Astrocytes as Neural Stem Cells in the Adult Brain

Journal of Stem Cells

Volumn 7, Issue 3, 2012, Pages 181-188

  Gonzalez Perez, Oscar ^a,b   Quiñones Hinojosa, Alfredo ^c  

^a UNIVERSIDAD DE COLIMA   (Mexico)

^b UNIVERSITY OF GUADALAJARA   (Mexico)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; NESTIN; PLATELET DERIVED GROWTH FACTOR; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; ASTROCYTE; BRAIN; CELL PROLIFERATION; CELL RENEWAL; HUMAN; INTERNEURON; NEURAL STEM CELL; OLFACTORY BULB; OLIGODENDROGLIA; PROTEIN EXPRESSION; SUBVENTRICULAR ZONE; WHITE MATTER;

ANIMALS; ASTROCYTES; BRAIN; CELL DIFFERENTIATION; HUMANS; NEURAL STEM CELLS;

MAMMALIA;

EID: 84876952593     PISSN: 15568539     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Altman J. (1962) Are new neurons formed in the brains of adult mammals? Science 135:1127-1128.
2. Altman J., Gopal DD (1965) Post-natal origin of microneurones in the rat brain. Nature 207:953-956.
3. Altman J., Das G. D. (1967) Autoradiographic and Histological Studies of Postnatal Neurogenesis. I. A Longitudinal Investigation of the Kinetics, Migration and Transformation of Cells Incorporating Tritiated Thymidine in Neonate Rats, with Special Reference to Postnatal Neurogenesis in Some Brain Regions. J. Comp Neurol. 126:337-390.
4. Alvarez-Buylla A., Garcia-Verdugo J. M. (2002) Neurogenesis in adult subventricular zone. J. Neurosci 22:629-634.
5. Alvarez-Buylla A., Seri B, Doetsch F (2002) Identification of neural stem cells in the adult vertebrate brain. Brain Res Bull 57:751-758.
6. Bull N. D, Bartlett P. F. (2005) The adult mouse hippocampal progenitor is neurogenic but not a stem cell. J Neurosci 25:10815-10821.
7. Capela A., Temple S. (2002) LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. Neuron 35:865-875.
8. Craig C. G., Tropepe V., Morshead C. M., Reynolds B. A., Weiss S., Van der Kooy D. (1996) In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain. J. Neurosci. 16:2649-2658.
9. Chiasson B. J., Tropepe V., Morshead C. M., Van der Kooy D. (1999) Adult Mammalian Forebrain Ependymal and Subependymal Cells Demonstrate Proliferative Potential, but only Subependymal Cells Have Neural Stem Cell Characteristics. J. Neurosci. 19:4462-4471.
10. Doetsch F. (2003) The glial identity of neural stem cells. Nat Neurosci 6:1127-1134.
11. Doetsch F., Garcia-Verdugo J. M., Alvarez-Buylla A. (1997) Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J. Neurosci. 17:5046-5061.
12. Doetsch F., Garcia-Verdugo J. M., Alvarez-Buylla A. (1999a) Regeneration of a germinal layer in the adult mammalian brain. Proc. Natl. Acad Sci. USA 96:11619-11624.
13. Doetsch F., Caille I., Lim D. A., García-Verdugo J. M., Alvarez-Buylla A. (1999b) Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult mammalian Brain. Cell 97:1-20.
14. Doetsch F., Caille I., Lim D. A., Garcia-Verdugo J. M., Alvarez-Buylla A. (1999c) Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97:703-716.
15. Doetsch F., Petreanu L., Caille I., Garcia-Verdugo J. M., Alvarez-Buylla A. (2002) EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron 36:1021-1034.
16. Garcia A. D., Doan N. B., Imura T., Bush T. G., Sofroniew M. V. (2004) GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nat Neurosci 7:1233-1241.
17. Gheusi G., Cremer H., McLean H., Chazal G., Vincent J. D., Lledo P. M (2000) Importance of newly generated neurons in the adult olfactory bulb for odor discrimination. Proc Natl Acad Sci USA 97:1823-1828.
18. Goldman S. A., Nottebohm F. (1983) Neuronal production, migration, and differentiation in a vocal control nucleus of the adult female canary brain. Proc Natl Acad Sci USA 80:2390-2394.
19. Gonzalez-Perez O. (2010) Hydrocephaly does not modify neuroblast chain migration in the subventricular zone (SVZ). Gac. Med. Mex 148:130-136.
20. Gonzalez-Perez O., Quinones-Hinojosa A. (2010) Dose-dependent effect of EGF on migration and differentiation of adult subventricular zone astrocytes. Glia 58:975-983.
21. Gonzalez-Perez O., Alvarez-Buylla A. (2011) Oligodendrogenesis in the subventricular zone and the role of epidermal growth factor. Brain Res Rev 67:147-156.
22. Gonzalez-Perez O., Romero-Rodriguez R., Soriano-Navarro M., Garcia-Verdugo J. M., Alvarez-Buylla A. (2009) Epidermal Growth Factor Induces the Progeny of Subventricular Zone Type B Cells to Migrate and Differentiate into Oligodendrocytes. Stem Cells 27:2032-2043.
23. Gritti A., Cova L., Parati E. A., Galli R., Vescovi A. L. (1995) Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS. Neurosci Lett 185:151-154.
24. Gritti A., Frolichsthal-Schoeller P., Galli R, Parati E. A., Cova L., Pagano S. F., Bjornson C. R. R., Vescovi A. L. (1999) Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem celllike population from the subventricular region of the adult mouse forebrain. J. Neurosci 19:3287-3297.
25. Holland E. C., Varmus H. E. (1998) Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice. Proc. Natl. Acad. Sci. USA 95:1218-1223.
26. Imura T., Kornblum H I., Sofroniew M. V. (2003) The Predominant Neural Stem Cell Isolated from Postnatal and Adult Forebrain But Not Early Embryonic Forebrain Expresses GFAP. J. Neurosci 23:2824-2832.
27. Jackson E. L., Garcia-Verdugo J. M., Gil-Perotin S., Roy M., Quinones-Hinojosa A., VandenBerg S., Alvarez-Buylla A. (2006) PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling. Neuron 51:187-199.
28. Jagasia R., Song H., Gage F. H., Lie D. C. (2006) New regulators in adult neurogenesis and their potential role for repair. Trends Mol Med 12:400-405.
29. Kaplan M. S., Hinds J. W. (1977) Neurogenesis in the adult rat: Electron microscopic analysis of light radioautographs. Science 197:1092-1094.
30. Kokovay E., Goderie S., Wang Y., Lotz S., Lin G., Sun Y., Roysam B., Shen Q., Temple S. (2010) Adult S. V. Z. Lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling. Cell Stem Cell 7:163-173.
31. Laywell E. D., Rakic P., Kukekov V. G., Holland E. C., Steindler D. A. (2000) Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain. Proc. Natl. Acad. Sci. USA 97:13883-13888.
32. Leventhal C., Rafii S., Rafii D., Shahar A., Goldman S. (1999) Endothelial Trophic Support of Neuronal Production and Recruitment from the Adult Mammalian Subependyma. Mol. Cell Neurosci 13:450-464.
33. Lim D. A., Alvarez-Buylla A. (1999) Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis. Proc Natl Acad Sci USA 96. 96:7526-7531.
34. Lois C., Alvarez-Buylla A. (1993) Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia. Proc. Natl. Acad. Sci. USA 90:2074-2077.
35. Lois C., Alvarez-Buylla A. (1994a) Long-distance neuronal migration in the adult mammalian brain. Science 264:1145-1148.
36. Lois C., Alvarez-Buylla A. (1994b) Long-distance neuronal migration in the adult mammalian brain. Science 264:1145-1148.
37. Lois C., Garcia-Verdugo J. M., Alvarez-Buylla A. (1996) Chain migration of neuronal precursors. Science 271:978-981.
38. Luskin M. B. (1993) Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron 11:173-189.
39. Menn B., Garcia-Verdugo J M., Yaschine C., Gonzalez-Perez O., Rowitch D., Alvarez-Buylla A. (2006) Origin of oligodendrocytes in the subventricular zone of the adult brain. J. Neurosci. 26:7907-7918.
40. Mercier F., Kitasako J. T., Hatton G. I. (2002) Anatomy of the brain neurogenic zones revisited: fractones and the fibroblast/macrophage network. J. Comp. Neurol 451:170-188.
41. Merkle F. T., Mirzadeh Z., Alvarez-Buylla A. (2007) Mosaic organization of neural stem cells in the adult brain. Science 317:381-384.
42. Merkle F. T., Tramontin A. D., Garcia-Verdugo J. M., Alvarez-Buylla A. (2004) Radial glia give rise to adult neural stem cells in the subventricular zone. Proc. Natl. Acad. Sci. USA 101:17528-17532.
43. Mirzadeh Z., Merkle F. T., Soriano-Navarro M., Garcia-Verdugo J. M., Alvarez-Buylla A. (2008) Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell 3:265-278.
44. Morshead C. M., Garcia A. D., Sofroniew M. V., van Der Kooy D. (2003) The ablation of glial fibrillary acidic protein-positive cells from the adult central nervous system results in the loss of forebrain neural stem cells but not retinal stem cells. Eur. J. Neurosci 18:76-84.
45. Morshead C. M., Reynolds B. A., Craig C. G., McBurney M. W., Staines W. A., Morassutti D., Weiss S., Van der Kooy D. (1994) Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells. Neuron 13:1071-1082.
46. 3H]thymidine autoradiographic and bromodeoxyuridine immunocytochemical study. Dev Brain Res 93:49-61.
47. Quinones-Hinojosa A., Sanai N., Soriano-Navarro M., Gonzalez-Perez O., Mirzadeh Z., Gil-Perotin S., Romero-Rodriguez R., Berger M. S., Garcia-Verdugo J. M., Alvarez-Buylla A. (2006) Cellular composition and cytoarchitecture of the adult human subventricular zone: a niche of neural stem cells. J Comp Neurol 494:415-434.
48. Reynolds B., Weiss S. (1992) Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255:1707-1710.
49. Reznikov K. Y. (1991) Cell proliferation and cytogenesis in the mouse hippocampus. Adv. Anat. Embryol. Cell Biol 122:1-74.
50. Rietze R. L., Valcanis H., Brooker G. F., Thomas T., Voss A. K., Bartlett P. F. (2001) Purification of a pluripotent neural stem cell from the adult mouse brain. Nature 412:736-739.
51. Sanai N., Tramontin A. D., Quinones-Hinojosa A., Barbaro N. M., Gupta N., Kunwar S., Lawton M. T., McDermott M. W., Parsa A. T., Manuel-Garcia Verdugo J., Berger M. S., Alvarez-Buylla A. (2004) Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration. Nature 427:740-744.
52. Sawamoto K., Wichterle H., Gonzalez-Perez O., Cholfin J. A., Yamada M., Spassky N., Murcia N. S., Garcia-Verdugo J. M., Marin O., Rubenstein J. L., Tessier-Lavigne M., Okano H., Alvarez-Buylla A. (2006) New neurons follow the flow of cerebrospinal fluid in the adult brain. Science 311:629-632.
53. Seaberg R. M., van der Kooy D. (2002) Adult rodent neurogenic regions: the ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors. J. Neurosci. 22:1784-1793.
54. Seri B., Garcia-Verdugo J. M., McEwen B. S., Alvarez-Buylla A. (2001) Astrocytes give rise to new neurons in the adult mammalian hippocampus. J. Neurosci. 21:7153-7160.
55. Shen Q., Wang Y., Kokovay E., Lin G., Chuang S. M., Goderie S. K., Roysam B., Temple S. (2008) Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions. Cell Stem Cell 3:289-300.
56. Song H. J., Stevens C. F., Gage F. H. (2002) Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons. Nat Neurosci 5:438-445.
57. Spassky N., Merkle F. T., Flames N., Tramontin A. D., Garcia-Verdugo J. M., Alvarez-Buylla A. (2005) Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis. J. Neurosci 25:10-18.
58. Tavazoie M., Van der Veken L., Silva-Vargas V., Louissaint M., Colonna L., Zaidi B., Garcia-Verdugo J. M., Doetsch F. (2008) A specialized vascular niche for adult neural stem cells. Cell Stem Cell 3:279-288.
59. Vescovi A. L., Reynolds B. A., Fraser D. D., Weiss S. (1993) bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron 11: 951-966.
60. Weiss S., Reynolds B. A., Vescovi A. L., Morshead C., Craig C. G., Van der Kooy D. (1996) Is there a neural stem cell in the mammalian forebrain? Trends Neurosci. 19:387-393.
61. Wichterle H., Garcia-Verdugo J. M., Alvarez-Buylla A. (1997) Direct evidence for homotypic, glia-independent neuronal migration. Neuron 18:779-791.