Silica-coated superparamagnetic iron oxide nanoparticles targeting ofEPCs in ischemic brain injury

Biomaterials

Volumn 34, Issue 21, 2013, Pages 4982-4992

  Li, Qianyun ^a   Tang, Guanghui ^b   Xue, Sihan ^b   He, Xiaosong ^b   Miao, Peng ^b   Li, Yaning ^b   Wang, Jixian ^a   Xiong, Liqin ^b   Wang, Yongting ^b   Zhang, Chunfu ^b   Yang, Guo Yuan ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Angiogenesis; EPCs; Ischemia; Magnetic targeting; SPIONs; Stroke

Indexed keywords

ANGIOGENESIS; EPCS; ISCHEMIA; MAGNETIC TARGETING; SPIONS; STROKE;

METAL NANOPARTICLES; SILICA; SUPERPARAMAGNETISM;

MAGNETIC FIELDS;

SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ATROPHY; BRAIN ISCHEMIA; BRAIN SIZE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG TARGETING; ENDOTHELIAL PROGENITOR CELL; HEMISPHERE; IN VITRO STUDY; MAGNETIC FIELD; MALE; MICROVASCULATURE; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ATROPHY; BEHAVIOR, ANIMAL; BRAIN; BRAIN INJURIES; BRAIN ISCHEMIA; CELL MOVEMENT; CELL PROLIFERATION; CELL SEPARATION; DEXTRANS; ENDOTHELIAL CELLS; HUMANS; MAGNETIC FIELDS; MAGNETITE NANOPARTICLES; MICE; NANOPARTICLES; NEOVASCULARIZATION, PHYSIOLOGIC; ORGAN SIZE; SILICON DIOXIDE; STAINING AND LABELING; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MUS;

EID: 84877086237     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.03.030     Document Type: Article

References (59)

1. Fan Y., Shen F., Frenzel T., Zhu W., Ye J., Liu J., et al. Endothelial progenitor cell transplantation improves long-term stroke outcome in mice. Ann Neurol 2010, 67:488-497.
2. Langston J.W. The promise of stem cells in Parkinson disease. JClin Invest 2005, 115:23-25.
3. Manganas L.N., Maletic-Savatic M. Stem cell therapy for central nervous system demyelinating disease. Curr Neurol Neurosci Rep 2005, 5:225-231.
4. Olson S.D., Pollock K., Kambal A., Cary W., Mitchell G.M., Tempkin J., et al. Genetically engineered mesenchymal stem cells as a proposed therapeutic for Huntington's disease. Mol Neurobiol 2012, 45:87-98.
5. De Feo D., Merlini A., Laterza C., Martino G. Neural stem cell transplantation in central nervous system disorders: from cell replacement to neuroprotection. Curr Opin Neurol 2012, 25:322-333.
6. Song M., Kim Y., Ryu S., Song I., Kim S.U., Yoon B.W. MRI tracking of intravenously transplanted human neural stem cells in rat focal ischemia model. Neurosci Res 2009, 64:235-239.
7. Jin K., Sun Y., Xie L., Mao X.O., Childs J., Peel A., et al. Comparison of ischemia-directed migration of neural precursor cells after intrastriatal, intraventricular, or intravenous transplantation in the rat. Neurobiol Dis 2005, 18:366-374.
8. Chen J., Sanberg P.R., Li Y., Wang L., Lu M., Willing A.E., et al. Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke 2001, 32:2682-2688.
9. Gutierrez-Fernandez M., Rodriguez-Frutos B., Alvarez-Grech J., Vallejo-Cremades M.T., Exposito-Alcaide M., Merino J., et al. Functional recovery after hematic administration of allogenic mesenchymal stem cells in acute ischemic stroke in rats. Neuroscience 2011, 175:394-405.
10. Navarro-Sobrino M., Rosell A., Hernandez-Guillamon M., Penalba A., Ribo M., Alvarez-Sabin J., et al. Mobilization, endothelial differentiation and functional capacity of endothelial progenitor cells after ischemic stroke. Microvasc Res 2010, 80:317-323.
11. Park S.J., Moon S.H., Lee H.J., Lim J.J., Kim J.M., Seo J., et al. Acomparison of human cord blood- and embryonic stem cell-derived endothelial progenitor cells in the treatment of chronic wounds. Biomaterials 2013, 34(4):995-1003.
12. Alev C., Ii M., Asahara T. Endothelial progenitor cells: a novel tool for the therapy of ischemic diseases. Antioxid Redox Signal 2011, 15:949-965.
13. Zampetaki A., Kirton J.P., Xu Q. Vascular repair by endothelial progenitor cells. Cardiovasc Res 2008, 78:413-421.
14. Yamaguchi J., Kusano K.F., Masuo O., Kawamoto A., Silver M., Murasawa S., et al. Stromal cell-derived factor-1 effects on exvivo expanded endothelial progenitor cell recruitment for ischemic neovascularization. Circulation 2003, 107:1322-1328.
15. Wu Y., Ip J.E., Huang J., Zhang L., Matsushita K., Liew C.C., et al. Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium. Circ Res 2006, 99:315-322.
16. Smith H.K., Gavins F.N. The potential of stem cell therapy for stroke: is pisces the sign?. FASEB J 2012, 26:2239-2252.
17. Misra V., Ritchie M.M., Stone L.L., Low W.C., Janardhan V. Stem cell therapy in ischemic stroke: role of IV and intra-arterial therapy. Neurology 2012, 79:S207-S212.
18. Li Y., Chopp M., Chen J., Wang L., Gautam S.C., Xu Y.X., et al. Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice. JCereb Blood Flow Metab 2000, 20:1311-1319.
19. Li L., Jiang Q., Ding G., Zhang L., Zhang Z.G., Li Q., et al. Effects of administration route on migration and distribution of neural progenitor cells transplanted into rats with focal cerebral ischemia, an MRI study. JCereb Blood Flow Metab 2010, 30:653-662.
20. Politi L.S., Bacigaluppi M., Brambilla E., Cadioli M., Falini A., Comi G., et al. Magnetic-resonance-based tracking and quantification of intravenously injected neural stem cell accumulation in the brains of mice with experimental multiple sclerosis. Stem Cells 2007, 25:2583-2592.
21. Reddy L.H., Arias J.L., Nicolas J., Couvreu P. Magnetic nanoparticles: design and characterization, toxicity and biocompatibility, pharmaceutical and biomedical applications. Chem Rev 2012, 112:5818-5878.
22. Wang Y., Xu F., Zhang C., Lei D., Tang Y., Xu H., et al. High MR sensitive fluorescent magnetite nanocluster for stem cell tracking in ischemic mouse brain. Nanomedicine: Nanotechnology, Biology, and Medicine 2011, 7:1009-1019.
23. Riegler J., Liew A., Hynes S.O., Ortega D., O'Brien T., Day R.M., et al. Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury. Biomaterials 2013, 34:1987-1994.
24. Song M., Kim Y.J., Kim Y.H., Roh J., Kim S.U., Yoon B.W. Using a neodymium magnet to target delivery of ferumoxide-labeled human neural stem cells in a rat model of focal cerebral ischemia. Hum Gene Ther 2010, 21:603-610.
25. Cheng K., Li T.S., Malliaras K., Davis D.R., Zhang Y., Marban E. Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction. Circ Res 2010, 106:1570-1581.
26. Kyrtatos P.G., Lehtolainen P., Junemann-Ramirez M., Garcia-Prieto A., Price A.N., Martin J.F., et al. Magnetic tagging increases delivery of circulating progenitors in vascular injury. JACC Cardiovasc Interv 2009, 2:794-802.
27. Luciani A., Wilhelm C., Bruneval P., Cunin P., Autret G., Rahmouni A., et al. Magnetic targeting of iron-oxide-labeled fluorescent hepatoma cells to the liver. Eur Radiol 2009, 19:1087-1096.
28. Chen Z., Yin J.J., Zhou Y.T., Zhang Y., Song L., Song M., et al. Dual enzyme-like activities of iron oxide nanoparticles and their implication for diminishing cytotoxicity. ACS Nano 2012, 6:4001-4012.
29. Eggermann J., Kliche S., Jarmy G., Hoffmann K., Mayr-Beyrle U., Debatin K.M., et al. Endothelial progenitor cell culture and differentiation invitro: a methodological comparison using human umbilical cord blood. Cardiovasc Res 2003, 58:478-486.
30. Xu F., Lei D., Du X., Zhang C., Xie X., Yin D. Modification of MR molecular imaging probes with cysteine-terminated peptides and their potential for invivo tumour detection. Contrast Media Mol Imaging 2011, 6:46-54.
31. Zhang C., Xie X., Liang S., Li M., Liu Y., Gu H. Mono-dispersed high magnetic resonance sensitive magnetite nanocluster probe for detection of nascent tumors by magnetic resonance molecular imaging. Nanomedicine: Nanotechnology, Biology, and Medicine 2012, 8:996-1006.
32. Shi W., Nie D., Jin G., Chen W., Xia L., Wu X., et al. BDNF blended chitosan scaffolds for human umbilical cord MSC transplants in traumatic brain injury therapy. Biomaterials 2012, 33:3119-3126.
33. Shoji S., Tang X.Y., Umemura S., Itoh J., Takekoshi S., Shima M., et al. Metastin inhibits migration and invasion of renal cell carcinoma with overexpression of metastin receptor. Eur Urol 2009, 55:441-449.
34. Fan Y., Ye J., Shen F., Zhu Y., Yeghiazarians Y., Zhu W., et al. Interleukin-6 stimulates circulating blood-derived endothelial progenitor cell angiogenesis invitro. JCereb Blood Flow Metab 2008, 28:90-98.
35. Yang G., Chan P.H., Chen J., Carlson E., Chen S.F., Weinstein P., et al. Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke 1994, 25:165-170.
36. Huang J., Li Y., Tang Y., Tang G., Yang G.Y., Wang Y. CXCR4 antagonist AMD3100 protects blood-brain barrier integrity and reduces inflammatory response after focal ischemia in mice. Stroke 2013, 44:190-197.
37. Neri M., Maderna C., Cavazzin C., Deidda-Vigoriti V., Politi L.S., Scotti G., et al. Efficient invitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: relevance for invivo cell tracking. Stem Cells 2008, 26:505-516.
38. Yao Y., Li Y., Ma G., Liu N., Ju S., Jin J., et al. Invivo magnetic resonance imaging of injected endothelial progenitor cells after myocardial infarction in rats. Mol Imaging Biol 2011, 13:303-313.
39. Ma Z.L., Mai X.L., Sun J.H., Ju S.H., Yang X., Ni Y., et al. Inhibited atherosclerotic plaque formation by local administration of magnetically labeled endothelial progenitor cells (EPCs) in a rabbit model. Atherosclerosis 2009, 205:80-86.
40. van Tiel S.T., Wielopolski P.A., Houston G.C., Krestin G.P., Bernsen M.R. Variations in labeling protocol influence incorporation, distribution and retention of iron oxide nanoparticles into human umbilical vein endothelial cells. Contrast Media Mol Imaging 2010, 5:247-257.
41. Lu C.W., Hung Y., Hsiao J.K., Yao M., Chung T.H., Lin Y.S., et al. Bifunctional magnetic silica nanoparticles for highly efficient human stem cell labeling. Nano Lett 2007, 7:149-154.
42. Liu H.M., Wu S.H., Lu C.W., Yao M., Hsiao J.K., Hung Y., et al. Mesoporous silica nanoparticles improve magnetic labeling efficiency in human stem cells. Small 2008, 4:619-626.
43. Tang F., Li L., Chen D. Mesoporous silica nanoparticles: synthesis, biocompatibility and drug delivery. Adv Mater 2012, 24:1504-1534.
44. Lu J., Liong M., Li Z., Zink J.I., Tamanoi F. Biocompatibility, biodistribution, and drug-delivery efficiency of mesoporous silica nanoparticles for cancer therapy in animals. Small 2010, 6:1794-1805.
45. Suh W., Kim K.L., Kim J.M., Shin I.S., Lee Y.S., Lee J.Y., et al. Transplantation of endothelial progenitor cells accelerates dermal wound healing with increased recruitment of monocytes/macrophages and neovascularization. Stem Cells 2005, 23:1571-1578.
46. O E., Lee B.H., Ahn H.Y., Shin J.C., Kim H.K., Kim M., et al. Efficient nonadhesive exvivo expansion of early endothelial progenitor cells derived from CD34+ human cord blood fraction for effective therapeutic vascularization. FASEB J 2011, 25:159-169.
47. Murohara T., Ikeda H., Duan J., Shintani S., Sasaki K., Eguchi H., et al. Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. JClin Invest 2000, 105:1527-1536.
48. Iwaguro H., Yamaguchi J., Kalka C., Murasawa S., Masuda H., Hayashi S., et al. Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration. Circulation 2002, 105:732-738.
49. Rouhl R.P., van Oostenbrugge R.J., Damoiseaux J., Tervaert J.W., Lodder J. Endothelial progenitor cell research in stroke: a potential shift in pathophysiological and therapeutical concepts. Stroke 2008, 39:2158-2165.
50. Asahara T., Kawamoto A., Masuda H. Concise review: circulating endothelial progenitor cells for vascular medicine. Stem Cells 2011, 29:1650-1655.
51. Sobrino T., Hurtado O., Moro M.A., Rodriguez-Yanez M., Castellanos M., Brea D., et al. The increase of circulating endothelial progenitor cells after acute ischemic stroke is associated with good outcome. Stroke 2007, 38:2759-2764.
52. Askari A.T., Unzek S., Popovic Z.B., Goldman C.K., Forudi F., Kiedrowski M., et al. Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy. Lancet 2003, 362:697-703.
53. Schenk S., Mal N., Finan A., Zhang M., Kiedrowski M., Popovic Z., et al. Monocyte chemotactic protein-3 is a myocardial mesenchymal stem cell homing factor. Stem Cells 2007, 25:245-251.
54. Kocher A.A., Schuster M.D., Bonaros N., Lietz K., Xiang G., Martens T.P., et al. Myocardial homing and neovascularization by human bone marrow angioblasts is regulated by IL-8/Gro CXC chemokines. JMol Cell Cardiol 2006, 40:455-464.
55. Tateishi K., Ashihara E., Takehara N., Nomura T., Honsho S., Nakagami T., et al. Clonally amplified cardiac stem cells are regulated by Sca-1 signaling for efficient cardiovascular regeneration. JCell Sci 2007, 120:1791-1800.
56. Urbanek K., Rota M., Cascapera S., Bearzi C., Nascimbene A., De Angelis A., et al. Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival. Circ Res 2005, 97:663-673.
57. Penn M.S., Mangi A.A. Genetic enhancement of stem cell engraftment, survival, and efficacy. Circ Res 2008, 102:1471-1482.
58. Hamasaki T., Tanaka N., Kamei N., Ishida O., Yanada S., Nakanishi K., et al. Magnetically labeled neural progenitor cells, which are localized by magnetic force, promote axon growth in organotypic cocultures. Spine (Phila Pa 1976) 2007, 32:2300-2305.
59. Arbab A.S., Jordan E.K., Wilson L.B., Yocum G.T., Lewis B.K., Frank J.A. Invivo trafficking and targeted delivery of magnetically labeled stem cells. Hum Gene Ther 2004, 15:351-360.