CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 3, 2012, Pages 1117-1129

  Xu, Jianhua ^a   Morris, Lynsie M ^a   Michalakis, Stylianos ^b   Biel, Martin ^b   Fliesler, Steven J ^c,d,e,f   Sherry, David M ^a,g   Ding, Xi Qin ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

^c VA WESTERN NEW YORK HEALTHCARE SYSTEM   (United States)

^d UNIVERSITY AT BUFFALO   (United States)

^e UNIVERSITY AT BUFFALO   (United States)

^f SUNY EYE INSTITUTE   (United States)

^g UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC NUCLEOTIDE GATED CHANNEL; CYCLIC NUCLEOTIDE GATED CHANNEL A3; GLUTAMIC ACID; GLUTAMIC ACID RICH PROTEIN; RHODOPSIN; ROD TRANSDUCIN ALPHA SUBUNIT; TRANSDUCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRORETINOGRAPHY; ENZYME ACTIVITY; MORPHOMETRICS; MOUSE; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; RETINA CONE; RETINA DEGENERATION; RETINA ROD; VISUAL SYSTEM FUNCTION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; ARRESTIN; BLOTTING, WESTERN; CELL SURVIVAL; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; ELECTRORETINOGRAPHY; HETEROTRIMERIC GTP-BINDING PROTEINS; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; PRESYNAPTIC TERMINALS; RETINAL CONE PHOTORECEPTOR CELLS; RETINAL DEGENERATION; RETINAL ROD PHOTORECEPTOR CELLS; RHODOPSIN; ROD OPSINS; TRANSDUCIN; VISION, OCULAR;

EID: 84863256202     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-8168     Document Type: Article

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