Caffeic acid phenethyl ester suppresses proliferation and survival of TW2.6 human oral cancer cells via inhibition of akt signaling

International Journal of Molecular Sciences

Volumn 14, Issue 5, 2013, Pages 8801-8817

  Kuo, Ying Yu ^a   Lin, Hui Ping ^a   Huo, Chieh ^a,b   Su, Liang Cheng ^a   Yang, Jonathan ^a   Hsiao, Ping Hsuan ^a,c   Chiang, Hung Che ^a   Chung, Chi Jung ^d   Wang, Horng Dar ^c   Chang, Jang Yang ^a   Chen, Ya Wen ^a   Chuu, Chih Pin ^a,d,e  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^c NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

5 fluorouracil; Akt; Akt1; Akt2; Caffeic acid phenethyl ester; Cell cycle; Cell proliferation; Cyclin D1; FOXO1; FOXO3a; NF B; Oral cancer; P27; Phospho Akt Ser473; Phospho Akt Thr 308; Phospho FOXO1 Thr24; Phospho FoxO3a Thr32; Phospho NF B Ser536; Phospho Rb Ser807 811; Rb; Skp2; TW2.6

Indexed keywords

CAFFEIC ACID PHENETHYL ESTER; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; FLUOROURACIL; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHOPROTEIN; PROTEIN AKT1; PROTEIN AKT3; PROTEIN KINASE B; PROTEIN KINASE B BETA; RETINOBLASTOMA PROTEIN; S PHASE KINASE ASSOCIATED PROTEIN 2; SERINE; THREONINE; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; CAFFEIC ACID DERIVATIVE; PHENETHYL ALCOHOL;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL POPULATION; CELL PROLIFERATION; CELL STRAIN; CELL STRAIN TW2.6; CELL SURVIVAL; COLONY FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUTH SQUAMOUS CELL CARCINOMA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; BIOLOGICAL MODEL; CELL CYCLE; DRUG EFFECTS; DRUG SCREENING; ENZYMOLOGY; METABOLISM; MOUTH TUMOR; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

APIS MELLIFERA;

APOPTOSIS; CAFFEIC ACIDS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DRUG SYNERGISM; FLUOROURACIL; HUMANS; MODELS, BIOLOGICAL; MOUTH NEOPLASMS; NF-KAPPA B; PHENYLETHYL ALCOHOL; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TUMOR STEM CELL ASSAY;

EID: 84876948881     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14058801     Document Type: Article

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