Synergism of Green Tea Polyphenols and Phenanthrene Promotes the Death of Human Lung Adenocarcinoma Cell Line SPC-A-1

Polycyclic Aromatic Compounds

Volumn 33, Issue 3, 2013, Pages 254-264

  Mei, Xin ^a,b   Xu, Yuan Jun ^a   Pan, Hai Bo ^a   Tu, You Ying ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b SOUTH CHINA INSTITUTE OF BOTANY   (China)

Author keywords

cancer cell; green tea polyphenols; phenanthrene; synergism

Indexed keywords

ANTHRACENE; BIOLOGICAL ORGANS; CELL CULTURE; DISEASES;

ANTICARCINOGENS; CANCER CELLS; CANCER RISK; CELL CYCLE; CELL LINES; GREEN TEA POLYPHENOLS; HUMAN LUNG ADENOCARCINOMA CELLS; PHENANTHRENE; SYNERGISM; TEA-LEAVES;

CELL DEATH;

EID: 84877258243     PISSN: 10406638     EISSN: 15635333     Source Type: Journal    
DOI: 10.1080/10406638.2013.767846     Document Type: Article

References (24)

1. Lin, D. H., Tu, Y. Y. and Zhu, L. Z. 2005. Concentrations and Health Risk of Polycyclic Aromatic Hydrocarbons in Tea. Food. Chem. Toxicol., 43: 41-8.
2. Lin, D., Zhu, L., He, W. and Tu, Y. 2006. Tea Plant Uptake and Translocation of Polycyclic Aromatic Hydrocarbons from Water and around Air. J. Agric. Food. Chem., 54: 3658-62.
3. Dusek, B., Hajskova, J. and Kocourek, V. 2002. Determination of Nitrated Polycyclic Aromatic Hydrocarbons and Their Precursors in Biotic Matrices. J. Chromatogr. A., 982: 127-43.
4. Monarca, S., Feretti, D., Zanardini, A., Moretti, M., Villarini, M., Spiegelhalder, B., Zerbini, I., Gelatti, U. and Lebbolo, E. 2001. Monitoring Airborne Genotoxicants in the Rubber Industry Using Genotoxicity Tests and Chemical Analyses. Mutat. Res.-Gen. Tox. En., 490: 159-69.
5. Platt, K. L., Aderhold, S., Kulpe, K. and Fickler, M. 2008. Unexpected DNA Damage Caused by Polycyclic Aromatic Hydrocarbons under Standard Laboratory Conditions. Mutat. Res., 650: 96-103.
6. Kovacs, A., Vasas, A. and Hohmann, J. 2008. Natural Phenanthrenes and Their Biological Activity. Phytochemistry, 69: 1084-10.
7. Mei, X., Lin, D. H., Xu, Y., Wu, Y. Y. and Tu, Y. Y. 2009. Effects of Phenanthrene on Chemical Composition and Enzyme Activity in Fresh Tea Leaves. Food Chem., 115: 569-73.
8. Kuroda, Y. and Hara, Y. 1999. Antimutagenic and Anticarcinogenic Activity of Tea Polyphenols. Mutat. Res.-Rev. Mutat., 436: 69-97.
9. Li, W., Wu, J. X. and Tu, Y. Y. 2010. Synergistic Effects of Tea Polyphenols and Ascorbic Acid on Human Lung Adenocarcinoma Spc-a-1 Cells. J. Zhejiang Univ. Sci. B., 11: 458-64.
10. Li, B., Jin, Y., Xu, Y., Wu, Y., Xu, J. and Tu, Y. 2011. Safety Evaluation of Tea (Camellia Sinensis (L.) O. Kuntze) Flower Extract: Assessment of Mutagenicity, and Acute and Subchronic Toxicity in Rats. J. Ethnopharmacol., 133: 583-90.
11. Williams, S. N., Shih, H., Guenette, D. K., Brackney, W., Denison, M. S., Pickwell, G. V. and Quattrochi, L. C. 2000. Comparative Studies on the Effects of Green Tea Extracts and Individual Tea Catechins on Human Cyp1a Gene Expression. Chem.-Biol. Interact., 128: 211-29.
12. Mei, X., Wu, Y. Y., Mao, X. and Tu, Y. Y. 2011. Antagonism of Phenanthrene Cytotoxicity for Human Embryo Lung Fibroblast Cell Line Hfl-I by Green Tea Polyphenols. Environ. Pollut., 159: 164-8.
13. Ahmad, N., Gupta, S. and Mukhtar, H. 2000. Green Tea Polyphenol Epigallocatechin-3-Gallate Differentially Modulates Nuclear Factor Kappab in Cancer Cells Versus Normal Cells. Arch. Biochem. Biophys., 376: 338-46.
14. Ahmad, N., Feyes, D. K., Nieminen, A. L., Agarwal, R. and Mukhtar, H. 1997. Green Tea Constituent Epigallocatechin-3-Gallate and Induction of Apoptosis and Cell Cycle Arrest in Human Carcinoma Cells. J. Natl. Cancer Instit., 89: 1881-6.
15. Dvorak, Z., Henklova, P., Vrzal, R. and Ulrichova, J. 2008. Role of Mitogen-Activated Protein Kinases in Aryl Hydrocarbon Receptor Signaling. Chem.-Biol. Interact, 172: 93-104.
16. Chou, T. C. and Talalay, P. 1984. Quantitative-Analysis of Dose-Effect Relationships-the Combined Effects of Multiple-Drugs or Enzyme-Inhibitors. Adv. Enzyme Regul., 22: 27-55.
17. Banerjee, S., Manna, S., Saha, P., Panda, C. K. and Das, S. 2005. Black Tea Polyphenols Suppress Cell Proliferation and Induce Apoptosis During Benzo(a)Pyrene-Induced Lung Carcinogenesis. Eur. J. Cancer Prev., 14: 215-21.
18. Belguise, K., Guo, S., Yang, S., Rogers, A. E., Seldin, D. C., Sherr, D. H. and Sonenshein, G. E. 2007. Green Tea Polyphenols Reverse Cooperation between C-Rel and Ck2 That Induces the Aryl Hydrocarbon Receptor, Slug, and an Invasive Phenotype. Cancer Res., 67: 11742-50.
19. Cao, P., Vadhanam, M. V., Spencer, W. A., Cai, J. and Gupta, R. C. 2011. Sustained Systemic Delivery of Green Tea Polyphenols by Polymeric Implants Significantly Diminishes Benzo[a]Pyrene-Induced DNA Adducts. Chem. Res. Toxicol., 24: 877-86.
20. Shankar, S., Suthakar, G. and Srivastava, R. K. 2007. Epigallocatechin-3-Gallate Inhibits Cell Cycle and Induces Apoptosis in Pancreatic Cancer. Front Biosci., 12: 5039-51.
21. Park, H. K., Han, D. W., Park, Y. H. and Park, J. C. 2005. Differential Biological Responses of Green Tea Polyphenol in Normal Cells Vs. Cancer Cells. Curr. Appl. Phys., 5: 449-52.
22. Hadi, S. M., Ullah, M. F., Azmi, A. S., Ahmad, A., Shamim, U., Zubair, H. and Khan, H. Y. 2010. Resveratrol Mobilizes Endogenous Copper in Human Peripheral Lymphocytes Leading to Oxidative DNA Breakage: A Putative Mechanism for Chemoprevention of Cancer. Pharmaceut. Res., 27: 979-88.
23. Zhong, Q., Amin, S., Lazarus, P. and Spratt, T. E. 2010. Differential Repair of Polycyclic Aromatic Hydrocarbon DNA Adducts from an Actively Transcribed Gene. DNA Repair (Amst.), 9: 1011-6.
24. Zhang, G. N., Zhong, L. Y., Bligh, S. W., Guo, Y. L., Zhang, C. F., Zhang, M., Wang, Z. T. and Xu, L. S. 2005. Bi-Bicyclic and Bi-Tricyclic Compounds from Dendrobium Thyrsiflorum. Phytochemistry, 66: 1113-20.