Association between sex hormones, glucose homeostasis, adipokines, and inflammatory markers and mammographic density among postmenopausal women

Breast Cancer Research and Treatment

Volumn 139, Issue 1, 2013, Pages 255-265

  Woolcott, Christy G ^a   Courneya, Kerry S ^b   Boyd, Norman F ^c   Yaffe, Martin J ^d   McTiernan, Anne ^e   Brant, Rollin ^f   Jones, Charlotte A ^g   Stanczyk, Frank Z ^h   Terry, Tim ⁱ   Cook, Linda S ^j,k   Wang, Qinggang ^k   Friedenreich, Christine M ^k  

^a DALHOUSIE UNIVERSITY   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d Institute of Clinical Evaluative Sciences   (Canada)

^e Fred Hutchinson Cancer Research Center   (United States)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^g UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^h UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

ⁱ CROSS CANCER INSTITUTE   (Canada)

^j UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^k ALBERTA HEALTH SERVICES   (Canada)

more..

Author keywords

Adipokines; Breast neoplasms; Glucose homeostasis; Inflammation; Mammographic density; Steroid hormones

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; ANDROSTENEDIONE; C REACTIVE PROTEIN; ESTRADIOL; ESTRONE; GLUCOSE; INSULIN; INTERLEUKIN 6; LEPTIN; SEX HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; TUMOR NECROSIS FACTOR ALPHA;

ADIPOSE TISSUE; ADULT; AGED; ARTICLE; BLOOD SAMPLING; BODY MASS; BREAST CANCER; CANCER RISK; CORRELATION ANALYSIS; DIET RESTRICTION; DISEASE ASSOCIATION; FEMALE; GLUCOSE HOMEOSTASIS; HUMAN; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MAMMOGRAPHY; OBESITY; POSTMENOPAUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); WAIST CIRCUMFERENCE;

ADIPOKINES; ADIPOSITY; AGED; BLOOD GLUCOSE; BREAST; BREAST NEOPLASMS; FEMALE; GONADAL STEROID HORMONES; HOMEOSTASIS; HUMANS; INFLAMMATION; MAMMARY GLANDS, HUMAN; MIDDLE AGED; POSTMENOPAUSE; RADIOIMMUNOASSAY;

EID: 84877580988     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-013-2534-x     Document Type: Article

References (56)

1. McCormack VA, dos Santos Silva I (2006) Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis. Cancer Epidemiol Biomarkers Prev 15(6):1159-1169
2. Boyd NF, Rommens JM, Vogt K et al (2005) Mammographic breast density as an intermediate phenotype for breast cancer. Lancet Oncol 6(10):798-808
3. Martin LJ, Boyd NF (2008) Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: hypotheses based on epidemiological evidence. Breast Cancer Res 10(1):201
4. McTiernan A, Martin CF, Peck JD et al (2005) Estrogen-plus-progestin use and mammographic density in postmenopausal women: women's health initiative randomized trial. J Natl Cancer Inst 97(18):1366-1376
5. Greendale GA, Reboussin BA, Slone S et al (2003) Postmenopausal hormone therapy and change in mammographic density. J Natl Cancer Inst 95(1):30-37
6. Martin LJ, Minkin S, Boyd NF (2009) Hormone therapy, mammographic density, and breast cancer risk. Maturitas 64(1):20-26
7. Boyd NF, Stone J, Martin LJ et al (2002) The association of breast mitogens with mammographic densities. Br J Cancer 87(8):876-882
8. Bremnes Y, Ursin G, Bjurstam N et al (2007) Endogenous sex hormones, prolactin and mammographic density in postmenopausal Norwegian women. Int J Cancer 121(11):2506-2511
9. Tamimi RM, Hankinson SE, Colditz GA, Byrne C (2005) Endogenous sex hormone levels and mammographic density among postmenopausal women. Cancer Epidemiol Biomarkers Prev 14(11 Pt 1):2641-2647
10. Verheus M, Peeters PH, van Noord PA et al (2007) No relationship between circulating levels of sex steroids and mammographic breast density: the Prospect-EPIC cohort. Breast Cancer Res 9(4):R53
11. Warren R, Skinner J, Sala E et al (2006) Associations among mammographic density, circulating sex hormones, and polymorphisms in sex hormone metabolism genes in postmenopausal women. Cancer Epidemiol Biomarkers Prev 15(8):1502-1508
12. Sprague BL, Trentham-Dietz A, Gangnon RE et al (2011) Circulating sex hormones and mammographic breast density among postmenopausal women. Horm Cancer 2(1):62-72
13. McCormack VA, Dowsett M, Folkerd E et al (2009) Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women. Breast Cancer Res 11(3):R38
14. Johansson H, Gandini S, Bonanni B et al (2007) Relationships between circulating hormone levels, mammographic percent density and breast cancer risk factors in postmenopausal women. Breast Cancer Res Treat 108(1):57-67
15. Greendale GA, Palla SL, Ursin G et al (2005) The association of endogenous sex steroids and sex steroid binding proteins with mammographic density: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density Study. Am J Epidemiol 162(9):826-834
16. Aiello EJ, Tworoger SS, Yasui Y et al (2005) Associations among circulating sex hormones, insulin-like growth factor, lipids, and mammographic density in postmenopausal women. Cancer Epidemiol Biomarkers Prev 14(6):1411-1417
17. Stuedal A, Ursin G, Veierod MB et al (2006) Plasma levels of leptin and mammographic density among postmenopausal women: a cross-sectional study. Breast Cancer Res 8(5):R55
18. Reeves KW, Weissfeld JL, Modugno F, Diergaarde B (2011) Circulating levels of inflammatory markers and mammographic density among postmenopausal women. Breast Cancer Res Treat 127(2):555-563
19. Haars G, van Noord PA, van Gils CH et al (2005) Measurements of breast density: no ratio for a ratio. Cancer Epidemiol Biomarkers Prev 14(11 Pt 1):2634-2640
20. Friedenreich CM, Woolcott CG, McTiernan A et al (2010) The Alberta physical activity and breast cancer prevention trial: sex hormone changes in a year-long exercise intervention among postmenopausal women. J Clin Oncol 28:1458-1466
21. Friedenreich C, Neilson HK, Woolcott CG et al (2011) Alberta physical activity and breast cancer prevention trial: inflammatory marker changes in a year-long exercise intervention among postmenopausal women. Cancer Prev Res (Phila) 5(1):98-108
22. Friedenreich CM, Neilson HK, Woolcott CG et al (2011) Changes in insulin resistance indicators, IGFs, and adipokines in a year-long trial of aerobic exercise in postmenopausal women. Endocr Relat Cancer 18(3):357-369
23. Woolcott CG, Courneya KS, Boyd NF et al (2010) Mammographic density change with 1 year of aerobic exercise among postmenopausal women: a randomized controlled trial. Cancer Epidemiol Biomarkers Prev 19(4):1112-1121
24. Boyd N, Martin L, Gunasekara A et al (2009) Mammographic density and breast cancer risk: evaluation of a novel method of measuring breast tissue volumes. Cancer Epidemiol Biomarkers Prev 18(6):1754-1762
25. Stanczyk FZ, Lee JS, Santen RJ (2007) Standardization of steroid hormone assays: why, how, and when? Cancer Epidemiol Biomarkers Prev 16(9):1713-1719
26. Goebelsmann U, Horton R, Mestman JH et al (1973) Male pseudohermaphroditism due to testicular 17-hydroxysteroid dehydrogenase deficiency. J Clin Endocrinol Metab 36(5):867-879
27. Stanczyk FZ, Slater CC, Ramos DE et al (2009) Pharmacokinetics of dehydroepiandrosterone and its metabolites after long-term oral dehydroepiandrosterone treatment in postmenopausal women. Menopause 16(2):272-278
28. Rinaldi S, Geay A, Dechaud H et al (2002) Validity of free testosterone and free estradiol determinations in serum samples from postmenopausal women by theoretical calculations. Cancer Epidemiol Biomarkers Prev 11(10 Pt 1):1065-1071
29. Vermeulen A, Verdonck L, Kaufman JM (1999) A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 84(10):3666-3672
30. Byng JW, Boyd NF, Fishell E et al (1994) The quantitative analysis of mammographic densities. Phys Med Biol 39:1629-1638
31. Pawluczyk O, Augustine BJ, Yaffe MJ et al (2003) A volumetric method for estimation of breast density on digitized screen-film mammograms. Med Phys 30(3):352-364
32. Yaffe MJ (2008) Measurement of mammographic density. Breast Cancer Res 10(3):209
33. Diet History Questionnaire: Canadian version (2006). http://www. riskfactor.cancer.gov/DHQ/forms/canadian/index.html. Accessed 15 April 2013
34. National Cancer Institute, Risk Factor Monitoring and Methods Branch Division of Cancer Control and Population Sciences. Diet History Questionnaire (DHQ) (2002). http://www.riskfactor.cancer.gov/DHQ/forms/files/shared/dhq1.2007. sample.pdf. Accessed 15 April 2013
35. Woolcott CG, Cook LS, Courneya KS et al (2010) Associations of overall and abdominal adiposity with area and volumetric mammographic measures among postmenopausal women. Int J Cancer 129(2):440-448
36. Khandekar MJ, Cohen P, Spiegelman BM (2011) Molecular mechanisms of cancer development in obesity. Nat Rev Cancer 11(12):886-895
37. Endogenous Hormones and Breast Cancer Collaborative Group (2003) Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J Natl Cancer Inst 95(16):1218-1226
38. Vachon CM, Brandt KR, Ghosh K et al (2007) Mammographic breast density as a general marker of breast cancer risk. Cancer Epidemiol Biomarkers Prev 16(1):43-49
39. Verheus M, Peeters PH, Kaaks R et al (2007) Premenopausal insulin-like growth factor-I serum levels and changes in breast density over menopause. Cancer Epidemiol Biomarkers Prev 16(3):451-457
40. Martin LJ, Greenberg CV, Kriukov V et al (2009) Effect of a low-fat, high-carbohydrate dietary intervention on change in mammographic density over menopause. Breast Cancer Res Treat 113(1):163-172
41. Haakensen VD, Biong M, Lingjaerde OC et al (2010) Expression levels of uridine 5′-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density. Breast Cancer Res 12(4):R65
42. Edlefsen KL, Jackson RD, Prentice RL et al (2010) The effects of postmenopausal hormone therapy on serum estrogen, progesterone, and sex hormone-binding globulin levels in healthy postmenopausal women. Menopause 17(3):622-629
43. McTiernan A, Chlebowski RT, Martin C et al (2009) Conjugated equine estrogen influence on mammographic density in postmenopausal women in a substudy of the Women's Health Initiative randomized trial. J Clin Oncol 27(36):6135-6143
44. Conroy SM, Butler LM, Harvey D et al (2011) Metabolic syndrome and mammographic density: the Study of Women's Health Across the Nation. Int J Cancer 129(7):1699-1707
45. Sellers TA, Jensen LE, Vierkant RA et al (2007) Association of diabetes with mammographic breast density and breast cancer in the Minnesota breast cancer family study. Cancer Causes Control 18(5):505-515
46. Diorio C, Pollak M, Byrne C et al (2005) Levels of C-peptide and mammographic breast density. Cancer Epidemiol Biomarkers Prev 14(11 Pt 1):2661-2664
47. Hankinson SE, Willett WC, Manson JE et al (1998) Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women. J Natl Cancer Inst 90(17):1292-1299
48. Gunter MJ, Hoover DR, Yu H et al (2009) Insulin, insulin-like growth factor-I, and risk of breast cancer in postmenopausal women. J Natl Cancer Inst 101(1):48-60
49. Maskarinec G, Woolcott C, Steude JS et al (2010) The relation of leptin and adiponectin with breast density among premenopausal women. Eur J Cancer Prev 19(1):55-60
50. Furberg AS, Jasienska G, Bjurstam N et al (2005) Metabolic and hormonal profiles: HDL cholesterol as a plausible biomarker of breast cancer risk. The Norwegian EBBA Study. Cancer Epidemiol Biomarkers Prev 14(1):33-40
51. Macis D, Gandini S, Guerrieri-Gonzaga A et al (2012) Prognostic effect of circulating adiponectin in a randomized 2 × 2 trial of low-dose Tamoxifen and Fenretinide in premenopausal women at risk for breast cancer. J Clin Oncol 30(2):151-157
52. Heikkila K, Harris R, Lowe G et al (2009) Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysis. Cancer Causes Control 20(1):15-26
53. McTiernan A, Wang CY, Sorensen B et al (2009) No effect of aspirin on mammographic density in a randomized controlled clinical trial. Cancer Epidemiol Biomarkers Prev 18(5):1524-1530
54. Terry MB, Buist DS, Trentham-Dietz A et al (2008) Nonsteroidal anti-inflammatory drugs and change in mammographic density: a cohort study using pharmacy records on over 29,000 postmenopausal women. Cancer Epidemiol Biomarkers Prev 17(5):1088-1095
55. Maskarinec G, Urano Y, Gill J, Kolonel LN (2008) Nonsteroidal anti-inflammatory drugs (NSAIDs) and mammographic density. Breast Cancer Res Treat 112(1):133-139
56. Yang WT, Lewis MT, Hess K et al (2010) Decreased TGF beta signaling and increased COX2 expression in high risk women with increased mammographic breast density. Breast Cancer Res Treat 119(2):305-314