-
1
-
-
79251501315
-
Fibroblast growth factors: From molecular evolution to roles in development, metabolism and disease
-
Itoh N, Ornitz DM. Fibroblast growth factors: From molecular evolution to roles in development, metabolism and disease. J Biochem 2011;149:121-30.
-
(2011)
J Biochem
, vol.149
, pp. 121-30
-
-
Itoh, N.1
Ornitz, D.M.2
-
2
-
-
1642494893
-
The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity
-
Harmer NJ, Pellegrini L, Chirgadze D, Fernandez-Recio J, Blundell TL. The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity. Biochemistry 2004;43:629-40.
-
(2004)
Biochemistry
, vol.43
, pp. 629-40
-
-
Harmer, N.J.1
Pellegrini, L.2
Chirgadze, D.3
Fernandez-Recio, J.4
Blundell, T.L.5
-
3
-
-
58349115748
-
The Klotho gene family as a regulator of endocrine fibroblast growth factors
-
Kurosu H, Kuro OM. The Klotho gene family as a regulator of endocrine fibroblast growth factors. Mol Cell Endocrinol 2009;299:72-8.
-
(2009)
Mol Cell Endocrinol
, vol.299
, pp. 72-8
-
-
Kurosu, H.1
Kuro, O.M.2
-
4
-
-
2542505481
-
Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes
-
Fu L, John LM, Adams SH, Yu XX, Tomlinson E, Renz M, et al. Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes. Endocrinology 2004;145: 2594-603.
-
(2004)
Endocrinology
, vol.145
, pp. 2594-603
-
-
Fu, L.1
John, L.M.2
Adams, S.H.3
Yu, X.X.4
Tomlinson, E.5
Renz, M.6
-
5
-
-
33750698614
-
Identification of a hormonal basis for gallbladder filling
-
Choi M, Moschetta A, Bookout AL, Peng L, Umetani M,Holmstrom SR, et al. Identification of a hormonal basis for gallbladder filling. Nat Med 2006;12:1253-5.
-
(2006)
Nat Med
, vol.12
, pp. 1253-5
-
-
Choi, M.1
Moschetta, A.2
Bookout, A.L.3
Peng, L.4
Umetani, M.5
Holmstrom, S.R.6
-
6
-
-
20444435873
-
FGF-21 as a novel metabolic regulator
-
Kharitonenkov A, Shiyanova TL, Koester A, Ford AM, Micanovic R, Galbreath EJ, et al. FGF-21 as a novel metabolic regulator. J Clin Invest 2005;115:1627-35.
-
(2005)
J Clin Invest
, vol.115
, pp. 1627-35
-
-
Kharitonenkov, A.1
Shiyanova, T.L.2
Koester, A.3
Ford, A.M.4
Micanovic, R.5
Galbreath, E.J.6
-
7
-
-
78650833297
-
Minireview: Fibroblast growth factor 23 in phosphate homeostasis and bone metabolism
-
Hori M, Shimizu Y, Fukumoto S. Minireview: Fibroblast growth factor 23 in phosphate homeostasis and bone metabolism. Endocrinology 2011;152:4-10.
-
(2011)
Endocrinology
, vol.152
, pp. 4-10
-
-
Hori, M.1
Shimizu, Y.2
Fukumoto, S.3
-
8
-
-
0032822672
-
FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4
-
Xie MH, Holcomb I, Deuel B, Dowd P, Huang A, Vagts A, et al. FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4. Cytokine 1999;11:729-35.
-
(1999)
Cytokine
, vol.11
, pp. 729-35
-
-
Xie, M.H.1
Holcomb, I.2
Deuel, B.3
Dowd, P.4
Huang, A.5
Vagts, A.6
-
9
-
-
34848869695
-
Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21
-
Kurosu H, Choi M, Ogawa Y, Dickson AS, Goetz R, Eliseenkova AV, et al. Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. J Biol Chem 2007;282:26687-95.
-
(2007)
J Biol Chem
, vol.282
, pp. 26687-95
-
-
Kurosu, H.1
Choi, M.2
Ogawa, Y.3
Dickson, A.S.4
Goetz, R.5
Eliseenkova, A.V.6
-
10
-
-
35748973876
-
Coreceptor requirements for fibroblast growth factor-19 signaling
-
WuX, Ge H, Gupte J, Weiszmann J, Shimamoto G, Stevens J, et al.Coreceptor requirements for fibroblast growth factor-19 signaling. J Biol Chem 2007;282:29069-72.
-
(2007)
J Biol Chem
, vol.282
, pp. 29069-72
-
-
WuX Ge, H.1
Gupte, J.2
Weiszmann, J.3
Shimamoto, G.4
Stevens, J.5
-
11
-
-
57749105436
-
Cterminal tail of FGF19 determines its specificity toward Klotho coreceptors
-
Wu X, Lemon B, Li X, Gupte J, Weiszmann J, Stevens J, et al. Cterminal tail of FGF19 determines its specificity toward Klotho coreceptors. J Biol Chem 2008;283:33304-9.
-
(2008)
J Biol Chem
, vol.283
, pp. 33304-9
-
-
Wu, X.1
Lemon, B.2
Li, X.3
Gupte, J.4
Weiszmann, J.5
Stevens, J.6
-
12
-
-
0036086285
-
A mouse model of hepatocellular carcinoma: Ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice
-
Nicholes K, Guillet S, Tomlinson E, Hillan K, Wright B, Frantz GD, et al. A mouse model of hepatocellular carcinoma: Ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice. Am J Pathol 2002;160:2295-307.
-
(2002)
Am J Pathol
, vol.160
, pp. 2295-307
-
-
Nicholes, K.1
Guillet, S.2
Tomlinson, E.3
Hillan, K.4
Wright, B.5
Frantz, G.D.6
-
13
-
-
37849029159
-
Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models
-
Desnoyers LR, Pai R, Ferrando RE, Hotzel K, Le T, Ross J, et al. Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models. Oncogene 2008;27:85-97.
-
(2008)
Oncogene
, vol.27
, pp. 85-97
-
-
Desnoyers, L.R.1
Pai, R.2
Ferrando, R.E.3
Hotzel, K.4
Le, T.5
Ross, J.6
-
14
-
-
48549092215
-
Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling
-
Pai R, Dunlap D, Qing J, Mohtashemi I, Hotzel K, French DM. Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling. Cancer Res 2008;68:5086-95.
-
(2008)
Cancer Res
, vol.68
, pp. 5086-95
-
-
Pai, R.1
Dunlap, D.2
Qing, J.3
Mohtashemi, I.4
Hotzel, K.5
French, D.M.6
-
15
-
-
11244283209
-
The role of fibroblast growth factors and their receptors in prostate cancer
-
Kwabi-Addo B, Ozen M, Ittmann M. The role of fibroblast growth factors and their receptors in prostate cancer. Endocr Relat Cancer 2004;11:709-24.
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 709-24
-
-
Kwabi-Addo, B.1
Ozen, M.2
Ittmann, M.3
-
16
-
-
0032954333
-
Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer
-
Giri D, Ropiquet F, Ittmann M. Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer. Clin Cancer Res 1999;5:1063-71.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1063-71
-
-
Giri, D.1
Ropiquet, F.2
Ittmann, M.3
-
17
-
-
36649025928
-
Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition
-
Acevedo VD, Gangula RD, Freeman KW, Li R, Zhang Y, Wang F, et al. Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition. Cancer Cell 2007;12:559-71.
-
(2007)
Cancer Cell
, vol.12
, pp. 559-71
-
-
Acevedo, V.D.1
Gangula, R.D.2
Freeman, K.W.3
Li, R.4
Zhang, Y.5
Wang, F.6
-
18
-
-
4644223140
-
The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression
-
Wang J, Stockton DW, Ittmann M. The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression. Clin Cancer Res 2004;10:6169-78.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6169-78
-
-
Wang, J.1
Stockton, D.W.2
Ittmann, M.3
-
19
-
-
14844307601
-
Evaluation of the fibroblast growth factor system as a potential target for therapy in human prostate cancer
-
Gowardhan B, Douglas DA, Mathers ME, McKie AB, McCracken SR, Robson CN, et al. Evaluation of the fibroblast growth factor system as a potential target for therapy in human prostate cancer. Br J Cancer 2005;92:320-7.
-
(2005)
Br J Cancer
, vol.92
, pp. 320-7
-
-
Gowardhan, B.1
Douglas, D.A.2
Mathers, M.E.3
McKie, A.B.4
McCracken, S.R.5
Robson, C.N.6
-
20
-
-
34548434816
-
Selective over-expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer
-
Sahadevan K, Darby S, Leung HY, Mathers ME, Robson CN, Gnanapragasam VJ. Selective over-expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer. J Pathol 2007;213:82-90.
-
(2007)
J Pathol
, vol.213
, pp. 82-90
-
-
Sahadevan, K.1
Darby, S.2
Leung, H.Y.3
Mathers, M.E.4
Robson, C.N.5
Gnanapragasam, V.J.6
-
21
-
-
76749136307
-
Evidence for distinct alterations in the FGF axis in prostate cancer progression to an aggressive clinical phenotype
-
Murphy T, Darby S, Mathers ME, Gnanapragasam VJ. Evidence for distinct alterations in the FGF axis in prostate cancer progression to an aggressive clinical phenotype. J Pathol 2010;220:452-60.
-
(2010)
J Pathol
, vol.220
, pp. 452-60
-
-
Murphy, T.1
Darby, S.2
Mathers, M.E.3
Gnanapragasam, V.J.4
-
22
-
-
67449156115
-
Global gene expression analysis of reactive stroma in prostate cancer
-
Dakhova O, Ozen M, Creighton CJ, Li R, Ayala G, Rowley D, et al. Global gene expression analysis of reactive stroma in prostate cancer. Clin Cancer Res 2009;15:3979-89.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3979-89
-
-
Dakhova, O.1
Ozen, M.2
Creighton, C.J.3
Li, R.4
Ayala, G.5
Rowley, D.6
-
23
-
-
79960297620
-
FGFR-4 Arg(3) enhances prostate cancer progression via extracellular signalrelated kinase and serum response factor signaling
-
Yu W, Feng S, Dakhova O, Creighton CJ, Cai Y, Wang J, et al. FGFR-4 Arg(3) enhances prostate cancer progression via extracellular signalrelated kinase and serum response factor signaling. Clin Cancer Res 2011;17:4355-66.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4355-66
-
-
Yu, W.1
Feng, S.2
Dakhova, O.3
Creighton, C.J.4
Cai, Y.5
Wang, J.6
-
24
-
-
79951841313
-
Activation of NF-{kappa}B by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4
-
Wang J, Cai Y, Shao LJ, Siddiqui J, Palanisamy N, Li R, et al. Activation of NF-{kappa}B by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4. Cancer Res 2011;71:1325-33.
-
(2011)
Cancer Res
, vol.71
, pp. 1325-33
-
-
Wang, J.1
Cai, Y.2
Shao, L.J.3
Siddiqui, J.4
Palanisamy, N.5
Li, R.6
-
25
-
-
33646429798
-
Gene expression analyses reveal molecular relationships among 20 regions of the human CNS
-
Roth RB, Hevezi P, Lee J, Willhite D, Lechner SM, Foster AC, et al. Gene expression analyses reveal molecular relationships among 20 regions of the human CNS. Neurogenetics 2006;7:67-80.
-
(2006)
Neurogenetics
, vol.7
, pp. 67-80
-
-
Roth, R.B.1
Hevezi, P.2
Lee, J.3
Willhite, D.4
Lechner, S.M.5
Foster, A.C.6
-
26
-
-
33847246805
-
Oncomine 3.0: Genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles
-
Rhodes DR, Kalyana-Sundaram S, Mahavisno V, Varambally R, Yu J, Briggs BB, et al. Oncomine 3.0: Genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia 2007; 9:166-80.
-
(2007)
Neoplasia
, vol.9
, pp. 166-80
-
-
Rhodes, D.R.1
Kalyana-Sundaram, S.2
Mahavisno, V.3
Varambally, R.4
Yu, J.5
Briggs, B.B.6
-
27
-
-
52949088575
-
Fibroblast growth factor-19: Development, analytical characterization and clinical evaluation of a new ELISA test
-
Stejskal D, Karpisek M, Hanulova Z, Stejskal P. Fibroblast growth factor-19: Development, analytical characterization and clinical evaluation of a new ELISA test. Scand J Clin Lab Invest 2008;68: 501-7.
-
(2008)
Scand J Clin Lab Invest
, vol.68
, pp. 501-7
-
-
Stejskal, D.1
Karpisek, M.2
Hanulova, Z.3
Stejskal, P.4
-
28
-
-
33751115468
-
Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man
-
Lundasen T, Galman C, Angelin B, Rudling M. Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man. J Intern Med 2006;260:530-6.
-
(2006)
J Intern Med
, vol.260
, pp. 530-6
-
-
Lundasen, T.1
Galman, C.2
Angelin, B.3
Rudling, M.4
-
29
-
-
34250352437
-
Cell adhesion and cancer: Is there a potential for therapeutic intervention?
-
Lafrenie RM, Buckner CA, Bewick MA. Cell adhesion and cancer: Is there a potential for therapeutic intervention? Expert Opin Ther Targets 2007;11:727-31.
-
(2007)
Expert Opin Ther Targets
, vol.11
, pp. 727-31
-
-
Lafrenie, R.M.1
Buckner, C.A.2
Bewick, M.A.3
-
30
-
-
79952281150
-
Klotho suppresses RIG-I-mediated senescence-associated inflammation
-
Liu F, Wu S, Ren H, Gu J. Klotho suppresses RIG-I-mediated senescence-associated inflammation. Nat Cell Biol 2011;13:254-62.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 254-62
-
-
Liu, F.1
Wu, S.2
Ren, H.3
Gu, J.4
-
31
-
-
70149120326
-
Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice
-
Wu X, Ge H, Lemon B, Weiszmann J, Gupte J, Hawkins N, et al. Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice. Proc Natl Acad Sci U S A 2009;106:14379-84.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14379-84
-
-
Wu, X.1
Ge, H.2
Lemon, B.3
Weiszmann, J.4
Gupte, J.5
Hawkins, N.6
-
32
-
-
78650850911
-
Serum levels of FGF-21 are increased in coronary heart disease patients and are independently associated with adverse lipid profile
-
Lin Z, Wu Z, Yin X, Liu Y, Yan X, Lin S, et al. Serum levels of FGF-21 are increased in coronary heart disease patients and are independently associated with adverse lipid profile. PLoS One 2010;5:e15534.
-
(2010)
PLoS One
, vol.5
-
-
Lin, Z.1
Wu, Z.2
Yin, X.3
Liu, Y.4
Yan, X.5
Lin, S.6
-
33
-
-
20844461345
-
Pretreatment serum FGF-23 levels predict the efficacy of calcitriol therapy in dialysis patients
-
Kazama JJ, Sato F, Omori K,HamaH, Yamamoto S, Maruyama H, et al. Pretreatment serum FGF-23 levels predict the efficacy of calcitriol therapy in dialysis patients. Kidney Int 2005;67:1120-5.
-
(2005)
Kidney Int
, vol.67
, pp. 1120-5
-
-
Kazama, J.J.1
Sato, F.2
Omori, K.3
Hama, H.4
Yamamoto, S.5
Maruyama, H.6
-
34
-
-
77949279533
-
Fibroblast growth factor 19 serum levels: Relation to renal function and metabolic parameters
-
Reiche M, Bachmann A, Lossner U, Bluher M, Stumvoll M, Fasshauer M. Fibroblast growth factor 19 serum levels: Relation to renal function and metabolic parameters. Horm Metab Res 2010;42: 178-81.
-
(2010)
Horm Metab Res
, vol.42
, pp. 178-81
-
-
Reiche, M.1
Bachmann, A.2
Lossner, U.3
Bluher, M.4
Stumvoll, M.5
Fasshauer, M.6
-
35
-
-
77749334660
-
Early control of PTH and FGF23 in normophosphatemic CKD patients: A new target in CKD-MBD therapy?
-
Oliveira RB, Cancela AL, Graciolli FG, Dos Reis LM, Draibe SA, Cuppari L, et al. Early control of PTH and FGF23 in normophosphatemic CKD patients: A new target in CKD-MBD therapy? Clin J Am Soc Nephrol 2010;5:286-91.
-
(2010)
Clin J Am Soc Nephrol
, vol.5
, pp. 286-91
-
-
Oliveira, R.B.1
Cancela, A.L.2
Graciolli, F.G.3
Dos Reis, L.M.4
Draibe, S.A.5
Cuppari, L.6
-
36
-
-
53349160360
-
Serum calcium and incident and fatal prostate cancer in the National Health and Nutrition Examination Survey
-
Skinner HG, Schwartz GG. Serum calcium and incident and fatal prostate cancer in the National Health and Nutrition Examination Survey. Cancer Epidemiol Biomarkers Prev 2008;17:2302-5.
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 2302-5
-
-
Skinner, H.G.1
Schwartz, G.G.2
-
37
-
-
60549085754
-
A prospective study of total and ionized serum calcium and fatal prostate cancer
-
Skinner HG, Schwartz GG. A prospective study of total and ionized serum calcium and fatal prostate cancer. Cancer Epidemiol Biomarkers Prev 2009;18:575-8.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 575-8
-
-
Skinner, H.G.1
Schwartz, G.G.2
-
38
-
-
48349146527
-
Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
-
Zhang X, Yeung DC, Karpisek M, Stejskal D, Zhou ZG, Liu F, et al. Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans. Diabetes 2008;57:1246-53.
-
(2008)
Diabetes
, vol.57
, pp. 1246-53
-
-
Zhang, X.1
Yeung, D.C.2
Karpisek, M.3
Stejskal, D.4
Zhou, Z.G.5
Liu, F.6
-
39
-
-
0021193780
-
Diet, obesity, and risk of fatal prostate cancer
-
Snowdon DA, Phillips RL, Choi W. Diet, obesity, and risk of fatal prostate cancer. Am J Epidemiol 1984;120:244-50.
-
(1984)
Am J Epidemiol
, vol.120
, pp. 244-50
-
-
Snowdon, D.A.1
Phillips, R.L.2
Choi, W.3
-
40
-
-
84859956031
-
Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism
-
Quarles LD. Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism. Nat Rev Endocrinol 2012;8:276-86.
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 276-86
-
-
Quarles, L.D.1
-
41
-
-
75149170979
-
Fibroblast growth factor signalling: From development to cancer
-
Turner N, Grose R. Fibroblast growth factor signalling: From development to cancer. Nat Rev Cancer 2010;10:116-29.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 116-29
-
-
Turner, N.1
Grose, R.2
-
42
-
-
84863940282
-
Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression
-
Feng S, Shao L, Yu W, Gavine P, Ittmann M. Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression. Clin Cancer Res 2012;18:3880-8.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3880-8
-
-
Feng, S.1
Shao, L.2
Yu, W.3
Gavine, P.4
Ittmann, M.5
|