The PI3K/Akt pathway mediates the protection of SO 2 preconditioning against myocardial ischemia/reperfusion injury in rats

Acta Pharmacologica Sinica

Volumn 34, Issue 4, 2013, Pages 501-506

  Zhao, Man Man ^a   Yang, Jin Yan ^a   Wang, Xin Bao ^a   Tang, Chao Shu ^b,c   Du, Jun Bao ^a,b   Jin, Hong Fang ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Caspase 3; Caspase 9; Creatine kinase; Heart infarct; Ischemia reperfusion; LDH; LY294002; PI3K Akt pathway; Preconditioning; Sulfur dioxide

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; CASPASE 9; CREATINE KINASE; LACTATE DEHYDROGENASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P85; SULFUR DIOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART INFARCTION; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

ANIMALS; CASPASE 3; CASPASE 9; CHROMONES; CORONARY VESSELS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MORPHOLINES; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RANDOM ALLOCATION; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SULFUR DIOXIDE;

EID: 84877254430     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.204     Document Type: Article

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