Myofilament calcium de-sensitization and contractile uncoupling prevent pause-triggered ventricular tachycardia in mouse hearts with chronic myocardial infarction

Journal of Molecular and Cellular Cardiology

Volumn 60, Issue 1, 2013, Pages 8-15

  Venkataraman, Raghav ^b   Baldo, Marcelo Perim ^a   Hwang, Hyun Seok ^a   Veltri, Tiago ^c   Pinto, Jose Renato ^c   Baudenbacher, Franz J ^b   Knollmann, Björn C ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Blebbistatin; Chronic MI; Mouse hearts; Myofilament Ca sensitivity; Triggered arrhythmia; Ventricular tachycardia

Indexed keywords

BLEBBISTATIN; CALCIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR RISK; CELL FUNCTION; CELLULAR PARAMETERS; CHRONIC DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DESENSITIZATION; DISEASE ACTIVITY; DISEASE CONTROL; DISEASE EXACERBATION; DISEASE PREDISPOSITION; DISEASE SEVERITY; ECHOCARDIOGRAPHY; EXTRASYSTOLE; HEART; HEART ARRHYTHMIA; HEART CONTRACTION; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE CONTRACTION; HEART MUSCLE CONTRACTILE UNCOUPLING; HEART MUSCLE CONTRACTILITY; HEART PACING; HEART RATE; HEART STIMULATION; HEART VENTRICLE TACHYCARDIA; ISOLATED HEART; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MOUSE; MYOFILAMENT; MYOFILAMENT SENSITIVITY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; TISSUE STRUCTURE;

ANIMALS; CALCIUM; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; MALE; MICE; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOFIBRILS; TACHYCARDIA, VENTRICULAR;

MURINAE; MUS;

EID: 84877022546     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.03.022     Document Type: Article

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