Synthesis, antifungal and cytotoxic activities of 2-aryl-3-((piperidin-1- yl)ethyl)thiazolidinones

European Journal of Medicinal Chemistry

Volumn 64, Issue , 2013, Pages 74-80

  Kunzler, Alice ^a   Neuenfeldt, Patrícia D ^a   Das Neves, Adriana M ^a   Pereira, Claudio M P ^a   Marques, Gabriela H ^a   Nascente, Patrícia S ^a   Fernandes, Maureen H V ^a   Hübner, Silvia O ^a   Cunico, Wilson ^a  

^a FEDERAL UNIVERSITY OF PELOTAS   (Brazil)

Author keywords

Antifungal activity; Cytotoxicity; One pot reaction; Rhodotorula sp; Thiazolidinones

Indexed keywords

2 (2 CHLOROPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (2 FLUOROPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (2 METHOXYPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (2 NITROPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (2,6 DICHLOROPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL] THIAZDOLIDIN 4 ONE; 2 (3 CHLOROPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (3 FLUOROPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (3 HYDROXYPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (3 METHOXYPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (3 NITROPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (4 CHLOROPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (4 FLUOROPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (4 HYDROXYPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (4 METHOXYPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 (4 NITROPHENYL) 3 [2 (PIPERIDIN 1 YL)ETHYL]THIAZOLIDIN 4 ONE; 2 ARYL 3 [(PIPERIDIN 1 YL)ETHYL]THIAZOLIDINONE DERIVATIVE; 3 [2 (PIPERIDIN 1 YL)ETHYL]2 4 TOLYLTHIAZOLIDIN 4 ONE; 4 THIAZOLIDINONE DERIVATIVE; ANTIFUNGAL AGENT; FLUCONAZOLE; HYDROGEN; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CANDIDA PARAPSILOSIS; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VIABILITY; CONTROLLED STUDY; CRYPTOCOCCUS LAURENTII; CYTOTOXICITY; DRUG SYNTHESIS; GEOTRICHUM; MASS FRAGMENTOGRAPHY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ONE POT SYNTHESIS; PICHIA GUILLIERMONDII; PROTON NUCLEAR MAGNETIC RESONANCE; RHODOTORULA; TRICHOSPORON ASAHII; VERO CELL;

ANIMALS; ANTIFUNGAL AGENTS; CELL SURVIVAL; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; DOSE-RESPONSE RELATIONSHIP, DRUG; FUNGI; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PIPERIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINES; VERO CELLS;

EID: 84877028612     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.03.030     Document Type: Article

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