Rapid screening of bioactive compounds from natural products by integrating 5-channel parallel chromatography coupled with on-line mass spectrometry and microplate based assays

Analytica Chimica Acta

Volumn 777, Issue , 2013, Pages 49-56

  Zhang, Yufeng ^a   Xiao, Shun ^a   Sun, Lijuan ^a   Ge, Zhiwei ^a   Fang, Fengkai ^b   Zhang, Wen ^b   Wang, Yi ^a   Cheng, Yiyu ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Natural products; Parallel chromatography; Rapid identification; Targeted screening; Traditional Chinese medicine

Indexed keywords

ANTI-TUMOR ACTIVITIES; CHROMATOGRAPHIC SEPARATIONS; HIGH-THROUGHPUT METHOD; NATURAL PRODUCTS; ONLINE MASS SPECTROMETRY; RAPID IDENTIFICATION; TARGETED SCREENINGS; TRADITIONAL CHINESE MEDICINE;

DIAGNOSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

BIOTECHNOLOGY;

4 CAFFEOYLQUINIC ACID; 5 CAFFEOYLQUINIC ACID; AGELASIN B; AGELASINE D; ANTIOXIDANT; CHLOROGENIC ACID; DEHYDROXYL RABDOSIIN; GLYCOPYRANOSIDE; GLYCYRRHIZIC ACID; ISOQUERCITRIN; NATURAL PRODUCT; NATURAL PRODUCTS AND THEIR SYNTHETIC DERIVATIVES; NICOTIFLORIN; RABDOSIIN; ROSMARINIC ACID; RUBESCENSIN A; RUTOSIDE; SALVIANOLIC ACID A; SALVIANOLIC ACID B; TANGERETIN; TAXIFOLIN; UNCLASSIFIED DRUG; VICENIN 2;

AGELAS; AGELAS MAURITIANA; ANALYTIC METHOD; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL STRAIN MCF 7; CHINESE MEDICINE; CONTROLLED STUDY; DRUG SCREENING; ENZYME ASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; IC 50; MASS SPECTROMETRY; MICROPLATE BASED ASSAY; NONHUMAN; PRIORITY JOURNAL; RABDOSIA; RABDOSIA RUBESCENS; REPRODUCIBILITY;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; BIOLOGICAL AGENTS; BIOLOGICAL ASSAY; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG STABILITY; HL-60 CELLS; HUMANS; MASS SPECTROMETRY; PORIFERA; REPRODUCIBILITY OF RESULTS; TIME FACTORS;

AGELAS MAURITIANA;

EID: 84876809698     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2013.03.028     Document Type: Article

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