-
1
-
-
79751499788
-
Disorders of bone remodeling
-
Feng X, McDonald JM (2011) Disorders of bone remodeling. Annu Rev Pathol 6:121-145.
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 121-145
-
-
Feng, X.1
McDonald, J.M.2
-
2
-
-
26444506000
-
Transforming growth factor-beta1 to the bone
-
Janssens K, ten Dijke P, Janssens S, Van Hul W (2005) Transforming growth factor-beta1 to the bone. Endocr Rev 26(6):743-774.
-
(2005)
Endocr Rev
, vol.26
, Issue.6
, pp. 743-774
-
-
Janssens, K.1
Ten Dijke, P.2
Janssens, S.3
Van Hul, W.4
-
3
-
-
0346024110
-
TGF-beta Signaling in Human Skeletal and Patterning Disorders
-
DOI 10.1002/bdrc.10023
-
Serra R, Chang C (2003) TGF-beta signaling in human skeletal and patterning disorders. Birth Defects Res C Embryo Today 69(4):333-351. (Pubitemid 38076457)
-
(2003)
Birth Defects Research Part C - Embryo Today: Reviews
, vol.69
, Issue.4
, pp. 333-351
-
-
Serra, R.1
Chang, C.2
-
4
-
-
78349238109
-
Inhibition of TGF-β signaling by 1D11 antibody treatment increases bone mass and quality in vivo
-
Edwards JR, et al. (2010) Inhibition of TGF-β signaling by 1D11 antibody treatment increases bone mass and quality in vivo. J Bone Miner Res 25(11):2419-2426.
-
(2010)
J Bone Miner Res
, vol.25
, Issue.11
, pp. 2419-2426
-
-
Edwards, J.R.1
-
5
-
-
65349134769
-
Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone
-
Mohammad KS, et al. (2009) Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone. PLoS One 4(4):e5275.
-
(2009)
PLoS One
, vol.4
, Issue.4
-
-
Mohammad, K.S.1
-
6
-
-
0037148521
-
Bone abnormalities in latent TGF-beta binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-beta bioavailability
-
DOI 10.1083/jcb.200111080
-
Dabovic B, et al. (2002) Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability. J Cell Biol 156(2):227-232. (Pubitemid 34839904)
-
(2002)
Journal of Cell Biology
, vol.156
, Issue.2
, pp. 227-232
-
-
Dabovic, B.1
Chen, Y.2
Colarossi, C.3
Obata, H.4
Zambuto, L.5
Perle, M.A.6
Rifkin, D.B.7
-
7
-
-
0029671373
-
Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype
-
Erlebacher A, Derynck R (1996) Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype. J Cell Biol 132(1-2):195-210.
-
(1996)
J Cell Biol
, vol.132
, Issue.1-2
, pp. 195-210
-
-
Erlebacher, A.1
Derynck, R.2
-
8
-
-
0032710016
-
Inhibition of TGF-beta receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass
-
Filvaroff E, et al. (1999) Inhibition of TGF-beta receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass. Development 126(19):4267-4279. (Pubitemid 29509342)
-
(1999)
Development
, vol.126
, Issue.19
, pp. 4267-4279
-
-
Filvaroff, E.1
Erlebacher, A.2
Ye, J.-Q.3
Gitelman, S.E.4
Lotz, J.5
Heillman, M.6
Derynck, R.7
-
9
-
-
0033763317
-
Mutations in the gene encoding the latency-associated peptide of TGF-beta 1 cause Camurati-Engelmann disease
-
Janssens K, et al. (2000) Mutations in the gene encoding the latency-associated peptide of TGF-beta 1 cause Camurati-Engelmann disease. Nat Genet 26(3):273-275.
-
(2000)
Nat Genet
, vol.26
, Issue.3
, pp. 273-275
-
-
Janssens, K.1
-
10
-
-
67650506105
-
TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
-
Tang Y, et al. (2009) TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat Med 15(7):757-765.
-
(2009)
Nat Med
, vol.15
, Issue.7
, pp. 757-765
-
-
Tang, Y.1
-
11
-
-
0037439630
-
Making sense of latent TGFbeta activation
-
DOI 10.1242/jcs.00229
-
Annes JP, Munger JS, Rifkin DB (2003) Making sense of latent TGFbeta activation. J Cell Sci 116(Pt 2):217-224. (Pubitemid 36163863)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.2
, pp. 217-224
-
-
Annes, J.P.1
Munger, J.S.2
Rifkin, D.B.3
-
12
-
-
0028906190
-
Processing of transforming growth factor beta 1 precursor by human furin convertase
-
Dubois CM, Laprise MH, Blanchette F, Gentry LE, Leduc R (1995) Processing of transforming growth factor beta 1 precursor by human furin convertase. J Biol Chem 270(18):10618-10624.
-
(1995)
J Biol Chem
, vol.270
, Issue.18
, pp. 10618-10624
-
-
Dubois, C.M.1
Laprise, M.H.2
Blanchette, F.3
Gentry, L.E.4
Leduc, R.5
-
13
-
-
0026701960
-
Retention of the transforming growth factor-beta 1 precursor in the Golgi complex in a latent endoglycosidase H-sensitive form
-
Miyazono K, Thyberg J, Heldin CH (1992) Retention of the transforming growth factor-beta 1 precursor in the Golgi complex in a latent endoglycosidase H-sensitive form. J Biol Chem 267(8):5668-5675.
-
(1992)
J Biol Chem
, vol.267
, Issue.8
, pp. 5668-5675
-
-
Miyazono, K.1
Thyberg, J.2
Heldin, C.H.3
-
14
-
-
50449084307
-
ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation
-
Le Goff C, et al. (2008) ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation. Nat Genet 40(9):1119-1123.
-
(2008)
Nat Genet
, vol.40
, Issue.9
, pp. 1119-1123
-
-
Le Goff, C.1
-
15
-
-
0026480854
-
Identification of a cysteine-rich receptor for fibroblast growth factors
-
Burrus LW, Zuber ME, Lueddecke BA, Olwin BB (1992) Identification of a cysteine-rich receptor for fibroblast growth factors. Mol Cell Biol 12(12):5600-5609.
-
(1992)
Mol Cell Biol
, vol.12
, Issue.12
, pp. 5600-5609
-
-
Burrus, L.W.1
Zuber, M.E.2
Lueddecke, B.A.3
Olwin, B.B.4
-
16
-
-
0028876875
-
The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor
-
Steegmaier M, et al. (1995) The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor. Nature 373(6515):615-620.
-
(1995)
Nature
, vol.373
, Issue.6515
, pp. 615-620
-
-
Steegmaier, M.1
-
17
-
-
0030943989
-
Latent transforming growth factor-beta complex in Chinese hamster ovary cells contains the multifunctional cysteine-rich fibroblast growth factor receptor, also termed E-selectin-ligand or MG-160
-
Olofsson A, et al. (1997) Latent transforming growth factor-beta complex in Chinese hamster ovary cells contains the multifunctional cysteine-rich fibroblast growth factor receptor, also termed E-selectin-ligand or MG-160. Biochem J 324(Pt 2):427-434. (Pubitemid 27267984)
-
(1997)
Biochemical Journal
, vol.324
, Issue.2
, pp. 427-434
-
-
Olofsson, A.1
Hellman, U.2
Ten, D.P.3
Grimsby, S.4
Ichijo, H.5
Moren, A.6
Miyazono, K.7
Heldin, C.-H.8
-
18
-
-
0029083332
-
MG160, a membrane protein of the Golgi apparatus which is homologous to a fibroblast growth factor receptor and to a ligand for E-selectin, is found only in the Golgi apparatus and appears early in chicken embryo development
-
Stieber A, Mourelatos Z, Chen YJ, Le Douarin N, Gonatas NK (1995) MG160, a membrane protein of the Golgi apparatus which is homologous to a fibroblast growth factor receptor and to a ligand for E-selectin, is found only in the Golgi apparatus and appears early in chicken embryo development. Exp Cell Res 219(2):562-570.
-
(1995)
Exp Cell Res
, vol.219
, Issue.2
, pp. 562-570
-
-
Stieber, A.1
Mourelatos, Z.2
Chen, Y.J.3
Le Douarin, N.4
Gonatas, N.K.5
-
19
-
-
77954990272
-
E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta
-
Yang T, et al. (2010) E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta. J Clin Invest 120(7):2474- 2485.
-
(2010)
J Clin Invest
, vol.120
, Issue.7
, pp. 2474-2485
-
-
Yang, T.1
-
20
-
-
0037673945
-
Osteoclast differentiation and activation
-
DOI 10.1038/nature01658
-
Boyle WJ, Simonet WS, Lacey DL (2003) Osteoclast differentiation and activation. Nature 423(6937):337-342. (Pubitemid 40852708)
-
(2003)
Nature
, vol.423
, Issue.6937
, pp. 337-342
-
-
Boyle, W.J.1
Simonet, W.S.2
Lacey, D.L.3
-
21
-
-
0025998393
-
Latent forms of transforming growth factor-beta (TGFbeta) derived from bone cultures: Identification of a naturally occurring 100-kDa complex with similarity to recombinant latent TGFbeta
-
Bonewald LF, et al. (1991) Latent forms of transforming growth factor-beta (TGF beta) derived from bone cultures: Identification of a naturally occurring 100-kDa complex with similarity to recombinant latent TGF beta. Mol Endocrinol 5(6):741-751. (Pubitemid 21923727)
-
(1991)
Molecular Endocrinology
, vol.5
, Issue.6
, pp. 741-751
-
-
Bonewald, L.F.1
Wakefield, L.2
Oreffo, R.O.C.3
Escobedo, A.4
Twardzik, D.R.5
Mundy, G.R.6
-
22
-
-
0028302076
-
Characterization and autoregulation of latent transforming growth factor beta (TGF beta) complexes in osteoblast-like cell lines. Production of a latent complex lacking the latent TGF beta-binding protein
-
Dallas SL, et al. (1994) Characterization and autoregulation of latent transforming growth factor beta (TGF beta) complexes in osteoblast-like cell lines. Production of a latent complex lacking the latent TGF beta-binding protein. J Biol Chem 269(9):6815-6821.
-
(1994)
J Biol Chem
, vol.269
, Issue.9
, pp. 6815-6821
-
-
Dallas, S.L.1
-
23
-
-
0029025627
-
Processing of pro-PTHRP by the prohormone convertase, furin: Effect on biological activity
-
Liu B, Goltzman D, Rabbani SA (1995) Processing of pro-PTHRP by the prohormone convertase, furin: Effect on biological activity. Am J Physiol 268(5 Pt 1):E832-E838.
-
(1995)
Am J Physiol
, vol.268
, Issue.5 PART 1
-
-
Liu, B.1
Goltzman, D.2
Rabbani, S.A.3
-
24
-
-
0038481179
-
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis
-
Siegfried G, et al. (2003) The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. J Clin Invest 111(11):1723-1732. (Pubitemid 38057753)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.11
, pp. 1723-1732
-
-
Siegfried, G.1
Basak, A.2
Cromlish, J.A.3
Benjannet, S.4
Marcinkiewicz, J.5
Chretien, M.6
Seidah, N.G.7
Khatib, A.-M.8
-
25
-
-
30044443293
-
TGF-beta regulates the mechanical properties and composition of bone matrix
-
DOI 10.1073/pnas.0507417102
-
Balooch G, et al. (2005) TGF-beta regulates the mechanical properties and composition of bone matrix. Proc Natl Acad Sci USA 102(52):18813-18818. (Pubitemid 43049527)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.52
, pp. 18813-18818
-
-
Balooch, G.1
Balooch, M.2
Nalla, R.K.3
Schilling, S.4
Filvaroff, E.H.5
Marshall, G.W.6
Marshall, S.J.7
Ritchie, R.O.8
Derynck, R.9
Alliston, T.10
-
26
-
-
33644751775
-
Emilin1 links TGF-beta maturation to blood pressure homeostasis
-
DOI 10.1016/j.cell.2005.12.035, PII S0092867406001140
-
Zacchigna L, et al. (2006) Emilin1 links TGF-beta maturation to blood pressure homeostasis. Cell 124(5):929-942. (Pubitemid 43344234)
-
(2006)
Cell
, vol.124
, Issue.5
, pp. 929-942
-
-
Zacchigna, L.1
Vecchione, C.2
Notte, A.3
Cordenonsi, M.4
Dupont, S.5
Maretto, S.6
Cifelli, G.7
Ferrari, A.8
Maffei, A.9
Fabbro, C.10
Braghetta, P.11
Marino, G.12
Selvetella, G.13
Aretini, A.14
Colonnese, C.15
Bettarini, U.16
Russo, G.17
Soligo, S.18
Adorno, M.19
Bonaldo, P.20
Volpin, D.21
Piccolo, S.22
Lembo, G.23
Bressan, G.M.24
more..
-
27
-
-
80855128847
-
Anti-transforming growth factor β antibody treatment rescues bone loss and prevents breast cancer metastasis to bone
-
Biswas S, et al. (2011) Anti-transforming growth factor β antibody treatment rescues bone loss and prevents breast cancer metastasis to bone. PLoS One 6(11):e27090.
-
(2011)
PLoS One
, vol.6
, Issue.11
-
-
Biswas, S.1
-
28
-
-
23044448510
-
Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3
-
DOI 10.1038/sj.emboj.7600729
-
Kang JS, Alliston T, Delston R, Derynck R (2005) Repression of Runx2 function by TGFbeta through recruitment of class II histone deacetylases by Smad3. EMBO J 24(14):2543-2555. (Pubitemid 41076311)
-
(2005)
EMBO Journal
, vol.24
, Issue.14
, pp. 2543-2555
-
-
Kang, J.S.1
Alliston, T.2
Delston, R.3
Derynck, R.4
-
29
-
-
50449109286
-
Skeletal overexpression of connective tissue growth factor impairs bone formation and causes osteopenia
-
Smerdel-Ramoya A, Zanotti S, Stadmeyer L, Durant D, Canalis E (2008) Skeletal overexpression of connective tissue growth factor impairs bone formation and causes osteopenia. Endocrinology 149(9):4374-4381.
-
(2008)
Endocrinology
, vol.149
, Issue.9
, pp. 4374-4381
-
-
Smerdel-Ramoya, A.1
Zanotti, S.2
Stadmeyer, L.3
Durant, D.4
Canalis, E.5
-
30
-
-
19944426775
-
Altered endochondral bone development in matrix metalloproteinase 13-deficient mice
-
DOI 10.1242/dev.01461
-
Stickens D, et al. (2004) Altered endochondral bone development in matrix metalloproteinase 13-deficient mice. Development 131(23):5883-5895. (Pubitemid 40123905)
-
(2004)
Development
, vol.131
, Issue.23
, pp. 5883-5895
-
-
Stickens, D.1
Behonick, D.J.2
Ortega, N.3
Heyer, B.4
Hartenstein, B.5
Yu, Y.6
Fosang, A.J.7
Schorpp-Kistner, M.8
Angel, P.9
Werb, Z.10
-
31
-
-
77957195034
-
Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGFbeta stimulation of RANKL production
-
Nistala H, Lee-Arteaga S, Smaldone S, Siciliano G, Ramirez F (2010) Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGFbeta stimulation of RANKL production. J Biol Chem 285(44):34126-34133.
-
(2010)
J Biol Chem
, vol.285
, Issue.44
, pp. 34126-34133
-
-
Nistala, H.1
Lee-Arteaga, S.2
Smaldone, S.3
Siciliano, G.4
Ramirez, F.5
-
32
-
-
24644490177
-
Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34
-
DOI 10.1172/JCI24918
-
Miao D, et al. (2005) Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34. J Clin Invest 115(9):2402-2411. (Pubitemid 41266202)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.9
, pp. 2402-2411
-
-
Miao, D.1
He, B.2
Jiang, Y.3
Kobayashi, T.4
Soroceanu, M.A.5
Zhao, J.6
Su, H.7
Tong, X.8
Amizuka, N.9
Gupta, A.10
Genant, H.K.11
Kronenberg, H.M.12
Goltzman, D.13
Karaplis, A.C.14
-
33
-
-
80051958406
-
A 7-day continuous infusion of PTH or PTHrP suppresses bone formation and uncouples bone turnover
-
Horwitz MJ, et al. (2011) A 7-day continuous infusion of PTH or PTHrP suppresses bone formation and uncouples bone turnover. J Bone Miner Res 26(9):2287-2297.
-
(2011)
J Bone Miner Res
, vol.26
, Issue.9
, pp. 2287-2297
-
-
Horwitz, M.J.1
-
34
-
-
0023879546
-
Identification of transcripts encoding a parathyroid hormone-like peptide in messenger RNAs from a variety of human and animal tumors associated with humoral hypercalcemia of malignancy
-
Ikeda K, et al. (1988) Identification of transcripts encoding a parathyroid hormone-like peptide in messenger RNAs from a variety of human and animal tumors associated with humoral hypercalcemia of malignancy. J Clin Invest 81(6):2010-2014.
-
(1988)
J Clin Invest
, vol.81
, Issue.6
, pp. 2010-2014
-
-
Ikeda, K.1
-
35
-
-
84865553695
-
Assessment of bone mineral status in children with Marfan syndrome
-
Grover M, et al. (2012) Assessment of bone mineral status in children with Marfan syndrome. Am J Med Genet A 158A(9):2221-2224.
-
(2012)
Am J Med Genet a
, vol.158 A
, Issue.9
, pp. 2221-2224
-
-
Grover, M.1
-
36
-
-
0037373277
-
Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome
-
DOI 10.1038/ng1116
-
Neptune ER, et al. (2003) Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome. Nat Genet 33(3):407-411. (Pubitemid 36278859)
-
(2003)
Nature Genetics
, vol.33
, Issue.3
, pp. 407-411
-
-
Neptune, E.R.1
Frischmeyer, P.A.2
Arking, D.E.3
Myers, L.4
Bunton, T.E.5
Gayraud, B.6
Ramirez, F.7
Sakai, L.Y.8
Dietz, H.C.9
|