Application of mutated miR-206 target sites enables skeletal muscle-specific silencing of transgene expression of cardiotropic AAV9 vectors

Molecular Therapy

Volumn 21, Issue 5, 2013, Pages 924-933

  Geisler, Anja ^a   Schön, Christian ^b   Größl, Tobias ^a   Pinkert, Sandra ^a   Stein, Elisabeth A ^a   Kurreck, Jens ^a   Vetter, Roland ^b   Fechner, Henry ^a  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM BINDING PROTEIN; MESSENGER RNA; MICRORNA; MICRORNA 1; MICRORNA 122; MICRORNA 206; PARVOVIRUS VECTOR; PROTEIN S100A1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG RESISTANCE; DRUG SENSITIVITY; GENE EXPRESSION; GENE MUTATION; GENE REPRESSION; GENE SILENCING; HEART FAILURE; HEART MUSCLE CELL; IN VIVO STUDY; LIVER; MOUSE; NEWBORN; NONHUMAN; SKELETAL MUSCLE; TISSUE SPECIFICITY; TRANSGENE; VIRAL GENE DELIVERY SYSTEM;

ADENO-ASSOCIATED VIRUS 9;

EID: 84877074221     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2012.276     Document Type: Conference Paper

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