Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human-Neandertal Divergence

PLoS Genetics

Volumn 9, Issue 4, 2013, Pages

  Gokcumen, Omer ^a,b   Zhu, Qihui ^a,b   Mulder, Lubbertus C F ^c   Iskow, Rebecca C ^a,b   Austermann, Christian ^c   Scharer, Christopher D ^d   Raj, Towfique ^a,b   Boss, Jeremy M ^d   Sunyaev, Shamil ^a,b   Price, Alkes ^e   Stranger, Barbara ^a,b   Simon, Viviana ^c,f   Lee, Charles ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d EMORY UNIVERSITY   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^f Division of Infectious Diseases   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIQUITY; ARTICLE; BALANCING SELECTION; BIOINFORMATICS; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA DETERMINATION; DNA FLANKING REGION; ETHNIC DIFFERENCE; ETHNIC GROUP; EURASIAN; EVOLUTIONARY ADAPTATION; GENE; GENE CONTROL; GENE DELETION; GENE FUNCTION; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HAPLOTYPE; HOMO NEANDERTHALENSIS; HUMAN; HUMAN GENOME; HUMAN VERSUS ANIMAL COMPARISON; NE1 GENE; NEGRO; PALEOANTHROPOLOGY; POPULATION GENETICS; REGULATORY DNA SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ANIMALS; BASE SEQUENCE; ETHNIC GROUPS; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC VARIATION; GENETICS, POPULATION; GENOME, HUMAN; HAPLOTYPES; HUMANS; NEANDERTHALS; PAN TROGLODYTES; PHYLOGENY; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION, GENETIC; SEQUENCE DELETION;

PAN;

EID: 84876836372     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003404     Document Type: Article

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