Phosphorylation of the Retinoic Acid Receptor Alpha Induces a Mechanical Allosteric Regulation and Changes in Internal Dynamics

PLoS Computational Biology

Volumn 9, Issue 4, 2013, Pages

  Chebaro, Yassmine ^a   Amal, Ismail ^a   Rochel, Natacha ^a   Rochette Egly, Cécile ^a   Stote, Roland H ^a   Dejaegere, Annick ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BACTERIOPHAGES; CELL DEATH; CHEMICAL ACTIVATION; ENZYMES; LIGANDS; MOLECULAR DYNAMICS; SIGNAL TRANSDUCTION; TRANSCRIPTION; TRANSCRIPTION FACTORS;

ALLOSTERIC REGULATION; AS-LIGANDS; CYCLINS; H-BINDING SITES; INTERNAL DYNAMICS; MECHANICAL; NUCLEAR RECEPTORS; RECEPTORS PROTEINS; RETINOIC ACID RECEPTORS; RETINOIC ACIDS;

PHOSPHORYLATION;

CYCLIN H; RETINOIC ACID RECEPTOR ALPHA;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; HORMONE RECEPTOR INTERACTION; LIGAND BINDING; MOLECULAR DYNAMICS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS REGULATION; PROTEIN TARGETING; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; UPREGULATION;

METAZOA;

EID: 84876907320     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003012     Document Type: Article

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