Piecewise nonlinear mixed-effects models for modeling cardiac function and assessing treatment effects

Computer Methods and Programs in Biomedicine

Volumn 110, Issue 3, 2013, Pages 240-252

  Jang, Hyejeong ^a   Conklin, Daniel J ^b   Kong, Maiying ^a  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

Cardiac function; Change point model; Ischemia reperfusion; Mixed effects model; Piecewise nonlinear mixed effects model

Indexed keywords

CARDIAC FUNCTIONS; CHANGE-POINT MODELS; GLUTATHIONE S-TRANSFERASE P1; ISCHEMIA REPERFUSION; ISCHEMIA/REPERFUSION-INDUCED INJURIES; MIXED-EFFECTS MODELS; NONLINEAR MIXED EFFECTS; REPEATED MEASUREMENTS;

GENETIC ENGINEERING; GRAPHICAL USER INTERFACES; HEART; MAMMALS;

PHYSIOLOGICAL MODELS;

GLUTATHIONE TRANSFERASE P1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CORONARY ARTERY BLOOD FLOW; GENE DELETION; GENE INACTIVATION; GENETIC ENGINEERING; GROWTH CURVE; GROWTH RATE; HEART FUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE REPERFUSION; HEART RATE; MODEL; MOUSE; NONHUMAN; PIECEWISE NONLINEAR MIXED EFFECT MODEL; REPERFUSION INJURY; RESPONSE VARIABLE; VARIANCE; WILD TYPE;

ANIMALS; BLOOD PRESSURE; CORONARY CIRCULATION; GLUTATHIONE S-TRANSFERASE PI; HEART RATE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, CARDIOVASCULAR; MYOCARDIAL REPERFUSION INJURY; NONLINEAR DYNAMICS; VENTRICULAR FUNCTION, LEFT;

EID: 84877026524     PISSN: 01692607     EISSN: 18727565     Source Type: Journal    
DOI: 10.1016/j.cmpb.2012.11.007     Document Type: Article

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