Comparative proteomics study on liver mitochondria of primary biliary cirrhosis mouse model

BMC Gastroenterology

Volumn 13, Issue 1, 2013, Pages

  Song, Guang ^a,b   Hu, Chaojun ^a   Zhu, Huishan ^c   Li, Xi ^a   Zhao, Liying ^c   Zhou, Renfang ^a   Zhang, Xuan ^a   Zhang, Fengchun ^a   Wu, Lin ^b   Li, Yongzhe ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b Chinese Academy of Sciences   (China)

^c Beijing Protein Innovation Co Ltd   (China)

Author keywords

iTRAQ; Molecular pathogenesis; Primary biliary cirrhosis; Proteomics

Indexed keywords

2,4 DIENOYL COENZYME A REDUCTASE (NADPH); 3 HYDROXYACYL COENZYME A DEHYDROGENASE; CARNITINE PALMITOYLTRANSFERASE I; ENOYL COENZYME A HYDRATASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; LIPID METABOLISM; LIVER MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PATHOGENESIS; PRIMARY BILIARY CIRRHOSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEOMICS; STEROIDOGENESIS; UPREGULATION; VALIDATION PROCESS; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; DOWN-REGULATION; LIPID METABOLISM; LIVER; LIVER CIRRHOSIS, BILIARY; MICE; MICE, INBRED C57BL; MITOCHONDRIA; OXIDATION-REDUCTION; POLY I-C; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; UP-REGULATION;

EID: 84876979613     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/1471-230X-13-64     Document Type: Article

References (35)

1. Poupon R. Primary biliary cirrhosis: A 2010 update. J Hepatol 2010, 52(5):745-758. 10.1016/j.jhep.2009.11.027, 20347176.
2. Selmi C, Bowlus CL, Gershwin ME, Coppel RL. Primary biliary cirrhosis. Lancet 2011, 377(9777):1600-1609. 10.1016/S0140-6736(10)61965-4, 21529926.
3. Gershwin ME, Selmi C, Worman HJ, Gold EB, Watnik M, Utts J, Lindor KD, Kaplan MM, Vierling JM. Risk factors and comorbidities in primary biliary cirrhosis: a controlled interview-based study of 1032 patients. Hepatology 2005, 42(5):1194-1202. 10.1002/hep.20907, 3150736, 16250040.
4. Invernizzi P, Pasini S, Selmi C, Gershwin ME, Podda M. Female predominance and X chromosome defects in autoimmune diseases. J Autoimmun 2009, 33(1):12-16. 10.1016/j.jaut.2009.03.005, 19356902.
5. Lindor KD, Gershwin ME, Poupon R, Kaplan M, Bergasa NV, Heathcote EJ. Primary biliary cirrhosis. Hepatology 2009, 50(1):291-308. 10.1002/hep.22906, 19554543.
6. Djafarzadeh S, Vuda M, Takala J, Ochs M, Jakob SM. Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes. Mitochondrion 2011, 11(1):83-88. 10.1016/j.mito.2010.07.010, 20691286.
7. Perez MJ, Briz O. Bile-acid-induced cell injury and protection. World J Gastroenterol 2009, 15(14):1677-1689. 10.3748/wjg.15.1677, 2668773, 19360911.
8. Simula MP, De Re V. Hepatitis C virus-induced oxidative stress and mitochondrial dysfunction: a focus on recent advances in proteomics. Proteomics Clin Appl 2010, 4(10-11):782-793.
9. Ibdah JA, Morris EM, Rector RS, Thyfault JP. Mitochondria and Redox Signaling in Steatohepatitis. Antioxid Redox Signal 2010, 15(2):485-504.
10. Labbe G, Pessayre D, Fromenty B. Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies. Fundam Clin Pharmacol 2008, 22(4):335-353. 10.1111/j.1472-8206.2008.00608.x, 18705745.
11. Okada C, Akbar SM, Horiike N, Onji M. Early development of primary biliary cirrhosis in female C57BL/6 mice because of poly I:C administration. Liver Int 2005, 25(3):595-603. 10.1111/j.1478-3231.2005.01043.x, 15910497.
12. Jiang T, Han Z, Chen S, Wu C, Tang Y, Qian C, Chen Y, Zhou Y, Zhu Y, Gu M. Resistance to activation-induced cell death and elevated FLIP(L) expression of CD4+ T cells in a polyI:C-induced primary biliary cirrhosis mouse model. Clin Exp Med 2009, 9(4):269-276. 10.1007/s10238-009-0052-2, 19418018.
13. Wang D, Zhang H, Liang J, Gu Z, Ma X, Huang J, Lin J, Hou Y, Lu L, Sun L. Effect of allogeneic bone marrow-derived mesenchymal stem cells transplantation in a polyI:C-induced primary biliary cirrhosis mouse model. Clin Exp Med 2011, 11(1):25-32. 10.1007/s10238-010-0105-6, 20661620.
14. Zhang W, Fei Y, Gao J, Liu B, Zhang F. The Role of CXCR3 in the Induction of Primary Biliary Cirrhosis. Clin Dev Immunol 2011, 2011:564062. 3102447, 21647407.
15. Shi L, Wang Y, Tu S, Li X, Sun M, Srivastava S, Xu N, Bhatnagar A, Liu S. The responses of mitochondrial proteome in rat liver to the consumption of moderate ethanol: the possible roles of aldo-keto reductases. J Proteome Res 2008, 7(8):3137-3145. 10.1021/pr700853j, 18597514.
16. Keller A, Nesvizhskii AI, Kolker E, Aebersold R. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem 2002, 74(20):5383-5392. 10.1021/ac025747h, 12403597.
17. Nesvizhskii AI, Keller A, Kolker E, Aebersold R. A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem 2003, 75(17):4646-4658. 10.1021/ac0341261, 14632076.
18. Fan NJ, Gao CF, Wang CS, Lv JJ, Zhao G, Sheng XH, Wang XL, Li DH, Liu QY, Yin J. Discovery and verification of gelsolin as a potential biomarker of colorectal adenocarcinoma in the Chinese population: Examining differential protein expression using an iTRAQ labelling-based proteomics approach. Can J Gastroenterol 2012, 26(1):41-47. 3275404, 22288069.
19. Li L, Gong H, Yu H, Liu X, Liu Q, Yan G, Zhang Y, Lu H, Zou Y, Yang P. Knockdown of nucleosome assembly protein 1-like 1 promotes dimethyl sulfoxide-induced differentiation of P19CL6 cells into cardiomyocytes. J Cell Biochem 2012, 113(12):3788-3796. 10.1002/jcb.24254, 22807403.
20. Guo Y, Singleton PA, Rowshan A, Gucek M, Cole RN, Graham DR, Van Eyk JE, Garcia JG. Quantitative proteomics analysis of human endothelial cell membrane rafts: evidence of MARCKS and MRP regulation in the sphingosine 1-phosphate-induced barrier enhancement. Mol Cell Proteomics 2007, 6(4):689-696. 10.1074/mcp.M600398-MCP200, 17210631.
21. Datta A, Park JE, Li X, Zhang H, Ho ZS, Heese K, Lim SK, Tam JP, Sze SK. Phenotyping of an in vitro model of ischemic penumbra by iTRAQ-based shotgun quantitative proteomics. J Proteome Res 2010, 9(1):472-484. 10.1021/pr900829h, 19916522.
22. Unwin RD, Griffiths JR, Whetton AD. Simultaneous analysis of relative protein expression levels across multiple samples using iTRAQ isobaric tags with 2D nano LC-MS/MS. Nat Protoc 2010, 5(9):1574-1582. 10.1038/nprot.2010.123, 21085123.
23. Lengqvist J, Uhlen K, Lehtio J. iTRAQ compatibility of peptide immobilized pH gradient isoelectric focusing. Proteomics 2007, 7(11):1746-1752. 10.1002/pmic.200600782, 17476709.
24. Mao TK, Lian ZX, Selmi C, Ichiki Y, Ashwood P, Ansari AA, Coppel RL, Shimoda S, Ishibashi H, Gershwin ME. Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis. Hepatology 2005, 42(4):802-808. 10.1002/hep.20859, 16175622.
25. Nakamura M, Funami K, Komori A, Yokoyama T, Aiba Y, Araki A, Takii Y, Ito M, Matsuyama M, Koyabu M. Increased expression of Toll-like receptor 3 in intrahepatic biliary epithelial cells at sites of ductular reaction in diseased livers. Hepatol Int 2008, 2(2):222-230. 10.1007/s12072-008-9055-4, 2716858, 19669308.
26. Shimoda S, Harada K, Niiro H, Shirabe K, Taketomi A, Maehara Y, Tsuneyama K, Nakanuma Y, Leung P, Ansari AA. Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis. Hepatology 2011, 53(4):1270-1281. 10.1002/hep.24194, 3077894, 21400555.
27. Zhang H, Zhao C, Li X, Zhu Y, Gan CS, Wang Y, Ravasi T, Qian PY, Wong SC, Sze SK. Study of monocyte membrane proteome perturbation during lipopolysaccharide-induced tolerance using iTRAQ-based quantitative proteomic approach. Proteomics 2010, 10(15):2780-2789. 10.1002/pmic.201000066, 20486119.
28. Peters A. The energy request of inflammation. Endocrinology 2006, 147(10):4550-4552. 10.1210/en.2006-0815, 16980440.
29. Ambade A, Mandrekar P. Oxidative stress and inflammation: essential partners in alcoholic liver disease. Int J Hepatol 2012, 2012:853175. 3303590, 22500241.
30. Wei Y, Clark SE, Thyfault JP, Uptergrove GM, Li W, Whaley-Connell AT, Ferrario CM, Sowers JR, Ibdah JA. Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic Ren2 rats. Am J Pathol 2009, 174(4):1329-1337. 10.2353/ajpath.2009.080697, 2671364, 19246643.
31. Mantena SK, King AL, Andringa KK, Eccleston HB, Bailey SM. Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases. Free Radic Biol Med 2008, 44(7):1259-1272. 10.1016/j.freeradbiomed.2007.12.029, 2323912, 18242193.
32. Grasfeder LL, Gaillard S, Hammes SR, Ilkayeva O, Newgard CB, Hochberg RB, Dwyer MA, Chang CY, McDonnell DP. Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha. Mol Endocrinol 2009, 23(8):1171-1182. 10.1210/me.2009-0024, 2718748, 19389810.
33. Anakk S, Watanabe M, Ochsner SA, McKenna NJ, Finegold MJ, Moore DD. Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis. J Clin Invest 2011, 121(1):86-95. 10.1172/JCI42846, 3007143, 21123943.
34. Ota Y, Eto TA, Tanaka S, Sueta H, Shiotsuki H, Maeda Y, Une M, Chijiiwa K. Assay method for mitochondrial sterol 27-hydroxylase with 7alpha-hydroxy-4-cholesten-3-one as a substrate in the rat liver. J Lipid Res 2003, 44(12):2400-2405. 10.1194/jlr.D200045-JLR200, 12951370.
35. Matsuzaki Y, Bouscarel B, Ikegami T, Honda A, Doy M, Ceryak S, Fukushima S, Yoshida S, Shoda J, Tanaka N. Selective inhibition of CYP27A1 and of chenodeoxycholic acid synthesis in cholestatic hamster liver. Biochim Biophys Acta 2002, 1588(2):139-148. 10.1016/S0925-4439(02)00157-6, 12385778.