The ablation of glial fibrillary acidic protein-positive cells from the adult central nervous system results in the loss of forebrain neural stem cells but not retinal stem cells

European Journal of Neuroscience

Volumn 18, Issue 1, 2003, Pages 76-84

  Morshead, Cindi M ^a   Garcia, A Denize ^b   Sofroniew, Michael V ^b   Van Der Kooy, Derek ^c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Astrocyte; Mouse; Neurosphere; Subependyma

Indexed keywords

GANCICLOVIR; GLIAL FIBRILLARY ACIDIC PROTEIN; GREEN FLUORESCENT PROTEIN; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EPENDYMA; FEMALE; FOREBRAIN; HERPES SIMPLEX VIRUS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NERVE CELL; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA; STEM CELL; TRANSGENIC MOUSE;

ANIMALS; ANTIVIRAL AGENTS; CELL SEPARATION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CEREBRAL VENTRICLES; COCULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; GANCICLOVIR; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; NEURONS; PROSENCEPHALON; RETINA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIMPLEXVIRUS; STEM CELLS;

EID: 0043169430     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02727.x     Document Type: Article

References (41)

1. Altman, J. (1969) Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb. J. Comp. Neurol., 137, 433-458.
2. Alvarez-Buylla, A., Garcia-Verdugo, J.M. & Tramontin, A.D. (2001) A unified hypothesis on the lineage of neural stem cells. Nature Rev. Neurosci., 2, 287-293.
3. Alvarez-Buylla, A., Theleen, M. & Nottebohm, F. (1990) Proliferation 'hot spots' in the adult avian ventricular zone reveal radial cell division. Neuron, 5, 101-109.
4. Borelli, E., Heyman, R.A., Arias, C., Sawchenko, P.E. & Evans, R.M. (1989) Transgenic mice with inducible dwarfism. Nature, 339, 538-541.
5. Bush, T.G., Puvanachandra, N., Home, C.H., Polito, A., Ostenfeld, T., Svendsen, C.N., Mucke, L., Johnson, M.H. & Sofroniew, M.V. (1999) Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice. Neuron, 23, 297-308.
6. Bush, T.G., Savidge, T.C., Freeman, T.C., Cox, H.J., Campbell, E.A., Mucke, L., Johnson, M.H. & Sofroniew, M.V. (1998) Fulminant jejuno-ileitis following ablation of enteric glia in adult transgenic mice. Cell, 93, 189-201.
7. Chiasson, B.J., Tropepe, V., Morshead, C.M. & van der Kooy, D. (1999) Adult mammalian forebrain ependymal and subependymal cells demonstrate proliferative potential, but only subependymal cells have neural stem cell characteristics. J. Neurosci., 19, 4462-4471.
8. Doetsch, F., Garcia-Verdugo, J.M. & Alvarez-Buylla, A. (1997) Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J. Neurosci., 17, 5046-5061.
9. Doetsch, F., Caille, I., Lim, D.A., Garcia-Verdugo, J.M. & Alvarez-Buylla, A. (1999a) Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell, 97, 703-716.
10. Doetsch, F., Garcia-Verdugo, J.M. & Alvarez-Buylla, A. (1999b) Regeneration of a germinal layer in the adult mammalian brain. Proc. Natl. Acad. Sci. USA, 96, 11619-11624.
11. Doetsch, F., Petreanu, L., Caille, I., Garcia-Verdugo, J.-M. & Alvarez-Buylla, A. (2002) EGF converts transit-amplifying neurogenic precursors in the adult brain into pluripotent stem cells. Neuron, 36, 1021-1034.
12. Frank, K.B., Chiou, J.-F. & Cheng, Y.-C. (1984) Interaction of herpes simplex virus-induced DNA polymerase with 9-(1,3-dihydroxy-2-propoxymethyl) gyanine triphosphate. J. Biol. Chem., 259, 1566-1569.
13. Fuchs, E. & Segre, J.A. (2000) Stem cells: a new lease on life. Cell, 100, 143-155.
14. Gaiano, N., Nye, J.S. & Fishell, G. (2000) Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron, 26, 395-404.
15. Gritti, A., Bonfanti, L., Doetsch, F., Caille, I., Alvarez-Buylla, A., Lim, D.A., Galli, R., Verdugo, J.M., Herrera, D.G. & Vescovi, A.L. (2002) Multipotent neural stem cells reside into the rostral extension and olfactory bulbs of adult rodents. J. Neurosci., 22, 437-445.
16. Gritti, A., Parati, E.A., Cova, L., Frolichsthal, P., Galli, R., Wanke, E., Faravelli, L., Morassutti, D.J., Roisen, F., Nickell, D.D. & Vescovi, A.L. (1996) Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. J. Neurosci., 16, 1091-1100.
17. Hadjantonakis, A.-K., Gertsenstein, M., Ikawa, M., Okabe, M. & Nagy, A. (1998) Generating green fluorescent mice by germline transmission of green fluorescent ES cells. Mech. Dev., 76, 79-90.
18. Heins, N., Malatesta, P., Cecconi, F., Nakafuku, M., Tucker, K.L., Hack, M.H., Chapouton, P., Barde, Y.-A. & Gotz, M. (2002) Glial cells generate neurons: the role of the transcription factor Pax6. Nature Nearosci., 5, 308-315.
19. Heyman, R.A., Borrelli, E., Lesley, J., Anderson, D., Richman, D.D. & Baird, S.M. (1989) Thymidine kinase obliteration: creation of transgenic mice with controlled immune deficiency. Proc. Natl. Acad. Sci. USA, 86, 2698-2702.
20. Laywell, E.D., Raki, P., Kukekov, V.G., Holland, E.C. & Steindler, D.A. (2000) Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain. Proc. Natl. Acad. Sci. USA, 97, 13883-13888.
21. Lim, D.A. & Alvarez-Buylla, A. (1999) Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis. Proc. Natl. Acad. Sci. USA, 96, 7526-7531.
22. Malatesta, P., Hartfuss, E. & Gotz, M. (2000) Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage. Development, 127, 5253-5263.
23. Marino, S., Vooijs, M., van der Gulden, H., Jonkers, J. & Berns, A. (2000) Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev., 8, 994-1004.
24. Misson, J.P., Edwards, M.A., Yamamoto, M. & Caviness, V.R. Jr (1988) Mitotic cycling of radial glial cells of the fetal routine cerebral wall: a combined autoradiographic and immunohistochemical study. Dev. Brain Res., 38, 183-190.
25. Morshead, C.M., Benveniste, P., Iscove, N.N. & van der Kooy, D. (2002) Hematopoietic competence is a rare property of neural stem cells and may depend on genetic and epigenetic alterations. Nature Med., 8, 268-273.
26. Morshead, C.M., Craig, C.G. & van der Kooy, D. (1998) In vivo clonal analyses reveal the properties of endogenous neural stem cell proliferation in the adult mammalian forebrain. Development, 125, 2251-2261.
27. Morshead, C.M., Reynolds, B.A., Craig, C.G., McBurney, M.W., Staines, W.A., Morassutti, D., Weiss, S. & van der Kooy, D. (1994) Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells. Neuron, 13, 1071-1082.
28. Morshead, C.M. & van der Kooy, D. (2001) A new 'spin' on neural stem cells? Curr. Opin. Neurobiol., 11, 59-65.
29. Noctor, S.C., Flint, A.C., Weissman, T.A., Wong, W.S., Clinton, B.K. & Kriegstein, A.R. (2002) Dividing precursor cells in the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia. J. Neurosci., 22, 3161-3173.
30. Pekney, M., Leveen, P., Pekna, M., Eliasson, C., Berthold, C.H., Westermark, B. & Belsholtz, C. (1995) Mice lacking glial fibrillary acidic protein display astrocytes devoid of intermediate filaments but develop and reproduce normally. EMBO J., 14, 1590-1598.
31. Pixley, S.K.R., & De Vellis, J. (1984) Transition between immature radial glia and mature astrocytes studied with a monoclonal antibody to vimentin. Dev. Brain Res., 15, 201-209.
32. Reynolds, B.A. & Weiss, S. (1992) Generation of neurons and astrocytes from isolated cells of the adult mammalian nervous system. Science, 255, 1707-1710.
33. Reynolds, B.A. & Weiss, S. (1996) Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev. Biol., 175, 1-13.
34. Rietze, R.L., Valcanis, H., Brooker, G.F., Thomas, T., Voss, A.K. & Bartlett, P.F. (2001) Purification of a pluripotent neural stem cell from the adult mouse brain. Nature, 412, 736-739.
35. 3 injection. J. Comp. Neurol., 116, 325-348.
36. Song, H., Stevens, C.F. & Gage, F.H. (2002) Astroglia induce neurogenesis from adult neural stem cells. Nature, 417, 39-44.
37. Sturrock, R.R. & Smart, I.H.M. (1980) A morphological study of the mouse subependymal layer from embryonic life to old age. J. Anat., 130, 391-415.
38. Tropepe, V., Coles, B.L.K., Chiasson, B.J., Horsford, D.J., Elia, A.J., McInnes, R.R. & van der Kooy, D. (2000) Retinal stem cells in the adult mammalian eye. Science, 287, 2032-2036.
39. Tropepe, V., Craig, C.G., Morshead, C.M. & van der Kooy, D. (1997) Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma. J. Neurosci., 17, 7850-7859.
40. Tropepe, V., Sibilia, M., Ciruna, B.G., Rossant, J., Wagner, E.F. & van der Kooy, D. (1999) Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Dev. Biol., 208, 166-188.
41. Voigt, T. (1989) Development of glial cells in the cerebral wall of ferrets: direct tracing of their transformation from radial glia into astrocytes. J. Comp. Neurol., 289, 74-88.