Chronic IL9 and IL-13 Exposure Leads to an Altered Differentiation of Ciliated Cells in a Well-Differentiated Paediatric Bronchial Epithelial Cell Model

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Parker, Jeremy C ^a   Thavagnanam, Surendran ^d   Skibinski, Grzegorz ^a   Lyons, Jeremy ^c   Bell, Jennifer ^a   Heaney, Liam G ^a   Shields, Michael D ^a,b  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b ROYAL BELFAST HOSPITAL FOR SICK CHILDREN   (United Kingdom)

^c ROYAL VICTORIA HOSPITAL   (United Kingdom)

^d UNIVERSITY MALAYA MEDICAL CENTRE   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; CYTOKINE; INTERLEUKIN 13; INTERLEUKIN 9; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MATRILYSIN; MESSENGER RNA; MUCIN; MUCIN 5AC;

ARTICLE; ASTHMA; BRONCHUS MUCOSA; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CHILD; CILIATED EPITHELIUM; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTRIC RESISTANCE; EPITHELIUM CELL; GOBLET CELL; HUMAN; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; INFANT; MUCOCILIARY CLEARANCE; PEDIATRICS; PRESCHOOL CHILD; PROTEIN LOCALIZATION; PROTEIN SECRETION; SCHOOL CHILD; TH2 CELL; TIGHT JUNCTION;

ASTHMA; BRONCHI; CELL COUNT; CELL DIFFERENTIATION; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CILIA; DRUG SYNERGISM; ELECTRIC IMPEDANCE; EPITHELIAL CELLS; GENE EXPRESSION; GOBLET CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; INTERLEUKIN-13; INTERLEUKIN-9; MATRIX METALLOPROTEINASE 7; MICROSCOPY, CONFOCAL; MUCIN 5AC; PROTO-ONCOGENE PROTEINS C-ETS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84877336618     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061023     Document Type: Article

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