Effect of eicosapentaenoic acid-derived prostaglandin E3 on intestinal epithelial barrier function

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 88, Issue 5, 2013, Pages 339-345

  Rodríguez Lagunas, Maria J ^a   Ferrer, Ruth ^a   Moreno, Juan J ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Caco 2 cells; Inflammatory bowel disease; Paracellular permeability; PGE3

Indexed keywords

CALCIUM ION; CLAUDIN 4; CYCLIC AMP; DEXTRAN; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OCCLUDIN; PROSTAGLANDIN E RECEPTOR 1; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; PROSTAGLANDIN E3;

ARTICLE; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL MEMBRANE PERMEABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTRIC RESISTANCE; ENZYME ACTIVATION; IMMUNOFLUORESCENCE; INTESTINAL EPITHELIAL BARRIER FUNCTION; INTESTINE EPITHELIUM CELL; INTESTINE FUNCTION; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING;

ALPROSTADIL; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; DINOPROSTONE; EICOSAPENTAENOIC ACID; HUMANS; INTESTINAL MUCOSA;

EID: 84877606473     PISSN: 09523278     EISSN: 15322823     Source Type: Journal    
DOI: 10.1016/j.plefa.2013.02.001     Document Type: Article

References (49)

1. Herschman H.R. Prostaglandin synthase 2. Biochim. Biophys. Acta 1996, 1299:125-140.
2. Lands W.E., Libelt B., Morris A., Kramer N.C., Prewitt T.E., Bowen P., et al. Maintenance of lower proportions of (n-6) eicosanoid precursors in phospholipids of human plasma in response to added dietary (n-3) fatty acids. Biochim. Biophys. Acta 1992, 1180:147-162.
3. Smith W.L. Cyclooxygenases, peroxide tone and the allure of fish oil. Curr. Opin. Cell Biol. 2005, 17:174-182.
4. Hansen H.S. Dietary essential fatty acids and in vivo prostaglandin production in mammals. World Rev. Nutr. Diet 1983, 42:102-134.
5. Calder P.C. N-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am. J. Clin. Nutr. 2006, 83:1505S-1519SS.
6. 3 alpha are excreted in human urine after ingestion of n-3 polyunsaturated fatty acids. Biochim. Biophys. Acta 1988, 963:501-508.
7. Connor W.E. Importance of n-3 fatty acids in health and disease. Am. J. Clin. Nutr. 2000, 71:171S-175SS.
8. Mitic L.L., Anderson J.M. Molecular architecture of tight junctions. Annu. Rev. Physiol. 1998, 60:121-142.
9. Shin K., Fogg V.C., Margolis B. Tight junctions and cell polarity. Annu. Rev. Cell Dev. Biol. 2006, 22:207-235.
10. Turner J.R. Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application. Am. J. Pathol. 2006, 169:1901-1909.
11. Rampton D.S., Hawkey C.J. Prostaglandins and ulcerative colitis. Gut 1984, 25:1399-1413.
12. Calder P.C. Polyunsaturated fatty acids, inflammatory processes and inflammatory bowel diseases. Mol. Nutr. Food Res. 2008, 52:885-897.
13. 4 receptors in Caco-2 cell monolayers. Am. J. Physiol. Cell Physiol. 2010, 299:C324-C334.
14. Martin-Venegas R., Roig-Perez S., Ferrer R., Moreno J.J. Arachidonic acid cascade and epithelial barrier function during Caco-2 cell differentiation. J. Lipid Res. 2006, 47:1416-1423.
15. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 1985, 260:3440-3450.
16. Watanabe K., Kawamori T., Nakatsugi S., Ohta T., Ohuchida S., Yamamoto H., et al. Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis. Cancer Res. 1999, 59:5093-5096.
17. Davis T.L., Sharif N.A. Pharmacological characterization of [(3)H]-prostaglandin E(2) binding to the cloned human EP(4) prostanoid receptor. Br. J. Pharmacol. 2000, 130:1919-1926.
18. 3 signaling regulates tumor-associated angiogenesis and tumor growth. J. Exp. Med. 2003, 197:221-232.
19. Gonzalez-Mariscal L., Tapia R., Chamorro D. Crosstalk of tight junction components with signaling pathways. Biochim. Biophys. Acta 2008, 1778:729-756.
20. Smith R.J., Sam L.M., Justen J.M., Bundy G.L., Bala G.A., Bleasdale J.E. Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness. J. Pharmacol. Exp. Ther. 1990, 253:688-697.
21. Van Winkle W.B. Calcium release from skeletal muscle sarcoplasmic reticulum: site of action of dantrolene sodium. Science 1976, 193:1130-1131.
22. Ma T.Y., Iwamoto G.K., Hoa N.T., Akotia V., Pedram A., Boivin M.A., et al. TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation. Am. J. Physiol. Gastrointestine Liver Physiol. 2004, 286:G367-G376.
23. Clayburgh D.R., Shen L., Turner J.R. A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest. 2004, 84:282-291.
24. Boughton-Smith N.K., Hawkey C.J., Whittle B.J. Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa. Gut 1983, 24:1176-1182.
25. Eberhart C.E., Dubois R.N. Eicosanoids and the gastrointestinal tract. Gastroenterology 1995, 109:285-301.
26. Krimsky M., Yedgar S., Aptekar L., Schwob O., Goshen G., Gruzman A., et al. Amelioration of TNBS-induced colon inflammation in rats by phospholipase A2 inhibitor. Am. J. Physiol. Gastrointest. Liver Physiol. 2003, 285:G586-G592.
27. Bagga D., Wang L., Farias-Eisner R., Glaspy J.A., Reddy S.T. Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion. Proc. Natl. Acad. Sci. USA 2003, 100:1751-1756.
28. Willemsen L.E., Koetsier M.A., Balvers M., Beermann C., Stahl B., van Tol E.A. Polyunsaturated fatty acids support epithelial barrier integrity and reduce IL-4 mediated permeability in vitro. Eur. J. Nutr. 2008, 47:183-191.
29. Roig-Perez S., Guardiola F., Moreto M., Ferrer R. Lipid peroxidation induced by DHA enrichment modifies paracellular permeability in Caco-2 cells: protective role of taurine. J. Lipid Res. 2004, 45:1418-1428.
30. Usami M., Komurasaki T., Hanada A., Kinoshita K., Ohata A. Effect of gamma-linolenic acid or docosahexaenoic acid on tight junction permeability in intestinal monolayer cells and their mechanism by protein kinase C activation and/or eicosanoid formation. Nutrition 2003, 19:150-156.
31. Usami M., Muraki K., Iwamoto M., Ohata A., Matsushita E., Miki A. Effect of eicosapentaenoic acid (EPA) on tight junction permeability in intestinal monolayer cells. Clin. Nutr. 2001, 20:351-359.
32. Roig-Perez S., Cortadellas N., Moreto M., Ferrer R. Intracellular mechanisms involved in docosahexaenoic acid-induced increases in tight junction permeability in Caco-2 cell monolayers. J. Nutr. 2010, 140:1557-1563.
33. Moreno J.J. Differential effects of arachidonic and eicosapentaenoic acid-derived eicosanoids on polymorphonuclear transmigration across endothelial cell cultures. J. Pharmacol. Exp. Ther. 2009, 331:1111-1117.
34. Alexander J.W. Immunonutrition: the role of omega-3 fatty acids. Nutrition 1998, 14:627-633.
35. Lindmark T., Kimura Y., Artursson P. Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells. J. Pharmacol. Exp. Ther. 1998, 284:362-369.
36. Al-Sadi R. Mechanism of cytokine modulation of epithelial tight junction barrier. Front. Biosci. 2009, 14:2765.
37. Harhaj N.S., Antonetti D.A. Regulation of tight junctions and loss of barrier function in pathophysiology. Int. J. Biochem. Cell Biol. 2004, 36:1206-1237.
38. Bruewer M., Luegering A., Kucharzik T., Parkos C.A., Madara J.L., Hopkins A.M., et al. Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms. J. Immunol. 2003, 171:6164-6172.
39. Ma T.Y., Nguyen D., Bui V., Nguyen H., Hoa N. Ethanol modulation of intestinal epithelial tight junction barrier. Am. J. Physiol. 1999, 276:G965-G974.
40. Ma T.Y., Tran D., Hoa N., Nguyen D., Merryfield M., Tarnawski A. Mechanism of extracellular calcium regulation of intestinal epithelial tight junction permeability: role of cytoskeletal involvement. Microsci. Res. Tech. 2000, 51:156-168.
41. Schwarz B.T., Wang F., Shen L., Clayburgh D.R., Su L., Wang Y., et al. LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. Gastroenterology 2007, 132:2383-2394.
42. Al-Sadi R., Ye D., Dokladny K., Ma T.Y. Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. J. Immunol. 2008, 180:5653-5661.
43. Ohata A., Usami M., Miyoshi M. Short-chain fatty acids alter tight junction permeability in intestinal monolayer cells via lipoxygenase activation. Nutrition 2005, 21:838-847.
44. Shen L., Black E.D., Witkowski E.D., Lencer W.I., Guerriero V., Schneeberger E.E., et al. Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. J. Cell Sci. 2006, 119:2095-2106.
45. Ye D., Ma I., Ma T.Y. Molecular mechanism of tumor necrosis factor-alpha modulation of intestinal epithelial tight junction barrier. Am. J. Physiol. Gastrointestine Liver Physiol. 2006, 290:G496-G504.
46. Blair S.A., Kane S.V., Clayburgh D.R., Turner J.R. Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease. Lab Invest. 2006, 86:191-201.
47. Amasheh S., Fromm M., Gunzel D. Claudins of intestine and nephron-a correlation of molecular tight junction structure and barrier function. Acta Physiol. (Oxf) 2011, 201:133-140.
48. 2 produced by Entamoeba histolytica signals via EP4 receptor and alters claudin-4 to increase ion permeability of tight junctions. Am. J. Pathol. 2011, 179:807-818.
49. Takehara M., Nishimura T., Mima S., Hoshino T., Mizushima T. Effect of claudin expression on paracellular permeability, migration and invasion of colonic cancer cells. Biol. Pharm. Bull. 2009, 32:825-831.