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Volumn 55, Issue , 2013, Pages 110-119

Increased excitability in tat-transgenic mice: Role of tat in HIV-related neurological disorders

Author keywords

HIV 1 associated neurocognitive disorders; HIV 1 tat transgenic mice; Kainate; Neurodegeneration; Seizures

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMIC ACID; KAINIC ACID; TRANSACTIVATOR PROTEIN;

EID: 84877636417     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.02.004     Document Type: Article
Times cited : (40)

References (71)
  • 1
    • 34248567671 scopus 로고    scopus 로고
    • Preventing HIV-1 Tat-induced neuronal apoptosis using antioxidant enzymes: mechanistic and therapeutic implications
    • Agrawal L., et al. Preventing HIV-1 Tat-induced neuronal apoptosis using antioxidant enzymes: mechanistic and therapeutic implications. Virology 2007, 363:462-472.
    • (2007) Virology , vol.363 , pp. 462-472
    • Agrawal, L.1
  • 2
    • 84855760098 scopus 로고    scopus 로고
    • HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes
    • Agrawal L., et al. HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes. Neurobiol. Dis. 2012, 45:657-670.
    • (2012) Neurobiol. Dis. , vol.45 , pp. 657-670
    • Agrawal, L.1
  • 3
    • 0035827452 scopus 로고    scopus 로고
    • Oxidative damage induced by the injection of HIV-1 Tat protein in the rat striatum
    • Aksenov M.Y., et al. Oxidative damage induced by the injection of HIV-1 Tat protein in the rat striatum. Neurosci. Lett. 2001, 305(1):5-8.
    • (2001) Neurosci. Lett. , vol.305 , Issue.1 , pp. 5-8
    • Aksenov, M.Y.1
  • 4
    • 13144251117 scopus 로고    scopus 로고
    • HIV-1 Tat protein mimicry of chemokines
    • Albini A., et al. HIV-1 Tat protein mimicry of chemokines. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:13153-13158.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 13153-13158
    • Albini, A.1
  • 5
    • 0032921875 scopus 로고    scopus 로고
    • Morphological, histochemical, immunohistochemical, and ultrastructural characterization of tumors, dysplastic and non-neoplastic lesions arising in BK virus/tat transgenic mice
    • Altavilla G., et al. Morphological, histochemical, immunohistochemical, and ultrastructural characterization of tumors, dysplastic and non-neoplastic lesions arising in BK virus/tat transgenic mice. Am. J. Pathol. 1999, 154:1231-1244.
    • (1999) Am. J. Pathol. , vol.154 , pp. 1231-1244
    • Altavilla, G.1
  • 6
    • 0021967217 scopus 로고
    • Trans-activator gene of human T-lymphotropic virus type III (HTLV-III)
    • Arya S.K., et al. Trans-activator gene of human T-lymphotropic virus type III (HTLV-III). Science 1985, 229:69-73.
    • (1985) Science , vol.229 , pp. 69-73
    • Arya, S.K.1
  • 7
    • 0032930065 scopus 로고    scopus 로고
    • Isolated, chronic, epilepsia partialis continua in an HIV-infected patient
    • Bartolomei F., et al. Isolated, chronic, epilepsia partialis continua in an HIV-infected patient. Arch. Neurol. 1999, 56:111-114.
    • (1999) Arch. Neurol. , vol.56 , pp. 111-114
    • Bartolomei, F.1
  • 8
    • 2442432175 scopus 로고    scopus 로고
    • HIV secreted protein Tat prevents long-term potentiation in the hippocampal CA1 region
    • Behnisch T., et al. HIV secreted protein Tat prevents long-term potentiation in the hippocampal CA1 region. Brain Res. 2004, 1012:187-189.
    • (2004) Brain Res. , vol.1012 , pp. 187-189
    • Behnisch, T.1
  • 9
    • 0026697292 scopus 로고
    • Functional evidence for multiple GABAB receptor subtypes in the rat cerebral cortex
    • Bonanno G., Raiteri M. Functional evidence for multiple GABAB receptor subtypes in the rat cerebral cortex. J. Pharmacol. Exp. Ther. 1993, 262:114-118.
    • (1993) J. Pharmacol. Exp. Ther. , vol.262 , pp. 114-118
    • Bonanno, G.1    Raiteri, M.2
  • 10
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 11
    • 38749114261 scopus 로고    scopus 로고
    • Excitatory effects of human immunodeficiency virus 1 Tat on cultured rat cerebral cortical neurons
    • Brailoiu G.C., et al. Excitatory effects of human immunodeficiency virus 1 Tat on cultured rat cerebral cortical neurons. Neuroscience 2008, 151:701-710.
    • (2008) Neuroscience , vol.151 , pp. 701-710
    • Brailoiu, G.C.1
  • 12
    • 0037111839 scopus 로고    scopus 로고
    • Involvement of the neuropeptide nociceptin/orphanin FQ in kainate seizures
    • Bregola G., et al. Involvement of the neuropeptide nociceptin/orphanin FQ in kainate seizures. J. Neurosci. 2002, 22:10030-10038.
    • (2002) J. Neurosci. , vol.22 , pp. 10030-10038
    • Bregola, G.1
  • 13
    • 51349138034 scopus 로고    scopus 로고
    • Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV-1 Tat transgenic mice
    • Bruce-Keller A.J., et al. Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV-1 Tat transgenic mice. Glia 2008, 56:1414-1427.
    • (2008) Glia , vol.56 , pp. 1414-1427
    • Bruce-Keller, A.J.1
  • 14
    • 0030862924 scopus 로고    scopus 로고
    • HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region
    • Chang H.C., et al. HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region. AIDS 1997, 12:1421-1431.
    • (1997) AIDS , vol.12 , pp. 1421-1431
    • Chang, H.C.1
  • 15
    • 0030962775 scopus 로고    scopus 로고
    • Neuronal excitatory properties of human immunodeficiency virus type 1 Tat protein
    • Cheng J., et al. Neuronal excitatory properties of human immunodeficiency virus type 1 Tat protein. Neuroscience 1998, 82:97-106.
    • (1998) Neuroscience , vol.82 , pp. 97-106
    • Cheng, J.1
  • 16
    • 0027371069 scopus 로고
    • Systemic expression of HIV-1 tat gene in transgenic mice induces endothelial proliferation and tumors of different histotypes
    • Corallini A., et al. Systemic expression of HIV-1 tat gene in transgenic mice induces endothelial proliferation and tumors of different histotypes. Cancer Res. 1993, 53:5569-5575.
    • (1993) Cancer Res. , vol.53 , pp. 5569-5575
    • Corallini, A.1
  • 17
    • 0030430509 scopus 로고    scopus 로고
    • Prospective analysis of seizure occurring in human immunodeficiency virus type-1 infection
    • Dore G.J., et al. Prospective analysis of seizure occurring in human immunodeficiency virus type-1 infection. J. NeuroAIDS 1996, 1:59-69.
    • (1996) J. NeuroAIDS , vol.1 , pp. 59-69
    • Dore, G.J.1
  • 18
    • 0022531676 scopus 로고
    • A rapid method for isolation of synaptosomes on Percoll gradient
    • Dunkley P.R., et al. A rapid method for isolation of synaptosomes on Percoll gradient. Brain Res. 1986, 372:115-129.
    • (1986) Brain Res. , vol.372 , pp. 115-129
    • Dunkley, P.R.1
  • 19
    • 0027458469 scopus 로고
    • Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation
    • Ensoli B., et al. Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J. Virol. 1993, 67:277-287.
    • (1993) J. Virol. , vol.67 , pp. 277-287
    • Ensoli, B.1
  • 20
    • 0038579653 scopus 로고    scopus 로고
    • MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis
    • Eugenin E.A., et al. MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis. J. Neurochem. 2003, 85:1299-1311.
    • (2003) J. Neurochem. , vol.85 , pp. 1299-1311
    • Eugenin, E.A.1
  • 21
    • 33847649975 scopus 로고    scopus 로고
    • HIV-tat induces formation of an LRP-PSD-95-NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes
    • Eugenin E.A., et al. HIV-tat induces formation of an LRP-PSD-95-NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:3434-3438.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 3434-3438
    • Eugenin, E.A.1
  • 22
    • 0032895217 scopus 로고    scopus 로고
    • Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder
    • Everall I.P., et al. Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder. Brain Pathol. 1999, 9:209-217.
    • (1999) Brain Pathol. , vol.9 , pp. 209-217
    • Everall, I.P.1
  • 23
    • 34447298369 scopus 로고    scopus 로고
    • Reduction of corticostriatal glutamatergic fibers in basic fibroblast growth factor deficient mice is associated with hyperactivity and enhanced dopaminergic transmission
    • Fadda P., et al. Reduction of corticostriatal glutamatergic fibers in basic fibroblast growth factor deficient mice is associated with hyperactivity and enhanced dopaminergic transmission. Biol. Psychiatry 2007, 62:235-242.
    • (2007) Biol. Psychiatry , vol.62 , pp. 235-242
    • Fadda, P.1
  • 24
    • 0043135217 scopus 로고    scopus 로고
    • The human immunodeficiency virus-1 protein Tat and its discrete fragments evoke selective release of acetylcholine from human and rat cerebrocortical terminals through species-specific mechanisms
    • Feligioni M., et al. The human immunodeficiency virus-1 protein Tat and its discrete fragments evoke selective release of acetylcholine from human and rat cerebrocortical terminals through species-specific mechanisms. J. Neurosci. 2003, 23:6810-6818.
    • (2003) J. Neurosci. , vol.23 , pp. 6810-6818
    • Feligioni, M.1
  • 25
    • 0042355293 scopus 로고    scopus 로고
    • Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time
    • Ferrari A., et al. Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time. Mol. Ther. 2003, 8:284-294.
    • (2003) Mol. Ther. , vol.8 , pp. 284-294
    • Ferrari, A.1
  • 26
    • 63349109514 scopus 로고    scopus 로고
    • The human immunodeficiency virus-1-associated protein, Tat1-86, impairs dopamine transporters and interacts with cocaine to reduce nerve terminal function: a no-net-flux microdialysis study
    • Ferris M.J., et al. The human immunodeficiency virus-1-associated protein, Tat1-86, impairs dopamine transporters and interacts with cocaine to reduce nerve terminal function: a no-net-flux microdialysis study. Neuroscience 2009, 159:1292-1299.
    • (2009) Neuroscience , vol.159 , pp. 1292-1299
    • Ferris, M.J.1
  • 27
    • 0037229559 scopus 로고    scopus 로고
    • Methamphetamine potentiates HIV-1 Tat protein-mediated activation of redox-sensitive pathways in discrete regions of the brain
    • Flora G., et al. Methamphetamine potentiates HIV-1 Tat protein-mediated activation of redox-sensitive pathways in discrete regions of the brain. Exp. Neurol. 2003, 179(1):60-70.
    • (2003) Exp. Neurol. , vol.179 , Issue.1 , pp. 60-70
    • Flora, G.1
  • 28
    • 0024262589 scopus 로고
    • Cellular uptake of the Tat protein from human immunodeficiency virus
    • Frankel A.D., Pabo C.O. Cellular uptake of the Tat protein from human immunodeficiency virus. Cell 1988, 55:1189-1193.
    • (1988) Cell , vol.55 , pp. 1189-1193
    • Frankel, A.D.1    Pabo, C.O.2
  • 29
    • 0034614528 scopus 로고    scopus 로고
    • Tat mediates apoptosis in vivo in the rat central nervous system
    • Gavriil E.S., et al. Tat mediates apoptosis in vivo in the rat central nervous system. Biochem. Biophys. Res. Commun. 2000, 267(1):252-256.
    • (2000) Biochem. Biophys. Res. Commun. , vol.267 , Issue.1 , pp. 252-256
    • Gavriil, E.S.1
  • 30
    • 0025609978 scopus 로고
    • Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1
    • Giulian D., et al. Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science 1990, 250:1593-1596.
    • (1990) Science , vol.250 , pp. 1593-1596
    • Giulian, D.1
  • 31
    • 77957884283 scopus 로고    scopus 로고
    • HIV-Tat elicits microglial glutamate release: role of NAPDH oxidase and the cystine-glutamate antiporter
    • Gupta S., et al. HIV-Tat elicits microglial glutamate release: role of NAPDH oxidase and the cystine-glutamate antiporter. Neurosci. Lett. 2010, 485:233-236.
    • (2010) Neurosci. Lett. , vol.485 , pp. 233-236
    • Gupta, S.1
  • 32
    • 0032847276 scopus 로고    scopus 로고
    • Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein Tat
    • Haughey N.J., et al. Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein Tat. J. Neurochem. 1999, 73:1363-1374.
    • (1999) J. Neurochem. , vol.73 , pp. 1363-1374
    • Haughey, N.J.1
  • 33
    • 0034909804 scopus 로고    scopus 로고
    • HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity
    • Haughey N.J., et al. HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity. J. Neurochem. 2001, 78:457-467.
    • (2001) J. Neurochem. , vol.78 , pp. 457-467
    • Haughey, N.J.1
  • 34
    • 0034025075 scopus 로고    scopus 로고
    • Detection of human immunodeficiency virus regulatory protein Tat in CNS tissues
    • Hudson L., et al. Detection of human immunodeficiency virus regulatory protein Tat in CNS tissues. J. Neurovirol. 2000, 6:145-155.
    • (2000) J. Neurovirol. , vol.6 , pp. 145-155
    • Hudson, L.1
  • 35
    • 0032520845 scopus 로고    scopus 로고
    • A point mutation (D79N) of the alpha2A adrenergic receptor abolishes the antiepileptogenic action of endogenous norepinephrine
    • Janumpalli S., et al. A point mutation (D79N) of the alpha2A adrenergic receptor abolishes the antiepileptogenic action of endogenous norepinephrine. J. Neurosci. 1998, 18:2004-2008.
    • (1998) J. Neurosci. , vol.18 , pp. 2004-2008
    • Janumpalli, S.1
  • 36
    • 0031747096 scopus 로고    scopus 로고
    • Intraventricular injection of human immunodeficiency virus type 1 (HIV-1) tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement
    • Jones M., et al. Intraventricular injection of human immunodeficiency virus type 1 (HIV-1) tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement. J. Neuropathol. Exp. Neurol. 1998, 57(6):563-570.
    • (1998) J. Neuropathol. Exp. Neurol. , vol.57 , Issue.6 , pp. 563-570
    • Jones, M.1
  • 37
    • 22744455058 scopus 로고    scopus 로고
    • HIV-1 infection and AIDS: consequences for the central nervous system
    • Kaul M., et al. HIV-1 infection and AIDS: consequences for the central nervous system. Cell Death Differ. 2005, 12:878-892.
    • (2005) Cell Death Differ. , vol.12 , pp. 878-892
    • Kaul, M.1
  • 38
    • 0037406230 scopus 로고    scopus 로고
    • Neuropathologies in transgenic mice expressing human immunodeficiency virus type 1 Tat protein under the regulation of the astrocyte-specific glial fibrillary acidic protein promoter and doxycycline
    • Kim B.O., et al. Neuropathologies in transgenic mice expressing human immunodeficiency virus type 1 Tat protein under the regulation of the astrocyte-specific glial fibrillary acidic protein promoter and doxycycline. Am. J. Pathol. 2003, 162:1693-1707.
    • (2003) Am. J. Pathol. , vol.162 , pp. 1693-1707
    • Kim, B.O.1
  • 39
    • 33744920797 scopus 로고    scopus 로고
    • HIV Tat and neurotoxicity
    • King J.E., et al. HIV Tat and neurotoxicity. Microbes Infect. 2006, 8:1347-1357.
    • (2006) Microbes Infect. , vol.8 , pp. 1347-1357
    • King, J.E.1
  • 40
    • 58149393846 scopus 로고    scopus 로고
    • NMDA receptor activation by HIV-Tat protein is clade dependent
    • Li W., et al. NMDA receptor activation by HIV-Tat protein is clade dependent. J. Neurosci. 2008, 28:12190-12198.
    • (2008) J. Neurosci. , vol.28 , pp. 12190-12198
    • Li, W.1
  • 41
    • 77955983504 scopus 로고    scopus 로고
    • HIV-1 associated neurocognitive disorder: pathogenesis and therapeutic opportunities
    • Lindl K.A., et al. HIV-1 associated neurocognitive disorder: pathogenesis and therapeutic opportunities. J. Neuroimmune Pharmacol. 2010, 5:294-309.
    • (2010) J. Neuroimmune Pharmacol. , vol.5 , pp. 294-309
    • Lindl, K.A.1
  • 42
    • 33646787850 scopus 로고    scopus 로고
    • The human immunodeficiency virus-1 protein Tat upregulates NMDA receptor function by acting at mGluR1 receptors coexisting on human and rat brain noradrenergic neurons
    • Longordo F., et al. The human immunodeficiency virus-1 protein Tat upregulates NMDA receptor function by acting at mGluR1 receptors coexisting on human and rat brain noradrenergic neurons. J. Pharmacol. Exp. Ther. 2006, 317:1097-1105.
    • (2006) J. Pharmacol. Exp. Ther. , vol.317 , pp. 1097-1105
    • Longordo, F.1
  • 43
    • 36849072696 scopus 로고    scopus 로고
    • N-methyl-d-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus
    • Luccini E., et al. N-methyl-d-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus. J. Neurosci. Res. 2007, 85:3657-3665.
    • (2007) J. Neurosci. Res. , vol.85 , pp. 3657-3665
    • Luccini, E.1
  • 44
    • 0026739853 scopus 로고
    • Spectrum of human immunodeficiency virus-associated neocortical damage
    • Masliah E., et al. Spectrum of human immunodeficiency virus-associated neocortical damage. Ann. Neurol. 1992, 32:321-329.
    • (1992) Ann. Neurol. , vol.32 , pp. 321-329
    • Masliah, E.1
  • 45
    • 0033559757 scopus 로고    scopus 로고
    • Human immunodeficiency virus replication induces monocyte chemotactic protein-1 in human macrophages and U937 promonocytic cells
    • Mengozzi M., et al. Human immunodeficiency virus replication induces monocyte chemotactic protein-1 in human macrophages and U937 promonocytic cells. Blood 1999, 93:1851-1857.
    • (1999) Blood , vol.93 , pp. 1851-1857
    • Mengozzi, M.1
  • 46
    • 3142673373 scopus 로고    scopus 로고
    • Multiple actions of the human immunodeficiency virus type-1 Tat protein on microglial cell functions
    • Minghetti L., et al. Multiple actions of the human immunodeficiency virus type-1 Tat protein on microglial cell functions. Neurochem. Res. 2004, 29:965-978.
    • (2004) Neurochem. Res. , vol.29 , pp. 965-978
    • Minghetti, L.1
  • 47
    • 0037110425 scopus 로고    scopus 로고
    • New onset seizures in HIV-infected patients without intracranial mass lesions or meningitis-a clinical, radiological and SPECT scan study
    • Modi G., et al. New onset seizures in HIV-infected patients without intracranial mass lesions or meningitis-a clinical, radiological and SPECT scan study. J. Neurol. Sci. 2002, 202:29-34.
    • (2002) J. Neurol. Sci. , vol.202 , pp. 29-34
    • Modi, G.1
  • 48
    • 77955975630 scopus 로고    scopus 로고
    • The HIV-1 viral protein Tat increases glutamate and decreases GABA exocytosis from human and mouse neocortical nerve endings
    • Musante V., et al. The HIV-1 viral protein Tat increases glutamate and decreases GABA exocytosis from human and mouse neocortical nerve endings. Cereb. Cortex 2010, 20:1974-1984.
    • (2010) Cereb. Cortex , vol.20 , pp. 1974-1984
    • Musante, V.1
  • 50
    • 0030610164 scopus 로고    scopus 로고
    • Characterization of glutamate and [3H]d-aspartate outflow from various in vitro preparations of the rat hippocampus
    • Muzzolini A., et al. Characterization of glutamate and [3H]d-aspartate outflow from various in vitro preparations of the rat hippocampus. Neurochem. Int. 1997, 31:113-124.
    • (1997) Neurochem. Int. , vol.31 , pp. 113-124
    • Muzzolini, A.1
  • 51
    • 0031974964 scopus 로고    scopus 로고
    • Neurobiological aspects of HIV infections: neurotoxic mechanisms
    • Nath A., Geiger J.D. Neurobiological aspects of HIV infections: neurotoxic mechanisms. Prog. Neurobiol. 1998, 54:19-33.
    • (1998) Prog. Neurobiol. , vol.54 , pp. 19-33
    • Nath, A.1    Geiger, J.D.2
  • 52
    • 0022518134 scopus 로고
    • The AIDS dementia complex: I. Clinical features
    • Navia B.A., Jordan B.D., Price R.W. The AIDS dementia complex: I. Clinical features. Ann. Neurol. 1986, 19:517-524.
    • (1986) Ann. Neurol. , vol.19 , pp. 517-524
    • Navia, B.A.1    Jordan, B.D.2    Price, R.W.3
  • 53
    • 66349121666 scopus 로고    scopus 로고
    • Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model
    • Paradiso B., et al. Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:7191-7196.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 7191-7196
    • Paradiso, B.1
  • 55
    • 73149112608 scopus 로고    scopus 로고
    • The HIV-1 transgenic rat as a model for HIV-1 infected individuals on HAART
    • Peng J., et al. The HIV-1 transgenic rat as a model for HIV-1 infected individuals on HAART. J. Neuroimmunol. 2010, 218(1-2):94-101.
    • (2010) J. Neuroimmunol. , vol.218 , Issue.1-2 , pp. 94-101
    • Peng, J.1
  • 56
    • 34547236227 scopus 로고    scopus 로고
    • Antidepressant treatments and function of glutamate ionotropic receptors mediating amine release in hippocampus
    • Pittaluga A., et al. Antidepressant treatments and function of glutamate ionotropic receptors mediating amine release in hippocampus. Neuropharmacology 2007, 53:27-36.
    • (2007) Neuropharmacology , vol.53 , pp. 27-36
    • Pittaluga, A.1
  • 57
    • 0037044856 scopus 로고    scopus 로고
    • Neurotoxic effects of the human immunodeficiency virus type-1 transcription factor Tat require function of a polyamine sensitive-site on the N-methyl-d-aspartate receptor
    • Prendergast M.A., et al. Neurotoxic effects of the human immunodeficiency virus type-1 transcription factor Tat require function of a polyamine sensitive-site on the N-methyl-d-aspartate receptor. Brain Res. 2002, 954:300-307.
    • (2002) Brain Res. , vol.954 , pp. 300-307
    • Prendergast, M.A.1
  • 58
    • 0034302965 scopus 로고    scopus 로고
    • Synaptosomes still viable after 25years of superfusion
    • Raiteri L., Raiteri M. Synaptosomes still viable after 25years of superfusion. Neurochem. Res. 2000, 25:1265-1274.
    • (2000) Neurochem. Res. , vol.25 , pp. 1265-1274
    • Raiteri, L.1    Raiteri, M.2
  • 59
    • 0026008006 scopus 로고
    • Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1
    • Sabatier J.M., et al. Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1. J. Virol. 1991, 65:961-967.
    • (1991) J. Virol. , vol.65 , pp. 961-967
    • Sabatier, J.M.1
  • 60
    • 0034714392 scopus 로고    scopus 로고
    • Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration
    • Schmued L.C., Hopkins K.J. Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res. 2000, 874:123-130.
    • (2000) Brain Res. , vol.874 , pp. 123-130
    • Schmued, L.C.1    Hopkins, K.J.2
  • 61
    • 0033520487 scopus 로고    scopus 로고
    • In vivo protein transduction: delivery of a biologically active protein into the mouse
    • Schwarze S.R., et al. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 1999, 285(5433):1569-1572.
    • (1999) Science , vol.285 , Issue.5433 , pp. 1569-1572
    • Schwarze, S.R.1
  • 62
    • 20544465125 scopus 로고    scopus 로고
    • Memory loss in persons with HIV/AIDS: assessment and strategies for coping
    • Selnes O.A. Memory loss in persons with HIV/AIDS: assessment and strategies for coping. AIDS Read. 2005, 15:289-292.
    • (2005) AIDS Read. , vol.15 , pp. 289-292
    • Selnes, O.A.1
  • 63
    • 70449650501 scopus 로고    scopus 로고
    • Neurological presentation of AIDS
    • Singer E.J., et al. Neurological presentation of AIDS. Neurol. Clin. 2010, 28:253-275.
    • (2010) Neurol. Clin. , vol.28 , pp. 253-275
    • Singer, E.J.1
  • 64
    • 31444433387 scopus 로고    scopus 로고
    • Confusion, memory disorders, and ophthalmoparesis in a patient with AIDS
    • Tattevin P., et al. Confusion, memory disorders, and ophthalmoparesis in a patient with AIDS. Lancet 2006, 367:368.
    • (2006) Lancet , vol.367 , pp. 368
    • Tattevin, P.1
  • 65
    • 0026533581 scopus 로고
    • Protection from kainic acid neuropathological syndrome by NMDA receptor antagonists: effect of MK-801 and CGP 39551 on neurotransmitter and glial markers
    • Virgili M., et al. Protection from kainic acid neuropathological syndrome by NMDA receptor antagonists: effect of MK-801 and CGP 39551 on neurotransmitter and glial markers. Neuropharmacology 1992, 5:469-474.
    • (1992) Neuropharmacology , vol.5 , pp. 469-474
    • Virgili, M.1
  • 66
    • 0027254101 scopus 로고
    • Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia
    • Wessenligh S.L. Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia. Ann. Neurol. 1993, 33:576-582.
    • (1993) Ann. Neurol. , vol.33 , pp. 576-582
    • Wessenligh, S.L.1
  • 67
    • 0029029058 scopus 로고
    • Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120
    • Westendorp M.O., et al. Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature 1995, 375:497-500.
    • (1995) Nature , vol.375 , pp. 497-500
    • Westendorp, M.O.1
  • 68
    • 0034635394 scopus 로고    scopus 로고
    • HIV-1 Tat-mediated inhibition of the tyrosine hydroxylase gene expression in dopaminergic neuronal cells
    • Zauli G., et al. HIV-1 Tat-mediated inhibition of the tyrosine hydroxylase gene expression in dopaminergic neuronal cells. J. Biol. Chem. 2000, 275(6):4159-4165.
    • (2000) J. Biol. Chem. , vol.275 , Issue.6 , pp. 4159-4165
    • Zauli, G.1
  • 69
    • 66749106440 scopus 로고    scopus 로고
    • HIV-1 Tat protein-induced rapid and reversible decrease in [3H]dopamine uptake: dissociation of [3H]dopamine uptake and [3H]2beta-carbomethoxy-3-beta-(4-fluorophenyl)tropane (WIN 35,428) binding in rat striatal synaptosomes
    • Zhu J., et al. HIV-1 Tat protein-induced rapid and reversible decrease in [3H]dopamine uptake: dissociation of [3H]dopamine uptake and [3H]2beta-carbomethoxy-3-beta-(4-fluorophenyl)tropane (WIN 35,428) binding in rat striatal synaptosomes. J. Pharmacol. Exp. Ther. 2009, 329:1071-1083.
    • (2009) J. Pharmacol. Exp. Ther. , vol.329 , pp. 1071-1083
    • Zhu, J.1
  • 70
    • 0037113355 scopus 로고    scopus 로고
    • Neuroprotective activity of CHF3381, a putative N-methyl-d-aspartate receptor antagonist
    • Zucchini S., et al. Neuroprotective activity of CHF3381, a putative N-methyl-d-aspartate receptor antagonist. NeuroReport 2002, 13:2071-2074.
    • (2002) NeuroReport , vol.13 , pp. 2071-2074
    • Zucchini, S.1
  • 71
    • 58149390185 scopus 로고    scopus 로고
    • FGF-2 overexpression increases excitability and seizure susceptibility but decreases seizure-induced cell loss
    • Zucchini S., et al. FGF-2 overexpression increases excitability and seizure susceptibility but decreases seizure-induced cell loss. J. Neurosci. 2008, 49:13112-13124.
    • (2008) J. Neurosci. , vol.49 , pp. 13112-13124
    • Zucchini, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.