ICaL inhibition prevents arrhythmogenic Ca2+ waves caused by abnormal Ca2+ sensitivity of RyR or SR Ca2+ accumulation

Cardiovascular Research

Volumn 98, Issue 2, 2013, Pages 315-325

  Stokke, Mathis K ^a,b,c   Tovsrud, Nils ^a,b   Louch, William E ^a,b   Øyehaug, Leiv ^a,b   Hougen, Karina ^a,b   Sejersted, Ole M ^a,b   Swift, Fredrik ^a,b   Sjaastad, Ivar ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c LOVISENBERG DIAKONALE HOSPITAL   (Norway)

Author keywords

Ca2+ homeostasis; Ca2+ sparks; Ca2+ waves; L type Ca2+ current; sarcoplasmic reticulum function

Indexed keywords

ANKYRIN; ANKYRIN B; CAFFEINE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL L TYPE; ISOPRENALINE; NICARDIPINE; PHOSPHOLAMBAN; RYANODINE RECEPTOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ARRHYTHMOGENESIS; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ELECTROSTIMULATION; ENZYME ACTIVITY; HEART LEFT VENTRICLE; HEART MUSCLE CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SARCOPLASMIC RETICULUM;

ANIMALS; ARRHYTHMIAS, CARDIAC; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, ADRENERGIC, BETA; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOLEMMA; SARCOPLASMIC RETICULUM; VERAPAMIL;

EID: 84877286907     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt037     Document Type: Article

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