Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections

Archives of Biochemistry and Biophysics

Volumn 535, Issue 2, 2013, Pages 163-176

  D'Antonio, Edward L ^a   Ullman, Buddy ^b   Roberts, Sigrid C ^c   Dixit, Upasna Gaur ^d   Wilson, Mary E ^d   Hai, Yang ^a   Christianson, David W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c PACIFIC UNIVERSITY   (United States)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

Arginase; Leishmaniasis; Metalloenzyme; X ray crystallography

Indexed keywords

ARGINASE; ARGINASE 1; ARGININE DERIVATIVE; HEXANOIC ACID DERIVATIVE; POLYAMINE;

ARTICLE; CATALYSIS; CELL GROWTH; CELL SURVIVAL; CRYSTAL STRUCTURE; ENZYME BINDING; ENZYME SUBSTRATE; LEISHMANIA MEXICANA; LEISHMANIASIS; NONHUMAN; POLYAMINE SYNTHESIS; PRIORITY JOURNAL;

AMINOCAPROIC ACIDS; ANIMALS; ANTIPARASITIC AGENTS; ARGINASE; ARGININE; BORON COMPOUNDS; CRYSTALLOGRAPHY, X-RAY; FEMALE; HUMANS; LEISHMANIA MEXICANA; LEISHMANIASIS, CUTANEOUS; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; ORNITHINE; POLYAMINES; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTOZOAN PROTEINS;

LEISHMANIA MEXICANA; PROTOZOA;

EID: 84877052793     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2013.03.015     Document Type: Article

References (66)

1. P. Desjeux Clin. Dermatol. 14 1996 417 423
2. P. Desjeux Clin. Dermatol. 17 1999 317 325
3. N. Wanasen, and L. Soong Immunol. Res. 41 2008 15 25
4. P. Desjeux Trans. R. Soc. Trop. Med. Hyg. 95 2001 239 243
5. W.D. James, T.G. Berger, and D.M. Elston Andrews' Diseases of the Skin Clinical Dermatology eleventh ed. 2011 Elsevier/Saunders Philadelphia, PA p. 968
6. S. Antinori, E. Gianelli, S. Calattini, E. Longhi, M. Gramiccia, and M. Corbellino Clin. Microbiol. Infect. 11 2005 343 346
7. N.A. Wright, L.E. Davis, K.S. Aftergut, C.A. Parrish, and C.J. Cockerell J. Am. Acad. Dermatol. 58 2008 650 652
8. C. González, O. Wang, S.E. Strutz, C. González-Salazar, V. Sánchez-Cordero, and S. Sarkar PLoS Negl. Trop. Dis. 4 2010 e585 10.1371/journal.pntd.0000585
9. O. Heby, S.C. Roberts, and B. Ullman Biochem. Soc. Trans. 31 2003 415 419
10. O. Heby, L. Persson, and M. Rentala Amino Acids 33 2007 359 366
11. C.J. Bacchi, H.C. Nathan, S.H. Hutner, P.P. McCann, and A. Sjoerdsma Science 210 1980 332 334
12. N.V. Grishin, A.L. Osterman, H.B. Brooks, M.A. Phillips, and E.J. Goldsmith Biochemistry 38 1999 15174 15184
13. K. Kaur, K. Emmett, P.P. McCann, A. Sjoerdsma, and B. Ullman J. Protozool. 33 1986 518 521
14. R.M. Reguera, R.B. Fouce, J.C. Cubría, M.L. Bujidos, and D. Ordóñez Life Sci. 56 1995 223 230
15. L. Gradoni, M.A. Iorio, M. Gramiccia, and S. Orsini Farmaco 44 1989 1157 1166
16. R. Mukhopadhyay, and R. Madhubala Pharmacol. Res. 28 1993 359 365
17. T. Olenyik, C. Gilroy, and B. Ullman Mol. Biochem. Parasitol. 176 2011 109 111
18. J.M. Boitz, P.A. Yates, C. Kline, U. Gaur, M.E. Wilson, B. Ullman, and S.C. Roberts Infect. Immun. 77 2009 756 763
19. C. Gilroy, T. Olenyik, S.C. Roberts, and B. Ullman Infect. Immun. 79 2011 109 111
20. D.E. Ash, J.D. Cox, and D.W. Christianson Arginase: a binuclear manganese metalloenzyme Manganese and Its Role in Biological Processes A. Sigel, H. Sigel, Metal Ions in Biological Systems vol. 37 1999 M. Dekker New York 407 428
21. D.W. Christianson Acc. Chem. Res. 38 2005 191 201
22. P. Vincendeau, A.P. Gobert, S. Daulouède, D. Moynet, and M.D. Mossalayi Trends Parasitol. 19 2003 9 12
23. P. Das, A. Lahiri, and D. Chakravortty PLoS Pathog. 6 2010 e10000899 10.1371/journal.ppat.1000899
24. S.C. Roberts, M.J. Tancer, M.R. Polinsky, K.M. Gibson, O. Heby, and B. Ullman J. Biol. Chem. 279 2004 23668 23678
25. M.F. da Silva, R.A. Zampieri, S.M. Muxel, S.M. Beverley, and L.M. Floeter-Winter PLoS One 7 2012 e34022
26. R.M. Reguera, R. Balaña-Fouce, M. Showalter, S. Hickerson, and S.M. Beverley Mol. Biochem. Parasitol. 165 2009 48 56
27. H.M. Muleme, R.M. Reguera, A. Berard, R. Azinwi, P. Jia, I.B. Okwor, S. Beverley, and J.E. Uzonna J. Immunol. 183 2009 8068 8076
28. J. Custot, C. Moali, M. Brollo, J.L. Boucher, M. Delaforge, D. Mansuy, J.P. Tenu, and J.L. Zimmermann J. Am. Chem. Soc. 119 1997 4086 4087
29. V. Iniesta, L.C. Gómez-Nieto, and I. Corraliza J. Exp. Med. 193 2001 777 783
30. P. Kropf, J.M. Fuentes, E. Fähnrich, L. Arpa, S. Herath, V. Weber, G. Soler, A. Celada, M. Modolell, and I. Müller FASEB J. 19 2005 1000 1002
31. V. Iniesta, J. Carcelén, I. Molano, P.M. Peixoto, E. Redondo, P. Parra, M. Mangas, I. Monroy, M.L. Campo, C.G. Nieto, and I. Corraliza Infect. Immun. 73 2005 6085 6090
32. M. Aslett, C. Aurrecoechea, M. Berriman, J. Brestelli, B.P. Brunk, M. Carrington, D.P. Depledge, S. Fischer, B. Gajria, X. Gao, M.J. Gardner, A. Gingle, G. Grant, O.S. Harb, M. Heiges, C. Hertz-Fowler, R. Houston, F. Innamorato, J. Iodice, J.C. Kissinger, E. Kraemer, W. Li, F.J. Logan, J.A. Miller, S. Mitra, P.J. Myler, V. Nayak, C. Pennington, I. Phan, D.F. Pinney, G. Ramasamy, M.B. Rogers, D.S. Roos, C. Ross, D. Sivam, D.F. Smith, G. Srinivasamoorthy, C.J. Stoeckert Jr., S. Subramanian, R. Thibodeau, A. Tivey, C. Treatman, G. Velarde, and H. Wang Nucleic Acids Res. 38 2010 D457 D462
33. E.R. da Silva, M.F.L. da Silva, H. Fischer, R.A. Mortara, M.G. Mayer, K. Framesqui, A.M. Silber, and L.M. Floeter-Winter Mol. Biochem. Parasitol. 159 2008 104 111
34. E. Riley, S.C. Roberts, and B. Ullman Int. J. Parasitol. 41 2011 545 552
35. R. Baggio, D. Elbaum, Z.F. Kanyo, P.J. Carroll, R.C. Cavalli, D.E. Ash, and D.W. Christianson J. Am. Chem. Soc. 119 1997 8107 8108
36. L. Di Costanzo, G. Sabio, A. Mora, P.C. Rodriquez, A.C. Ochoa, F. Centeno, and D.W. Christianson Proc. Natl. Acad. Sci. USA 102 2005 13058 13063
37. N.N. Kim, J.D. Cox, R.F. Baggio, F.A. Emig, S.K. Mistry, S.L. Harper, D.W. Speicher, S.M. Morris, D.E. Ash, A. Traish, and D.W. Christianson Biochemistry 40 2001 2678 2688
38. L. Di Costanzo, M. Ilies, K.J. Thorn, and D.W. Christianson Arch. Biochem. Biophys. 496 2010 101 108
39. J.J. Ward, J.S. Sodhi, L.J. McGuffin, B.F. Buxton, and D.T. Jones J. Mol. Biol. 337 2004 635 645
40. Z. Otwinowski, and W. Minor Methods Enzymol. 276 1997 307 326
41. T.O. Yeates Methods Enzymol. 276 1997 344 358
42. A.T. Brünger, P.D. Adams, G.M. Clore, W.L. Delano, P. Gros, R.W. Grosse-Kunstleve, J.S. Jiang, J. Kuszewski, N. Nilges, N.S. Pannu, R.J. Read, L.M. Rice, T. Simonson, and G.L. Warren Acta Crystallogr. D54 1998 905 921
43. A.J. McCoy, R.W. Grosse-Kunstleve, L.C. Storoni, and R.J. Read Acta Crystallogr. D61 2005 458 464
44. Collaborative Computational Project, Number 4 Acta Crystallogr. D50 1994 760 763
45. E.L. D'Antonio, and D.W. Christianson Biochemistry 50 2011 8018 8027
46. P. Emsley, and K. Cowtan Acta Crystallogr. D60 2004 2126 2132
47. R.A. Laskowski, M.W. MacArthur, D.S. Moss, and J.M. Thornton J. Appl. Crystallogr. 26 1993 283 291
48. G.J. Kleywegt, J.Y. Zou, M. Kjeldgaard, and T.A. Jones Around O M.G. Rossmann, E. Arnold, International Tables of Crystallography 2001 Kluwer Academic Publishers Dordrecht, The Netherlands 353 356 pp. 366-367
49. W.L. DeLano MacPyMOL: A PyMOL-based molecular graphics application for MacOS X 2007 DeLano Scientific LLC Palo Alto, California
50. N.A. Baker, D. Sept, S. Joseph, M.J. Holst, and J.A. McCammon Proc. Natl. Acad. Sci. USA 98 2001 10037 10041
51. T.J. Dolinsky, J.E. Nielson, J.A. McCammon, and N.A. Baker Nucleic Acids Res. 32 2004 W665 W667
52. M.H. Olsson, C.R. Søndergaard, M. Rostkowski, and J.H. Jensen J. Chem. Theory Comput. 7 2011 525 537
53. U. Gaur, S.C. Roberts, R.P. Dalvi, I. Corraliza, B. Ullman, and M.E. Wilson J. Immunol. 179 2007 8446 8453
54. L. Di Costanzo, M.E. Pique, and D.W. Christianson J. Am. Chem. Soc. 129 2007 6388 6389
55. E. Krissinel, and K. Henrick J. Mol. Biol. 372 2007 774 797
56. J.D. Cox, N.N. Kim, A.M. Traish, and D.W. Christianson Nat. Struct. Biol. 6 1999 1043 1047
57. D.P. Dowling, M. Ilies, K.L. Olszewski, S. Portugal, M.M. Mota, M. Llinás, and D.W. Christianson Biochemistry 49 2010 5600 5608
58. M. Ilies, L. Di Costanzo, D.P. Dowling, K.J. Thorn, and D.W. Christianson J. Med. Chem. 54 2011 5432 5443
59. F.R. Opperdoes Annu. Rev. Microbiol. 41 1987 127 151
60. P.A. Michels, F. Bringaud, M. Herman, and V. Hannaert Biochim. Biophys. Acta 1763 2006 1463 1477
61. C.-Y. Kim, P.P. Chandra, A. Jain, and D.W. Christianson J. Am. Chem. Soc. 123 2001 9620 9627
62. P. Auffinger, F.A. Hays, E. Westhof, and P.S. Ho Proc. Natl. Acad. Sci. USA 101 2004 16789 16794
63. R. Wilcken, M.O. Zimmermann, A. Lange, A.C. Joerger, and F.M. Boeckler J. Med. Chem. 56 2013 1363 1388
64. D. Frishman, and P. Argos Proteins: Struct. Funct. Genet. 23 1995 566 579
65. M. Heinig, and D. Frishman Nucleic Acids Res. 32 2004 W500 W502
66. P. Gouet, E. Courcelle, D.I. Stuart, and F. Métoz Bioinformatics 15 1999 305 308