Oxidative stress mediates apoptotic effects of ascorbate and dehydroascorbate in human Myelodysplasia cells in vitro

Toxicology in Vitro

Volumn 27, Issue 5, 2013, Pages 1542-1549

  Gonçalves, Ana Cristina ^a,b   Alves, Vera ^a   Silva, Teresa ^a   Carvalho, Cristina ^b,c   Oliveira, Catarina Resende de ^a,b   Sarmento Ribeiro, Ana Bela ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Anti cancer therapy; Apoptosis; Ascorbate; Dehydroascorbate; Myelodysplastic Syndrome; Oxidative stress

Indexed keywords

ASCORBIC ACID; CYTARABINE; CYTOCHROME C; DEHYDROASCORBIC ACID; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TRYPAN BLUE;

APOPTOSIS; ARTICLE; CELL LINE; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROSCOPY; MITOCHONDRIAL MEMBRANE POTENTIAL; MYELODYSPLASTIC SYNDROME; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; TREATMENT RESPONSE;

APOPTOSIS; ASCORBIC ACID; BCL-2-ASSOCIATED X PROTEIN; CATALASE; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CYTOCHROMES C; DEHYDROASCORBIC ACID; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MYELODYSPLASTIC SYNDROMES; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84877012656     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2013.03.009     Document Type: Article

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