메뉴 건너뛰기




Volumn 17, Issue 4, 2013, Pages 543-549

Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and promoter methylation in cervical oncogenic lesions and cancer

Author keywords

Cervical cancer; DNA methylation; HrHPV; MTHFR polymorphism

Indexed keywords

METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MTHFR PROTEIN, HUMAN;

EID: 84877011655     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12032     Document Type: Article
Times cited : (21)

References (40)
  • 1
    • 0017681169 scopus 로고
    • Human papilloma viruses and their possible role in squamous cell carcinomas
    • zur Hausen H. Human papilloma viruses and their possible role in squamous cell carcinomas. Curr Top Microbiol Immunol. 1977; 78: 1-30.
    • (1977) Curr Top Microbiol Immunol , vol.78 , pp. 1-30
    • Zur Hausen, H.1
  • 2
    • 0141887322 scopus 로고    scopus 로고
    • HPV infection and number of lifetime sexual partners are strong predictors for natural regression of CIN 2 and 3
    • Chan K, Monk BJ, Brewer C, et al. HPV infection and number of lifetime sexual partners are strong predictors for natural regression of CIN 2 and 3. Br J Cancer. 2003; 89: 1062-6.
    • (2003) Br J Cancer , vol.89 , pp. 1062-1066
    • Chan, K.1    Monk, B.J.2    Brewer, C.3
  • 3
    • 0032968974 scopus 로고    scopus 로고
    • Sexual behaviour and papillomavirus exposure in cervical intraepithelial neoplasia: a population-based case-control study
    • Kjellberg L, Wang Z, Wiklund F, et al. Sexual behaviour and papillomavirus exposure in cervical intraepithelial neoplasia: a population-based case-control study. J Gen Virol. 1999; 80: 391-8.
    • (1999) J Gen Virol , vol.80 , pp. 391-398
    • Kjellberg, L.1    Wang, Z.2    Wiklund, F.3
  • 4
    • 0024542352 scopus 로고
    • Cigarette smoking and exposure to passive smoke are risk factors for cervical cancer
    • Slattery ML, Robison LM, Schuman KL, et al. Cigarette smoking and exposure to passive smoke are risk factors for cervical cancer. JAMA. 1989; 261: 1593-8.
    • (1989) JAMA , vol.261 , pp. 1593-1598
    • Slattery, M.L.1    Robison, L.M.2    Schuman, K.L.3
  • 5
    • 0025257322 scopus 로고
    • Oral contraceptive use and risk of invasive cervical cancer
    • Brinton LA, Reeves WC, Brenes MM, et al. Oral contraceptive use and risk of invasive cervical cancer. Int J Epidemiol. 1990; 19: 4-11.
    • (1990) Int J Epidemiol , vol.19 , pp. 4-11
    • Brinton, L.A.1    Reeves, W.C.2    Brenes, M.M.3
  • 7
    • 0031656598 scopus 로고    scopus 로고
    • Hypomethylation in cervical tissue: is there a correlation with folate status?
    • Fowler BM, Giuliano AR, Piyathilake C, et al. Hypomethylation in cervical tissue: is there a correlation with folate status? Cancer Epidemiol Biomarkers Prev. 1998; 7: 901-6.
    • (1998) Cancer Epidemiol Biomarkers Prev , vol.7 , pp. 901-906
    • Fowler, B.M.1    Giuliano, A.R.2    Piyathilake, C.3
  • 8
    • 0032906750 scopus 로고    scopus 로고
    • Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement
    • Bailey LB, Gregory JF 3rd. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement. J Nutr. 1999; 29: 919-22.
    • (1999) J Nutr , vol.29 , pp. 919-922
    • Bailey, L.B.1    Gregory, III.J.F.2
  • 9
    • 0037117501 scopus 로고    scopus 로고
    • A common mutation in the 5,10 - methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status
    • Friso S, Choi SW, Girelli D, et al. A common mutation in the 5, 10 - methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acad Sci USA. 2002; 99: 5606-11.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5606-5611
    • Friso, S.1    Choi, S.W.2    Girelli, D.3
  • 10
    • 84890552372 scopus 로고    scopus 로고
    • MTHFR polymorphism and the risk of prostate cancer: a meta-analysis of case-control studies, prostate cancer and prostatic diseases
    • Li XL, Xu JH. MTHFR polymorphism and the risk of prostate cancer: a meta-analysis of case-control studies, prostate cancer and prostatic diseases. Neuromolecular Med. 2012; 14: 84-90.
    • (2012) Neuromolecular Med , vol.14 , pp. 84-90
    • Li, X.L.1    Xu, J.H.2
  • 11
    • 35748970501 scopus 로고    scopus 로고
    • MTHFR polymorphisms' influence on outcome and toxicity in acute lymphoblastic leukemia patients
    • Chiusolo P, Reddiconto G, Farina G, et al. MTHFR polymorphisms' influence on outcome and toxicity in acute lymphoblastic leukemia patients. Leuk Res. 2007; 31: 1669-74.
    • (2007) Leuk Res , vol.31 , pp. 1669-1674
    • Chiusolo, P.1    Reddiconto, G.2    Farina, G.3
  • 12
    • 33750942294 scopus 로고    scopus 로고
    • Association of MTHFR gene polymorphisms with breast cancer survival
    • Martin DN, Boersma BJ, Howe TM, et al. Association of MTHFR gene polymorphisms with breast cancer survival. BMC Cancer. 2006; 6: 257-67.
    • (2006) BMC Cancer , vol.6 , pp. 257-267
    • Martin, D.N.1    Boersma, B.J.2    Howe, T.M.3
  • 13
    • 77951238604 scopus 로고    scopus 로고
    • A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis
    • Palomino-Morales R, Gonzalez-Juanatey C, Vazquez-Rodriguez TR, et al. A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis. Arthritis Res Ther. 2010; 12: R71.
    • (2010) Arthritis Res Ther , vol.12
    • Palomino-Morales, R.1    Gonzalez-Juanatey, C.2    Vazquez-Rodriguez, T.R.3
  • 14
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HG, Milos R, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet. 1995; 10: 11-3.
    • (1995) Nat Genet , vol.10 , pp. 11-13
    • Frosst, P.1    Blom, H.G.2    Milos, R.3
  • 15
    • 34249977815 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and the risk of primary hepatocellular carcinoma (HCC) in a Chinese population
    • Mu LN, Cao W, Zhang ZF, et al. Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and the risk of primary hepatocellular carcinoma (HCC) in a Chinese population. Cancer Causes Control. 2007; 18: 665-75.
    • (2007) Cancer Causes Control , vol.18 , pp. 665-675
    • Mu, L.N.1    Cao, W.2    Zhang, Z.F.3
  • 16
    • 27744471516 scopus 로고    scopus 로고
    • Meta-analysis of MTHFR 677C→ T polymorphism and coronary heart disease: does totality of evidence support causal role for homocysteine and preventive potential of folate?
    • Lewis SJ, Ebrahim S, Smith GD. Meta-analysis of MTHFR 677C→ T polymorphism and coronary heart disease: does totality of evidence support causal role for homocysteine and preventive potential of folate? BMJ. 2005; 331: 1053.
    • (2005) BMJ , vol.331 , pp. 1053
    • Lewis, S.J.1    Ebrahim, S.2    Smith, G.D.3
  • 17
    • 0033695123 scopus 로고    scopus 로고
    • Association of the C677T polymorphism in the MTHFR gene with breast and/or ovarian cancer risk in Jewish women
    • Gershoni-Baruch R, Dagan E, Israeli D, et al. Association of the C677T polymorphism in the MTHFR gene with breast and/or ovarian cancer risk in Jewish women. Eur J Cancer. 2000; 36: 2313-6.
    • (2000) Eur J Cancer , vol.36 , pp. 2313-2316
    • Gershoni-Baruch, R.1    Dagan, E.2    Israeli, D.3
  • 18
    • 0035957379 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia
    • Wiemels JL, Smith RN, Taylor GM, et al. Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia. Proc Natl Acad Sci USA. 2001; 98: 4004-9.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4004-4009
    • Wiemels, J.L.1    Smith, R.N.2    Taylor, G.M.3
  • 19
    • 26444545116 scopus 로고    scopus 로고
    • Polymorphisms of methylenetetra-hydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population
    • Schnakenberg E, Mehles A, Cario G, et al. Polymorphisms of methylenetetra-hydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population. BMC Med Genet. 2005; 6: 23-7.
    • (2005) BMC Med Genet , vol.6 , pp. 23-27
    • Schnakenberg, E.1    Mehles, A.2    Cario, G.3
  • 20
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer. 2004; 4: 143-53.
    • (2004) Nat Rev Cancer , vol.4 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 21
    • 0033569641 scopus 로고    scopus 로고
    • Epigenetics: regulation through repression
    • Wolffe AP, Matzke MA. Epigenetics: regulation through repression. Science. 1999; 286: 481-6.
    • (1999) Science , vol.286 , pp. 481-486
    • Wolffe, A.P.1    Matzke, M.A.2
  • 22
    • 34547779010 scopus 로고    scopus 로고
    • Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors
    • Costa VL, Henrique R, Ribeiro FR, et al. Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors. BMC Cancer. 2007; 7: 133.
    • (2007) BMC Cancer , vol.7 , pp. 133
    • Costa, V.L.1    Henrique, R.2    Ribeiro, F.R.3
  • 23
    • 68949208601 scopus 로고    scopus 로고
    • MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: the role of epigenetics in male infertility
    • Khazamipour N, Noruzinia M, Fatehmanesh P, et al. MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: the role of epigenetics in male infertility. Hum Reprod. 2009; 24: 2361-4.
    • (2009) Hum Reprod , vol.24 , pp. 2361-2364
    • Khazamipour, N.1    Noruzinia, M.2    Fatehmanesh, P.3
  • 24
    • 79952122331 scopus 로고    scopus 로고
    • Integrated analysis of gene expression, CpG Island methylation, and gene copy number in breast cancercells by deep sequencing
    • Sun Z, Asmann YW, Kalari KR, et al. Integrated analysis of gene expression, CpG Island methylation, and gene copy number in breast cancercells by deep sequencing. PLoS ONE. 2011; 6: e17490.
    • (2011) PLoS ONE , vol.6
    • Sun, Z.1    Asmann, Y.W.2    Kalari, K.R.3
  • 25
    • 84867531510 scopus 로고    scopus 로고
    • Association between gene expression of metabolizing enzymes and esophageal squamous cell carcinomas in China
    • Liu R, Yin L, Pu Y. Association between gene expression of metabolizing enzymes and esophageal squamous cell carcinomas in China. Genet Test Mol Biomarkers. 2012; 16: 1211-7.
    • (2012) Genet Test Mol Biomarkers , vol.16 , pp. 1211-1217
    • Liu, R.1    Yin, L.2    Pu, Y.3
  • 26
    • 3042825295 scopus 로고    scopus 로고
    • Quantitative multiplex methylation-specific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer
    • Fackler MJ, McVeigh M, Mehrotra J, et al. Quantitative multiplex methylation-specific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer. Cancer Res. 2004; 64: 4442-52.
    • (2004) Cancer Res , vol.64 , pp. 4442-4452
    • Fackler, M.J.1    McVeigh, M.2    Mehrotra, J.3
  • 27
    • 34548497655 scopus 로고    scopus 로고
    • Human papillomavirus and cervical cancer
    • Schiffman M, Castle PE, Jeronimo J, et al. Human papillomavirus and cervical cancer. Lancet. 2007; 370: 890-907.
    • (2007) Lancet , vol.370 , pp. 890-907
    • Schiffman, M.1    Castle, P.E.2    Jeronimo, J.3
  • 28
    • 0029855024 scopus 로고    scopus 로고
    • A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer
    • Chen J, Giovannucci E, Kelsey K, et al. A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer. Cancer Res. 1996; 56: 4862-4.
    • (1996) Cancer Res , vol.56 , pp. 4862-4864
    • Chen, J.1    Giovannucci, E.2    Kelsey, K.3
  • 29
    • 0033768152 scopus 로고    scopus 로고
    • Methyl group metabolism gene polymorphisms and susceptibility to prostatic carcinoma
    • Kimura F, Franke KH, Steinhoff C, et al. Methyl group metabolism gene polymorphisms and susceptibility to prostatic carcinoma. Prostate. 2000; 45: 225-31.
    • (2000) Prostate , vol.45 , pp. 225-231
    • Kimura, F.1    Franke, K.H.2    Steinhoff, C.3
  • 30
    • 0035922101 scopus 로고    scopus 로고
    • Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population: a case-control study
    • Shen H, Xu Y, Zheng Y, et al. Polymorphisms of 5, 10-methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population: a case-control study. Int J Cancer. 2001; 95: 332-6.
    • (2001) Int J Cancer , vol.95 , pp. 332-336
    • Shen, H.1    Xu, Y.2    Zheng, Y.3
  • 31
    • 84871316230 scopus 로고    scopus 로고
    • Cervical cancer with polymorphism in MTHFR C677T gene: a systematic review and meta-analysis
    • Xu XJ, Zou LW, Wang DB. Cervical cancer with polymorphism in MTHFR C677T gene: a systematic review and meta-analysis. Mol Biol Rep. 2013; 40: 255-62.
    • (2013) Mol Biol Rep , vol.40 , pp. 255-262
    • Xu, X.J.1    Zou, L.W.2    Wang, D.B.3
  • 32
    • 84867024975 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to cervical cancer and cervical intraepithelial neoplasia: a meta-analysis
    • Luo YL, Ye P, Zhang QH, et al. Methylenetetrahydrofolate reductase C677T polymorphism and susceptibility to cervical cancer and cervical intraepithelial neoplasia: a meta-analysis. PLoS ONE. 2012; 7: e46272.
    • (2012) PLoS ONE , vol.7
    • Luo, Y.L.1    Ye, P.2    Zhang, Q.H.3
  • 33
    • 84867236301 scopus 로고    scopus 로고
    • The association between MTHFR 677C>Tpolymorphism and cervical cancer: evidence from a meta-analysis
    • Mei Q, Zhou D, Gao J, et al. The association between MTHFR 677C>Tpolymorphism and cervical cancer: evidence from a meta-analysis. BMC Cancer. 2012; 12: 467.
    • (2012) BMC Cancer , vol.12 , pp. 467
    • Mei, Q.1    Zhou, D.2    Gao, J.3
  • 34
    • 34948905809 scopus 로고    scopus 로고
    • MTHFR polymorphisms as prognostic factors in sporadic colorectal cancer
    • Osian G, Procopciuc L, Vlad L. MTHFR polymorphisms as prognostic factors in sporadic colorectal cancer. Gastrointestin Liver Dis. 2007; 16: 251-6.
    • (2007) Gastrointestin Liver Dis , vol.16 , pp. 251-256
    • Osian, G.1    Procopciuc, L.2    Vlad, L.3
  • 35
    • 0035660287 scopus 로고    scopus 로고
    • Association of methylenetetrahydrofolate reductase polymorphism C677T and dietary folate with the risk of cervical dysplasia
    • Goodman MT, McDuffie K, Hernandez B, et al. Association of methylenetetrahydrofolate reductase polymorphism C677T and dietary folate with the risk of cervical dysplasia. Cancer Epidemiol Biomarkers Prev. 2001; 10: 1275-80.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 1275-1280
    • Goodman, M.T.1    McDuffie, K.2    Hernandez, B.3
  • 36
    • 0344642945 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism C677T is not associated to the risk of cervical dysplasia
    • Lambropoulos AF, Agorastos T, Foka ZJ, et al. Methylenetetrahydrofolate reductase polymorphism C677T is not associated to the risk of cervical dysplasia. Cancer Lett. 2003; 191: 187-91.
    • (2003) Cancer Lett , vol.191 , pp. 187-191
    • Lambropoulos, A.F.1    Agorastos, T.2    Foka, Z.J.3
  • 37
    • 74249109712 scopus 로고    scopus 로고
    • Distribution of p53, GST, and MTHFR polymorphisms and risk of cervical intraepithelial lesions in Sicily
    • Agodi A, Barchitta M, Cipresso R, et al. Distribution of p53, GST, and MTHFR polymorphisms and risk of cervical intraepithelial lesions in Sicily. Int J Gynecol Cancer. 2010; 20: 141-6.
    • (2010) Int J Gynecol Cancer , vol.20 , pp. 141-146
    • Agodi, A.1    Barchitta, M.2    Cipresso, R.3
  • 38
    • 10044281662 scopus 로고    scopus 로고
    • Polymorphism in folate- and methionine-metabolizing enzyme and aberrant CpG island hypermethylation in uterine cervical cancer
    • Kang S, Kim JW, Kang GH, et al. Polymorphism in folate- and methionine-metabolizing enzyme and aberrant CpG island hypermethylation in uterine cervical cancer. Gynecol Oncol. 2005; 96: 173-80.
    • (2005) Gynecol Oncol , vol.96 , pp. 173-180
    • Kang, S.1    Kim, J.W.2    Kang, G.H.3
  • 39
    • 43949142803 scopus 로고    scopus 로고
    • Identification of novel DNA methylation markers in cervical cancer
    • Lai HC, Lin YW, Huang TH, et al. Identification of novel DNA methylation markers in cervical cancer. Int J Cancer. 2008; 123: 161-7.
    • (2008) Int J Cancer , vol.123 , pp. 161-167
    • Lai, H.C.1    Lin, Y.W.2    Huang, T.H.3
  • 40
    • 35648962315 scopus 로고    scopus 로고
    • Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis
    • Calvisi DF, Simile MM, Ladu S, et al. Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis. Int J Cancer. 2007; 121: 2410-20.
    • (2007) Int J Cancer , vol.121 , pp. 2410-2420
    • Calvisi, D.F.1    Simile, M.M.2    Ladu, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.