Non-physiological amino acid (NPAA) therapy targeting brain phenylalanine reduction: Pilot studies in PAH ENU2 mice

Journal of Inherited Metabolic Disease

Volumn 36, Issue 3, 2013, Pages 513-523

  Vogel, Kara R ^a   Arning, Erland ^b   Wasek, Brandi L ^b   Bottiglieri, Teodoro ^b   Gibson, K Michael ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 2 METHYLPROPIONIC ACID; 2 AMINOBICYCLO[2.2.1]HEPTANE 2 CARBOXYLIC ACID; 2 METHYL 2 METHYLAMINOPROPIONIC ACID; ALANINE TRANSPORTER; AMINO ACID TRANSPORTER; BRANCHED CHAIN AMINO ACID; METHIONINE; NORLEUCINE; PHENYLALANINE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID BRAIN LEVEL; AMINO ACID TRANSPORT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET THERAPY; IN VIVO STUDY; MOUSE; NONHUMAN; PHENYLKETONURIA; PILOT STUDY;

AMINO ACIDS; AMINO ACIDS, CYCLIC; AMINOISOBUTYRIC ACIDS; ANIMALS; BRAIN; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MOLECULAR TARGETED THERAPY; NORLEUCINE; PHENYLALANINE; PHENYLKETONURIAS; PILOT PROJECTS;

EID: 84877772598     PISSN: 01418955     EISSN: 15732665     Source Type: Journal    
DOI: 10.1007/s10545-012-9524-8     Document Type: Article

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