Panoramic imaging reveals basic mechanisms of induction and termination of ventricular tachycardia in rabbit heart with chronic infarction: Implications for low-voltage cardioversion

Heart Rhythm

Volumn 6, Issue 1, 2009, Pages 87-97

  Ripplinger, Crystal M ^a   Lou, Qing ^a   Li, Wenwen ^a   Hadley, Jennifer ^a   Efimov, Igor R ^a  

^a WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

Author keywords

Cardioversion; Infarction; Optical mapping; Ventricular tachycardia

Indexed keywords

BLEBBISTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR RISK; CARDIOVERSION; CONTROLLED STUDY; ELECTRODE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART VENTRICLE TACHYCARDIA; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; CHRONIC DISEASE; DIAGNOSTIC IMAGING; DISEASE MODELS, ANIMAL; ELECTRIC COUNTERSHOCK; FEMALE; HEART RATE; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; IMAGING, THREE-DIMENSIONAL; MALE; MYOCARDIAL INFARCTION; RABBITS; TACHYCARDIA, VENTRICULAR;

EID: 58049190516     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2008.09.019     Document Type: Article

References (35)

1. Callans D.J., Josephson M.E., Zipes D.P., et al. Ventricular tachycardia in patients with coronary artery disease. Cardiac Electrophysiology: From Cell to Bedside (2004), Saunders, Philadelphia, PA 569-574
2. Zheng Z.J., Croft J.B., Giles W.H., et al. Sudden cardiac death in the United States, 1989 to 1998. Circulation 104 (2001) 2158-2163
3. Antiarrhythmics versus Implantable Defibrillators (AVID) Investigators. A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. N Engl J Med 337 (1997) 1576-1583
4. Buxton A.E., Lee K.L., Fisher J.D., et al. A randomized study of the prevention of sudden death in patients with coronary artery disease. Multicenter Unsustained Tachycardia Trial Investigators. N Engl J Med 341 (1999) 1882-1890
5. Cabo C., Yao J., Boyden P.A., et al. Heterogeneous gap junction remodeling in reentrant circuits in the epicardial border zone of the healing canine infarct. Cardiovasc Res 72 (2006) 241-249
6. Ciaccio E.J., Costeas C., Coromilas J., et al. Static relationship of cycle length to reentrant circuit geometry. Circulation 104 (2001) 1946-1951
7. Ohara T., Ohara K., Cao J.M., et al. Increased wave break during ventricular fibrillation in the epicardial border zone of hearts with healed myocardial infarction. Circulation 103 (2001) 1465-1472
8. Janse M.J., and Wit A.L. Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction. Physiol Rev 69 (1989) 1049-1169
9. Peters N.S., Coromilas J., Severs N.J., et al. Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia. Circulation 95 (1997) 988-996
10. Li L., Nikolski V., Wallick D.W., et al. Mechanisms of enhanced shock-induced arrhythmogenesis in the rabbit heart with healed myocardial infarction. Am J Physiol Heart Circ Physiol 289 (2005) H1054-H1068
11. McLachlan C.S., and McGuire M.A. Characterization and incidence of inducible monomorphic ventricular tachycardia in a postinfarction rabbit model. J Electrocardiol 40 (2007) 89-93
12. Jiang H., Lu Z., Yu Y., et al. Effects of metoprolol on sympathetic remodeling and electrical remodeling at infarcted border zone after myocardial infarction in rabbits. Cardiology 108 (2007) 176-182
13. Panfilov A.V. Is heart size a factor in ventricular fibrillation?. Or how close are rabbit and human hearts?. Heart Rhythm 3 (2006) 862-864
14. Qu F., Ripplinger C.M., Nikolski V.P., et al. Three-dimensional panoramic imaging of cardiac arrhythmias in rabbit heart. J Biomed Opt 12 (2007) 044019
15. Kay M.W., Amison P.M., and Rogers J.M. Three-dimensional surface reconstruction and panoramic optical mapping of large hearts. IEEE Trans Biomed Eng 51 (2004) 1219-1229
16. Pumir A., and Krinsky V. Unpinning of a rotating wave in cardiac muscle by an electric field. J Theoret Biol 199 (1999) 311-319
17. Takagi S., Pumir A., Pazó D., et al. Unpinning and removal of a rotating wave in cardiac muscle. Phys Rev Lett (2004)
18. Ripplinger C.M., Krinsky V.I., Nikolski V.P., et al. Mechanisms of unpinning and termination of ventricular tachycardia. Am J Physiol Heart Circ Physiol 291 (2006) H184-H192
19. Fedorov V.V., Schuessler R.B., Lall S., et al. Low voltage defibrillation of sustained ventricular tachycardia in infarcted canine hearts. Heart Rhythm 4 (2007) S171
20. Coromilas J., Saltman A.E., Waldecker B., et al. Electrophysiological effects of flecainide on anisotropic conduction and reentry in infarcted canine hearts. Circulation 91 (1995) 2245-2263
21. Efimov I.R., Cheng Y.N., Biermann M., et al. Transmembrane voltage changes produced by real and virtual electrodes during monophasic defibrillation shock delivered by an implantable electrode. J Cardiovasc Electrophysiol 8 (1997) 1031-1045
22. Fedorov V.V., Lozinsky I.T., Sosunov E.A., et al. Application of blebbistatin as an excitation-contraction uncoupler for electrophysiologic study of rat and rabbit hearts. Heart Rhythm 4 (2007) 619-626
23. Bray M.A., Lin S.F., and Wikswo J. Three-dimensional visualization of phase singularities on the isolated rabbit heart. J Cardiovasc Electrophysiol 13 (2002) 1311
24. Bayly P.V., KenKnight B.H., Rogers J.M., et al. Estimation of conduction velocity vector fields from epicardial mapping data. IEEE Trans Biomed Eng 45 (1998) 563-571
25. Hucker W.J., McCain M.L., Laughner J.I., et al. Connexin 43 expression delineates two discrete pathways in the human atrioventricular junction. Anat Rec (Hoboken) 291 (2007) 204-215
26. Fast V.G., Rohr S., Gillis A.M., et al. Activation of cardiac tissue by extracellular electrical shocks: formation of "secondary sources" at intercellular clefts in monolayers of cultured myocytes. Circ Res 82 (1998) 375-385
27. Trayanova N., Skouibine K., and Aguel F. The role of cardiac tissue structure in defibrillation. Chaos 8 (1998) 221-233
28. Cheng Y., Nikolski V., and Efimov I.R. Virtual electrode induced transmural and midmyocardial scroll-waves during internal defibrillation shocks. Circulation 102 (2000) 340-341
29. Ashihara T., Constantino J., and Trayanova N.A. Tunnel propagation of postshock activations as a hypothesis for fibrillation induction and isoelectric window. Circ Res 102 6 (2008) 737-745
30. Cheng Y., Li L., Nikolski V., et al. Shock-induced arrhythmogenesis is enhanced by 2,3-butanedione monoxime compared with cytochalasin D. Am J Physiol 286 (2004) H310-H318
31. Dhein S., Muller A., Gerwin R., et al. Comparative study on the proarrhythmic effects of some antiarrhythmic agents. Circulation 87 (1993) 617-630
32. Ranger S., and Nattel S. Determinants and mechanisms of flecainide-induced promotion of ventricular tachycardia in anesthetized dogs. Circulation 92 (1995) 1300-1311
33. Jalife J., Berenfeld O., and Mansour M. Mother rotors and fibrillatory conduction:a mechanism of atrial fibrillation. Cardiovasc Res 54 (2002) 204-216
34. Wathen M.S., DeGroot P.J., Sweeney M.O., et al. Prospective randomized multicenter trial of empirical antitachycardia pacing versus shocks for spontaneous rapid ventricular tachycardia in patients with implantable cardioverter-defibrillators: Pacing Fast Ventricular Tachycardia Reduces Shock Therapies (PainFREE Rx II) trial results. Circulation 110 (2004) 2591-2596
35. Kouakam C., Lauwerier B., Klug D., et al. Effect of elevated heart rate preceding the onset of ventricular tachycardia on antitachycardia pacing effectiveness in patients with implantable cardioverter defibrillators. Am J Cardiol 92 (2003) 26-32