Cushing's syndrome after intralesional triamcinolone acetonide: A systematic review of the literature and multinational survey

Burns

Volumn 39, Issue 4, 2013, Pages 549-557

  Fredman, Rafi ^a   Tenenhaus, Mayer ^b  

^a TEL AVIV UNIVERSITY   (Israel)

^b UCSD MEDICAL CENTER   (United States)

Author keywords

Burn injury; Cushing's syndrome; Hypertrophic scar; Keloid; Triamcinolone acetonide

Indexed keywords

TRIAMCINOLONE ACETONIDE;

ACNE; CUSHING SYNDROME; CUSHINGOID SYNDROME; DEPIGMENTATION; DRUG SAFETY; FOLLOW UP; HEALTH SURVEY; HUMAN; HYPERTROPHIC SCAR; HYPOPIGMENTATION; KELOID; MENORRHAGIA; MENSTRUATION DISORDER; OUTCOME ASSESSMENT; PATIENT EDUCATION; PLASTIC SURGEON; RECOMMENDED DRUG DOSE; REVIEW; RISK FACTOR; SKIN ATROPHY; SKIN DISCOLORATION; SYSTEMATIC REVIEW; TELANGIECTASIA;

ADULT; AGE FACTORS; ANTI-INFLAMMATORY AGENTS; CHILD; CICATRIX; CUSHING SYNDROME; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOCORTICOIDS; HUMANS; INJECTIONS, INTRALESIONAL; PHYSICIAN'S PRACTICE PATTERNS; TRIAMCINOLONE ACETONIDE;

EID: 84877096163     PISSN: 03054179     EISSN: 18791409     Source Type: Journal    
DOI: 10.1016/j.burns.2012.09.020     Document Type: Review

References (66)

1. R.D. Murray Kenalog and the treatment of hypertrophied scars and keloids in Negroes and Whites Plast Reconstr Surg 31 1963 275 280
2. C. Roques, and L. Teot The use of corticosteroids to treat keloids: a review Int J Low Extrem Wounds 3 2008 137 145
3. B. Berman, and F. Flores The treatment of hypertrophic scars and keloids Eur J Dermatol 8 1998 591 595
4. B. Berman, and H.C. Bieley Keloids J Am Acad Dermatol 33 1995 117 123
5. M.A. Darzi, N.A. Chowdri, S.K. Kaul, and M. Kahn Evaluation of various methods of treating keloids and hypertrophic scars: a 10-year follow up study Br J Plast Surg 45 1992 374 379
6. R. Ogawa The most current algorithms for the treatment and prevention of hypertrophic scars and keloids Plast Reconstr Surg 125 2010 557 568
7. S.A. Doggrell Triamcinolone: new and old indications Expert Opin Pharmacother 2 2001 1177 1186
8. A.W. Lucky Principles of the use of glucocorticosteroids in the growing child Pediatr Dermatol 1 1984 226 235
9. N. Grumbine, C. Dobrowolski, and A. Bernstein Retrospective evaluation of postoperative intralesional steroid injections on wound healing J Foot Ankle Surg 37 1998 135 144
10. E.J. Ross, and D.C. Linch Cushing's syndrome-killing disease: discriminatory value of signs and symptoms aiding early diagnosis Lancet 2 1982 646 649
11. L. Fardet, I. Petersen, and I. Nazareth Risk of cardiovascular events in people prescribed glucocorticoids with iatrogenic Cushing's syndrome: cohort study BMJ 30 2012 345
12. M.J. Finken, and D. Mul Cushing's syndrome and adrenal insufficiency after intradermal triamcinolone acetonide for keloid scars Eur J Pediatr 169 2010 1147 1149
13. J. Newell-Price, P. Trainer, M. Besser, and A. Grossman The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states Endocr Rev 19 1998 647 672
14. L.K. Nieman, B.M.K. Biller, J.W. Findling, J. Newell-Price, M.O. Savage, and P.M. Stewart The diagnosis of Cushing's syndrome: an endocrine society clinical practice guideline J Clin Endocrinol Metab 93 2008 1526 1540
15. B.S. Atiyeh Nonsurgical management of hypertrophic scars: evidence-based therapies, standard practices, and emerging methods Aesthetic Plast Surg 31 2007 468 494
16. L.D. Ketchum, J. Smith, D.W. Robinson, and F.W. Masters The treatment of hypertrophic scar, keloid and scar contracture by triamcinolone acetonide Plast Reconstr Surg 38 1966 209 218
17. L.D. Ketchum, I.K. Cohen, and F.W. Masters Hypertrophic scars and keloids: a collective review Plast Reconstr Surg 53 1974 140 154
18. A.M. Abdel-Fattah Unusual complications of triamcinolone injected keloids: tissue necrosis and systemic corticosteroid effects Br J Plast Surg 29 1976 283
19. J.R. Langston, and S.C. Kolodny Cushing's syndrome associated with the intradermal injection of triamcinolone diacetate J Oral Surg 34 1976 846 849
20. J. Kiil Keloids treated with topical injections of triamcinolone acetonide (kenalog). Immediate and long-term results Scand J Plast Reconstr Surg 11 1977 169 172
21. J.A. Curtis, E. Cormode, B. Laski, J. Toole, and N. Howard Endocrine complications of topical and intralesional corticosteroid therapy Arch Dis Child 57 1982 204 207
22. P.C. Ritota, and A.K. Lo Cushing's syndrome in postburn children following intralesional triamcinolone injection Ann Plast Surg 36 1996 508 511
23. N.A. Chowdri, M. Masarat, A. Mattoo, and M.A. Darzi Keloids and hypertrophic scars: results with intraoperative and serial postoperative corticosteroid injection therapy Aust N Z J Surg 69 1999 655 659
24. S. Teelucksing, B. Balkaran, A. Ganeshmoorthi, and P. Arthur Prolonged childhood Cushing's syndrome secondary to intralesional triamcinolone acetonide Ann Trop Paediatr 22 2002 89 91
25. S. Kumar, R.J. Singh, A.M. Reed, and A.N. Lteif Cushing's syndrome after intra-articular and intradermal administration of triamcinolone acetonide in three pediatric patients Pediatrics 113 2004 1820 1824
26. M.F. Liu, and M. Yencha Cushing's syndrome secondary to intralesional steroid injections of multiple keloid scars Otolaryngol Head Neck Surg 135 2006 960 961
27. R. Hameed, and M.R. Zacharin Cushing syndrome, adrenal suppression and local corticosteroid use J Paediatr Child Health 42 2006 392 394
28. F.X. Margaret Shanthi, K. Ernest, and P. Dhanraj Comparison of intralesional verapamil with intralesional triamcinolone in the treatment of hypertrophic scars and keloids Indian J Dermatol Venereol Leprol 74 2008 343 348
29. T.A. Mustoe, R.D. Cooter, M.H. Gold, F.D. Hobbs, A.A. Ramelet, and P.G. Shakespeare International clinical recommendations on scar management Plast Reconstr Surg 110 2002 560 571
30. S.J. Friedman, D.F. Butler, and M.R. Pittelkow Perilesional linear atrophy and hypopigmentation after intralesional corticosteroid therapy. Report of two cases and review of the literature J Am Acad Dermatol 19 1988 537 541
31. D.A. Sherris, W.F. Larrabee Jr., and C.S. Murakami Management of scar contractures, hypertrophic scars, and keloids Otolaryngol Clin North Am 28 1995 1057 1068
32. B. Berman, M.H. Viera, S. Amini, R. Huo, and I.S. Jones Prevention and management of hypertrophic scars and keloids after burns in children J Craniofac Surg 19 2008 989 1006
33. M.C. Lansang, and L.C. Hustak Glucocorticoid-induced diabetes and adrenal suppression: how to detect and manage them Cleve Clin J Med 78 2011 748 756
34. J.R. Kerrigan, J.D. Veldhuis, S.A. Leyo, A. Iranmanesh, and A.D. Rogol Estimation of daily cortisol production and clearance rates in normal pubertal males by deconvolution analysis J Clin Endocrinol Metab 76 1993 1505 1510
35. B.L. Linder, N.V. Esteban, A.L. Yergey, J.C. Winterer, D.L. Loriaux, and F. Cassorla Cortisol production rate in childhood and adolescence J Pediatr 117 1990 892 896
36. N.V. Esteban, T. Loughlin, A.L. Yergey, J.K. Zawadzki, J.D. Booth, and J.C. Winterer Daily cortisol production rate in man determined by stable isotope dilution/mass spectrometry J Clin Endocrinol Metab 72 1991 39 45
37. L. Axelrod Corticosteroid therapy K.L. Becker, Principles and practice of endocrinology and metabolism 3rd ed. 2001 Lippincott Williams and Wilkins Philadelphia 751 764
38. A.W. Meikle, D.H. Clarke, and F.H. Tyler Cushing syndrome from low doses of dexamethasone a result of slow plasma clearance JAMA 235 1976 1592 1593
39. R. Schlaghecke, E. Kornely, R.T. Santen, and P. Ridderskamp The effect of long-term glucocorticoid therapy on pituitary-adrenal responses to exogenous corticotropin-releasing hormone N Engl J Med 326 1992 226 230
40. R.A. Potter Intralesional triamcinolone and adrenal suppression in Acne vulgaris J Invest Dermatol 57 1971 364 437
41. A.D. McGugan, S. Shuster, and E. Bottoms Adrenal suppression from intradermal triamcinolone J Invest Dermatol 40 1966 271 327
42. M.T. Jarratt, R.F. Spark, and K.A. Arndt The effects of intradermal steroids on the pituitary-adrenal axis and the skin J Invest Dermatol 62 1974 463 466
43. H. Mollmann, P. Rohdewald, E.W. Schmidt, V. Salomon, and H. Derendorf Pharmacokinetics of triamcinolone acetonide and its phosphate ester Eur J Clin Pharmacol 29 1985 85 89
44. A.P. Kelly Medical and surgical therapies for keloids Dermatol Ther 17 2004 212 218
45. J.R. Lindsay, T. Nansel, S. Baid, J. Gumowski, and L.K. Nieman Long-term impaired quality of life in Cushing's syndrome despite initial improvement after surgical remission J Clin Endocrinol Metab 2 2006 447 453
46. J.S. Gondwe, J.E. Davidson, S. Deeley, J. Sills, and A.G. Cleary Secondary Cushing's syndrome in children with juvenile idiopathic arthritis following intra-articular triamcinolone acetonide administration Rheumatology 44 2005 1457 1458
47. B.H. Griffith The treatment of keloids with triamcinolone acetonide Plast Reconstr Surg 38 1966 202 209
48. B.H. Griffith, C.W. Monroe, and P. McKinney A follow-up study on the treatment of keloids with triamcinolone acetonide Plast Reconstr Surg 46 1970 145 150
49. S. Jaworski Kenacort a treatment of hypertrophic scars and keloids in children Pol Przegl Chir 45 1973 145 150 [in Polish]
50. B. Hirshowitz, D. Lerner, and A.R. Moscona Treatment of keloid scars by combined cryosurgery and intralesional corticosteroids Aesthetic Plast Surg 6 1982 153 158
51. W.T. Lawrence In search of the optimal treatment of keloids: report of a series and a review of the literature Ann Plast Surg 27 1991 164 178
52. Y.W. Tang Intra- and postoperative steroid injections for keloids and hypertrophic scars Br J Plast Surg 45 1992 371 373
53. A.M. Layton, J. Yip, and W.J. Cunliffe A comparison of intralesional triamcinolone and cryosurgery in the treatment of acne keloids Br J Dermatol 130 1994 498 501
54. A.P. Sclafani, L. Gordon, M. Chadha, and T. Romo 3rd Prevention of earlobe keloid recurrence with postoperative corticosteroid injections versus radiation therapy: a randomized, prospective study and review of the literature Dermatol Surg 22 1996 569 574
55. Y.C. Kauh, S. Rouda, G. Mondragon, R. Tokarek, M. diLeonardo, and R.S. Tuan Major suppression of pro-alpha1(I) type I collagen gene expression in the dermis after keloid excision and immediate intrawound injection of triamcinolone acetonide J Am Acad Dermatol 37 1997 586 589
56. G. Yosipovitch, M. Widijanti Sugeng, A. Goon, Y.H. Chan, and C.L. Goh A comparison of the combined effect of cryotherapy and corticosteroid injections versus corticosteroids and cryotherapy alone on keloids: a controlled study J Dermatolog Treat 12 2001 87 90
57. G. Muneuchi, S. Suzuki, M. Onodera, O. Ito, Y. Hata, and H.H. Igawa Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients Scand J Plast Reconstr Surg Hand Surg 40 2006 111 116
58. M. Argirova, O. Hadjiski, and A. Victorova Non-operative treatment of hypertrophic scars and keloids after burns in children Ann Burns Fire Disasters 19 2006 80 87
59. D.J. Rosen, M.K. Patel, K. Freeman, and P.R. Weiss A primary protocol for the management of ear keloids: results of excision combined with intraoperative and postoperative steroid injections Plast Reconstr Surg 120 2007 1395 1400
60. P. Donkor Head and neck keloid: treatment by core excision and delayed intralesional injection of steroid J Oral Maxillofac Surg 65 2007 1292 1296
61. E. Koc, E. Arca, B. Surucu, and Z. Kurumlu An open, randomized, controlled, comparative study of the combined effect of intralesional triamcinolone acetonide and onion extract gel and intralesional triamcinolone acetonide alone in the treatment of hypertrophic scars and keloids Dermatol Surg 34 2008 1507 1514
62. A. Darougheh, A. Asilian, and F. Shariati Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars Clin Exp Dermatol 34 2009 219 223
63. M. Hamrick, W. Boswell, and D. Carney Successful treatment of earlobe keloids in the pediatric population J Pediatr Surg 44 2009 286 288
64. J.Y. Jung, M.R. Roh, Y.S. Kwon, and K.Y. Chung Surgery and perioperative intralesional corticosteroid injection for treating earlobe keloids: a Korean experience Ann Dermatol 21 2009 221 225
65. A. Sadeghinia, and S. Sadeghinia Comparison of the efficacy of intralesional triamcinolone acetonide and 5-fluorouracil tattooing for the treatment of keloids Dermatol Surg 38 2012 104 109
66. A.K. Saha, and M. Mukhopadhyay A comparative clinical study on role of 5-flurouracil versus triamcinolone in the treatment of keloids Ind J Surg 2012 1 4