Magnetic Tagging Increases Delivery of Circulating Progenitors in Vascular Injury

JACC: Cardiovascular Interventions

Volumn 2, Issue 8, 2009, Pages 794-802

  Kyrtatos, Panagiotis G ^a,b,d   Lehtolainen, Pauliina ^a   Junemann Ramirez, Manfred ^c   Garcia Prieto, Ana ^e   Price, Anthony N ^a   Martin, John F ^c   Gadian, David G ^b   Pankhurst, Quentin A ^d,e   Lythgoe, Mark F ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^d DAVY FARADAY RESEARCH LABORATORY   (United Kingdom)

^e LONDON CENTRE FOR NANOTECHNOLOGY   (United Kingdom)

Author keywords

angioplasty; endothelial cells; local delivery; magnet; targeting

Indexed keywords

SUPERPARAMAGNETIC IRON OXIDE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE;

ANGIOGENESIS; ANGIOPLASTY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY BLOOD FLOW; ARTICLE; BLOOD VESSEL INJURY; CELL DIFFERENTIATION; CELL LABELING; CELL THERAPY; CELL TRANSFER; CELL VIABILITY; CELLULAR DISTRIBUTION; COMMON CAROTID ARTERY; COMPUTER SIMULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENGRAFTMENT; FINITE ELEMENT ANALYSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MAGNETIC STIMULATION; MAGNETISM; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; STEM CELL; STEM CELL TRANSPLANTATION; TARGET CELL; TECHNOLOGY; VASCULAR ENDOTHELIUM;

ANIMALS; ANTIGENS, CD; APOPTOSIS; CAROTID ARTERY INJURIES; CELL DIFFERENTIATION; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; COMPUTER SIMULATION; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FEASIBILITY STUDIES; FERROSOFERRIC OXIDE; FINITE ELEMENT ANALYSIS; FLOW CYTOMETRY; GLYCOPROTEINS; HUMANS; MAGNETICS; MALE; MICROSCOPY, CONFOCAL; MODELS, CARDIOVASCULAR; NANOPARTICLES; PEPTIDES; PILOT PROJECTS; RATS; RATS, SPRAGUE-DAWLEY; STAINING AND LABELING; STEM CELL TRANSPLANTATION; STEM CELLS; TIME FACTORS;

EID: 68749091036     PISSN: 19368798     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcin.2009.05.014     Document Type: Article

References (46)

1. Hristov M., and Weber C. The therapeutic potential of progenitor cells in ischemic heart disease-past, present and future. Basic Res Cardiol 101 (2006) 1-7
2. Laflamme M.A., and Murry C.E. Regenerating the heart. Nat Biotechnol 23 (2005) 845-856
3. Segers V.F., and Lee R.T. Stem-cell therapy for cardiac disease. Nature 451 (2008) 937-942
4. Abdel-Latif A., Bolli R., Tleyjeh I.M., et al. Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis. Arch Intern Med 167 (2007) 989-997
5. Bartunek J., Dimmeler S., Drexler H., et al., Task Force of the European Society of Cardiology. The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart. Eur Heart J 27 (2006) 1338-1340
6. Pankhurst Q., Connoly J., Jones S., and Dobson J. Applications of magnetic particles in biomedicine. J Phys D Appl Phys 36 (2003) 167-181
7. Bulte J.W., and Kraitchman D.L. Iron oxide MR contrast agents for molecular and cellular imaging. NMR Biomed 17 (2004) 484-499
8. de Vries I., Lesterhuis W.J., Barentsz J.O., et al. Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol 23 (2005) 1407-1413
9. Panizzo R.A., Kyrtatos P.G., Price A.N., Gadian D.G., Ferretti P., and Lythgoe M.F. In vivo magnetic resonance imaging of endogenous neuroblasts labelled with a ferumoxide-polycation complex. Neuroimage 44 (2009) 1239-1246
10. Chertok B., Moffat B.A., David A.E., et al. Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors. Biomaterials 29 (2008) 487-496
11. Dobson J. Magnetic nanoparticles for drug delivery. Drug Dev Res 67 (2006) 55-60
12. Hafeli U.O. Magnetically modulated therapeutic systems. Int J Pharm 277 (2004) 19-24
13. Wilson M.W., Kerlan Jr. R.K., Fidelman N.A., et al. Hepatocellular carcinoma: regional therapy with a magnetic targeted carrier bound to doxorubicin in a dual MR imaging/conventional angiography suite-initial experience with four patients. Radiology 230 (2004) 287-293
14. Consigny P.M., Silverberg D.A., and Vitali N.J. Use of endothelial cells containing superparamagnetic microspheres to improve endothelial cell delivery to arterial surfaces after angioplasty. J Vasc Interv Radiol 10 (1999) 155-163
15. Pislaru S.V., Harbuzariu A., Gulati R., et al. Magnetically targeted endothelial cell localization in stented vessels. J Am Coll Cardiol 48 (2006) 1839-1845
16. Pislaru S.V., Harbuzariu A., Agarwal G., et al. Magnetic forces enable rapid endothelialization of synthetic vascular grafts. Circulation 114 (2006) I314-I318
17. Polyak B., Fishbein I., Chorny M., et al. High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents. Proc Natl Acad Sci U S A 105 (2008) 698-703
18. Muthana M., Scott S.D., Farrow N., et al. A novel magnetic approach to enhance the efficacy of cell-based gene therapies. Gene Ther 15 (2008) 902-910
19. Duda D.G., Cohen K.S., Scadden D.T., and Jain R.K. A protocol for phenotypic detection and enumeration of circulating endothelial cells and circulating progenitor cells in human blood. Nat Protoc 2 (2007) 805-810
20. Peichev M., Naiyer A.J., Pereira D., et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood 95 (2000) 952-958
21. Rafii S., and Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med 9 (2003) 702-712
22. Hristov M., and Weber C. Endothelial progenitor cells in vascular repair and remodeling. Pharmacol Res 58 (2008) 148-151
23. Ward M.R., Stewart D.J., and Kutryk M.J. Endothelial progenitor cell therapy for the treatment of coronary disease, acute MI, and pulmonary arterial hypertension: current perspectives. Catheter Cardiovasc Interv 70 (2007) 983-998
24. Gulati R., Jevremovic D., Peterson T.E., et al. Autologous culture-modified mononuclear cells confer vascular protection after arterial injury. Circulation 108 (2003) 1520-1526
25. Korbling M., Reuben J.M., Gao H., et al. Recombinant human granulocyte-colony-stimulating factor-mobilized and apheresis-collected endothelial progenitor cells: a novel blood cell component for therapeutic vasculogenesis. Transfusion 46 (2006) 1795-1802
26. Quirici N., Soligo D., Caneva L., Servida F., Bossolasco P., and Deliliers G.L. Differentiation and expansion of endothelial cells from human bone marrow CD133(+) cells. Br J Haematol 115 (2001) 186-194
27. Hautot D., Pankhurst Q.A., and Dobson J. Superconducting quantum interference device measurements of dilute magnetic materials in biological samples. Rev Sci Instrum 76 (2005) 045101
28. Mallinson J. One-sided fluxes-a magnetic curiosity?. IEEE Trans Magn 9 (1973) 678-682
29. Berridge M.V., and Tan A.S. Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Arch Biochem Biophys 303 (1993) 474-482
30. Fons P., Herault J.P., Delesque N., Tuyaret J., Bono F., and Herbert J.M. VEGF-R2 and neuropilin-1 are involved in VEGF-A-induced differentiation of human bone marrow progenitor cells. J Cell Physiol 200 (2004) 351-359
31. Santiago F.S., Ishii H., Shafi S., et al. Yin Yang-1 inhibits vascular smooth muscle cell growth and intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-cyclin D1 assembly. Circ Res 101 (2007) 146-155
32. Green C.R., Holloway H., and Walker M.M. Detection of submicroscopic magnetite particles using reflectance mode confocal laser scanning microscopy. Cell Biol Int 25 (2001) 985-990
33. Wilhelm C., Cebers A., Bacri J.C., and Gazeau F. Deformation of intracellular endosomes under a magnetic field. Eur Biophys J 32 (2003) 655-660
34. Garcia-Villalon A.L., Roda J.M., Alvarez F., Gomez B., and Dieguez G. Carotid blood flow in anesthetized rats: effects of carotid ligation and anastomosis. Microsurgery 13 (1992) 258-261
35. Miyashiro J.K., Poppa V., and Berk B.C. Flow-induced vascular remodeling in the rat carotid artery diminishes with age. Circ Res 81 (1997) 311-319
36. Bartunek J., Vanderheyden M., Vandekerckhove B., et al. Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction: feasibility and safety. Circulation 112 (2005) I178-I183
37. Stamm C., Kleine H.D., Choi Y.H., et al. Intramyocardial delivery of CD133+ bone marrow cells and coronary artery bypass grafting for chronic ischemic heart disease: safety and efficacy studies. J Thorac Cardiovasc Surg 133 (2007) 717-725
38. Losordo D.W., Schatz R.A., White C.J., et al. Intramyocardial transplantation of autologous CD34+ stem cells for intractable angina: a phase I/IIa double-blind, randomized controlled trial. Circulation 115 (2007) 3165-3172
39. Erbs S., Linke A., Adams V., et al. Transplantation of blood-derived progenitor cells after recanalization of chronic coronary artery occlusion: first randomized and placebo-controlled study. Circ Res 97 (2005) 756-762
40. Schachinger V., Assmus B., Britten M.B., et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI trial. J Am Coll Cardiol 44 (2004) 1690-1699
41. Charwat S., Gyongyosi M., Lang I., et al. Role of adult bone marrow stem cells in the repair of ischemic myocardium: current state of the art. Exp Hematol 36 (2008) 672-680
42. Roncalli J.G., Tongers J., Renault M.A., and Losordo D.W. Endothelial progenitor cells in regenerative medicine and cancer: a decade of research. Trends Biotechnol 26 (2008) 276-283
43. Hill J.M., Dick A.J., Raman V.K., et al. Serial cardiac magnetic resonance imaging of injected mesenchymal stem cells. Circulation 108 (2003) 1009-1014
44. Hinds K.A., Hill J.M., Shapiro E.M., et al. Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells. Blood 102 (2003) 867-872
45. Faddis M.N., Blume W., Finney J., et al. Novel, magnetically guided catheter for endocardial mapping and radiofrequency catheter ablation. Circulation 106 (2002) 2980-2985
46. Tamaz S., Gourdeau R., Chanu A., Mathieu J.B., and Martel S. Real-time MRI-based control of a ferromagnetic core for endovascular navigation. IEEE Trans Biomed Eng 55 (2008) 1854-1863