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Volumn 26, Issue 8, 2012, Pages 1752-1760

Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells

Author keywords

autophagy; chronic myeloid leukemia; imatinib; microRNA; stem cell

Indexed keywords

ANTAGOMIR; AUTOPHAGY PROTEIN 5; BECLIN 1; IMATINIB; MICRORNA; MICRORNA 30A; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

EID: 84864884448     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2012.65     Document Type: Article
Times cited : (172)

References (38)
  • 2
    • 66449122303 scopus 로고    scopus 로고
    • Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
    • Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, Ronchetti M et al. Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest 2009; 119: 1109-1123.
    • (2009) J Clin Invest , vol.119 , pp. 1109-1123
    • Bellodi, C.1    Lidonnici, M.R.2    Hamilton, A.3    Helgason, G.V.4    Soliera, A.R.5    Ronchetti, M.6
  • 3
    • 79952690221 scopus 로고    scopus 로고
    • Imatinib induces autophagy through BECLIN-1 and ATG5 genes in chronic myeloid leukemia cells
    • Can G, Ekiz HA, Baran Y. Imatinib induces autophagy through BECLIN-1 and ATG5 genes in chronic myeloid leukemia cells. Hematology 2011; 16: 95-99.
    • (2011) Hematology , vol.16 , pp. 95-99
    • Can, G.1    Ekiz, H.A.2    Baran, Y.3
  • 4
    • 80052164677 scopus 로고    scopus 로고
    • Kill one bird with two stones: Potential efficacy of BCR-ABL and autophagy inhibition in CML
    • Helgason GV, Karvela M, Holyoake TL. Kill one bird with two stones: potential efficacy of BCR-ABL and autophagy inhibition in CML. Blood 2011; 118: 2035-2043.
    • (2011) Blood , vol.118 , pp. 2035-2043
    • Helgason, G.V.1    Karvela, M.2    Holyoake, T.L.3
  • 5
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40: 280-293.
    • (2010) Mol Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 7
    • 80053634368 scopus 로고    scopus 로고
    • The dynamic nature of autophagy in cancer
    • Kimmelman AC. The dynamic nature of autophagy in cancer. Genes Dev 2011; 25: 1999-2010.
    • (2011) Genes Dev , vol.25 , pp. 1999-2010
    • Kimmelman, A.C.1
  • 8
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 9
    • 67650912359 scopus 로고    scopus 로고
    • The role of microRNA in human leukemia: A review
    • Yendamuri S, Calin GA. The role of microRNA in human leukemia: a review. Leukemia 2009; 23: 1257-1263.
    • (2009) Leukemia , vol.23 , pp. 1257-1263
    • Yendamuri, S.1    Calin, G.A.2
  • 10
    • 70350090620 scopus 로고    scopus 로고
    • MicroRNA expression profiling in imatinib-resistant chronic myeloid leukemia patients without clinically significant ABL1-mutations
    • San Jose-Eneriz E, Roman-Gomez J, Jimenez-Velasco A, Garate L, Martin V, Cordeu L et al. MicroRNA expression profiling in imatinib-resistant chronic myeloid leukemia patients without clinically significant ABL1-mutations. Mol Cancer 2009; 8: 69.
    • (2009) Mol Cancer , vol.8 , pp. 69
    • San Jose-Eneriz, E.1    Roman-Gomez, J.2    Jimenez-Velasco, A.3    Garate, L.4    Martin, V.5    Cordeu, L.6
  • 12
    • 84863011747 scopus 로고    scopus 로고
    • MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing Beclin 1-mediated autophagy
    • Zou Z, Wu L, Ding H, Wang Y, Zhang Y, Chen X et al. MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing Beclin 1-mediated autophagy. J Biol Chem 2012; 287: 4148-4156.
    • (2012) J Biol Chem , vol.287 , pp. 4148-4156
    • Zou, Z.1    Wu, L.2    Ding, H.3    Wang, Y.4    Zhang, Y.5    Chen, X.6
  • 13
    • 69449097865 scopus 로고    scopus 로고
    • Regulation of autophagy by a Beclin 1-targeted microRNA, miR-30a, in cancer cells
    • Zhu H, Wu H, Liu X, Li B, Chen Y, Ren X et al. Regulation of autophagy by a Beclin 1-targeted microRNA, miR-30a, in cancer cells. Autophagy 2009; 5: 816-823.
    • (2009) Autophagy , vol.5 , pp. 816-823
    • Zhu, H.1    Wu, H.2    Liu, X.3    Li, B.4    Chen, Y.5    Ren, X.6
  • 14
    • 83655190818 scopus 로고    scopus 로고
    • HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cells
    • Zhao M, Yang M, Yang L, Yu Y, Xie M, Zhu S et al. HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cells. BMB Rep 2011; 44: 601-606.
    • (2011) BMB Rep , vol.44 , pp. 601-606
    • Zhao, M.1    Yang, M.2    Yang, L.3    Yu, Y.4    Xie, M.5    Zhu, S.6
  • 15
    • 77958004008 scopus 로고    scopus 로고
    • Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein
    • Jaras M, Johnels P, Hansen N, Agerstam H, Tsapogas P, Rissler M et al. Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein. Proc Natl Acad Sci USA 2010; 107: 16280-16285.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 16280-16285
    • Jaras, M.1    Johnels, P.2    Hansen, N.3    Agerstam, H.4    Tsapogas, P.5    Rissler, M.6
  • 16
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 2010; 140: 313-326.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 18
    • 82155178703 scopus 로고    scopus 로고
    • ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia
    • Rousseau J, Gagne V, Labuda M, Beaubois C, Sinnett D, Laverdiere C et al. ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia. Blood 2011; 118: 5883-5890.
    • (2011) Blood , vol.118 , pp. 5883-5890
    • Rousseau, J.1    Gagne, V.2    Labuda, M.3    Beaubois, C.4    Sinnett, D.5    Laverdiere, C.6
  • 19
    • 0038454621 scopus 로고    scopus 로고
    • Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment
    • Bhatia R, Holtz M, Niu N, Gray R, Snyder DS, Sawyers CL et al. Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment. Blood 2003; 101: 4701-4707.
    • (2003) Blood , vol.101 , pp. 4701-4707
    • Bhatia, R.1    Holtz, M.2    Niu, N.3    Gray, R.4    Snyder, D.S.5    Sawyers, C.L.6
  • 20
    • 47049127238 scopus 로고    scopus 로고
    • Emerging stem cell concepts for imatinib-resistant chronic myeloid leukaemia: Implications for the biology, management, and therapy of the disease
    • Valent P. Emerging stem cell concepts for imatinib-resistant chronic myeloid leukaemia: implications for the biology, management, and therapy of the disease. Br J Haematol 2008; 142: 361-378.
    • (2008) Br J Haematol , vol.142 , pp. 361-378
    • Valent, P.1
  • 22
    • 68749103258 scopus 로고    scopus 로고
    • Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells
    • Gamas P, Marchetti S, Puissant A, Grosso S, Jacquel A, Colosetti P et al. Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells. Leukemia 2009; 23: 1500-1506.
    • (2009) Leukemia , vol.23 , pp. 1500-1506
    • Gamas, P.1    Marchetti, S.2    Puissant, A.3    Grosso, S.4    Jacquel, A.5    Colosetti, P.6
  • 23
    • 72949097628 scopus 로고    scopus 로고
    • Cytoprotective effect of imatinib mesylate in non-BCR-ABL-expressing cells along with autophagosome formation
    • Ohtomo T, Miyazawa K, Naito M, Moriya S, Kuroda M, Itoh M et al. Cytoprotective effect of imatinib mesylate in non-BCR-ABL-expressing cells along with autophagosome formation. Biochem Biophys Res Commun 2010; 391: 310-315.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 310-315
    • Ohtomo, T.1    Miyazawa, K.2    Naito, M.3    Moriya, S.4    Kuroda, M.5    Itoh, M.6
  • 24
    • 58849148000 scopus 로고    scopus 로고
    • MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes
    • Inomata M, Tagawa H, Guo YM, Kameoka Y, Takahashi N, Sawada K. MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. Blood 2009; 113: 396-402.
    • (2009) Blood , vol.113 , pp. 396-402
    • Inomata, M.1    Tagawa, H.2    Guo, Y.M.3    Kameoka, Y.4    Takahashi, N.5    Sawada, K.6
  • 25
    • 77954954098 scopus 로고    scopus 로고
    • MiR-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells
    • Yu F, Deng H, Yao H, Liu Q, Su F, Song E. miR-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells. Oncogene 2010; 29: 4194-4204.
    • (2010) Oncogene , vol.29 , pp. 4194-4204
    • Yu, F.1    Deng, H.2    Yao, H.3    Liu, Q.4    Su, F.5    Song, E.6
  • 26
    • 76749157966 scopus 로고    scopus 로고
    • MiR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway
    • Li J, Donath S, Li Y, Qin D, Prabhakar BS, Li P. miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway. PLoS Genet 2010; 6: e1000795.
    • (2010) PLoS Genet , vol.6
    • Li, J.1    Donath, S.2    Li, Y.3    Qin, D.4    Prabhakar, B.S.5    Li, P.6
  • 28
    • 34047207337 scopus 로고    scopus 로고
    • TP53 mutations in human cancers: Functional selection and impact on cancer prognosis and outcomes
    • Petitjean A, Achatz MI, Borresen-Dale AL, Hainaut P, Olivier M. TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Oncogene 2007; 26: 2157-2165.
    • (2007) Oncogene , vol.26 , pp. 2157-2165
    • Petitjean, A.1    Achatz, M.I.2    Borresen-Dale, A.L.3    Hainaut, P.4    Olivier, M.5
  • 29
    • 0036798565 scopus 로고    scopus 로고
    • Lack of p53 expression in human myeloid leukemias is not due to mutations in transcriptional regulatory regions of the gene
    • Durland-Busbice S, Reisman D. Lack of p53 expression in human myeloid leukemias is not due to mutations in transcriptional regulatory regions of the gene. Leukemia 2002; 16: 2165-2167.
    • (2002) Leukemia , vol.16 , pp. 2165-2167
    • Durland-Busbice, S.1    Reisman, D.2
  • 31
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • Kang R, Zeh HJ, Lotze MT, Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 2011; 18: 571-580.
    • (2011) Cell Death Differ , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 33
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993; 74: 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 34
    • 0032576692 scopus 로고    scopus 로고
    • Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c
    • Rosse T, Olivier R, Monney L, Rager M, Conus S, Fellay I et al. Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c. Nature 1998; 391: 496-499.
    • (1998) Nature , vol.391 , pp. 496-499
    • Rosse, T.1    Olivier, R.2    Monney, L.3    Rager, M.4    Conus, S.5    Fellay, I.6
  • 37
    • 0032571294 scopus 로고    scopus 로고
    • The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition
    • Pastorino JG, Chen ST, Tafani M, Snyder JW, Farber JL. The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition. J Biol Chem 1998; 273: 7770-7775.
    • (1998) J Biol Chem , vol.273 , pp. 7770-7775
    • Pastorino, J.G.1    Chen, S.T.2    Tafani, M.3    Snyder, J.W.4    Farber, J.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.