Extensive mutagenesis of the HSV-1 gB ectodomain reveals remarkable stability of its postfusion form

Journal of Molecular Biology

Volumn 425, Issue 11, 2013, Pages 2056-2071

  Vitu, Elvira ^a   Sharma, Sapna ^a   Stampfer, Samuel D ^a   Heldwein, Ekaterina E ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

membrane fusion; protein engineering; structure; viral fusogen

Indexed keywords

GLYCOPROTEIN B; MUTANT PROTEIN; VIRUS FUSION PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HERPES SIMPLEX VIRUS 1; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN STABILITY; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; VIRUS ENTRY; VIRUS ENVELOPE;

HUMAN HERPESVIRUS 1;

EID: 84877706768     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.03.001     Document Type: Article

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