Evaluation of safety and efficacy of brain targeted chitosan nanoparticles of minocycline

International Journal of Biological Macromolecules

Volumn 59, Issue , 2013, Pages 20-28

  Nagpal, Kalpana ^a   Singh, Shailendra Kumar ^a   Mishra, Dinanath ^a  

^a GURU JAMBHESHWAR UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

Chitosan nanoparticles; Histopathology; Maximum tolerated dose; Minocycline hydrochloride

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHITOSAN; CHOLESTEROL; FLUOXETINE; MINOCYCLINE; NANOPARTICLE; PLASMA PROTEIN; POLYSORBATE 80; SODIUM CHLORIDE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; AUTOPSY; BIOCHEMISTRY; BODY WEIGHT; CARDIOTOXICITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG SAFETY; DRUG TARGETING; ENCAPSULATION; ERYTHROCYTE COUNT; EXPERIMENTAL TEST; FORCED SWIMMING TEST; HISTOPATHOLOGY; IMMOBILIZATION; LEUKOCYTE COUNT; LIVER TOXICITY; LOCOMOTION; MALE; MAXIMUM TOLERATED DOSE; MOUSE; NEPHROTOXICITY; NEUROTOXICITY; NONHUMAN; ORGAN WEIGHT; SPLEEN DISEASE; TAIL SUSPENSION TEST; THROMBOCYTE COUNT; TREATMENT DURATION; WEIGHT REDUCTION;

EID: 84877328383     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2013.04.011     Document Type: Article

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