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Volumn 47, Issue 9, 2013, Pages 4104-4112

Phototransformation determines the fate of 5-fluorouracil and cyclophosphamide in natural surface waters

Author keywords

[No Author keywords available]

Indexed keywords

ATTENUATION PROCESS; DIRECT PHOTOLYSIS; PHOTOTRANSFORMATION PRODUCTS; PHOTOTRANSFORMATIONS; RISK TO HUMAN HEALTH; SYNTHETIC WATERS; TOTAL ORGANIC CARBON; WASTEWATER DISCHARGE;

EID: 84877623222     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es304976q     Document Type: Article
Times cited : (91)

References (48)
  • 1
    • 0031105636 scopus 로고    scopus 로고
    • Biological degradation of cyclophosphamide and its occurrence in sewage water
    • Steger-Hartmann, T.; Kümmerer, K.; Hartmann, A. Biological degradation of cyclophosphamide and its occurrence in sewage water Ecotoxicol. Environ. Safe. 1997, 36 (2) 174-179
    • (1997) Ecotoxicol. Environ. Safe. , vol.36 , Issue.2 , pp. 174-179
    • Steger-Hartmann, T.1    Kümmerer, K.2    Hartmann, A.3
  • 2
    • 33845284543 scopus 로고    scopus 로고
    • Occurrence and fate of the cytostatic drugs cyclophosphamide and ifosfamide in wastewater and surface waters
    • Buerge, I. J.; Buser, H.-R.; Poiger, T.; Müller, M. D. Occurrence and fate of the cytostatic drugs cyclophosphamide and ifosfamide in wastewater and surface waters Environ. Sci. Technol. 2006, 40 (23) 7242-7250
    • (2006) Environ. Sci. Technol. , vol.40 , Issue.23 , pp. 7242-7250
    • Buerge, I.J.1    Buser, H.-R.2    Poiger, T.3    Müller, M.D.4
  • 3
    • 73649096196 scopus 로고    scopus 로고
    • A preliminary study on the occurrence of cytostatic drugs in hospital effluents in Beijing, China
    • Yin, J.; Shao, B.; Zhang, J.; Li, K. A preliminary study on the occurrence of cytostatic drugs in hospital effluents in Beijing, China Bull. Environ. Contam. Toxicol. 2010, 84 (1) 39-45
    • (2010) Bull. Environ. Contam. Toxicol. , vol.84 , Issue.1 , pp. 39-45
    • Yin, J.1    Shao, B.2    Zhang, J.3    Li, K.4
  • 4
    • 0002837142 scopus 로고    scopus 로고
    • Trace analysis of the antineoplastics ifosfamide and cyclophosphamide in sewage water by twostep solid-phase extraction and gas chromatography-mass spectrometry
    • Steger-Hartmann, T.; Kümmerer, K.; Schecker, J. Trace analysis of the antineoplastics ifosfamide and cyclophosphamide in sewage water by twostep solid-phase extraction and gas chromatography-mass spectrometry J. Chromatogr., A 1996, 726 (1-2) 179-184
    • (1996) J. Chromatogr., A , vol.726 , Issue.12 , pp. 179-184
    • Steger-Hartmann, T.1    Kümmerer, K.2    Schecker, J.3
  • 5
    • 0034690742 scopus 로고    scopus 로고
    • Presence of therapeutic drugs in the environment
    • Zuccato, E.; Calamari, D.; Natangelo, M.; Fanelli, R. Presence of therapeutic drugs in the environment Lancet 2000, 355 (9217) 1789-1790
    • (2000) Lancet , vol.355 , Issue.9217 , pp. 1789-1790
    • Zuccato, E.1    Calamari, D.2    Natangelo, M.3    Fanelli, R.4
  • 6
    • 33750976959 scopus 로고    scopus 로고
    • Fate of 5-fluorouracil, doxorubicin, epirubicin, and daunorubicin in hospital wastewater and their elimination by activated sludge and treatment in a membrane-bio-reactor system
    • Mahnik, S.; Lenz, K.; Weissenbacher, N.; Mader, R.; Fuerhacker, M. Fate of 5-fluorouracil, doxorubicin, epirubicin, and daunorubicin in hospital wastewater and their elimination by activated sludge and treatment in a membrane-bio-reactor system Chemosphere 2007, 66 (1) 30-37
    • (2007) Chemosphere , vol.66 , Issue.1 , pp. 30-37
    • Mahnik, S.1    Lenz, K.2    Weissenbacher, N.3    Mader, R.4    Fuerhacker, M.5
  • 8
    • 68549086887 scopus 로고    scopus 로고
    • Development and validation of a sensitive and selective method using GC/MS-MS for quantification of 5-fluorouracil in hospital wastewater
    • Mullot, J.-U.; Karolak, S.; Fontova, A.; Huart, B.; Levi, Y. Development and validation of a sensitive and selective method using GC/MS-MS for quantification of 5-fluorouracil in hospital wastewater Anal. Bioanal. Chem. 2009, 394 (8) 2203-2212
    • (2009) Anal. Bioanal. Chem. , vol.394 , Issue.8 , pp. 2203-2212
    • Mullot, J.-U.1    Karolak, S.2    Fontova, A.3    Huart, B.4    Levi, Y.5
  • 9
    • 81755166687 scopus 로고    scopus 로고
    • Simultaneous determination of a selected group of cytostatic drugs in water using high-performance liquid chromatography-triple-quadrupole mass spectrometry
    • Martín, J.; Camacho-Muñoz, D.; Santos, J. L.; Aparicio, I.; Alonso, E. Simultaneous determination of a selected group of cytostatic drugs in water using high-performance liquid chromatography-triple-quadrupole mass spectrometry J. Sep. Sci. 2011, 34 (22) 3166-3177
    • (2011) J. Sep. Sci. , vol.34 , Issue.22 , pp. 3166-3177
    • Martín, J.1    Camacho-Muñoz, D.2    Santos, J.L.3    Aparicio, I.4    Alonso, E.5
  • 10
    • 0030739913 scopus 로고    scopus 로고
    • An alternative molecular mechanism of action of 5-fluorouracil, a potent anticancer drug
    • Ghoshal, K.; Jacob, S. T. An alternative molecular mechanism of action of 5-fluorouracil, a potent anticancer drug Biochem. Pharmacol. 1997, 53 (11) 1569-1575
    • (1997) Biochem. Pharmacol. , vol.53 , Issue.11 , pp. 1569-1575
    • Ghoshal, K.1    Jacob, S.T.2
  • 11
    • 84877618081 scopus 로고    scopus 로고
    • Bureau of National Health Insurance (BNHI), Department of Health, Executive Yuan, Republic of China, (.
    • Bureau of National Health Insurance (BNHI), Department of Health, Executive Yuan, Republic of China, (2005, http://www.nhi.gov.tw/english/.
    • (2005)
  • 12
    • 33750624076 scopus 로고    scopus 로고
    • Occurrence and biodegradability studies of selected pharmaceuticals and personal care products in sewage effluent
    • Yu, J. T.; Bouwer, E. J.; Coelhan, M. Occurrence and biodegradability studies of selected pharmaceuticals and personal care products in sewage effluent Agric. Water Manage. 2006, 86 (1-2) 72-80
    • (2006) Agric. Water Manage. , vol.86 , Issue.12 , pp. 72-80
    • Yu, J.T.1    Bouwer, E.J.2    Coelhan, M.3
  • 13
    • 0037369490 scopus 로고    scopus 로고
    • Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment
    • Andreozzi, R.; Raffaele, M.; Nicklas, P. Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment Chemosphere 2003, 50 (10) 1319-1330
    • (2003) Chemosphere , vol.50 , Issue.10 , pp. 1319-1330
    • Andreozzi, R.1    Raffaele, M.2    Nicklas, P.3
  • 14
    • 3242668650 scopus 로고    scopus 로고
    • Photochemical fate of sulfa drugs in the aquatic environment: Sulfa drugs containing five-membered heterocyclic groups
    • Boreen, A. L.; Arnold, W. A.; McNeill, K. Photochemical fate of sulfa drugs in the aquatic environment: Sulfa drugs containing five-membered heterocyclic groups Environ. Sci. Technol. 2004, 38 (14) 3933-3940
    • (2004) Environ. Sci. Technol. , vol.38 , Issue.14 , pp. 3933-3940
    • Boreen, A.L.1    Arnold, W.A.2    McNeill, K.3
  • 15
    • 20044371846 scopus 로고    scopus 로고
    • Photodegradation of the pharmaceuticals atorvastatin, carbamazepine, levofloxacin, and sulfamethoxazole in natural waters
    • Lam, M. W.; Mabury, S. A. Photodegradation of the pharmaceuticals atorvastatin, carbamazepine, levofloxacin, and sulfamethoxazole in natural waters Aquat. Sci. 2005, 67 (2) 177-188
    • (2005) Aquat. Sci. , vol.67 , Issue.2 , pp. 177-188
    • Lam, M.W.1    Mabury, S.A.2
  • 16
    • 18844379146 scopus 로고    scopus 로고
    • Photodegradation of common environmental pharmaceuticals and estrogens in river water
    • Lin, A. Y.-C.; Reinhard, M. Photodegradation of common environmental pharmaceuticals and estrogens in river water Environ. Toxicol. Chem. 2005, 24 (6) 1303-1309
    • (2005) Environ. Toxicol. Chem. , vol.24 , Issue.6 , pp. 1303-1309
    • Lin, A.Y.-C.1    Reinhard, M.2
  • 17
    • 0345921692 scopus 로고    scopus 로고
    • Photochemical fate of pharmaceuticals in the environment: Naproxen, diclofenac, clofibric acid, and ibuprofen
    • Packer, J. L.; Werner, J. J.; Latch, D. E.; McNeill, K.; Arnold, W. A. Photochemical fate of pharmaceuticals in the environment: Naproxen, diclofenac, clofibric acid, and ibuprofen Aquat. Sci. 2003, 65 (4) 342-351
    • (2003) Aquat. Sci. , vol.65 , Issue.4 , pp. 342-351
    • Packer, J.L.1    Werner, J.J.2    Latch, D.E.3    McNeill, K.4    Arnold, W.A.5
  • 18
  • 19
    • 0037445163 scopus 로고    scopus 로고
    • Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters
    • Tixier, C.; Singer, H. P.; Oellers, S.; Muller, S. R. Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters Environ. Sci. Technol. 2003, 37 (6) 1061-1068
    • (2003) Environ. Sci. Technol. , vol.37 , Issue.6 , pp. 1061-1068
    • Tixier, C.1    Singer, H.P.2    Oellers, S.3    Muller, S.R.4
  • 21
    • 0020329873 scopus 로고
    • Development and evaluation of sunlight actinometers
    • Dulin, D.; Mill, T. Development and evaluation of sunlight actinometers Environ. Sci. Technol. 1982, 16 (11) 815-820
    • (1982) Environ. Sci. Technol. , vol.16 , Issue.11 , pp. 815-820
    • Dulin, D.1    Mill, T.2
  • 22
    • 33947477789 scopus 로고
    • Thiation of nucleosides. IV. The synthesis of 5-fluoro-2′- deoxycytidine and related compounds
    • Wempen, I.; Duschinsky, R.; Kaplan, L.; Fox, J. J. Thiation of nucleosides. IV. The synthesis of 5-fluoro-2′-deoxycytidine and related compounds J. Am. Chem. Soc. 1961, 83 (23) 4755-4766
    • (1961) J. Am. Chem. Soc. , vol.83 , Issue.23 , pp. 4755-4766
    • Wempen, I.1    Duschinsky, R.2    Kaplan, L.3    Fox, J.J.4
  • 23
    • 0021039796 scopus 로고
    • Photochemical formation of hydrogen peroxide in surface and ground waters exposed to sunlight
    • Cooper, W. J.; Zika, R. G. Photochemical formation of hydrogen peroxide in surface and ground waters exposed to sunlight Science 1983, 220 (4598) 711-712
    • (1983) Science , vol.220 , Issue.4598 , pp. 711-712
    • Cooper, W.J.1    Zika, R.G.2
  • 24
    • 0032189288 scopus 로고    scopus 로고
    • Nitrate-induced photolysis in natural waters: Controls on concentrations of hydroxyl radical photo-intermediates by natural scavenging agents
    • Brezonik, P. L.; Fulkerson-Brekken, J. Nitrate-induced photolysis in natural waters: Controls on concentrations of hydroxyl radical photo-intermediates by natural scavenging agents Environ. Sci. Technol. 1998, 32 (19) 3004-3010
    • (1998) Environ. Sci. Technol. , vol.32 , Issue.19 , pp. 3004-3010
    • Brezonik, P.L.1    Fulkerson-Brekken, J.2
  • 25
    • 0033636704 scopus 로고    scopus 로고
    • Steady-state concentrations of carbonate radicals in field waters
    • Huang, J.; Mabury, S. A. Steady-state concentrations of carbonate radicals in field waters Environ. Toxicol. Chem. 2000, 19 (9) 2181-2188
    • (2000) Environ. Toxicol. Chem. , vol.19 , Issue.9 , pp. 2181-2188
    • Huang, J.1    Mabury, S.A.2
  • 26
    • 0023346158 scopus 로고
    • Nitrate-induced photooxidation of trace organic chemicals in water
    • Zepp, R. G.; Hoigne, J.; Bader, H. Nitrate-induced photooxidation of trace organic chemicals in water Environ. Sci. Technol. 1987, 21 (5) 443-450
    • (1987) Environ. Sci. Technol. , vol.21 , Issue.5 , pp. 443-450
    • Zepp, R.G.1    Hoigne, J.2    Bader, H.3
  • 28
    • 0023880840 scopus 로고
    • Reactivity of the carbonate radical with aniline derivatives
    • Larson, R. A.; Zepp, R. G. Reactivity of the carbonate radical with aniline derivatives Environ. Toxicol. Chem. 1988, 7 (4) 265-274
    • (1988) Environ. Toxicol. Chem. , vol.7 , Issue.4 , pp. 265-274
    • Larson, R.A.1    Zepp, R.G.2
  • 29
    • 0033103911 scopus 로고    scopus 로고
    • Predicting photoreaction rates in surface waters
    • Mill, T. Predicting photoreaction rates in surface waters Chemosphere 1999, 38 (6) 1379-1390
    • (1999) Chemosphere , vol.38 , Issue.6 , pp. 1379-1390
    • Mill, T.1
  • 30
    • 28444474518 scopus 로고    scopus 로고
    • Photosensitizer method to determine rate constants for the reaction of carbonate radical with organic compounds
    • Canonica, S.; Kohn, T.; Mac, M.; Real, F. J.; Wirz, J.; von Gunten, U. Photosensitizer method to determine rate constants for the reaction of carbonate radical with organic compounds Environ. Sci. Technol. 2005, 39 (23) 9182-9188
    • (2005) Environ. Sci. Technol. , vol.39 , Issue.23 , pp. 9182-9188
    • Canonica, S.1    Kohn, T.2    Mac, M.3    Real, F.J.4    Wirz, J.5    Von Gunten, U.6
  • 31
    • 79952984160 scopus 로고    scopus 로고
    • Photodegradation of 17β-estradiol in aquatic solution under solar irradiation: Kinetics and influencing water parameters
    • Chowdhury, R. R.; Charpentier, P. A.; Ray, M. B. Photodegradation of 17β-estradiol in aquatic solution under solar irradiation: Kinetics and influencing water parameters J. Photochem. Photobiol., A 2011, 219 (1) 67-75
    • (2011) J. Photochem. Photobiol., A , vol.219 , Issue.1 , pp. 67-75
    • Chowdhury, R.R.1    Charpentier, P.A.2    Ray, M.B.3
  • 32
    • 0037364665 scopus 로고    scopus 로고
    • PhotoFate: A new approach in accounting for the contribution of indirect photolysis of pesticides and pharmaceuticals in surface waters
    • Lam, M. W.; Tantuco, K.; Mabury, S. A. PhotoFate: A new approach in accounting for the contribution of indirect photolysis of pesticides and pharmaceuticals in surface waters Environ. Sci. Technol. 2003, 37 (5) 899-907
    • (2003) Environ. Sci. Technol. , vol.37 , Issue.5 , pp. 899-907
    • Lam, M.W.1    Tantuco, K.2    Mabury, S.A.3
  • 33
    • 0033881455 scopus 로고    scopus 로고
    • The role of carbonate radical in limiting the persistence of sulfur-containing chemicals in sunlit natural waters
    • Huang, J.; Mabury, S. A. The role of carbonate radical in limiting the persistence of sulfur-containing chemicals in sunlit natural waters Chemosphere 2000, 41 (11) 1775-1782
    • (2000) Chemosphere , vol.41 , Issue.11 , pp. 1775-1782
    • Huang, J.1    Mabury, S.A.2
  • 34
    • 84869441856 scopus 로고    scopus 로고
    • Phototransformation of cephalosporin antibiotics in an aqueous environment results in higher toxicity
    • Wang, X.-H.; Lin, A. Y.-C. Phototransformation of cephalosporin antibiotics in an aqueous environment results in higher toxicity Environ. Sci. Technol. 2012, 46 (22) 12417-12426
    • (2012) Environ. Sci. Technol. , vol.46 , Issue.22 , pp. 12417-12426
    • Wang, X.-H.1    Lin, A.Y.-C.2
  • 35
    • 0002464079 scopus 로고    scopus 로고
    • Photochemistry of nitrite and nitrate in aqueous solution: A review
    • Mack, J.; Bolton, J. R. Photochemistry of nitrite and nitrate in aqueous solution: A review J. Photochem. Photobiol., A 1999, 128 (1-3) 1-13
    • (1999) J. Photochem. Photobiol., A , vol.128 , Issue.13 , pp. 1-13
    • MacK, J.1    Bolton, J.R.2
  • 36
    • 33847090166 scopus 로고
    • Laser photolysis studies of duroquinone triplet state electron transfer reactions
    • Scheerer, R.; Graetzel, M. Laser photolysis studies of duroquinone triplet state electron transfer reactions J. Am. Chem. Soc. 1977, 99 (3) 865-871
    • (1977) J. Am. Chem. Soc. , vol.99 , Issue.3 , pp. 865-871
    • Scheerer, R.1    Graetzel, M.2
  • 37
    • 0026507759 scopus 로고
    • Effects of carbonates on the aquatic photodegradation rate of bromoxynil (3,5-dibromo-4-hydroxybenzonttrile) herbicide
    • Kochany, J. Effects of carbonates on the aquatic photodegradation rate of bromoxynil (3,5-dibromo-4-hydroxybenzonttrile) herbicide Chemosphere 1992, 24 (8) 1119-1126
    • (1992) Chemosphere , vol.24 , Issue.8 , pp. 1119-1126
    • Kochany, J.1
  • 38
    • 0017871183 scopus 로고
    • Thermal and photolytic decomposition of methotrexate in aqueous solutions
    • Chatterji, D. C.; Gallelli, J. F. Thermal and photolytic decomposition of methotrexate in aqueous solutions J. Pharm. Sci. 1978, 67 (4) 526-531
    • (1978) J. Pharm. Sci. , vol.67 , Issue.4 , pp. 526-531
    • Chatterji, D.C.1    Gallelli, J.F.2
  • 39
    • 0000582243 scopus 로고    scopus 로고
    • Trace enrichment, chromatographic separation and biodegradation of cytostatic compounds in surface water
    • Kiffmeyer, T.; Götze, H.-J.; Jursch, M.; Lüders, U. Trace enrichment, chromatographic separation and biodegradation of cytostatic compounds in surface water Fresenius' J. Aanl. Chem. 1998, 361 (2) 185-191-191
    • (1998) Fresenius' J. Aanl. Chem. , vol.361 , Issue.2 , pp. 185-191
    • Kiffmeyer, T.1    Götze, H.-J.2    Jursch, M.3    Lüders, U.4
  • 40
    • 0031295578 scopus 로고    scopus 로고
    • Biodegradability of the anti-tumour agents 5-fluorouracil, cytarabine, and gemcitabine: Impact of the chemical structure and synergistic toxicity with hospital effluent
    • Kümmerer, K.; Al-Ahmad, A. Biodegradability of the anti-tumour agents 5-fluorouracil, cytarabine, and gemcitabine: Impact of the chemical structure and synergistic toxicity with hospital effluent Acta Hydrochim. Hydrobiol. 1997, 25 (4) 166-172
    • (1997) Acta Hydrochim. Hydrobiol. , vol.25 , Issue.4 , pp. 166-172
    • Kümmerer, K.1    Al-Ahmad, A.2
  • 42
    • 84877610875 scopus 로고    scopus 로고
    • U.S. National Library of Medicine.
    • U.S. National Library of Medicine. http://www.nlm.nih.gov/.
  • 43
    • 84877600106 scopus 로고    scopus 로고
    • California Irrigation Management Information System (CIMIS).
    • California Irrigation Management Information System (CIMIS). http://wwwcimis.water.ca.gov/cimis/welcome.jsp.
  • 44
    • 0018885426 scopus 로고
    • Pharmacokinetics of 5-fluorouracil administered orally, by rapid intravenous and by slow infusion
    • Fraile, R. J.; Baker, L. H.; Buroker, T. R.; Horwitz, J.; Vaitkevicius, V. K. Pharmacokinetics of 5-fluorouracil administered orally, by rapid intravenous and by slow infusion Cancer Res. 1980, 40 (7) 2223-2228
    • (1980) Cancer Res. , vol.40 , Issue.7 , pp. 2223-2228
    • Fraile, R.J.1    Baker, L.H.2    Buroker, T.R.3    Horwitz, J.4    Vaitkevicius, V.K.5
  • 45
    • 77449118980 scopus 로고    scopus 로고
    • Estimation of the cancer risk to humans resulting from the presence of cyclophosphamide and ifosfamide in surface water
    • Kümmerer, K.; Al-Ahmad, A. Estimation of the cancer risk to humans resulting from the presence of cyclophosphamide and ifosfamide in surface water Environ. Sci. Pollut. Res. 2010, 17 (2) 486-496
    • (2010) Environ. Sci. Pollut. Res. , vol.17 , Issue.2 , pp. 486-496
    • Kümmerer, K.1    Al-Ahmad, A.2
  • 46
    • 58249116903 scopus 로고    scopus 로고
    • Challenge of high polarity and low concentrations in analysis of cytostatics and metabolites in wastewater by hydrophilic interaction chromatography/tandem mass spectrometry
    • Kovalova, L.; McArdell, C. S.; Hollender, J. Challenge of high polarity and low concentrations in analysis of cytostatics and metabolites in wastewater by hydrophilic interaction chromatography/tandem mass spectrometry J. Chromatogr., A 2009, 1216 (7) 1100-1108
    • (2009) J. Chromatogr., A , vol.1216 , Issue.7 , pp. 1100-1108
    • Kovalova, L.1    McArdell, C.S.2    Hollender, J.3
  • 48
    • 84877630272 scopus 로고    scopus 로고
    • Taiwan Water Supply Corporation, (.
    • Taiwan Water Supply Corporation, (2012, http://www.water.gov.tw/eng/ index.asp.
    • (2012)


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