-
1
-
-
33846403492
-
Pathological and physiological functions of presenilins
-
Vetrivel KS, Zhang YW, Xu H, Thinakaran G, (2006) Pathological and physiological functions of presenilins. Mol Neurodegener 1: 4.
-
(2006)
Mol Neurodegener
, vol.1
, pp. 4
-
-
Vetrivel, K.S.1
Zhang, Y.W.2
Xu, H.3
Thinakaran, G.4
-
2
-
-
65249188697
-
Intramembrane proteolysis
-
Wolfe MS, (2009) Intramembrane proteolysis. Chem Rev 109: 1599-1612.
-
(2009)
Chem Rev
, vol.109
, pp. 1599-1612
-
-
Wolfe, M.S.1
-
3
-
-
0033535508
-
Presenilin is required for activity and nuclear access of Notch in Drosophila
-
Struhl G, Greenwald I, (1999) Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature 398: 522-525.
-
(1999)
Nature
, vol.398
, pp. 522-525
-
-
Struhl, G.1
Greenwald, I.2
-
4
-
-
79953167471
-
Presenilins promote the cellular uptake of copper and zinc and maintain copper chaperone of SOD1-dependent copper/zinc superoxide dismutase activity
-
Greenough MA, Volitakis I, Li QX, Laughton K, Evin G, et al. (2011) Presenilins promote the cellular uptake of copper and zinc and maintain copper chaperone of SOD1-dependent copper/zinc superoxide dismutase activity. J Biol Chem 286: 9776-9786.
-
(2011)
J Biol Chem
, vol.286
, pp. 9776-9786
-
-
Greenough, M.A.1
Volitakis, I.2
Li, Q.X.3
Laughton, K.4
Evin, G.5
-
5
-
-
84875697145
-
Metal dyshomeostasis and oxidative stress in Alzheimer's disease
-
Greenough MA, Camakaris J, Bush AI (2012) Metal dyshomeostasis and oxidative stress in Alzheimer's disease. Neurochem Int http://dx.doi.org/10.1016/j.neuint.2012.08.014.
-
(2012)
Neurochem Int
-
-
Greenough, M.A.1
Camakaris, J.2
Bush, A.I.3
-
6
-
-
18544371009
-
Metals, toxicity and oxidative stress
-
Valko M, Morris H, Cronin MT, (2005) Metals, toxicity and oxidative stress. Curr Med Chem 12: 1161-1208.
-
(2005)
Curr Med Chem
, vol.12
, pp. 1161-1208
-
-
Valko, M.1
Morris, H.2
Cronin, M.T.3
-
7
-
-
74949100486
-
New developments in the regulation of intestinal copper absorption
-
van den Berghe PV, Klomp LW, (2009) New developments in the regulation of intestinal copper absorption. Nutr Rev 67: 658-672.
-
(2009)
Nutr Rev
, vol.67
, pp. 658-672
-
-
van den Berghe, P.V.1
Klomp, L.W.2
-
9
-
-
33746889803
-
Copper homeostasis in eukaryotes: teetering on a tightrope
-
Balamurugan K, Schaffner W, (2006) Copper homeostasis in eukaryotes: teetering on a tightrope. Biochim Biophys Acta 1763: 737-746.
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 737-746
-
-
Balamurugan, K.1
Schaffner, W.2
-
10
-
-
77953364380
-
Tissue-specific interplay between copper uptake and efflux in Drosophila
-
Binks T, Lye JC, Camakaris J, Burke R, (2010) Tissue-specific interplay between copper uptake and efflux in Drosophila. J Biol Inorg Chem 15: 621-628.
-
(2010)
J Biol Inorg Chem
, vol.15
, pp. 621-628
-
-
Binks, T.1
Lye, J.C.2
Camakaris, J.3
Burke, R.4
-
11
-
-
68849129637
-
Dietary zinc absorption is mediated by ZnT1 in Drosophila melanogaster
-
Wang X, Wu Y, Zhou B, (2009) Dietary zinc absorption is mediated by ZnT1 in Drosophila melanogaster. Faseb J 23: 2650-2661.
-
(2009)
Faseb J
, vol.23
, pp. 2650-2661
-
-
Wang, X.1
Wu, Y.2
Zhou, B.3
-
12
-
-
30044445876
-
Essential roles in development and pigmentation for the Drosophila copper transporter DmATP7
-
Norgate M, Lee E, Southon A, Farlow A, Batterham P, et al. (2006) Essential roles in development and pigmentation for the Drosophila copper transporter DmATP7. Mol Biol Cell 17: 475-484.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 475-484
-
-
Norgate, M.1
Lee, E.2
Southon, A.3
Farlow, A.4
Batterham, P.5
-
13
-
-
33646811833
-
Brush border spectrin is required for early endosome recycling in Drosophila
-
Phillips MD, Thomas GH, (2006) Brush border spectrin is required for early endosome recycling in Drosophila. J Cell Sci 119: 1361-1370.
-
(2006)
J Cell Sci
, vol.119
, pp. 1361-1370
-
-
Phillips, M.D.1
Thomas, G.H.2
-
14
-
-
34247854158
-
Cis-regulatory elements in the Accord retrotransposon result in tissue-specific expression of the Drosophila melanogaster insecticide resistance gene Cyp6g1
-
Chung H, Bogwitz MR, McCart C, Andrianopoulos A, Ffrench-Constant RH, et al. (2007) Cis-regulatory elements in the Accord retrotransposon result in tissue-specific expression of the Drosophila melanogaster insecticide resistance gene Cyp6g1. Genetics 175: 1071-1077.
-
(2007)
Genetics
, vol.175
, pp. 1071-1077
-
-
Chung, H.1
Bogwitz, M.R.2
McCart, C.3
Andrianopoulos, A.4
Ffrench-Constant, R.H.5
-
15
-
-
17444417126
-
Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes
-
Selvaraj A, Balamurugan K, Yepiskoposyan H, Zhou H, Egli D, et al. (2005) Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes. Genes Dev 19: 891-896.
-
(2005)
Genes Dev
, vol.19
, pp. 891-896
-
-
Selvaraj, A.1
Balamurugan, K.2
Yepiskoposyan, H.3
Zhou, H.4
Egli, D.5
-
16
-
-
7444240167
-
Copper homoeostasis in Drosophila melanogaster S2 cells
-
Southon A, Burke R, Norgate M, Batterham P, Camakaris J, (2004) Copper homoeostasis in Drosophila melanogaster S2 cells. Biochem J 383: 303-309.
-
(2004)
Biochem J
, vol.383
, pp. 303-309
-
-
Southon, A.1
Burke, R.2
Norgate, M.3
Batterham, P.4
Camakaris, J.5
-
17
-
-
34248666410
-
Copper homeostasis gene discovery in Drosophila melanogaster
-
Norgate M, Southon A, Zou S, Zhan M, Sun Y, et al. (2007) Copper homeostasis gene discovery in Drosophila melanogaster. Biometals 20: 683-697.
-
(2007)
Biometals
, vol.20
, pp. 683-697
-
-
Norgate, M.1
Southon, A.2
Zou, S.3
Zhan, M.4
Sun, Y.5
-
18
-
-
33646145729
-
Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology
-
Maynard CJ, Cappai R, Volitakis I, Cherny RA, Masters CL, et al. (2006) Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology. J Inorg Biochem 100: 952-962.
-
(2006)
J Inorg Biochem
, vol.100
, pp. 952-962
-
-
Maynard, C.J.1
Cappai, R.2
Volitakis, I.3
Cherny, R.A.4
Masters, C.L.5
-
19
-
-
0033950664
-
A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1)
-
Peskin AV, Winterbourn CC, (2000) A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1). Clin Chim Acta 293: 157-166.
-
(2000)
Clin Chim Acta
, vol.293
, pp. 157-166
-
-
Peskin, A.V.1
Winterbourn, C.C.2
-
20
-
-
0000138540
-
Effects of PS1 deficiency on membrane protein trafficking in neurons
-
Naruse S, Thinakaran G, Luo JJ, Kusiak JW, Tomita T, et al. (1998) Effects of PS1 deficiency on membrane protein trafficking in neurons. Neuron 21: 1213-1221.
-
(1998)
Neuron
, vol.21
, pp. 1213-1221
-
-
Naruse, S.1
Thinakaran, G.2
Luo, J.J.3
Kusiak, J.W.4
Tomita, T.5
-
21
-
-
70350304571
-
Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities
-
Yu JT, Chang RC, Tan L, (2009) Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities. Prog Neurobiol 89: 240-255.
-
(2009)
Prog Neurobiol
, vol.89
, pp. 240-255
-
-
Yu, J.T.1
Chang, R.C.2
Tan, L.3
-
22
-
-
84862883617
-
A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2
-
Zhang X, Garbett K, Veeraraghavalu K, Wilburn B, Gilmore R, et al. (2012) A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2. J Neurosci 32: 8633-8648.
-
(2012)
J Neurosci
, vol.32
, pp. 8633-8648
-
-
Zhang, X.1
Garbett, K.2
Veeraraghavalu, K.3
Wilburn, B.4
Gilmore, R.5
-
23
-
-
33846603681
-
Fly foie gras: modeling fatty liver in Drosophila
-
Arquier N, Leopold P, (2007) Fly foie gras: modeling fatty liver in Drosophila. Cell Metab 5: 83-85.
-
(2007)
Cell Metab
, vol.5
, pp. 83-85
-
-
Arquier, N.1
Leopold, P.2
-
24
-
-
33644871413
-
The Malpighian tubule: rapid insights from post-genomic biology
-
Dow JA, Davies SA, (2006) The Malpighian tubule: rapid insights from post-genomic biology. J Insect Physiol 52: 365-378.
-
(2006)
J Insect Physiol
, vol.52
, pp. 365-378
-
-
Dow, J.A.1
Davies, S.A.2
-
25
-
-
79956310601
-
Changes in the expression of the Alzheimer's disease-associated presenilin gene in drosophila heart leads to cardiac dysfunction
-
Li A, Zhou C, Moore J, Zhang P, Tsai TH, et al. (2011) Changes in the expression of the Alzheimer's disease-associated presenilin gene in drosophila heart leads to cardiac dysfunction. Curr Alzheimer Res 8: 313-322.
-
(2011)
Curr Alzheimer Res
, vol.8
, pp. 313-322
-
-
Li, A.1
Zhou, C.2
Moore, J.3
Zhang, P.4
Tsai, T.H.5
-
26
-
-
33845217332
-
Mutations of presenilin genes in dilated cardiomyopathy and heart failure
-
Li D, Parks SB, Kushner JD, Nauman D, Burgess D, et al. (2006) Mutations of presenilin genes in dilated cardiomyopathy and heart failure. Am J Hum Genet 79: 1030-1039.
-
(2006)
Am J Hum Genet
, vol.79
, pp. 1030-1039
-
-
Li, D.1
Parks, S.B.2
Kushner, J.D.3
Nauman, D.4
Burgess, D.5
-
27
-
-
33845655221
-
Presenilin/gamma-secretase activity regulates protein clearance from the endocytic recycling compartment
-
Zhang M, Haapasalo A, Kim DY, Ingano LA, Pettingell WH, et al. (2006) Presenilin/gamma-secretase activity regulates protein clearance from the endocytic recycling compartment. FASEB J 20: 1176-1178.
-
(2006)
FASEB J
, vol.20
, pp. 1176-1178
-
-
Zhang, M.1
Haapasalo, A.2
Kim, D.Y.3
Ingano, L.A.4
Pettingell, W.H.5
-
28
-
-
31044438340
-
Regulation of tyrosinase trafficking and processing by presenilins: partial loss of function by familial Alzheimer's disease mutation
-
Wang R, Tang P, Wang P, Boissy RE, Zheng H, (2006) Regulation of tyrosinase trafficking and processing by presenilins: partial loss of function by familial Alzheimer's disease mutation. Proc Natl Acad Sci U S A 103: 353-358.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 353-358
-
-
Wang, R.1
Tang, P.2
Wang, P.3
Boissy, R.E.4
Zheng, H.5
-
29
-
-
78650862568
-
Syntaxin 5 is required for copper homeostasis in Drosophila and mammals
-
Norgate M, Southon A, Greenough M, Cater M, Farlow A, et al. (2010) Syntaxin 5 is required for copper homeostasis in Drosophila and mammals. PLoS One 5: e14303.
-
(2010)
PLoS One
, vol.5
-
-
Norgate, M.1
Southon, A.2
Greenough, M.3
Cater, M.4
Farlow, A.5
-
30
-
-
58149094426
-
Instability of superoxide dismutase 1 of Drosophila in mutants deficient for its cognate copper chaperone
-
Kirby K, Jensen LT, Binnington J, Hilliker AJ, Ulloa J, et al. (2008) Instability of superoxide dismutase 1 of Drosophila in mutants deficient for its cognate copper chaperone. J Biol Chem 283: 35393-35401.
-
(2008)
J Biol Chem
, vol.283
, pp. 35393-35401
-
-
Kirby, K.1
Jensen, L.T.2
Binnington, J.3
Hilliker, A.J.4
Ulloa, J.5
-
31
-
-
0034646410
-
Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase
-
Wong PC, Waggoner D, Subramaniam JR, Tessarollo L, Bartnikas TB, et al. (2000) Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase. Proc Natl Acad Sci U S A 97: 2886-2891.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2886-2891
-
-
Wong, P.C.1
Waggoner, D.2
Subramaniam, J.R.3
Tessarollo, L.4
Bartnikas, T.B.5
-
32
-
-
0034882160
-
Low-activity allele of copper-zinc superoxide dismutase (CuZnSOD) in Drosophila increases paraquat genotoxicity but does not affect near UV radiation damage
-
Vontas JG, Tsakas SC, Loukas M, Hemingway J, (2001) Low-activity allele of copper-zinc superoxide dismutase (CuZnSOD) in Drosophila increases paraquat genotoxicity but does not affect near UV radiation damage. Genome 44: 597-601.
-
(2001)
Genome
, vol.44
, pp. 597-601
-
-
Vontas, J.G.1
Tsakas, S.C.2
Loukas, M.3
Hemingway, J.4
-
33
-
-
0032031780
-
Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease
-
Marcus DL, Thomas C, Rodriguez C, Simberkoff K, Tsai JS, et al. (1998) Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease. Exp Neurol 150: 40-44.
-
(1998)
Exp Neurol
, vol.150
, pp. 40-44
-
-
Marcus, D.L.1
Thomas, C.2
Rodriguez, C.3
Simberkoff, K.4
Tsai, J.S.5
-
34
-
-
84455161651
-
SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid beta protein oligomerization and memory loss in mouse model of Alzheimer disease
-
Murakami K, Murata N, Noda Y, Tahara S, Kaneko T, et al. (2011) SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid beta protein oligomerization and memory loss in mouse model of Alzheimer disease. J Biol Chem 286: 44557-44568.
-
(2011)
J Biol Chem
, vol.286
, pp. 44557-44568
-
-
Murakami, K.1
Murata, N.2
Noda, Y.3
Tahara, S.4
Kaneko, T.5
-
35
-
-
77952482502
-
Control of Alzheimer's amyloid beta toxicity by the high molecular weight immunophilin FKBP52 and copper homeostasis in Drosophila
-
Sanokawa-Akakura R, Cao W, Allan K, Patel K, Ganesh A, et al. (2010) Control of Alzheimer's amyloid beta toxicity by the high molecular weight immunophilin FKBP52 and copper homeostasis in Drosophila. PLoS One 5: e8626.
-
(2010)
PLoS One
, vol.5
-
-
Sanokawa-Akakura, R.1
Cao, W.2
Allan, K.3
Patel, K.4
Ganesh, A.5
-
36
-
-
80052779276
-
Toxicity of Alzheimer's disease-associated Abeta peptide is ameliorated in a Drosophila model by tight control of zinc and copper availability
-
Hua H, Munter L, Harmeier A, Georgiev O, Multhaup G, et al. (2011) Toxicity of Alzheimer's disease-associated Abeta peptide is ameliorated in a Drosophila model by tight control of zinc and copper availability. Biol Chem 392: 919-926.
-
(2011)
Biol Chem
, vol.392
, pp. 919-926
-
-
Hua, H.1
Munter, L.2
Harmeier, A.3
Georgiev, O.4
Multhaup, G.5
|