Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes

Genes and Development

Volumn 19, Issue 8, 2005, Pages 891-896

  Selvaraj, Anand ^a   Balamurugan, Kuppusamy ^a   Yepiskoposyan, Hasmik ^a   Zhou, Hao ^b   Egli, Dieter ^a   Georgiev, Oleg ^a   Thiele, Dennis J ^c   Schaffner, Walter ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Copper depletion; Copper load; CtrlB; Metal response elements; Metallothioneins; Transcription factor MTF 1

Indexed keywords

COPPER; METALLOTHIONEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MTF 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COPPER METABOLISM; CTR1B GENE; DETOXIFICATION; DNA RESPONSIVE ELEMENT; DNA SEQUENCE; DROSOPHILA; GENE; GENE ACTIVATION; GENE EXPRESSION; METAL RESPONSE ELEMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; TRANSCRIPTION INITIATION;

ANIMALS; BIOLOGICAL TRANSPORT; CATION TRANSPORT PROTEINS; CELLS, CULTURED; COMPUTATIONAL BIOLOGY; COPPER; DNA-BINDING PROTEINS; DROSOPHILA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE COMPONENTS; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; ION TRANSPORT; METALLOTHIONEIN; PROTEIN BINDING; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 17444417126     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1301805     Document Type: Article

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