CMV promoter is repressed by p53 and activated by JNK pathway

Plasmid

Volumn 69, Issue 3, 2013, Pages 223-230

  Rodova, Marianna ^a   Jayini, Renuka ^a   Singasani, Reddy ^a   Chipps, Elizabeth ^a   Islam, M Rafiq ^a  

^a NORTHWEST MISSOURI STATE UNIVERSITY   (United States)

Author keywords

CMV; JNK pathway; Mekk1; P53; RSV; SV; Viral promoters

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; PROTEIN FOS; PROTEIN P51; STRESS ACTIVATED PROTEIN KINASE; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR AP 1;

ARTICLE; BINDING SITE; CELL STRAIN HEK293; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; CYTOMEGALOVIRUS; EXPRESSION VECTOR; GENE REPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PROMOTER REGION; SIGNAL TRANSDUCTION; TATA BOX;

BASE SEQUENCE; BINDING SITES; CONSENSUS SEQUENCE; CYTOMEGALOVIRUS; ENZYME ACTIVATION; GENETIC VECTORS; HEK293 CELLS; HUMANS; MAP KINASE KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MOLECULAR SEQUENCE DATA; PROTEIN INTERACTION MAPPING; TATA BOX; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53;

RICE STRIPE VIRUS;

EID: 84877125846     PISSN: 0147619X     EISSN: 10959890     Source Type: Journal    
DOI: 10.1016/j.plasmid.2013.01.004     Document Type: Article

References (27)

1. Angel P., Imagawa M., Chiu R., Stein B., Imbra R.J., Rahmsdorf H.J., Jonat C., Herrlich P., Karin M. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 1987, 49:729-739.
2. Beckerman R., Prives C. Transcriptional regulation by p53. Cold Spring Harb. Perspect. Biol. 2010, 2:a000935.
3. Benbrook D.M., Jones N.C. Heterodimer formation between CREB and JUN proteins. Oncogene 1990, 5:295-302.
4. Crighton D., Woiwode A., Zhang C., Mandavia N., Morton J.P., Warnock L.J., Milner J., White R.J., Johnson D.L. P53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB. EMBO J. 2003, 22:2810-2820.
5. El-Deiry W.S., Kern S.E., Pietenpol J.A., Kinzler K.W., Vogelstein B. Definition of a consensus binding site for p53. Nat. Genet. 1992, 1:45-49.
6. Farmer G., Colgan J., Nakatani Y., Manley J.L., Prives C. Functional interaction between p53, the TATA-binding protein (TBP), and TBP-associated factors in vivo. Mol. Cell. Biol. 1996, 16:4295-4304.
7. Hagemann C., Blank J.L. The ups and downs of MEK kinase interactions. Cell. Signal. 2001, 13:863-875.
8. Johnson R.A., Ince T.A., Scotto K.W. Transcriptional repression by p53 through direct binding to a novel DNA element. J. Biol. Chem. 2001, 276:27716-27720.
9. Islam M.R., Jimenez T., Pelham C., Rodova M., Puri S., Magenhaimer B.S., Maser R.L., Widmann C., Calvet J.P. MAP/ERK kinase kinase 1 (MEKK1) mediates transcriptional repression by interacting with polycystic kidney disease-1 (PKD1) promoter-bound p53 tumor suppressor protein. J. Biol. Chem. 2010, 285:38818-38831.
10. Kanaya T., Kyo S., Hamada K., Takakura M., Kitagawa Y., Harada H., Inoue M. Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription. Clin. Cancer Res. 2000, 6:1239-1247.
11. Kubicka S., Kuhnel F., Zender L., Rudolph K.L., Plumpe J., Manns M., Trautwein C. P53 represses CAAT enhancer-binding protein (C/EBP)-dependent transcription of the albumin gene. A molecular mechanism involved in viral liver infection with implications for hepatocarcinogenesis. J. Biol. Chem. 1999, 274:32137-32144.
12. Levine A.J. P53, the cellular gatekeeper for growth and division. Cell 1997, 88:323-331.
13. Mack D.H., Vartikar J., Pipas J.M., Laimins L.A. Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53. Nature 1993, 363:281-283.
14. Maillet M., Lynch J.M., Sanna B., York A.J., Zheng Y., Molkentin J.D. Cdc42 is an antihypertrophic molecular switch in the mouse heart. J. Clin. Invest. 2009, 119:3079-3088.
15. Montminy M.R., Bilezikjian L.M. Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene. Nature 1987, 328:175-178.
16. Ragimov N., Krauskopf A., Navot N., Rotter V., Oren M., Aloni Y. Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif. Oncogene 1993, 8:1183-1193.
17. Shaulian E., Karin M. AP-1 in cell proliferation and survival. Oncogene 2001, 20:2390-2400.
18. Seto E., Usheva A., Zambetti G.P., Momand J., Horikoshi N., Weinmann R., Levine A.J., Shenk T. Wild-type p53 binds to the TATA-binding protein and represses transcription. Proc. Natl. Acad. Sci. USA 1992, 89:12028-12032.
19. Stinski M.F. Cytomegalovirus promoter for expression in mammalian cells. Gene Expression Systems: Using Nature for the Art of Expression 1999, 211-233. Academiv Press, San Diego, California. J.M. Fernandez, J.P. Hoeffler (Eds.).
20. Suubaramaiah K., Altorkil N., Chung W.J., Mestre J.R., Sampat A., Dannenberg A.J. Inhibition of cyclooxygenase-2 gene expression by p53. J. Biol. Chem. 1999, 274:10911-10915.
21. Sun Y., Zeng X.R., Wenger L., Firestein G.S., Cheung H.S. P53 down-regulates matrix metalloproteinase-1 by targeting the communications between AP-1 and the basal transcription complex. J. Cell. Biochem. 2004, 92:258-269.
22. Thut C.J., Chen J.L., Klemm R., Tjian R. P53 transcriptional activation mediated by coactivators TAFII40 and TAFII60. Science 1995, 267:100-104.
23. Truant R., Xiao H., Ingles C.J., Greenbladt J. Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein. J Biol. Chem. 1993, 268:2284-2287.
24. Venot C., Maratrat M., Dureuil C., Conseiller E., Bracco L., Debussche L. The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression. EMBO J. 1998, 17:4668-4679.
25. Werner H., Karnieli E., Rauscher F.J., LeRoith D. Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene. Proc. Natl. Acad. Sci. U S A. 1996, 93:8318-8323.
26. Wu Y., Mehew J.W., Heckman C.A., Arcinas M., Boxer L.M. Negative regulation of bcl-2 expression by p53 in hematopoietic cells. Oncogene 2001, 20:240-251.
27. Yun J., Chae H.D., Choy H.E., Chung J., Yoo H.S., Han M.H., Shin D.Y. P53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor. J. Biol. Chem. 1999, 274:29677-29682.