Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase

Journal of Medicinal Chemistry

Volumn 56, Issue 9, 2013, Pages 3609-3619

  Paulsen, Eleonora S ^a   Villadsen, Jesper ^a,d   Tenori, Eleonora ^a,e   Liu, Huizhen ^a   Bonde, Ditte F ^b,c   Lie, Mette A ^b   Bublitz, Maike ^b,c   Olesen, Claus ^b,c   Autzen, Henriette E ^b   Dach, Ingrid ^b,c   Sehgal, Pankaj ^b,c   Nissen, Poul ^c   Møller, Jesper V ^b,c   Schiøtt, Birgit ^b   Christensen, S Brøgger ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c DANISH NATIONAL RESEARCH FOUNDATION   (Denmark)

^d TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^e UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; THAPSIGARGIN; WATER;

ARTICLE; BINDING AFFINITY; CHEMICAL BINDING; CHEMICAL INTERACTION; CRYSTAL STRUCTURE; HYDROGEN BOND; SYNTHESIS;

ANTINEOPLASTIC AGENTS; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THAPSIGARGIN; WATER;

EID: 84877718314     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm4001083     Document Type: Article

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