-killer cell. Nature 393(6684):474-478
-
(1998)
Nature
, vol.393
, Issue.6684
, pp. 474-478
-
-
Ridge, J.P.1
Di Rosa, F.2
Matzinger, P.3
-
9
-
-
0032482474
-
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
-
9624005 10.1038/31002 1:CAS:528:DyaK1cXjs1Kmtbw%3D
-
Schoenberger SP, Toes RE, van der Voort EI, Offringa R, Melief CJ (1998) T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 393(6684):480-483
-
(1998)
Nature
, vol.393
, Issue.6684
, pp. 480-483
-
-
Schoenberger, S.P.1
Toes, R.E.2
Van Der Voort, E.I.3
Offringa, R.4
Melief, C.J.5
-
10
-
-
0032896709
-
CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help
-
10229232 10.1038/8426 1:CAS:528:DyaK1MXivVKrs7g%3D
-
French RR, Chan HT, Tutt AL, Glennie MJ (1999) CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help. Nat Med 5(5):548-553
-
(1999)
Nat Med
, vol.5
, Issue.5
, pp. 548-553
-
-
French, R.R.1
Chan, H.T.2
Tutt, A.L.3
Glennie, M.J.4
-
11
-
-
0032984496
-
CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy
-
10395322 10.1038/10495 1:CAS:528:DyaK1MXksVCrs78%3D
-
Diehl L, den Boer AT, Schoenberger SP, van der Voort EI, Schumacher TN, Melief CJ, Offringa R, Toes RE (1999) CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy. Nat Med 5(7):774-779
-
(1999)
Nat Med
, vol.5
, Issue.7
, pp. 774-779
-
-
Diehl, L.1
Den Boer, A.T.2
Schoenberger, S.P.3
Van Der Voort, E.I.4
Schumacher, T.N.5
Melief, C.J.6
Offringa, R.7
Toes, R.E.8
-
12
-
-
0032984347
-
Conversion of tumor-specific CD4 + T-cell tolerance to T-cell priming through in vivo ligation of CD40
-
10395323 10.1038/10503 1:CAS:528:DyaK1MXksVCrs7w%3D
-
Sotomayor EM, Borrello I, Tubb E, Rattis FM, Bien H, Lu Z, Fein S, Schoenberger S, Levitsky HI (1999) Conversion of tumor-specific CD4 + T-cell tolerance to T-cell priming through in vivo ligation of CD40. Nat Med 5(7):780-787
-
(1999)
Nat Med
, vol.5
, Issue.7
, pp. 780-787
-
-
Sotomayor, E.M.1
Borrello, I.2
Tubb, E.3
Rattis, F.M.4
Bien, H.5
Lu, Z.6
Fein, S.7
Schoenberger, S.8
Levitsky, H.I.9
-
13
-
-
0042591416
-
Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors
-
12907622 1:CAS:528:DC%2BD3sXmtFersrY%3D
-
Nowak AK, Robinson BW, Lake RA (2003) Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors. Cancer Res 63(15):4490-4496
-
(2003)
Cancer Res
, vol.63
, Issue.15
, pp. 4490-4496
-
-
Nowak, A.K.1
Robinson, B.W.2
Lake, R.A.3
-
14
-
-
1642362512
-
Combined TLR and CD40 triggering induces potent CD8 + T cell expansion with variable dependence on type i IFN
-
15007094 10.1084/jem.20031591 1:CAS:528:DC%2BD2cXisVaguro%3D
-
Ahonen CL, Doxsee CL, McGurran SM, Riter TR, Wade WF, Barth RJ, Vasilakos JP, Noelle RJ, Kedl RM (2004) Combined TLR and CD40 triggering induces potent CD8 + T cell expansion with variable dependence on type I IFN. J Exp Med 199(6):775-784
-
(2004)
J Exp Med
, vol.199
, Issue.6
, pp. 775-784
-
-
Ahonen, C.L.1
Doxsee, C.L.2
McGurran, S.M.3
Riter, T.R.4
Wade, W.F.5
Barth, R.J.6
Vasilakos, J.P.7
Noelle, R.J.8
Kedl, R.M.9
-
15
-
-
0034900413
-
Growth-inhibitory effects of CD40 ligand (CD154) and its endogenous expression in human breast cancer
-
11297266 1:CAS:528:DC%2BD3MXjtVOnsr8%3D
-
Tong AW, Papayoti MH, Netto G, Armstrong DT, Ordonez G, Lawson JM, Stone MJ (2001) Growth-inhibitory effects of CD40 ligand (CD154) and its endogenous expression in human breast cancer. Clin Cancer Res 7(3):691-703
-
(2001)
Clin Cancer Res
, vol.7
, Issue.3
, pp. 691-703
-
-
Tong, A.W.1
Papayoti, M.H.2
Netto, G.3
Armstrong, D.T.4
Ordonez, G.5
Lawson, J.M.6
Stone, M.J.7
-
16
-
-
33744987907
-
Eradication of established tumors in mice by a combination antibody-based therapy
-
16680149 10.1038/nm1405 1:CAS:528:DC%2BD28XltlOjsb4%3D
-
Uno T, Takeda K, Kojima Y, Yoshizawa H, Akiba H, Mittler RS, Gejyo F, Okumura K, Yagita H, Smyth MJ (2006) Eradication of established tumors in mice by a combination antibody-based therapy. Nat Med 12(6):693-698
-
(2006)
Nat Med
, vol.12
, Issue.6
, pp. 693-698
-
-
Uno, T.1
Takeda, K.2
Kojima, Y.3
Yoshizawa, H.4
Akiba, H.5
Mittler, R.S.6
Gejyo, F.7
Okumura, K.8
Yagita, H.9
Smyth, M.J.10
-
17
-
-
42449147062
-
Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines
-
18202224 10.1182/blood-2007-09-114371 1:CAS:528:DC%2BD1cXjvVamtb4%3D
-
Ahonen CL, Wasiuk A, Fuse S, Turk MJ, Ernstoff MS, Suriawinata AA, Gorham JD, Kedl RM, Usherwood EJ, Noelle RJ (2008) Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines. Blood 111(6):3116-3125
-
(2008)
Blood
, vol.111
, Issue.6
, pp. 3116-3125
-
-
Ahonen, C.L.1
Wasiuk, A.2
Fuse, S.3
Turk, M.J.4
Ernstoff, M.S.5
Suriawinata, A.A.6
Gorham, J.D.7
Kedl, R.M.8
Usherwood, E.J.9
Noelle, R.J.10
-
18
-
-
84874845333
-
Agonistic CD40 antibodies and cancer therapy
-
23460534 10.1158/1078-0432.CCR-12-2064 1:CAS:528:DC%2BC3sXjsFektrg%3D
-
Vonderheide RH, Glennie MJ (2013) Agonistic CD40 antibodies and cancer therapy. Clin Cancer Res 19(5):1035-1043
-
(2013)
Clin Cancer Res
, vol.19
, Issue.5
, pp. 1035-1043
-
-
Vonderheide, R.H.1
Glennie, M.J.2
-
19
-
-
79959746703
-
The CD40 agonist antibody CP-870,893 enhances dendritic cell and B-cell activity and promotes anti-tumor efficacy in SCID-hu mice
-
21479995 10.1007/s00262-011-1014-6 1:CAS:528:DC%2BC3MXnslOrs7g%3D
-
Gladue RP, Paradis T, Cole SH, Donovan C, Nelson R, Alpert R, Gardner J, Natoli E, Elliott E, Shepard R, Bedian V (2011) The CD40 agonist antibody CP-870,893 enhances dendritic cell and B-cell activity and promotes anti-tumor efficacy in SCID-hu mice. Cancer Immunol Immunother 60(7):1009-1017
-
(2011)
Cancer Immunol Immunother
, vol.60
, Issue.7
, pp. 1009-1017
-
-
Gladue, R.P.1
Paradis, T.2
Cole, S.H.3
Donovan, C.4
Nelson, R.5
Alpert, R.6
Gardner, J.7
Natoli, E.8
Elliott, E.9
Shepard, R.10
Bedian, V.11
-
20
-
-
70749083844
-
Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation
-
19906293 10.1186/1479-5876-7-93
-
Carpenter EL, Mick R, Ruter J, Vonderheide RH (2009) Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation. J Transl Med 7:93
-
(2009)
J Transl Med
, vol.7
, pp. 93
-
-
Carpenter, E.L.1
Mick, R.2
Ruter, J.3
Vonderheide, R.H.4
-
21
-
-
34247327043
-
An agonist antibody specific for CD40 induces dendritic cell maturation and promotes autologous anti-tumour T-cell responses in an in vitro mixed autologous tumour cell/lymph node cell model
-
17444959 10.1111/j.1365-3083.2007.01927.x 1:CAS:528:DC%2BD2sXmsF2lsrk%3D
-
Hunter TB, Alsarraj M, Gladue RP, Bedian V, Antonia SJ (2007) An agonist antibody specific for CD40 induces dendritic cell maturation and promotes autologous anti-tumour T-cell responses in an in vitro mixed autologous tumour cell/lymph node cell model. Scand J Immunol 65(5):479-486
-
(2007)
Scand J Immunol
, vol.65
, Issue.5
, pp. 479-486
-
-
Hunter, T.B.1
Alsarraj, M.2
Gladue, R.P.3
Bedian, V.4
Antonia, S.J.5
-
22
-
-
33947506186
-
Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody
-
17327609 10.1200/JCO.2006.08.3311 1:CAS:528:DC%2BD2sXjvVKmtLk%3D
-
Vonderheide RH, Flaherty KT, Khalil M, Stumacher MS, Bajor DL, Hutnick NA, Sullivan P, Mahany JJ, Gallagher M, Kramer A, Green SJ, O'Dwyer PJ, Running KL, Huhn RD, Antonia SJ (2007) Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody. J Clin Oncol 25(7):876-883
-
(2007)
J Clin Oncol
, vol.25
, Issue.7
, pp. 876-883
-
-
Vonderheide, R.H.1
Flaherty, K.T.2
Khalil, M.3
Stumacher, M.S.4
Bajor, D.L.5
Hutnick, N.A.6
Sullivan, P.7
Mahany, J.J.8
Gallagher, M.9
Kramer, A.10
Green, S.J.11
O'Dwyer, P.J.12
Running, K.L.13
Huhn, R.D.14
Antonia, S.J.15
-
23
-
-
78549256115
-
Immune modulation with weekly dosing of an agonist CD40 antibody in a phase i study of patients with advanced solid tumors
-
20855968 10.4161/cbt.10.10.13251 1:CAS:528:DC%2BC3MXit1ehu7c%3D
-
Ruter J, Antonia SJ, Burris HA 3rd, Huhn RD, Vonderheide RH (2010) Immune modulation with weekly dosing of an agonist CD40 antibody in a phase I study of patients with advanced solid tumors. Cancer Biol Ther 10(10):983-993
-
(2010)
Cancer Biol Ther
, vol.10
, Issue.10
, pp. 983-993
-
-
Ruter, J.1
Antonia, S.J.2
Burris III, H.A.3
Huhn, R.D.4
Vonderheide, R.H.5
-
24
-
-
79953154967
-
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans
-
21436454 10.1126/science.1198443 1:CAS:528:DC%2BC3MXjs1CgtLY%3D
-
Beatty GL, Chiorean EG, Fishman MP, Saboury B, Teitelbaum UR, Sun W, Huhn RD, Song W, Li D, Sharp LL, Torigian DA, O'Dwyer PJ, Vonderheide RH (2011) CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans. Science 331(6024):1612-1616
-
(2011)
Science
, vol.331
, Issue.6024
, pp. 1612-1616
-
-
Beatty, G.L.1
Chiorean, E.G.2
Fishman, M.P.3
Saboury, B.4
Teitelbaum, U.R.5
Sun, W.6
Huhn, R.D.7
Song, W.8
Li, D.9
Sharp, L.L.10
Torigian, D.A.11
O'Dwyer, P.J.12
Vonderheide, R.H.13
-
25
-
-
84877805593
-
Phase i study of CD40 antibody CP-870,893 in combination with carboplatin and paclitaxel in patients with advanced solid tumors
-
Vonderheide RH, Burg JM, Mick R, Trosko JA, Li D, Shaik MN, Tolcher AW, Hamid O (2013) Phase I study of CD40 antibody CP-870,893 in combination with carboplatin and paclitaxel in patients with advanced solid tumors. OncoImmunology 2(1):e23033
-
(2013)
OncoImmunology
, vol.2
, Issue.1
-
-
Vonderheide, R.H.1
Burg, J.M.2
Mick, R.3
Trosko, J.A.4
Li, D.5
Shaik, M.N.6
Tolcher, A.W.7
Hamid, O.8
-
26
-
-
33750533981
-
Giving blood: A new role for CD40 in tumorigenesis
-
17043147 10.1084/jem.20061754 1:CAS:528:DC%2BD28XhtFGqt7fK
-
Bergmann S, Pandolfi PP (2006) Giving blood: a new role for CD40 in tumorigenesis. J Exp Med 203(11):2409-2412
-
(2006)
J Exp Med
, vol.203
, Issue.11
, pp. 2409-2412
-
-
Bergmann, S.1
Pandolfi, P.P.2
-
27
-
-
70349334508
-
Phase i study of the humanized anti-CD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's lymphoma
-
19636010 10.1200/JCO.2008.21.3017 1:CAS:528:DC%2BD1MXht1WisbnN
-
Advani R, Forero-Torres A, Furman RR, Rosenblatt JD, Younes A, Ren H, Harrop K, Whiting N, Drachman JG (2009) Phase I study of the humanized anti-CD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's lymphoma. J Clin Oncol 27(26):4371-4377
-
(2009)
J Clin Oncol
, vol.27
, Issue.26
, pp. 4371-4377
-
-
Advani, R.1
Forero-Torres, A.2
Furman, R.R.3
Rosenblatt, J.D.4
Younes, A.5
Ren, H.6
Harrop, K.7
Whiting, N.8
Drachman, J.G.9
-
28
-
-
79954579274
-
Local activation of CD8 T cells and systemic tumor eradication without toxicity via slow release and local delivery of agonistic CD40 antibody
-
21389097 10.1158/1078-0432.CCR-10-2888 1:CAS:528:DC%2BC3MXkslCgsbs%3D
-
Fransen MF, Sluijter M, Morreau H, Arens R, Melief CJ (2011) Local activation of CD8 T cells and systemic tumor eradication without toxicity via slow release and local delivery of agonistic CD40 antibody. Clin Cancer Res 17(8):2270-2280
-
(2011)
Clin Cancer Res
, vol.17
, Issue.8
, pp. 2270-2280
-
-
Fransen, M.F.1
Sluijter, M.2
Morreau, H.3
Arens, R.4
Melief, C.J.5
-
29
-
-
0035152718
-
Novel allogeneic granulocyte-macrophage colony-stimulating factor-secreting tumor vaccine for pancreatic cancer: A phase i trial of safety and immune activation
-
11134207 1:CAS:528:DC%2BD3MXot1WgtQ%3D%3D
-
Jaffee EM, Hruban RH, Biedrzycki B, Laheru D, Schepers K, Sauter PR, Goemann M, Coleman J, Grochow L, Donehower RC, Lillemoe KD, O'Reilly S, Abrams RA, Pardoll DM, Cameron JL, Yeo CJ (2001) Novel allogeneic granulocyte- macrophage colony-stimulating factor-secreting tumor vaccine for pancreatic cancer: a phase I trial of safety and immune activation. J Clin Oncol 19(1):145-156
-
(2001)
J Clin Oncol
, vol.19
, Issue.1
, pp. 145-156
-
-
Jaffee, E.M.1
Hruban, R.H.2
Biedrzycki, B.3
Laheru, D.4
Schepers, K.5
Sauter, P.R.6
Goemann, M.7
Coleman, J.8
Grochow, L.9
Donehower, R.C.10
Lillemoe, K.D.11
O'Reilly, S.12
Abrams, R.A.13
Pardoll, D.M.14
Cameron, J.L.15
Yeo, C.J.16
-
30
-
-
79151486551
-
A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activation
-
21217520 10.1097/SLA.0b013e3181fd271c
-
Lutz E, Yeo CJ, Lillemoe KD, Biedrzycki B, Kobrin B, Herman J, Sugar E, Piantadosi S, Cameron JL, Solt S, Onners B, Tartakovsky I, Choi M, Sharma R, Illei PB, Hruban RH, Abrams RA, Le D, Jaffee E, Laheru D (2011) A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activation. Ann Surg 253(2):328-335
-
(2011)
Ann Surg
, vol.253
, Issue.2
, pp. 328-335
-
-
Lutz, E.1
Yeo, C.J.2
Lillemoe, K.D.3
Biedrzycki, B.4
Kobrin, B.5
Herman, J.6
Sugar, E.7
Piantadosi, S.8
Cameron, J.L.9
Solt, S.10
Onners, B.11
Tartakovsky, I.12
Choi, M.13
Sharma, R.14
Illei, P.B.15
Hruban, R.H.16
Abrams, R.A.17
Le, D.18
Jaffee, E.19
Laheru, D.20
more..
-
31
-
-
84872098740
-
Advances in therapeutic vaccines for pancreatic cancer
-
22935205
-
Plate JM (2012) Advances in therapeutic vaccines for pancreatic cancer. Discov Med 14(75):89-95
-
(2012)
Discov Med
, vol.14
, Issue.75
, pp. 89-95
-
-
Plate, J.M.1
-
32
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
-
9196156 1:CAS:528:DyaK2sXlsFKksLY%3D
-
Burris HA 3rd, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P, Nelson R, Dorr FA, Stephens CD, Von Hoff DD (1997) Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 15(6):2403-2413
-
(1997)
J Clin Oncol
, vol.15
, Issue.6
, pp. 2403-2413
-
-
Burris III, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Modiano, M.R.6
Cripps, M.C.7
Portenoy, R.K.8
Storniolo, A.M.9
Tarassoff, P.10
Nelson, R.11
Dorr, F.A.12
Stephens, C.D.13
Von Hoff, D.D.14
-
33
-
-
19344362405
-
Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
-
15894267 10.1016/j.ccr.2005.04.023 1:CAS:528:DC%2BD2MXkslyitLk%3D
-
Hingorani SR, Wang L, Multani AS, Combs C, Deramaudt TB, Hruban RH, Rustgi AK, Chang S, Tuveson DA (2005) Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 7(5):469-483
-
(2005)
Cancer Cell
, vol.7
, Issue.5
, pp. 469-483
-
-
Hingorani, S.R.1
Wang, L.2
Multani, A.S.3
Combs, C.4
Deramaudt, T.B.5
Hruban, R.H.6
Rustgi, A.K.7
Chang, S.8
Tuveson, D.A.9
-
34
-
-
67349181841
-
Immunosurveillance of pancreatic adenocarcinoma: Insights from genetically engineered mouse models of cancer
-
19013709 10.1016/j.canlet.2008.09.037 1:CAS:528:DC%2BD1MXltlejtrw%3D
-
Clark CE, Beatty GL, Vonderheide RH (2009) Immunosurveillance of pancreatic adenocarcinoma: insights from genetically engineered mouse models of cancer. Cancer Lett 279(1):1-7
-
(2009)
Cancer Lett
, vol.279
, Issue.1
, pp. 1-7
-
-
Clark, C.E.1
Beatty, G.L.2
Vonderheide, R.H.3
-
35
-
-
35148814410
-
Dynamics of the immune reaction to pancreatic cancer from inception to invasion
-
17909062 10.1158/0008-5472.CAN-07-0175 1:CAS:528:DC%2BD2sXhtFSnurvF
-
Clark CE, Hingorani SR, Mick R, Combs C, Tuveson DA, Vonderheide RH (2007) Dynamics of the immune reaction to pancreatic cancer from inception to invasion. Cancer Res 67(19):9518-9527
-
(2007)
Cancer Res
, vol.67
, Issue.19
, pp. 9518-9527
-
-
Clark, C.E.1
Hingorani, S.R.2
Mick, R.3
Combs, C.4
Tuveson, D.A.5
Vonderheide, R.H.6
-
36
-
-
18644379552
-
CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitro
-
15879094 1:CAS:528:DC%2BD2MXjvV2mtr4%3D
-
Buhtoiarov IN, Lum H, Berke G, Paulnock DM, Sondel PM, Rakhmilevich AL (2005) CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitro. J Immunol 174(10):6013-6022
-
(2005)
J Immunol
, vol.174
, Issue.10
, pp. 6013-6022
-
-
Buhtoiarov, I.N.1
Lum, H.2
Berke, G.3
Paulnock, D.M.4
Sondel, P.M.5
Rakhmilevich, A.L.6
-
37
-
-
44249125542
-
CD40 ligation in vivo can induce T cell independent antitumor effects even against immunogenic tumors
-
18214476 10.1007/s00262-007-0447-4
-
Rakhmilevich AL, Buhtoiarov IN, Malkovsky M, Sondel PM (2008) CD40 ligation in vivo can induce T cell independent antitumor effects even against immunogenic tumors. Cancer Immunol Immunother 57(8):1151-1160
-
(2008)
Cancer Immunol Immunother
, vol.57
, Issue.8
, pp. 1151-1160
-
-
Rakhmilevich, A.L.1
Buhtoiarov, I.N.2
Malkovsky, M.3
Sondel, P.M.4
-
38
-
-
84870288924
-
Cancer immunoediting by the innate immune system in the absence of adaptive immunity
-
22927549 10.1084/jem.20112738
-
O'Sullivan T, Saddawi-Konefka R, Vermi W, Koebel CM, Arthur C, White JM, Uppaluri R, Andrews DM, Ngiow SF, Teng MW, Smyth MJ, Schreiber RD, Bui JD (2012) Cancer immunoediting by the innate immune system in the absence of adaptive immunity. J Exp Med 209(10):1869-1882
-
(2012)
J Exp Med
, vol.209
, Issue.10
, pp. 1869-1882
-
-
O'Sullivan, T.1
Saddawi-Konefka, R.2
Vermi, W.3
Koebel, C.M.4
Arthur, C.5
White, J.M.6
Uppaluri, R.7
Andrews, D.M.8
Ngiow, S.F.9
Teng, M.W.10
Smyth, M.J.11
Schreiber, R.D.12
Bui, J.D.13
-
39
-
-
79960411324
-
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
-
21654748 10.1038/nature10138 1:CAS:528:DC%2BC3MXntFKrsb0%3D
-
Qian BZ, Li J, Zhang H, Kitamura T, Zhang J, Campion LR, Kaiser EA, Snyder LA, Pollard JW (2011) CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature 475(7355):222-225
-
(2011)
Nature
, vol.475
, Issue.7355
, pp. 222-225
-
-
Qian, B.Z.1
Li, J.2
Zhang, H.3
Kitamura, T.4
Zhang, J.5
Campion, L.R.6
Kaiser, E.A.7
Snyder, L.A.8
Pollard, J.W.9
-
40
-
-
84866784798
-
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
-
22039576 10.1158/2159-8274.CD-10-0028 1:CAS:528:DC%2BC3MXpsVylsbo%3D
-
DeNardo DG, Brennan DJ, Rexhepaj E, Ruffell B, Shiao SL, Madden SF, Gallagher WM, Wadhwani N, Keil SD, Junaid SA, Rugo HS, Hwang ES, Jirstrom K, West BL, Coussens LM (2011) Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov 1(1):54-67
-
(2011)
Cancer Discov
, vol.1
, Issue.1
, pp. 54-67
-
-
Denardo, D.G.1
Brennan, D.J.2
Rexhepaj, E.3
Ruffell, B.4
Shiao, S.L.5
Madden, S.F.6
Gallagher, W.M.7
Wadhwani, N.8
Keil, S.D.9
Junaid, S.A.10
Rugo, H.S.11
Hwang, E.S.12
Jirstrom, K.13
West, B.L.14
Coussens, L.M.15
-
41
-
-
77950944395
-
Macrophages, innate immunity and cancer: Balance, tolerance, and diversity
-
20144856 10.1016/j.coi.2010.01.009 1:CAS:528:DC%2BC3cXks1Srtr8%3D
-
Mantovani A, Sica A (2010) Macrophages, innate immunity and cancer: balance, tolerance, and diversity. Curr Opin Immunol 22(2):231-237
-
(2010)
Curr Opin Immunol
, vol.22
, Issue.2
, pp. 231-237
-
-
Mantovani, A.1
Sica, A.2
-
42
-
-
84862150896
-
Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer
-
22698406 10.1016/j.ccr.2012.04.025 1:CAS:528:DC%2BC38XosVaqtrw%3D
-
Bayne LJ, Beatty GL, Jhala N, Clark CE, Rhim AD, Stanger BZ, Vonderheide RH (2012) Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer. Cancer Cell 21(6):822-835
-
(2012)
Cancer Cell
, vol.21
, Issue.6
, pp. 822-835
-
-
Bayne, L.J.1
Beatty, G.L.2
Jhala, N.3
Clark, C.E.4
Rhim, A.D.5
Stanger, B.Z.6
Vonderheide, R.H.7
-
43
-
-
84862147254
-
Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia
-
22698407 10.1016/j.ccr.2012.04.024 1:CAS:528:DC%2BC38XosVeit7c%3D
-
Pylayeva-Gupta Y, Lee KE, Hajdu CH, Miller G, Bar-Sagi D (2012) Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia. Cancer Cell 21(6):836-847
-
(2012)
Cancer Cell
, vol.21
, Issue.6
, pp. 836-847
-
-
Pylayeva-Gupta, Y.1
Lee, K.E.2
Hajdu, C.H.3
Miller, G.4
Bar-Sagi, D.5
-
44
-
-
78149298209
-
Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha
-
10.1126/science.1195300
-
Kraman M, Bambrough PJ, Arnold JN, Roberts EW, Magiera L, Jones JO, Gopinathan A, Tuveson DA, Fearon DT (2011) Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha. Science 330(6005):827-830
-
(2011)
Science
, vol.330
, Issue.6005
, pp. 827-830
-
-
Kraman, M.1
Bambrough, P.J.2
Arnold, J.N.3
Roberts, E.W.4
Magiera, L.5
Jones, J.O.6
Gopinathan, A.7
Tuveson, D.A.8
Fearon, D.T.9
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