메뉴 건너뛰기




Volumn 15, Issue 6, 2013, Pages 485-502

Combination therapy with GLP-1 receptor agonists and basal insulin: A systematic review of the literature

Author keywords

GLP 1; Glycaemic control; Insulin therapy; Type 2 diabetes

Indexed keywords

EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; GLUCOSE; HEMOGLOBIN A1C; INSULIN; INSULIN DETEMIR; INSULIN GLARGINE; INSULIN LISPRO; LIRAGLUTIDE; LIXISENATIDE; METFORMIN; PLACEBO;

EID: 84877633796     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/dom.12025     Document Type: Review
Times cited : (127)

References (79)
  • 1
    • 77953088767 scopus 로고    scopus 로고
    • New perspectives in type 2 diabetes, cardiovascular risk, and treatment goals
    • Wysham CH. New perspectives in type 2 diabetes, cardiovascular risk, and treatment goals. Postgrad Med 2010; 122: 52-60.
    • (2010) Postgrad Med , vol.122 , pp. 52-60
    • Wysham, C.H.1
  • 2
    • 84864285795 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • Inzucchi SE, Bergenstal RM, Buse JB et al. Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2012; 55: 1577-1596.
    • (2012) Diabetes Care , vol.55 , pp. 1577-1596
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3
  • 3
    • 0031921748 scopus 로고    scopus 로고
    • Response to intensive therapy steps and to glipizide dose in combination with insulin in type 2 diabetes. VA feasibility study on glycemic control and complications (VA CSDM)
    • Abraira C, Henderson WG, Colwell JA et al. Response to intensive therapy steps and to glipizide dose in combination with insulin in type 2 diabetes. VA feasibility study on glycemic control and complications (VA CSDM). Diabetes Care 1998; 21: 574-579.
    • (1998) Diabetes Care , vol.21 , pp. 574-579
    • Abraira, C.1    Henderson, W.G.2    Colwell, J.A.3
  • 4
    • 40149108459 scopus 로고    scopus 로고
    • The impact of diabetes and associated cardiometabolic risk factors on members: Strategies for optimizing outcomes
    • Hoerger TJ, Ahmann AJ. The impact of diabetes and associated cardiometabolic risk factors on members: Strategies for optimizing outcomes. J Manag Care Pharm 2008; 14: S2-S14.
    • (2008) J Manag Care Pharm , vol.14
    • Hoerger, T.J.1    Ahmann, A.J.2
  • 5
    • 67650472212 scopus 로고    scopus 로고
    • Treatment approach and HbA1c control among US adults with type 2 diabetes: NHANES 1999-2004
    • Dodd AH, Colby MS, Boye KS, Fahlman C, Kim S, Briefel RR. Treatment approach and HbA1c control among US adults with type 2 diabetes: NHANES 1999-2004. Curr Med Res Opin 2009; 25: 1605-1613.
    • (2009) Curr Med Res Opin , vol.25 , pp. 1605-1613
    • Dodd, A.H.1    Colby, M.S.2    Boye, K.S.3    Fahlman, C.4    Kim, S.5    Briefel, R.R.6
  • 6
    • 1042280201 scopus 로고    scopus 로고
    • Glycemic control from 1988 to 2000 among U.S. adults diagnosed with type 2 diabetes: a preliminary report
    • Koro CE, Bowlin SJ, Bourgeois N, Fedder DO. Glycemic control from 1988 to 2000 among U.S. adults diagnosed with type 2 diabetes: a preliminary report. Diabetes Care 2004; 27: 17-20.
    • (2004) Diabetes Care , vol.27 , pp. 17-20
    • Koro, C.E.1    Bowlin, S.J.2    Bourgeois, N.3    Fedder, D.O.4
  • 7
    • 0242269000 scopus 로고    scopus 로고
    • The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients
    • Riddle MC, Rosenstock J, Gerich J. The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care 2003; 26: 3080-3086.
    • (2003) Diabetes Care , vol.26 , pp. 3080-3086
    • Riddle, M.C.1    Rosenstock, J.2    Gerich, J.3
  • 8
    • 33646110527 scopus 로고    scopus 로고
    • Addition of rapid-acting insulin to basal insulin therapy in type 2 diabetes: indications and modalities
    • Monnier L, Colette C. Addition of rapid-acting insulin to basal insulin therapy in type 2 diabetes: indications and modalities. Diabetes Metab 2006; 32: 7-13.
    • (2006) Diabetes Metab , vol.32 , pp. 7-13
    • Monnier, L.1    Colette, C.2
  • 9
    • 84855371526 scopus 로고    scopus 로고
    • Hypoglycemia and adverse outcomes: marker or mediator?
    • Lipska KJ, Kosiborod M. Hypoglycemia and adverse outcomes: marker or mediator? Rev Cardiovasc Med 2011; 12: 132-135.
    • (2011) Rev Cardiovasc Med , vol.12 , pp. 132-135
    • Lipska, K.J.1    Kosiborod, M.2
  • 10
    • 77956069166 scopus 로고    scopus 로고
    • Hypoglycemia, diabetes, and cardiovascular events
    • Desouza CV, Bolli GB, Fonseca V. Hypoglycemia, diabetes, and cardiovascular events. Diabetes Care 2010; 33: 1389-1394.
    • (2010) Diabetes Care , vol.33 , pp. 1389-1394
    • Desouza, C.V.1    Bolli, G.B.2    Fonseca, V.3
  • 11
    • 57249098943 scopus 로고    scopus 로고
    • The barrier of hypoglycemia in diabetes
    • Cryer PE. The barrier of hypoglycemia in diabetes. Diabetes 2008; 57: 3169-3176.
    • (2008) Diabetes , vol.57 , pp. 3169-3176
    • Cryer, P.E.1
  • 13
    • 37349008890 scopus 로고    scopus 로고
    • Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover noninferiority trial
    • Barnett AH, Burger J, Johns D et al. Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover noninferiority trial. Clin Ther 2007; 29: 2333-2348.
    • (2007) Clin Ther , vol.29 , pp. 2333-2348
    • Barnett, A.H.1    Burger, J.2    Johns, D.3
  • 14
    • 36049018619 scopus 로고    scopus 로고
    • Missing the point: substituting exenatide for nonoptimized insulin: going from bad to worse!
    • Rosenstock J, Fonseca V. Missing the point: substituting exenatide for nonoptimized insulin: going from bad to worse!. Diabetes Care 2007; 30: 2972-2973.
    • (2007) Diabetes Care , vol.30 , pp. 2972-2973
    • Rosenstock, J.1    Fonseca, V.2
  • 15
    • 53249142132 scopus 로고    scopus 로고
    • Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study
    • Drucker DJ, Buse JB, Taylor K et al. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet 2008; 372: 1240-1250.
    • (2008) Lancet , vol.372 , pp. 1240-1250
    • Drucker, D.J.1    Buse, J.B.2    Taylor, K.3
  • 16
    • 48949098988 scopus 로고    scopus 로고
    • Safety and efficacy of exenatide in combination with insulin in patients with type 2 diabetes mellitus
    • Sheffield CA, Kane MP, Busch RS, Bakst G, Abelseth JM, Hamilton RA. Safety and efficacy of exenatide in combination with insulin in patients with type 2 diabetes mellitus. Endocr Pract 2008; 14: 285-292.
    • (2008) Endocr Pract , vol.14 , pp. 285-292
    • Sheffield, C.A.1    Kane, M.P.2    Busch, R.S.3    Bakst, G.4    Abelseth, J.M.5    Hamilton, R.A.6
  • 17
    • 67649666737 scopus 로고    scopus 로고
    • Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
    • Buse JB, Rosenstock J, Sesti G et al. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet 2009; 374: 39-47.
    • (2009) Lancet , vol.374 , pp. 39-47
    • Buse, J.B.1    Rosenstock, J.2    Sesti, G.3
  • 20
    • 81155154236 scopus 로고    scopus 로고
    • Liraglutide: a review of its use in the management of type 2 diabetes mellitus
    • Perry CM. Liraglutide: a review of its use in the management of type 2 diabetes mellitus. Drugs 2011; 71: 2347-2373.
    • (2011) Drugs , vol.71 , pp. 2347-2373
    • Perry, C.M.1
  • 21
    • 79953040963 scopus 로고    scopus 로고
    • An overview of once-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for the future
    • Madsbad S, Kielgast U, Asmar M, Deacon CF, Torekov SS, Holst JJ. An overview of once-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for the future. Diabetes Obes Metab 2011; 13: 394-407.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 394-407
    • Madsbad, S.1    Kielgast, U.2    Asmar, M.3    Deacon, C.F.4    Torekov, S.S.5    Holst, J.J.6
  • 22
    • 55549136417 scopus 로고    scopus 로고
    • Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study
    • DeFronzo RA, Okerson T, Viswanathan P, Guan X, Holcombe JH, MacConell L. Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study. Curr Med Res Opin 2008; 24: 2943-2952.
    • (2008) Curr Med Res Opin , vol.24 , pp. 2943-2952
    • DeFronzo, R.A.1    Okerson, T.2    Viswanathan, P.3    Guan, X.4    Holcombe, J.H.5    MacConell, L.6
  • 24
    • 0034853485 scopus 로고    scopus 로고
    • Clinical review 135: The importance of β-cell failure in the development and progression of type 2 diabetes
    • Kahn SE. Clinical review 135: The importance of β-cell failure in the development and progression of type 2 diabetes. J Clin Endocrinol Metab 2001; 86: 4047-4058.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4047-4058
    • Kahn, S.E.1
  • 25
    • 27744541052 scopus 로고    scopus 로고
    • Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
    • Fehse F, Trautmann M, Holst JJ et al. Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab 2005; 90: 5991-5997.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5991-5997
    • Fehse, F.1    Trautmann, M.2    Holst, J.J.3
  • 26
    • 65949122087 scopus 로고    scopus 로고
    • One-year treatment with exenatide improves β-cell function, compared to insulin glargine, in metformin treated type 2 diabetes patients: a randomized, controlled trial
    • Bunck MC, Diamant M, Corner A et al. One-year treatment with exenatide improves β-cell function, compared to insulin glargine, in metformin treated type 2 diabetes patients: a randomized, controlled trial. Diabetes Care 2009; 32: 762-768.
    • (2009) Diabetes Care , vol.32 , pp. 762-768
    • Bunck, M.C.1    Diamant, M.2    Corner, A.3
  • 27
    • 80054090833 scopus 로고    scopus 로고
    • Effects of exenatide on measures of β-cell function after 3years in metformin-treated patients with type 2 diabetes
    • Bunck MC, Corner A, Eliasson B et al. Effects of exenatide on measures of β-cell function after 3years in metformin-treated patients with type 2 diabetes. Diabetes Care 2011; 34: 2041-2047.
    • (2011) Diabetes Care , vol.34 , pp. 2041-2047
    • Bunck, M.C.1    Corner, A.2    Eliasson, B.3
  • 28
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006; 368: 1696-1705.
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 29
    • 84860638209 scopus 로고    scopus 로고
    • The cardiovascular effects of GLP-1 receptor agonists
    • Okerson T, Chilton RJ. The cardiovascular effects of GLP-1 receptor agonists. Cardiovasc Ther 2012; 30: e146-e155.
    • (2012) Cardiovasc Ther , vol.30
    • Okerson, T.1    Chilton, R.J.2
  • 30
    • 79953073598 scopus 로고    scopus 로고
    • Pharmacotherapy: GLP-1 analogues and insulin: sound the wedding bells?
    • Nauck MA, Meier JJ. Pharmacotherapy: GLP-1 analogues and insulin: sound the wedding bells? Nat Rev Endocrinol 2011; 7: 193-195.
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 193-195
    • Nauck, M.A.1    Meier, J.J.2
  • 31
    • 56549107405 scopus 로고    scopus 로고
    • Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes
    • Linnebjerg H, Park S, Kothare PA et al. Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes. Regul Pept 2008; 151: 123-129.
    • (2008) Regul Pept , vol.151 , pp. 123-129
    • Linnebjerg, H.1    Park, S.2    Kothare, P.A.3
  • 32
    • 70350619609 scopus 로고    scopus 로고
    • Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study
    • Astrup A, Rossner S, Van Goal L et al. Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet 2009; 374: 1606-1616.
    • (2009) Lancet , vol.374 , pp. 1606-1616
    • Astrup, A.1    Rossner, S.2    Van Goal, L.3
  • 34
    • 84877620499 scopus 로고    scopus 로고
    • European Medicines Agency. Outcome of extension of indication application for for Victoza (liraglutide). Accessed 29 February 2012
    • European Medicines Agency. 2011. Outcome of extension of indication application for for Victoza (liraglutide). Available from URL: http://www.ema.europa.eu/docs/en_GB/document_library/Summary_of_opinion/human/001026/WC500112831.pdf. Accessed 29 February 2012.
    • (2011)
  • 35
    • 84877617177 scopus 로고    scopus 로고
    • European Medicines Agency. Levemir Product Information. Accessed 29 February 2012
    • European Medicines Agency. 2012. Levemir Product Information. Available from URL: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000528/WC500036662.pdf. Accessed 29 February 2012.
    • (2012)
  • 36
    • 77954579761 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 analog and insulin combination therapy in the management of adults with type 2 diabetes mellitus
    • Tzefos M, Olin JL. Glucagon-like peptide-1 analog and insulin combination therapy in the management of adults with type 2 diabetes mellitus. Ann Pharmacother 2010; 44: 1294-1300.
    • (2010) Ann Pharmacother , vol.44 , pp. 1294-1300
    • Tzefos, M.1    Olin, J.L.2
  • 37
    • 80052067058 scopus 로고    scopus 로고
    • Combining basal insulin analogs with glucagon-like peptide-1 mimetics
    • Perfetti R. Combining basal insulin analogs with glucagon-like peptide-1 mimetics. Diabetes Technol Ther 2011; 13: 873-881.
    • (2011) Diabetes Technol Ther , vol.13 , pp. 873-881
    • Perfetti, R.1
  • 38
    • 84872204257 scopus 로고    scopus 로고
    • The Association of British Clinical Diabetologists (ABCD) nationwide exenatide and liraglutide audits (Abstract 804)
    • Ryder REJ, Thong KY, Cull ML, Mills AP, Walton C. The Association of British Clinical Diabetologists (ABCD) nationwide exenatide and liraglutide audits (Abstract 804). Diabetologia 2011; 54(Suppl 1): S326.
    • (2011) Diabetologia , vol.54 , Issue.SUPPL. 1
    • Ryder, R.E.J.1    Thong, K.Y.2    Cull, M.L.3    Mills, A.P.4    Walton, C.5
  • 39
    • 82655162217 scopus 로고    scopus 로고
    • Use of once daily liraglutide in type 2 diabetes: clinical practice and experiences from combination with oral antidiabetic drugs or insulin (Abstract 1142-P)
    • Anholm C, Frandsen H, Højgaard-Hansen EC, Vestergaard H, Madsbad S. Use of once daily liraglutide in type 2 diabetes: clinical practice and experiences from combination with oral antidiabetic drugs or insulin (Abstract 1142-P). Diabetes 2011; 60: A314.
    • (2011) Diabetes , vol.60
    • Anholm, C.1    Frandsen, H.2    Højgaard-Hansen, E.C.3    Vestergaard, H.4    Madsbad, S.5
  • 40
    • 84858079439 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 (GLP-1) analogue combined with insulin reduces HbA1c and weight with low risk of hypoglycemia and high treatment satisfaction
    • Lind M, Jendle J, Torffvit O, Lager I. Glucagon-like peptide 1 (GLP-1) analogue combined with insulin reduces HbA1c and weight with low risk of hypoglycemia and high treatment satisfaction. Prim Care Diabetes 2012; 6: 41-46.
    • (2012) Prim Care Diabetes , vol.6 , pp. 41-46
    • Lind, M.1    Jendle, J.2    Torffvit, O.3    Lager, I.4
  • 41
    • 68649099986 scopus 로고    scopus 로고
    • Exenatide added to insulin therapy: a retrospective review of clinical practice over two years in an academic endocrinology outpatient setting
    • Yoon NM, Cavaghan MK, Brunelle RL, Roach P. Exenatide added to insulin therapy: a retrospective review of clinical practice over two years in an academic endocrinology outpatient setting. Clin Ther 2009; 31: 1511-1523.
    • (2009) Clin Ther , vol.31 , pp. 1511-1523
    • Yoon, N.M.1    Cavaghan, M.K.2    Brunelle, R.L.3    Roach, P.4
  • 43
    • 79959428521 scopus 로고    scopus 로고
    • Safety, efficacy and tolerability of exenatide in combination with insulin in the Association of British Clinical Diabetologists nationwide exenatide audit
    • Thong KY, Jose B, Sukumar N et al. Safety, efficacy and tolerability of exenatide in combination with insulin in the Association of British Clinical Diabetologists nationwide exenatide audit. Diabetes Obes Metab 2011; 13: 703-710.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 703-710
    • Thong, K.Y.1    Jose, B.2    Sukumar, N.3
  • 44
    • 84877623133 scopus 로고    scopus 로고
    • Clinical effectiveness of concomitant therapy with exenatide BID and basal insulin in patients with type 2 diabetes: a real-world analysis (Abstract P 1350). World Diabetes Congress. Dubai, United Arab Emirates: International Diabetes Federation
    • Pawaskar M, Li Q, Lee LJ, Reynolds M, Hoogwerf BJ. Clinical effectiveness of concomitant therapy with exenatide BID and basal insulin in patients with type 2 diabetes: a real-world analysis (Abstract P 1350). World Diabetes Congress. Dubai, United Arab Emirates: International Diabetes Federation, 2011.
    • (2011)
    • Pawaskar, M.1    Li, Q.2    Lee, L.J.3    Reynolds, M.4    Hoogwerf, B.J.5
  • 45
    • 84863230184 scopus 로고    scopus 로고
    • Combination therapy with insulin glargine and exenatide: real-world outcomes in patients with type 2 diabetes
    • Levin P, Wei W, Wang L et al. Combination therapy with insulin glargine and exenatide: real-world outcomes in patients with type 2 diabetes. Curr Med Res Opin 2012; 28: 439-446.
    • (2012) Curr Med Res Opin , vol.28 , pp. 439-446
    • Levin, P.1    Wei, W.2    Wang, L.3
  • 46
    • 84857531976 scopus 로고    scopus 로고
    • Clinical outcomes using long-term combination therapy with insulin glargine and exenatide in patients with type 2 diabetes
    • Levin PA, Mersey JH, Zhou S, Bromberger LA. Clinical outcomes using long-term combination therapy with insulin glargine and exenatide in patients with type 2 diabetes. Endocr Pract 2012; 18: 17-25.
    • (2012) Endocr Pract , vol.18 , pp. 17-25
    • Levin, P.A.1    Mersey, J.H.2    Zhou, S.3    Bromberger, L.A.4
  • 47
    • 77955915187 scopus 로고    scopus 로고
    • Exenatide therapy in insulin-treated type 2 diabetes and obesity
    • Nayak UA, Govindan J, Baskar V, Kalupahana D, Singh BM. Exenatide therapy in insulin-treated type 2 diabetes and obesity. QJM 2010; 103: 687-694.
    • (2010) QJM , vol.103 , pp. 687-694
    • Nayak, U.A.1    Govindan, J.2    Baskar, V.3    Kalupahana, D.4    Singh, B.M.5
  • 48
    • 84891629188 scopus 로고    scopus 로고
    • Marked improvement in glycemic control with exenatide (Byetta®) on addition to metformin, sulfonylurea and insulin glargine in type 2 diabetes mellitus (Abstract 2309-PO)
    • Phillips S, Gulbranson N, Kabadi U. Marked improvement in glycemic control with exenatide (Byetta®) on addition to metformin, sulfonylurea and insulin glargine in type 2 diabetes mellitus (Abstract 2309-PO). Diabetes 2011; 60: A614.
    • (2011) Diabetes , vol.60
    • Phillips, S.1    Gulbranson, N.2    Kabadi, U.3
  • 49
    • 77955680861 scopus 로고    scopus 로고
    • Exenatide replacing insulin in obese/overweight patients with type 2 diabetes; a district general hospital experience (Abstract P342)
    • Vithian K, Qureshi A, Chen B, Steer K. Exenatide replacing insulin in obese/overweight patients with type 2 diabetes; a district general hospital experience (Abstract P342). Diabet Med 2009; 24: 139-140.
    • (2009) Diabet Med , vol.24 , pp. 139-140
    • Vithian, K.1    Qureshi, A.2    Chen, B.3    Steer, K.4
  • 50
    • 0037715390 scopus 로고    scopus 로고
    • The management of the obese diabetic patient
    • Albu J, Raja-Khan N. The management of the obese diabetic patient. Prim Care 2003; 30: 465-491.
    • (2003) Prim Care , vol.30 , pp. 465-491
    • Albu, J.1    Raja-Khan, N.2
  • 51
    • 63449136676 scopus 로고    scopus 로고
    • Insulin management in overweight or obese type 2 diabetes patients: the role of insulin glargine
    • Davies M, Khunti K. Insulin management in overweight or obese type 2 diabetes patients: the role of insulin glargine. Diabetes Obes Metab 2008; 10(Suppl 2): 42-49.
    • (2008) Diabetes Obes Metab , vol.10 , Issue.SUPPL. 2 , pp. 42-49
    • Davies, M.1    Khunti, K.2
  • 52
    • 79551615182 scopus 로고    scopus 로고
    • Use of twice-daily exenatide in basal insulin-treated patients with type 2 diabetes: a randomized, controlled trial
    • Buse JB, Bergenstal RM, Glass LC et al. Use of twice-daily exenatide in basal insulin-treated patients with type 2 diabetes: a randomized, controlled trial. Ann Int Med 2011; 154: 103-112.
    • (2011) Ann Int Med , vol.154 , pp. 103-112
    • Buse, J.B.1    Bergenstal, R.M.2    Glass, L.C.3
  • 53
    • 84865979163 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia)
    • Seino Y, Min KW, Niemoeller E, Takami A. Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia). Diabetes Obes Metab 2012; 14: 910-917.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 910-917
    • Seino, Y.1    Min, K.W.2    Niemoeller, E.3    Takami, A.4
  • 54
    • 84891633836 scopus 로고    scopus 로고
    • Metformin+exenatide+basal insuiln vs metformin+placebo+basal insulin: reaching A1c <6.5% without weight-gain or serious hypoglycemia (Abstract 18-LB)
    • Riddle M, Ahmann A, Basu A, Aroda V, Ratner R. Metformin+exenatide+basal insuiln vs metformin+placebo+basal insulin: reaching A1c <6.5% without weight-gain or serious hypoglycemia (Abstract 18-LB). Diabetes 2010; 59.
    • (2010) Diabetes , vol.59
    • Riddle, M.1    Ahmann, A.2    Basu, A.3    Aroda, V.4    Ratner, R.5
  • 55
    • 84891624145 scopus 로고    scopus 로고
    • Once-daily basal insulin added to oral antihyperglycemic medications (OAMs) and exenatide (Ex) improves glycemic control in patients (Pts) with type 2 diabetes (T2D) (Abstract 19-LB)
    • Blevins TC, Arakaki RF, Liljenquist DR et al. Once-daily basal insulin added to oral antihyperglycemic medications (OAMs) and exenatide (Ex) improves glycemic control in patients (Pts) with type 2 diabetes (T2D) (Abstract 19-LB). Diabetes 2012; 59.
    • (2012) Diabetes , vol.59
    • Blevins, T.C.1    Arakaki, R.F.2    Liljenquist, D.R.3
  • 56
    • 84867301604 scopus 로고    scopus 로고
    • Efficacy and safety of insulin lispro protamine suspension versus insulin glargine added to oral antihyperglycaemic medications and exenatide in patients with type 2 diabetes (Abstract 979)
    • Arakaki RF, Blevins TC, Liljenquist DR et al. Efficacy and safety of insulin lispro protamine suspension versus insulin glargine added to oral antihyperglycaemic medications and exenatide in patients with type 2 diabetes (Abstract 979). Diabetologia 2010; 53: S390-S391.
    • (2010) Diabetologia , vol.53
    • Arakaki, R.F.1    Blevins, T.C.2    Liljenquist, D.R.3
  • 57
    • 84862903186 scopus 로고    scopus 로고
    • Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1C targets
    • DeVries JH, Bain SC, Rodbard HW et al. Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1C targets. Diabetes Care 2012; 35: 1446-1454.
    • (2012) Diabetes Care , vol.35 , pp. 1446-1454
    • DeVries, J.H.1    Bain, S.C.2    Rodbard, H.W.3
  • 58
    • 84861787873 scopus 로고    scopus 로고
    • Adding insulin determir (IDet) to liraglutide and metformin improves glycaemic controls with sustained weight reduction and low hypoglycaemia rate: 52week results (Abstract 73)
    • Bain SC, DeVries JH, Seufert J et al. Adding insulin determir (IDet) to liraglutide and metformin improves glycaemic controls with sustained weight reduction and low hypoglycaemia rate: 52week results (Abstract 73). Diabetologia 2011; 54: S37.
    • (2011) Diabetologia , vol.54
    • Bain, S.C.1    DeVries, J.H.2    Seufert, J.3
  • 59
    • 80052770164 scopus 로고    scopus 로고
    • A new type 2 diabetes treatment paradigm: sequential addition of liraglutide to metformin and then basal insulin detemir (Abstract 276-OR)
    • Rosenstock J, DeVries JH, Seufert J et al. A new type 2 diabetes treatment paradigm: sequential addition of liraglutide to metformin and then basal insulin detemir (Abstract 276-OR). Diabetes 2011; 60: A76.
    • (2011) Diabetes , vol.60
    • Rosenstock, J.1    DeVries, J.H.2    Seufert, J.3
  • 60
    • 84877616318 scopus 로고    scopus 로고
    • Treatment intensification with insulin detemir does not compromise liraglutide-associated improvements in cardiovascular risk markers (Abstract P 1359). World Diabetes Congress. Dubai, United Arab Emirates: International Diabetes Federation
    • Rodbard H, DeVries JH, Bain SC, et al. Treatment intensification with insulin detemir does not compromise liraglutide-associated improvements in cardiovascular risk markers (Abstract P 1359). World Diabetes Congress. Dubai, United Arab Emirates: International Diabetes Federation, 2011.
    • (2011)
    • Rodbard, H.1    DeVries, J.H.2    Bain, S.C.3
  • 61
    • 84877597623 scopus 로고    scopus 로고
    • Exenatide and insulin combination therapy in type 2 diabetes
    • Abstract 2280-PO).
    • Rachabattula H, Mukhtar RYA, Taylor PN, Robinson AM. Exenatide and insulin combination therapy in type 2 diabetes. Diabetes 2011; 60: A606(Abstract 2280-PO).
    • (2011) Diabetes , vol.60
    • Rachabattula, H.1    Mukhtar, R.Y.A.2    Taylor, P.N.3    Robinson, A.M.4
  • 62
    • 81255214568 scopus 로고    scopus 로고
    • Hypoglycemia in patients with type 2 diabetes using concomitant exenatide BID and long-acting insulin therapy
    • Pawaskar MD, Blickensderfer AL, Hoogwerf BJ, Quimbo R, Wade R. Hypoglycemia in patients with type 2 diabetes using concomitant exenatide BID and long-acting insulin therapy. J Med Econ 2011; 14: 705-708.
    • (2011) J Med Econ , vol.14 , pp. 705-708
    • Pawaskar, M.D.1    Blickensderfer, A.L.2    Hoogwerf, B.J.3    Quimbo, R.4    Wade, R.5
  • 63
    • 85071831500 scopus 로고    scopus 로고
    • Clinical characteristics and outcomes in patients with type 2 diabetes (T2D) adding insulin glargine to exenatide or exenatide to insulin glargine in a US managed care setting
    • Abstract 972-P).
    • Levin P, Wei W, Wang L, Damon D, Baser O. Clinical characteristics and outcomes in patients with type 2 diabetes (T2D) adding insulin glargine to exenatide or exenatide to insulin glargine in a US managed care setting. Diabetes 2011; 60: A266(Abstract 972-P).
    • (2011) Diabetes , vol.60
    • Levin, P.1    Wei, W.2    Wang, L.3    Damon, D.4    Baser, O.5
  • 64
    • 77954593244 scopus 로고    scopus 로고
    • Real world clinical experience with exenatide, a long term study on weight and A1C control
    • Abstract 572-P).
    • Christofides EA, Boyle PJ, Johnson MT. Real world clinical experience with exenatide, a long term study on weight and A1C control. Diabetes 2009; 58: A154(Abstract 572-P).
    • (2009) Diabetes , vol.58
    • Christofides, E.A.1    Boyle, P.J.2    Johnson, M.T.3
  • 65
    • 65949111736 scopus 로고    scopus 로고
    • Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: a retrospective cohort study
    • Noel RA, Braun DK, Patterson RE, Bloomgren G. Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: a retrospective cohort study. Diabetes Care 2009; 32: 834-838.
    • (2009) Diabetes Care , vol.32 , pp. 834-838
    • Noel, R.A.1    Braun, D.K.2    Patterson, R.E.3    Bloomgren, G.4
  • 68
    • 67649304917 scopus 로고    scopus 로고
    • Arnold Chan K. Use of a claims-based active drug safety surveillance system to assess the risk of acute pancreatitis with exenatide or sitagliptin compared to metformin or glyburide
    • Dore DD, Seeger JD. Arnold Chan K. Use of a claims-based active drug safety surveillance system to assess the risk of acute pancreatitis with exenatide or sitagliptin compared to metformin or glyburide. Curr Med Res Opin 2009; 25: 1019-1027.
    • (2009) Curr Med Res Opin , vol.25 , pp. 1019-1027
    • Dore, D.D.1    Seeger, J.D.2
  • 69
    • 84867212961 scopus 로고    scopus 로고
    • Relative risk of acute pancreatitis in initiators of exenatide twice daily compared with other anti-diabetic medication: a follow-up study
    • Wenten M, Gaebler JA, Hussein M et al. Relative risk of acute pancreatitis in initiators of exenatide twice daily compared with other anti-diabetic medication: a follow-up study. Diabet Med 2012; 29: 1412-1418.
    • (2012) Diabet Med , vol.29 , pp. 1412-1418
    • Wenten, M.1    Gaebler, J.A.2    Hussein, M.3
  • 70
    • 79954994764 scopus 로고    scopus 로고
    • A cohort study of acute pancreatitis in relation to exenatide use
    • Dore DD, Bloomgren GL, Wenten M et al. A cohort study of acute pancreatitis in relation to exenatide use. Diabetes Obes Metab 2011; 13: 559-566.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 559-566
    • Dore, D.D.1    Bloomgren, G.L.2    Wenten, M.3
  • 71
    • 79951704452 scopus 로고    scopus 로고
    • Acute pancreatitis in type 2 diabetes treated with exenatide or sitagliptin: a retrospective observational pharmacy claims analysis
    • Garg R, Chen W, Pendergrass M. Acute pancreatitis in type 2 diabetes treated with exenatide or sitagliptin: a retrospective observational pharmacy claims analysis. Diabetes Care 2010; 33: 2349-2354.
    • (2010) Diabetes Care , vol.33 , pp. 2349-2354
    • Garg, R.1    Chen, W.2    Pendergrass, M.3
  • 72
    • 79952260576 scopus 로고    scopus 로고
    • Diabetes mellitus, fasting glucose, and risk of cause-specific death
    • Seshasai SR, Kaptoge S, Thompson A et al. Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med 2011; 364: 829-841.
    • (2011) N Engl J Med , vol.364 , pp. 829-841
    • Seshasai, S.R.1    Kaptoge, S.2    Thompson, A.3
  • 73
  • 74
    • 79959559653 scopus 로고    scopus 로고
    • Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
    • Elashoff M. Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology 2011; 141: 150-156.
    • (2011) Gastroenterology , vol.141 , pp. 150-156
    • Elashoff, M.1
  • 75
    • 84877605121 scopus 로고    scopus 로고
    • Scottish Medicines Consortium. Exenatide, 5 micrograms & 10 micrograms, solution for injection, prefilled pen (Byetta®). Accessed 30 August 2012
    • Scottish Medicines Consortium. Exenatide, 5 micrograms & 10 micrograms, solution for injection, prefilled pen (Byetta®). Available from URL: http://www.scottishmedicines.org.uk/files/advice/exenatide_Byetta_FINAL_May_2012_for_website.pdf. Accessed 30 August 2012.
  • 76
    • 5344261712 scopus 로고    scopus 로고
    • The CORE Diabetes Model: Projecting long-term clinical outcomes, costs and cost-effectiveness of interventions in diabetes mellitus (types 1 and 2) to support clinical and reimbursement decision-making
    • Palmer AJ, Roze S, Valentine WJ et al. The CORE Diabetes Model: Projecting long-term clinical outcomes, costs and cost-effectiveness of interventions in diabetes mellitus (types 1 and 2) to support clinical and reimbursement decision-making. Curr Med Res Opin 2004; 20(Suppl 1): S5-S26.
    • (2004) Curr Med Res Opin , vol.20 , Issue.SUPPL. 1
    • Palmer, A.J.1    Roze, S.2    Valentine, W.J.3
  • 77
    • 61849098413 scopus 로고    scopus 로고
    • Should NICE's threshold range for cost per QALY be raised? Yes
    • Towse A. Should NICE's threshold range for cost per QALY be raised? Yes. BMJ 2009; 338: b181.
    • (2009) BMJ , vol.338
    • Towse, A.1
  • 78
    • 84863331401 scopus 로고    scopus 로고
    • GLP-1 based therapies: differential effects on fasting and postprandial glucose
    • Fineman MS, Cirincione BB, Maggs D, Diamant M. GLP-1 based therapies: differential effects on fasting and postprandial glucose. Diabetes Obes Metab 2012; 14: 675-688.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 675-688
    • Fineman, M.S.1    Cirincione, B.B.2    Maggs, D.3    Diamant, M.4
  • 79
    • 84877590982 scopus 로고    scopus 로고
    • Real world clinical experience with exenatide, a long term study on weight and A1c control
    • Abstract 2323-PO).
    • Houser D, Christofides E. Real world clinical experience with exenatide, a long term study on weight and A1c control. Diabetes 2011; 60: A618(Abstract 2323-PO).
    • (2011) Diabetes , vol.60
    • Houser, D.1    Christofides, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.