Study on the association of SNPs of MMP-2 and TIMP-2 genes with the risk of endometriosis and adenomyosis

Chinese Journal of Medical Genetics

Volumn 25, Issue 3, 2008, Pages 280-283

  Zhao, Xi Wa ^a   Li, Yan ^b   Wang, Na ^b   Zhao, Jian ^a   Li, Xiu Lan ^a   Liu, Qing ^a   Jia, Jing Hui ^a   Yang, Zhi Feng ^a   Kang, Shan ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Hebei Cancer Institute   (China)

Author keywords

Adenomyosis; Endometriosis; Genetic polymorphism; Matrix metalloproteinase 2; Tissue inhibitor of metalloproteinase 2

Indexed keywords

GELATINASE A; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ADENOMYOSIS; ARTICLE; CONTROLLED STUDY; ENDOMETRIOSIS; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC LINKAGE; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ENDOMETRIOSIS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MATRIX METALLOPROTEINASE 2; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 46749136063     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Chung HW, Lee JY, Moon HS, et al. Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium. Fertil Steril, 2002, 78:787-795.
2. Price SJ, Greaves DR, Watkins H. Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: role of Sp1 in allele-specific transcriptional regulation. J Biol Chem, 2000, 276:7549-7558.
3. Yu C, Zhou Y, Miao X, et al. Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer. Cancer Res, 2004, 64:7622-7628.
4. DeClerck YA, Darville MI, Eeckhout Y, et al. Characterization of the promoter of the gene encoding human tissue inhibitor of metalloproteinases-2 (TIMP-2). Gene, 1994, 139:185-191.
5. Holla LI, Fassmann A, Vasku A, et al. Genetic variations in the human gelatinase A (matrix metalloproteinase-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis. J Periodontol, 2005, 76:1056-1060.
6. Rollin J, Regina S, Vourc'h P, et al. Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer. Lung Cancer, 2007, 56:273-280.
7. Vairaktaris E, Yapijakis C, Yiannopoulos A, et al. Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans. Oncol Rep, 2007, 17: 963-968.
8. Wu CY, Wu MS, Chen YJ, et al. Clinic pathological significance of MMP-2 and TiMP-2 genotypes in gastric cancer. Eur J Cancer, 2007, 43:799-808.
9. Zhou Y, Yu C, Miao X, et al. Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes. Carcinogenesis , 2003, 25:399-404.
10. Zhou Y, Yu C, Miao X, et al. Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility. Carcinogenesis, 2005, 26:1117-1121.
11. Hirano K, Sakamoto T, Uchida Y, et al. Tissue inhibitor of metalloproteinases-2 gene polymorphisms in chronic obstructive pulmonary disease. Eur Respir J, 2001, 18:748-752.
12. Hegab AE, Sakamoto T, Uchida Y, et al. Association analysis of tissue inhibitor of metalloproteinase 2 gene polymorphisms with COPD in Egyptians. Respir Med, 2005, 99:107-110.