Plasmacytoid DCs are gentle guardians of tonsillar epithelium

European Journal of Immunology

Volumn 43, Issue 5, 2013, Pages 1142-1146

  Rescigno, Maria ^a  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

Author keywords

Cytokines; Mucosal immunity; Plasmacytoid dendritic cells

Indexed keywords

ALPHA INTERFERON; CD86 ANTIGEN; FLAGELLIN; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; BACTERIAL MEMBRANE; BACTERIAL STRAIN; CELL COMPARTMENTALIZATION; CELL SURFACE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOCYTOSIS; ENDOSOME; EPITHELIUM CELL; ESCHERICHIA COLI; HAEMOPHILUS INFLUENZAE; INTERNALIZATION; MICROFLORA; NEISSERIA MENINGITIDIS; NONHUMAN; NOTE; PHENOTYPE; PLASMACYTOID DENDRITIC CELL; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PYOGENES; SURFACE PROPERTY; T LYMPHOCYTE ACTIVATION; TONSIL CELL; YERSINIA PESTIS;

ADENOIDS; DENDRITIC CELLS; EPITHELIAL CELLS; HUMANS; IMMUNITY, MUCOSAL; RESPIRATORY MUCOSA;

EID: 84876837659     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343533     Document Type: Note

References (26)

1. Hooper, L. V., Littman, D. R. and Macpherson, A. J., Interactions between the microbiota and the immune system. Science 2012. 336: 1268-1273.
2. Lande, R. and Gilliet, M., Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses. Ann. N. Y. Acad. Sci. 2010. 1183: 89-103.
3. Jarrossay, D., Napolitani, G., Colonna, M., Sallusto, F. and Lanzavecchia, A., Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur. J. Immunol. 2001. 31: 3388-3393.
4. Kadowaki, N., Ho, S., Antonenko, S., Malefyt, R. W., Kastelein, R. A., Bazan, F. and Liu, Y. J., Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens. J. Exp. Med. 2001. 194: 863-869.
5. Piccioli, D., Sammicheli, C., Tavarini, S., Nuti, S., Frigimelica, E., Manetti, A. G., Nuccitelli, A. et al., Human plasmacytoid dendritic cells are unresponsive to bacterial stimulation and require a novel type of cooperation with myeloid dendritic cells for maturation. Blood 2009. 113: 4232-4239.
6. Veckman, V. and Julkunen, I., Streptococcus pyogenes activates human plasmacytoid and myeloid dendritic cells. J. Leukoc. Biol. 2008. 83: 296-304.
7. Siegal, F. P., Kadowaki, N., Shodell, M., Fitzgerald-Bocarsly, P. A., Shah, K., Ho, S., Antonenko, S. et al., The nature of the principal type 1 interferon-producing cells in human blood. Science 1999. 284: 1835-1837.
8. Parcina, M., Wendt, C., Goetz, F., Zawatzky, R., Zahringer, U., Heeg, K. and Bekeredjian-Ding, I., Staphylococcus aureus-induced plasmacytoid dendritic cell activation is based on an IgG-mediated memory response. J. Immunol. 2008. 181: 3823-3833.
9. Parcina, M., Miranda-Garcia, M. A., Durlanik, S., Ziegler, S., Over, B., Georg, P., Foermer, S. et al., Pathogen-triggered activation of plasmacytoid dendritic cells induces IL-10-producing B cells in response to Staphylococcus aureus. J. Immunol. 2013. 190: 1591-1602.
10. Michea, P., Vargas, P., Donnadieu, M. H., Rosemblatt, M., Bono, M. R., Dumenil, G. and Soumelis, V., Epithelial control of the human pDC response to extracellular bacteria. Eur. J. Immunol. 2013. 43: 1264-1273.
11. Poth, J. M., Coch, C., Busch, N., Boehm, O., Schlee, M., Janke, M., Zillinger, T. et al., Monocyte-mediated inhibition of TLR9-dependent IFN-alpha induction in plasmacytoid dendritic cells questions bacterial DNA as the active ingredient of bacterial lysates. J. Immunol. 2010. 185: 7367-7373.
12. Kerkmann, M., Costa, L. T., Richter, C., Rothenfusser, S., Battiany, J., Hornung, V., Johnson, J. et al., Spontaneous formation of nucleic acid-based nanoparticles is responsible for high interferon-alpha induction by CpG-A in plasmacytoid dendritic cells. J. Biol. Chem. 2005. 280: 8086-8093.
13. Honda, K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C. et al., Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature 2005. 434: 1035-1040.
14. Guiducci, C., Ott, G., Chan, J. H., Damon, E., Calacsan, C., Matray, T., Lee, K. D. et al., Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation. J. Exp. Med. 2006. 203: 1999-2008.
15. Kim, T., Pazhoor, S., Bao, M., Zhang, Z., Hanabuchi, S., Facchinetti, V., Bover, L. et al., Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells. Proc. Natl. Acad. Sci. USA 2010. 107: 15181-15186.
16. Benitez-Ribas, D., Tacken, P., Punt, C. J., de Vries, I. J. and Figdor, C. G., Activation of human plasmacytoid dendritic cells by TLR9 impairs Fc gammaRII-mediated uptake of immune complexes and presentation by MHC class II. J. Immunol. 2008. 181: 5219-5224.
17. Cao, W., Zhang, L., Rosen, D. B., Bover, L., Watanabe, G., Bao, M., Lanier, L. L. et al., BDCA2/Fc epsilon RI gamma complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells. PLoS Biol. 2007. 5: e248.
18. Tel, J., Benitez-Ribas, D., Hoosemans, S., Cambi, A., Adema, G. J., Figdor, C. G., Tacken, P. J. et al., DEC-205 mediates antigen uptake and presentation by both resting and activated human plasmacytoid dendritic cells. Eur. J. Immunol. 2011. 41: 1014-1023.
19. Meyer-Wentrup, F., Cambi, A., Joosten, B., Looman, M. W., de Vries, I. J., Figdor, C. G. and Adema, G. J., DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production. J. Leukoc. Biol. 2009. 85: 518-525.
20. Schuurhuis, D. H., Lesterhuis, W. J., Kramer, M., Looman, M. G., van Hout-Kuijer, M., Schreibelt, G., Boullart, A. C. et al., Polyinosinic polycytidylic acid prevents efficient antigen expression after mRNA electroporation of clinical grade dendritic cells. Cancer Immunol. Immunother. 2009. 58: 1109-1115.
21. Iliev, I. D., Mileti, E., Matteoli, G., Chieppa, M. and Rescigno, M., Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning. Mucosal Immunol. 2009. 2: 340-350.
22. Iliev, I. D., Spadoni, I., Mileti, E., Matteoli, G., Sonzogni, A., Sampietro, G. M., Foschi, D. et al., Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells. Gut 2009. 58: 1481-1489.
23. Rimoldi, M., Chieppa, M., Larghi, P., Vulcano, M., Allavena, P. and Rescigno, M., Monocyte-derived dendritic cells activated by bacteria or by bacteria-stimulated epithelial cells are functionally different. Blood 2005. 106: 2818-2826.
24. Rimoldi, M., Chieppa, M., Salucci, V., Avogadri, F., Sonzogni, A., Sampietro, G. M., Nespoli, A. et al., Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells. Nat. Immunol. 2005. 6: 507-514.
25. Smythies, L. E., Sellers, M., Clements, R. H., Mosteller-Barnum, M., Meng, G., Benjamin, W. H., Orenstein, J. M. et al., Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity. J. Clin. Invest. 2005. 115: 66-75.
26. Grouard, G., Rissoan, M. C., Filgueira, L., Durand, I., Banchereau, J. and Liu, Y. J., The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand. J. Exp. Med. 1997. 185: 1101-1111.