Acetylcholinesterase Inhibitors Reduce Neuroinflammation and -Degeneration in the Cortex and Hippocampus of a Surgery Stress Rat Model

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Kalb, Alexander ^a   von Haefen, Clarissa ^a   Sifringer, Marco ^a   Tegethoff, Annalena ^a   Paeschke, Nadine ^a   Kostova, Mariya ^a   Feldheiser, Aarne ^a   Spies, Claudia D ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINESTERASE INHIBITOR; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; MELOXICAM; NEOSTIG; NEOSTIGMINE; PHYSOSTIGMINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN DEGENERATION; BRAIN SLICE; CHOLINERGIC ACTIVITY; CHOLINERGIC TRANSMISSION; CONTROLLED STUDY; CYTOMETRY; DRUG ACTIVITY; ENZYME ACTIVITY; HIPPOCAMPUS; MALE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; POSTOPERATIVE COGNITIVE DYSFUNCTION; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPECTROFLUOROMETRY; SPLEEN; SURGICAL STRESS; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CEREBRAL CORTEX; CHOLINESTERASE INHIBITORS; DRUG EVALUATION, PRECLINICAL; HIPPOCAMPUS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MALE; NEOSTIGMINE; NEURODEGENERATIVE DISEASES; PHYSOSTIGMINE; POSTOPERATIVE COMPLICATIONS; RATS; RATS, WISTAR; SPLEEN; STRESS, PHYSIOLOGICAL; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS; RATTUS NORVEGICUS;

EID: 84877032665     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062679     Document Type: Article

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