Chimeric γc cytokine receptors confer cytokine independent engraftment of human T lymphocytes

Molecular Immunology

Volumn 56, Issue 1-2, 2013, Pages 1-11

  Hunter, Michelle R ^a   Prosser, Megan E ^a   Mahadev, Vaidehi ^a   Wang, Xiuli ^a   Aguilar, Brenda ^a   Brown, Christine E ^a   Forman, Stephen J ^a   Jensen, Michael C ^a,b,c  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

Author keywords

Adoptive immunotherapy; C CR; Chimeric receptor; CTL; Cytokine signaling; IL; REM; TE CM; U

Indexed keywords

CYTOKINE RECEPTOR; GAMMA C CYTOKINE RECEPTOR; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 7 RECEPTOR; INTERLEUKIN 7 RECEPTOR ALPHA; PROTEIN SHC; STAT5 PROTEIN; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; ENGRAFTMENT; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADOPTIVE TRANSFER; ANIMALS; BLOTTING, WESTERN; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; FLOW CYTOMETRY; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; INTERLEUKIN-15; INTERLEUKIN-2 RECEPTOR BETA SUBUNIT; INTERLEUKIN-7; JURKAT CELLS; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; RECEPTORS, INTERLEUKIN-7; RECOMBINANT FUSION PROTEINS; SHC SIGNALING ADAPTOR PROTEINS; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, CYTOTOXIC; TRANSPLANTATION, HETEROLOGOUS;

MUS;

EID: 84877075295     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2013.03.021     Document Type: Article

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