N-Alkylated 2,3,3-trimethylindolenines and 2-methylbenzothiazoles. Potential lead compounds in the fight against Saccharomyces cerevisiae infections Dedication in memory of the late Derek Bennett 17-07-1931 to 05-04-2013.

European Journal of Medicinal Chemistry

Volumn 64, Issue , 2013, Pages 222-227

  Tyler, Andrew R ^a   Okoh, Adeyi Okoh ^a   Lawrence, Clare L ^b   Jones, Vicky C ^b   Moffatt, Colin ^a   Smith, Robert B ^a  

^a UNIVERSITY OF CENTRAL LANCASHIRE   (United Kingdom)

^b UNIVERSITY OF CENTRAL LANCASHIRE   (United Kingdom)

Author keywords

2,3,3 Trimethylindolenine; 2 Methylbenzothiazole; Antifungal; Drug design; Structure activity relationship; Yeast

Indexed keywords

2 METHYLBENZOTHIAZOLE; 2,3,3 TRIMETHYLINDOLENINE; AMPHOTERICIN B; ANTIFUNGAL AGENT; BENZOTHIAZOLE DERIVATIVE; FLUCONAZOLE; INDOLE DERIVATIVE; ITRACONAZOLE; TIABENDAZOLE; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; CANDIDA ALBICANS; DRUG SCREENING; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; IMMUNOCOMPROMISED PATIENT; MYCOSIS; NONHUMAN; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE INFECTION; SCHIZOSACCHAROMYCES POMBE;

ANTIFUNGAL AGENTS; BENZOTHIAZOLES; CANDIDA ALBICANS; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84877084677     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.03.031     Document Type: Article

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