Acute myocardial infarction induced functional cardiomyocytes to re-enter the cell cycle

American Journal of Translational Research

Volumn 5, Issue 3, 2013, Pages 327-335

  Li, Yongjun ^a   Hu, Shengda ^a   Ma, Genshan ^a   Yao, Yuyu ^a   Yan, Gaoliang ^a   Chen, Jia ^b   Li, Yefei ^a   Zhang, Zhuoli ^c  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

^b INOVA FAIRFAX HOSPITAL   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Acute myocardial infarction; Cell cycle; Cyclin A2; Mitosis

Indexed keywords

AURORA B KINASE; CYCLIN A2; HISTONE H3; KI 67 ANTIGEN; PHOSPHO HISTONE H3; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; CORRELATION COEFFICIENT; GENE EXPRESSION; HEART MUSCLE CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MITOSIS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; SHAM PROCEDURE; TISSUE SECTION; TWO DIMENSIONAL ECHOCARDIOGRAPHY; WESTERN BLOTTING;

RATTUS;

EID: 84877036822     PISSN: None     EISSN: 19438141     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Kiessling A, Fussel S, Wehner R, Bachmann M, Wirth MP, Rieber EP and Schmitz M. Advances in specific immunotherapy for prostate cancer. Eur Urol 2008; 53: 694-708.
2. Hsieh PC, Segers VF, Davis ME, MacGillivray C, Gannon J, Molkentin JD, Robbins J and Lee RT. Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nat Med 2007; 13: 970-974.
3. Beltrami AP, Urbanek K, Kajstura J, Yan SM, Finato N, Bussani R, Nadal-Ginard B, Silvestri F, Leri A, Beltrami CA and Anversa P. Evidence that human cardiac myocytes divide after myocardial infarction. N Engl J Med 2001; 344: 1750-1757.
4. Kajstura J, Leri A, Finato N, Di Loreto C, Beltrami CA and Anversa P. Myocyte proliferation in end-stage cardiac failure in humans. Proc Natl Acad Sci U S A 1998; 95: 8801-8805.
5. van Amerongen MJ, Diehl F, Novoyatleva T, Patra C and Engel FB. E2F4 is required for cardiomyocyte proliferation. Cardiovasc Res 2010; 86: 92-102.
6. Novoyatleva T, Diehl F, van Amerongen MJ, Patra C, Ferrazzi F, Bellazzi R and Engel FB. TWEAK is a positive regulator of cardiomyocyte proliferation. Cardiovasc Res 2010; 85: 681690.
7. Pagano M, Pepperkok R, Verde F, Ansorge W and Draetta G. Cyclin A is required at two points in the human cell cycle. EMBO J 1992; 11: 961-971.
8. Sherr CJ and Roberts JM. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 1995; 9: 1149-1163.
9. Woo YJ, Panlilio CM, Cheng RK, Liao GP, Atluri P, Hsu VM, Cohen JE and Chaudhry HW. Therapeutic delivery of cyclin A2 induces myocardial regeneration and enhances cardiac function in ischemic heart failure. Circulation 2006; 114: I206-213.
10. Scholzen T and Gerdes J. The Ki-67 protein: from the known and the unknown. J Cell Physiol 2000; 182: 311-322.
11. Wei Y, Mizzen CA, Cook RG, Gorovsky MA and Allis CD. Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena. Proc Natl Acad Sci U S A 1998; 95: 7480-7484.
12. Youn TJ, Piao H, Kwon JS, Choi SY, Kim HS, Park DG, Kim DW, Kim YG and Cho MC. Effects of the calcineurin dependent signaling pathway inhibition by cyclosporin A on early and late cardiac remodeling following myocardial infarction. Eur J Heart Fail 2002; 4: 713-718.
13. Asif M, Egan J, Vasan S, Jyothirmayi GN, Masurekar MR, Lopez S, Williams C, Torres RL, Wagle D, Ulrich P, Cerami A, Brines M and Regan TJ. An advanced glycation endproduct crosslink breaker can reverse age-related increases in myocardial stiffness. Proc Natl Acad Sci U S A 2000; 97: 2809-2813.
14. Lopez Y, Lutjemeier B, Seshareddy K, Trevino EM, Hageman KS, Musch TI, Borgarelli M and Weiss ML. Wharton's Jelly or Bone Marrow Mesenchymal Stromal Cells Improve Cardiac Function Following Myocardial Infarction for More Than 32 Weeks in a Rat Model: A Preliminary Report. Curr Stem Cell Res Ther 2013; 8: 46-59.
15. Yoshizumi M, Lee WS, Hsieh CM, Tsai JC, Li J, Perrella MA, Patterson C, Endege WO, Schlegel R and Lee ME. Disappearance of cyclin A correlates with permanent withdrawal of cardiomyocytes from the cell cycle in human and rat hearts. J Clin Invest 1995; 95: 2275-2280.
16. Kajstura J, Zhang X, Reiss K, Szoke E, Li P, Lagrasta C, Cheng W, Darzynkiewicz Z, Olivetti G and Anversa P. Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing-induced cardiomyopathy in rats. Circ Res 1994; 74: 383-400.
17. Hall PA, McKee PH, Menage HD, Dover R and Lane DP. High levels of p53 protein in UV-irradiated normal human skin. Oncogene 1993; 8: 203-207.
18. Hall PA and Woods AL. Immunohistochemical markers of cellular proliferation: achievements, problems and prospects. Cell Tissue Kinet 1990; 23: 505-522.
19. MacCallum DE and Hall PA. The location of pKi67 in the outer dense fibrillary compartment of the nucleolus points to a role in ribosome biogenesis during the cell division cycle. J Pathol 2000; 190: 537-544.
20. MacCallum DE and Hall PA. The biochemical characterization of the DNA binding activity of pKi67. J Pathol 2000; 191: 286-298.
21. Olivetti G, Cigola E, Maestri R, Corradi D, Lagrasta C, Gambert SR and Anversa P. Aging, cardiac hypertrophy and ischemic cardiomyopathy do not affect the proportion of mononucleated and multinucleated myocytes in the human heart. J Mol Cell Cardiol 1996; 28: 1463-1477.
22. Kajstura J, Zhang X, Liu Y, Szoke E, Cheng W, Olivetti G, Hintze TH and Anversa P. The cellular basis of pacing-induced dilated cardiomyopathy. Myocyte cell loss and myocyte cellular reactive hypertrophy. Circulation 1995; 92: 2306-2317.
23. Reiss K, Cheng W, Ferber A, Kajstura J, Li P, Li B, Olivetti G, Homcy CJ, Baserga R and Anversa P. Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice. Proc Natl Acad Sci U S A 1996; 93: 8630-8635.
24. Agah R, Kirshenbaum LA, Abdellatif M, Truong LD, Chakraborty S, Michael LH and Schneider MD. Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo. J Clin Invest 1997; 100: 2722-2728.
25. Akli S, Zhan S, Abdellatif M and Schneider MD. E1A can provoke G1 exit that is refractory to p21 and independent of activating cdk2. Circ Res 1999; 85: 319-328.
26. Suzuki G, Lee TC, Fallavollita JA and Canty JM Jr. Adenoviral gene transfer of FGF-5 to hibernating myocardium improves function and stimulates myocytes to hypertrophy and reenter the cell cycle. Circ Res 2005; 96: 767-775.
27. Parodi O, De Maria R, Oltrona L, Testa R, Sambuceti G, Roghi A, Merli M, Belingheri L, Accinni R, Spinelli F, Pellegrini A and Baroldi G. Myocardial blood flow distribution in patients with ischemic heart disease or dilated cardiomyopathy undergoing heart transplantation. Circulation 1993; 88: 509-522.
28. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, Pickel J, McKay R, Nadal-Ginard B, Bodine DM, Leri A and Anversa P. Bone marrow cells regenerate infarcted myocardium. Nature 2001; 410: 701-705.
29. Lagasse E, Connors H, Al-Dhalimy M, Reitsma M, Dohse M, Osborne L, Wang X, Finegold M, Weissman IL and Grompe M. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000; 6: 1229-1234.
30. Rieder CL. The formation, structure, and composition of the mammalian kinetochore and kinetochore fiber. Int Rev Cytol 1982; 79: 1-58.
31. Antonio C, Ferby I, Wilhelm H, Jones M, Karsenti E, Nebreda AR and Vernos I. Xkid, a chromokinesin required for chromosome alignment on the metaphase plate. Cell 2000; 102: 425-435.
32. Kuhn B, del Monte F, Hajjar RJ, Chang YS, Lebeche D, Arab S and Keating MT. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nat Med 2007; 13: 962-969.
33. Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K, Leri A, Kajstura J, Nadal-Ginard B and Anversa P. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003; 114: 763-776.
34. Fallon J, Reid S, Kinyamu R, Opole I, Opole R, Baratta J, Korc M, Endo TL, Duong A, Nguyen G, Karkehabadhi M, Twardzik D, Patel S and Loughlin S. In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain. Proc Natl Acad Sci U S A 2000; 97: 14686-14691.
35. Oh H, Bradfute SB, Gallardo TD, Nakamura T, Gaussin V, Mishina Y, Pocius J, Michael LH, Behringer RR, Garry DJ, Entman ML and Schneider MD. Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci U S A 2003; 100: 12313-12318.
36. Matsuura K, Nagai T, Nishigaki N, Oyama T, Nishi J, Wada H, Sano M, Toko H, Akazawa H, Sato T, Nakaya H, Kasanuki H and Komuro I. Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes. J Biol Chem 2004; 279: 11384-11391.
37. Martin CM, Meeson AP, Robertson SM, Hawke TJ, Richardson JA, Bates S, Goetsch SC, Gallardo TD and Garry DJ. Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart. Dev Biol 2004; 265: 262-275.
38. Laugwitz KL, Moretti A, Lam J, Gruber P, Chen Y, Woodard S, Lin LZ, Cai CL, Lu MM, Reth M, Platoshyn O, Yuan JX, Evans S and Chien KR. Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature 2005; 433: 647-653.
39. Bergmann O, Bhardwaj RD, Bernard S, Zdunek S, Barnabe-Heider F, Walsh S, Zupicich J, Alkass K, Buchholz BA, Druid H, Jovinge S and Frisen J. Evidence for cardiomyocyte renewal in humans. Science 2009; 324: 98-102.
40. Bicknell KA, Coxon CH and Brooks G. Forced expression of the cyclin B1-CDC2 complex induces proliferation in adult rat cardiomyocytes. Biochem J 2004; 382: 411-416.
41. Regula KM, Rzeszutek MJ, Baetz D, Seneviratne C and Kirshenbaum LA. Therapeutic opportunities for cell cycle re-entry and cardiac regeneration. Cardiovasc Res 2004; 64: 395401.
42. Regula KM and Kirshenbaum LA. Breaking down cell-cycle barriers in the adult heart. Circ Res 2004; 94: 1524-1526.
43. Soonpaa MH and Field LJ. Survey of studies examining mammalian cardiomyocyte DNA synthesis. Circ Res 1998; 83: 15-26.