Genotoxic signature in cord blood cells of newborns exposed in utero to a zidovudine-based antiretroviral combination

Journal of Infectious Diseases

Volumn 208, Issue 2, 2013, Pages 235-243

  André Schmutz, Isabelle ^a   Dal Cortivo, Liliane ^b   Six, Emmanuelle ^a   Kaltenbach, Sophie ^c   Cocchiarella, Fabienne ^m   Le Chenadec, Jerome ^i,j   Cagnard, Nicolas ^f   Cordier, Anne Gael ^k   Benachi, Alexandra ^k   Mandelbrot, Laurent ^g,h,i   Azria, Elie ^e   Bouallag, Naima ^i,j   Luce, Sonia ^a   Ternaux, Brigitte ^b   Reimann, Christian ^a   Revy, Patrick ^a   Radford Weiss, Isabelle ^c   Leschi, Cristina ^c   Recchia, Alessandra ⁿ   Mavilio, Fulvio ^l,m   Cavazzana, Marina ^a,b   Blanche, Stéphane ^d,g   more..

^a IMAGINE INSTITUTE   (France)

^b Département de Biothérapie   (France)

^c Serv d'Hematologie de l'Enfant   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

^e BICHAT HOSPITAL   (France)

^f INSERM   (France)

^g UNIVERSITÉ PARIS DESCARTES   (France)

^h HÔPITAL LOUIS MOURIER   (France)

ⁱ CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

^j UNIVERSITÉ PARIS SACLAY   (France)

^k HÔPITAL ANTOINE BÉCLÈRE   (France)

^l GÉNÉTHON   (France)

^m UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

ⁿ MD Hop Necker Enf Malades ^*  (France)

more..

Author keywords

aneuploidy; genotoxicity; pregnancy; transcriptome; zidovudine

Indexed keywords

ANTIRETROVIRUS AGENT; ATAZANAVIR; DIDANOSINE; LAMIVUDINE; LAMIVUDINE PLUS LOPINAVIR PLUS RITONAVIR PLUS ZIDOVUDINE; LOPINAVIR; UNCLASSIFIED DRUG; ZIDOVUDINE;

ADULT; ANEMIA; ANEUPLOIDY; ARTICLE; BLM GENE; BLOOD CELL; CD34 SELECTION; CELL COMPARTMENTALIZATION; CELL CYCLE; CELL CYCLE REGULATION; CELL GROWTH; CELL PROLIFERATION; CHROMOSOME; COHORT ANALYSIS; CONTROLLED STUDY; CYTOGENETICS; DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; DOWN REGULATION; ERCC4 GENE; FAM175A GENE; FEMALE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENOTOXICITY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; KARYOTYPE; M PHASE CELL CYCLE CHECKPOINT; NEWBORN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; SUPV3L1 GENE; TRANSCRIPTION REGULATION; UMBILICAL CORD BLOOD; UMBILICAL CORD BLOOD CELL; UPREGULATION; WRN GENE;

ANEUPLOIDY; GENOTOXICITY; PREGNANCY; TRANSCRIPTOME; ZIDOVUDINE;

ADULT; ANTI-HIV AGENTS; ANTIGENS, CD34; CELL CYCLE; DNA REPAIR; DRUG COMBINATIONS; FEMALE; FETAL BLOOD; GENE EXPRESSION PROFILING; HEMATOPOIETIC STEM CELLS; HIV INFECTIONS; HUMANS; INFANT, NEWBORN; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; KARYOTYPING; MATERNAL-FETAL EXCHANGE; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PRENATAL EXPOSURE DELAYED EFFECTS; STEM CELLS; TRANSCRIPTOME; YOUNG ADULT; ZIDOVUDINE;

EID: 84876926913     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jit149     Document Type: Article

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